Page 3«..2345..1020..»

Category : Testosterone Physicians

Testosterone Replacement Therapy – Men’s Health Clinic NZ

What is Testosterone?Testosterone is the hormone produced by the testicles. It is responsible for the proper development of male sexual characteristics. It helps promote the circulation of blood, and is responsible for the maintenance of muscle bulk. Without an adequate testosterone level there can be important psychological affects such as loss of libido, reduced brain and intellectual activity and mood changes.What causes the Andropause? As all men age there is a gradual decline in the level of testosterone. This natural decline starts after 30 and continues throughout life. By the age of 40, testosterone levels drop by 1% every year. Many men however can experience a lack of testosterone production sufficient to result in significant symptoms. This will apply to approximately 50% of men by age 55. Damaged testicles or disease will affect testosterone production as will long-term stress, smoking and excessive alcohol consumption. In 60% of cases no cause can be identified and hereditary factors are implicated. Are there any health issues associated with the Andropause? Low levels of testosterone may result in an increase in tummy and chest fat, a decline in the amount of muscle in the body and decline in strength. Low levels can also lead to Brittle bones, (osteoporosis) which may lead to hip and spinal fractures. In addition the bone marrow is less active and produces less haemoglobin and red blood cells to transport oxygen around the body.

A consultation is required and blood tests will be necessary. The blood tests include an examination for prostate cancer, as this is a contraindication to testosterone treatment. Any suspicion of prostate cancer may require further investigations. The aim of therapy is to return the blood testosterone level in the bloodstream to the normal range for the man’s age. This is achieved by using bio-identical testosterone cream that is rubbed onto the skin daily.

IF YOU THINK YOU MIGHT HAVE LOW TESTOSTERONE, check out our quick online self assessment test.

More here:
Testosterone Replacement Therapy – Men’s Health Clinic NZ

Recommendation and review posted by Alexandra Lee Anderson

Testosterone Side Effects in Detail – Drugs.com

For the Consumer

Applies to testosterone: buccal patch extended release

Along with its needed effects, testosterone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking testosterone:

Get emergency help immediately if any of the following symptoms of overdose occur while taking testosterone:

Some side effects of testosterone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Applies to testosterone: buccal film extended release, compounding powder, intramuscular solution, nasal gel, subcutaneous implant, transdermal cream, transdermal film extended release, transdermal gel, transdermal ointment, transdermal solution

The most frequently reported side effects with this drug are edema, acne, site pain, injection site erythema, cough or dyspnea during or immediately after injection.

The most frequently reported side effects with testosterone topical are skin reaction (16.1%) and allergic contact dermatitis (up to 37%).[Ref]

Very common (10% or more): Testosterone topical: Skin reaction (16.1%), burn-like blisters (12%), itching, allergic contact dermatitis (up to 37%)Common (1% to 10%): Acne, induration, burningUncommon (0.1% to 1%): Alopecia, erythema, rash (including rash popular), pruritus, dry skin, folliculitis (testosterone topical)Frequency not reported: Seborrhea, urticaria, male pattern baldness, hirsutism injection site inflammationPostmarketing reports: Angioedema, angioneurotic edema, hyperhidrosis, discolored hair, leukocytoclastic vasculitis[Ref]

Very common (10% or more): Accelerated growthCommon (1% to 10%): Increased estradiol, hypogonadismUncommon (0.1% to 1%): Increased blood testosteroneFrequency not reported: Signs of virilization in women (e.g., hoarseness, acne, hirsutism, menstrual irregularity, clitoral enlargement, and alopecia), precocious puberty (in prepubertal males)Postmarketing reports: Hyperparathyroidism, prolactin increased, testosterone increased[Ref]

Very common (10% or more): Testosterone buccal film: Gingivitis (32.6%)Common (1% to 10%): Diarrhea, oily stools (due to IM injection oily solvent); Testosterone topical: Gastroesophageal reflux disease, gastrointestinal bleeding, gum or mouth irritation (9.2%), taste bitter, gum pain, gum tenderness, gum edema, taste perversionUncommon (0.1% to 1%): NauseaRare (less than 0.1%): Abdominal painFrequency not reported: Abdominal disorder, intraabdominal hemorrhagePostmarketing reports: Vomiting; Testosterone buccal film: Dry mouth, gingival swelling, lip swelling, mouth ulceration, stomatitis[Ref]

The majority of gum-related adverse events were transient.[Ref]

Very common (10% or more): Testosterone topical: Application site pruritus (up to 37%), application site blistering (12%)Common (1% to 10%): Injection site pain, injection site discomfort, injection site pruritus, erythema, injection site hematoma, injection site irritation, injection site inflammation; injection site reaction; Topical testosterone: Application site erythema, application site warmth, application site irritation, application site vesicles, application site exfoliation, application site burning, application site induration, bullae at application site, mechanical irritation at application site, rash at application site, contamination of application sitePostmarketing reports: Injection site abscess, procedural pain, application site swelling (topical testosterone)[Ref]

Common (1% to 10%): Hot flush, hypertensionUncommon (0.1% to 1%): Cardiovascular disorderFrequency not reported: Venous thromboembolismPostmarketing reports: Angina pectoris, cardiac arrest, cardiac failure, coronary artery disease, coronary artery occlusion, myocardial infarction, tachycardia, cerebral infarction, cerebrovascular accident, circulatory collapse, deep venous thrombosis, syncope, thromboembolism, thrombosis, venous insufficiency, stroke[Ref]

Common (1% to 10%): Abnormal prostate examination, benign prostate hyperplasia (BPH), ejaculation disorder, prostatitisUncommon (0.1% to 1%): Prostate induration, prostatic disorder, testicular pain, decreased urine flow, urinary retention, urinary tract disorder, nocturia, dysuriaRare (less than 0.1%): Micturition disorders, epididymitis, bladder irritability, impotence, inhibition of testicular function and testicular atrophyFrequency not reported: Oligospermia, priapism, benign prostatic hyperplasia (prostatic growth to eugonadal state), excessive frequency and duration of erections; Pediatrics: Precocious sexual development, an increased frequency of erections, phallic enlargementPostmarketing reports: Prostate infection, calculus urinary, dysuria, hematuria, urinary tract disorder, pollakiuria[Ref]

Common (1% to 10%): Polycythemia, hematocrit increasedUncommon (0.1% to 1%): Increased red blood cell count, increased hemoglobin, prolonged activated partial thromboplastin time, prolonged prothrombin timeFrequency not reported: Blood and lymphatic system disorders, suppression of clotting factors II, V, VII, and X, bleeding in patients on concomitant anticoagulant therapyPostmarketing reports: Thrombocytopenia, anemia[Ref]

Common (1% to 10%): Weight increased, appetite increased, fluid retention (sodium, chloride, water, potassium, calcium, and inorganic phosphates)Uncommon (0.1% to 1%): Increased glycosylated hemoglobin, hypercholesterolemia, increased triglycerideFrequency not reported: Abnormal lipids (decrease in serum LDL, HDL, and triglycerides), metabolism and nutrition disorders, hypercalcemiaPostmarketing reports: Hypoglycemia, diabetes mellitus, fluid retention, hyperlipidemia, hypertriglyceridemia, blood glucose increased[Ref]

Common (1% to 10%): Back pain, hemarthrosis (testosterone topical)Uncommon (0.1% to 1%): Arthralgia, pain in extremity, muscle spasm, muscle strain, myalgia, musculoskeletal stiffness, increased creatine phosphokinaseFrequency not reported: Pediatrics: Premature epiphyseal closure, increased bone formationPostmarketing reports: Musculoskeletal chest pain, musculoskeletal pain, myalgia, osteopenia, osteoporosis, systemic lupus erythematosus[Ref]

Common (1% to 10%): Headache, vertigo (topical testosterone)Uncommon (0.1% to 1%): Migraine, tremor, dizzinessFrequency not reported: Nervousness, paresthesiaPostmarketing reports: Cerebrovascular insufficiency, reversible ischemic neurological deficiency, transient ischemic attack, amnesia[Ref]

Common (1% to 10%): Prostatic specific antigen (PSA) increased, prostate cancerUncommon (0.1% to 1%): Prostatic intraepithelial neoplasiaRare (less than 0.1%): Neoplasms benign, malignant, and unspecified (including cysts and polyps)[Ref]

Common (1% to 10%): Fatigue, hyperhidrosis; chills, body pain, smell disorderUncommon (0.1% to 1%): Breast induration, breast pain, sensitive nipples, gynecomastia, increased estradiol, increased testosterone, asthenia, night sweats Rare (less than 0.1%): Fever, malaiseFrequency not reported: EdemaPostmarketing reports: Sudden hearing loss, tinnitus, Influenza like illness[Ref]

Common (1% to 10%): Irritability, insomnia, mood swings, aggression,Uncommon (0.1% to 1%): Depression, emotional disorder, restlessness, increased libido, decreased libidoFrequency not reported: Hostility, anxietyPostmarketing reports: Korsakoff’s psychosis nonalcoholic, male orgasmic disorder, restlessness, sleep disorder[Ref]

Common (1% to 10%): Sinusitis, nasopharyngitis, upper respiratory tract infection, bronchitisUncommon (0.1% to 1%): Cough, dyspnea, snoring, dysphoniaRare (less than 0.1%): Pulmonary microembolism (POME) (cough, dyspnea, malaise, hyperhidrosis, chest pain, dizziness, paresthesia, or syncope) caused by oily solutionsFrequency not reported: Sleep apneaPostmarketing reports: Chest pain, asthma, chronic obstructive pulmonary disease, hyperventilation, obstructive airway disorder, pharyngeal edema, pharyngolaryngeal pain, pulmonary embolism, respiratory distress, rhinitis, sleep apnea syndrome[Ref]

Signs and symptoms of pulmonary microemboli may occur during or immediately after the injections and are reversible.[Ref]

Uncommon (0.1% to 1%): Abnormal LFT, increased ASTRare (less than 0.1%): Abnormal hepatic functionFrequency not reported: Jaundice, benign liver tumor, malignant liver tumor, liver enlargement, peliosis hepatitisPostmarketing reports: ALT increased, AST increased, bilirubin increased, transaminases increased, gamma-glutamyltransferase increased[Ref]

Uncommon (0.1% to 1%): Hypersensitivity reactionsFrequency not reported: Anaphylactic reactionsPostmarketing reports: Anaphylactic shock[Ref]

Uncommon (0.1% to 1%): Testosterone topical: Lacrimation increasedPostmarketing reports: Testosterone topical: Intraocular pressure increased, vitreous detachment[Ref]

Postmarketing reports: Nephrolithiasis, renal colic, renal pain[Ref]

1. “Product Information. Fortesta (testosterone).” Endo Pharmaceuticals (formally Indevus Pharmaceuticals Inc), Lexington, MA.

2. “Product Information. AndroGel (testosterone).” Unimed Pharmaceuticals, Buffalo Grove, IL.

3. Cerner Multum, Inc. “Australian Product Information.” O 0

4. “Product Information. Testosterone Enanthate (testosterone).” West-Ward Pharmaceutical Corporation, Eatontown, NJ.

5. Cerner Multum, Inc. “UK Summary of Product Characteristics.” O 0

6. “Product Information. Axiron (testosterone).” Lilly, Eli and Company, Indianapolis, IN.

7. “Product Information. Testopel (testosterone).” Bartor Pharmacal Co, Inc, Rye, NY.

8. “Product Information. Aveed (testosterone).” Endo Pharmaceuticals Solutions Inc, Malvern, PA.

9. “Product Information. Testim (testosterone).” A-S Medication Solutions, Chicago, IL.

10. “Product Information. Androderm (testosterone topical).” SmithKline Beecham, Philadelphia, PA.

11. “Product Information. Depo-Testosterone (testosterone).” Pfizer U.S. Pharmaceuticals Group, New York, NY.

12. Bates GW, Cornwell CE “Iatrogenic causes of hirsutism.” Clin Obstet Gynecol 34 (1991): 848-51

13. Dobs AS, Meikle AW, Arver S, Sanders SW, Caramelli KE, Mazer NA “Pharmacokinetics, efficacy, and safety of a permeation-enhanced testosterone transdermal system in comparison with bi-weekly injections of testosterone enanthate for the treatment of hypogonadal men.” J Clin Endocrinol Metab 84 (1999): 3469-78

14. O’Driscoll JB, August PJ “Exacerbation of psoriasis precipitated by an oestradiol-testosterone implant.” Clin Exp Dermatol 15 (1990): 68-9

15. Fyrand O, Fiskaadal HJ, Trygstad O “Acne in pubertal boys undergoing treatment with androgens.” Acta Derm Venereol 72 (1992): 148-9

16. Traupe H, von Muhlendahl KE, Bramswig J, Happle R “Acne of the fulminans type following testosterone therapy in three excessively tall boys.” Arch Dermatol 124 (1988): 414-7

17. Wu FC, Farley TM, Peregoudov A, Waites GM “Effects of testosterone enanthate in normal men: experience from a multicenter contraceptive efficacy study. World Health Organizatio Task Force on Methods for the Regulation of Male Fertility.” Fertil Steril 65 (1996): 626-36

18. Bennett NJ “A burn-like lesion caused by a testosterone transdermal system.” Burns 24 (1998): 478-80

19. Buckley DA, Wilkinson SM, Higgins EM “Contact allergy to a testosterone patch.” Contact Dermatitis 39 (1998): 91-2

20. DeSanctis V, Vullo C, Urso L, Rigolin F, Cavallini A, Caramelli K, Daugherty C, Mazer N “Clinical experience using the Androderm (R) testosterone transdermal system in hypogonadal adolescents and young men with beta-thalassemia major.” J Pediatr Endocrinol Metab 11 (1998): 891-900

21. Cefalu WT, Pardridge WM, Premachandra BN “Hepatic bioavailability of thyroxine and testosterone in familial dysalbuminemic hyperthyroxinemia.” J Clin Endocrinol Metab 61 (1985): 783-6

22. Matsumoto AM “Effects of chronic testosterone administration in normal men: safety and efficacy of high dosage testosterone and parallel dose-dependent suppression of luteinizing hormone, follicle-stimulating hormone, and sperm production.” J Clin Endocrinol Metab 70 (1990): 282-7

23. Tripathy D, Shah P, Lakshmy R, Reddy KS “Effect of testosterone replacement on whole body glucose utilisation and other cardiovascular risk factors in males with idiopathi hypogonadotrophic hypogonadism.” Horm Metab Res 30 (1998): 642-5

24. Becker U, Gluud C, Bennett P “The effect of oral testosterone on serum TBG levels in alcoholic cirrhotic men.” Liver 8 (1988): 219-24

25. Ferrera PC, Putnam DL, Verdile VP “Anabolic steroid use as the possible precipitant of dilated cardiomyopathy.” Cardiology 88 (1997): 218-20

26. Jackson JA, Waxman J, Spiekerman AM “Prostatic complications of testosterone replacement therapy.” Arch Intern Med 149 (1989): 2365-6

27. Zelissen PM, Stricker BH “Severe priapism as a complication of testosterone substitution therapy.” Am J Med 85 (1988): 273-4

28. Wang C, Leung A, Superlano L, Steiner B, Swerdloff RS “Oligozoospermia induced by exogenous testosterone is associated with normal functioning residual spermatozoa.” Fertil Steril 68 (1997): 149-53

29. Endres W, Shin YS, Rieth M, Block T, Schmiedt E, Knorr D “Priapism in Fabry’s disease during testosterone treatment.” Klin Wochenschr 65 (1987): 925

30. Parker LU, Bergfeld WF “Virilization secondary to topical testosterone.” Cleve Clin J Med 58 (1991): 43-6

31. Zhang GY, Gu YQ, Wang XH, Cui YG, Bremner WJ “A clinical trial of injectable testosterone undecanoate as a potential male contraceptive in normal Chinese men.” J Clin Endocrinol Metab 84 (1999): 3642-7

32. Anderson FH, Francis RM, Faulkner K “Androgen supplementation in eugonadal men with osteoporosis-effects of 6 months of treatment on bone mineral density and cardiovascula risk factors.” Bone 18 (1996): 171-7

33. Bhasin S, Storer TW, Javanbakht M, et al. “Testosterone replacement and resistance exercise in HIV-infected men with weight loss and low testosterone levels.” JAMA 283 (2000): 763-70

34. Bagatell CJ, Heiman JR, Matsumoto AM, Rivier JE, Bremner WJ “Metabolic and behavioral effects of high-dose, exogenous testosterone in healthy men.” J Clin Endocrinol Metab 79 (1994): 561-7

35. Lajarin F, Zaragoza R, Tovar I, Martinezhernandez P “Evolution of serum lipids in two male bodybuilders using anabolic steroids.” Clin Chem 42 (1996): 970-2

36. Zmuda JM, Thompson PD, Dickenson R, Bausserman LL “Testosterone decreases lipoprotein(a) in men.” Am J Cardiol 77 (1996): 1244

37. Stannard JP, Bucknell AL “Rupture of the triceps tendon associated with steroid injections.” Am J Sports Med 21 (1993): 482-5

38. Pollard M “Tumorigenic effect of testosterone.” Lancet 336 (1990): 1518

39. Uzych L “Anabolic-androgenic steroids and psychiatric-related effects: a review.” Can J Psychiatry 37 (1992): 23-8

40. Nuzzo JL, Manz HJ, Maxted WC “Peliosis hepatis after long-term androgen therapy.” Urology 25 (1985): 518-9

41. Carrasco D, Prieto M, Pallardo L, Moll JL, Cruz JM, Munoz C, Berenguer J “Multiple hepatic adenomas after long-term therapy with testosterone enanthate. Review of the literature.” J Hepatol 1 (1985): 573-8

42. Yu MW, Chen CJ “Elevated serum testosterone levels and risk of hepatocellular carcinoma.” Cancer Res 53 (1993): 790-4

43. Falk H, Thomas LB, Popper H, Ishak KG “Hepatic angiosarcoma associated with androgenic-anabolic steroids.” Lancet 2 (1979): 1120-3

Some side effects of testosterone may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

Read the original:
Testosterone Side Effects in Detail – Drugs.com

Recommendation and review posted by Alexandra Lee Anderson

Is testosterone therapy safe? Take a breath before you …

Understand the potential risks and consider alternatives before boosting your hormones indefinitely.

Millions of American men use a prescription testosterone gel or injection to restore normal levels of the manly hormone. The ongoing pharmaceutical marketing blitz promises that treating “low T” this way can make men feel more alert, energetic, mentally sharp, and sexually functional. However, legitimate safety concerns linger. For example, some older men on testosterone could face higher cardiac risks.

“Because of the marketing, men have been flooded with information about the potential benefit of fixing low testosterone, but not with the potential costs,” says Dr. Carl Pallais, an endocrinologist and assistant professor of medicine at Harvard Medical School. “Men should be much more mindful of the possible long-term complications.”

MIND Depression Reduced self-confidence Difficulty concentrating Disturbed sleep

BODY Declining muscle and bone mass Increased body fat Fatigue Swollen or tender breasts Flushing or hot flashes

SEXUAL FUNCTION Lower sex drive Fewer spontaneous erections Difficulty sustaining erections

Images: Thinkstock

A loophole in FDA regulations allows pharmaceutical marketers to urge men to talk to their doctors if they have certain “possible signs” of testosterone deficiency. “Virtually everybody asks about this now because the direct-to-consumer marketing is so aggressive,” says Dr. Michael O’Leary, a urologist at Harvard-affiliated Brigham and Women’s Hospital. “Tons of men who would never have asked me about it before started to do so when they saw ads that say ‘Do you feel tired?’”

Just being tired isn’t enough to get a testosterone prescription. “General fatigue and malaise is pretty far down my list,” Dr. O’Leary says. “But if they have significant symptoms, they’ll need to have a lab test. In most men the testosterone level is normal.”

If a man’s testosterone looks below the normal range, there is a good chance he could end up on hormone supplementsoften indefinitely. “There is a bit of a testosterone trap,” Dr. Pallais says. “Men get started on testosterone replacement and they feel better, but then it’s hard to come off of it. On treatment, the body stops making testosterone. Men can often feel a big difference when they stop therapy because their body’s testosterone production has not yet recovered.”

This wouldn’t matter so much if we were sure that long-term hormone therapy is safe, but some experts worry that low-T therapy is exposing men to small risks that could add up to harm over time.

A relatively small number of men experience immediate side effects of testosterone supplementation, such as acne, disturbed breathing while sleeping, breast swelling or tenderness, or swelling in the ankles. Doctors also watch out for high red blood cell counts, which could increase the risk of clotting.

The evidence for long-term risks is mixed. Some studies have found that men on testosterone have fewer cardiovascular problems, like heart attacks, strokes, and deaths from heart disease. Other studies have found a higher cardiac risk. For example, in 2010, researchers halted the Testosterone in Older Men study when early results showed that men on hormone treatments had noticeably more heart problems. “In older men, theoretical cardiac side effects become a little more immediate,” Dr. Pallais says.

Some physicians also have a lingering concern that testosterone therapy could stimulate the growth of prostate cancer cells. As with the hypothetical cardiac risks, the evidence is mixed. But because prostate cancer is so common, doctors tend to be leery of prescribing testosterone to men who may be at risk.

“Like any treatment, there is risk,” Dr. O’Leary says. “I would not give it to a man who is being treated for active prostate cancer, but it’s pretty safe under careful supervision for those who need it.”

For the time being, the long-term risks of testosterone therapy are “known unknowns.” It offers men who feel lousy a chance to feel better, but that quick fix could distract attention from unknown long-term hazards. “I can’t tell you for certain that this raises the risk of heart problems and prostate cancer, or that it doesn’t,” Dr. Pallais says. “We need a large study with multiple thousands of people followed for many years to figure it out.”

So, keep risks in mind when considering testosterone therapy. “I frequently discourage it, particularly if the man has borderline levels,” Dr. Pallais says.

These steps can help you feel more energetic today without drugs or dietary supplements:

Pace yourself: Spread out activities throughout the day.

Take a walk: It gives you a lift when you feel pooped out.

Snack smart: Have a snack with fiber and some protein between meals.

A large, definitive trial for hormone treatment of men is still to come. Until then, here is how to take a cautious approach to testosterone therapy.

Have you considered other reasons why you may be experiencing fatigue, low sex drive, and other symptoms attributable to low testosterone? For example, do you eat a balanced, nutritious diet? Do you exercise regularly? Do you sleep well? Address these factors before turning to hormone therapy.

If your sex life is not what it used to be, have you ruled out relationship or psychological issues that could be contributing?

If erectile dysfunction has caused you to suspect “low T” as the culprit, consider that cardiovascular disease can also cause erectile dysfunction.

Inaccurate or misinterpreted test results can either falsely diagnose or miss a case of testosterone deficiency. Your testosterone level should be measured between 7 am and 10 am, when it’s at its peak. Confirm a low reading with a second test on a different day. It may require multiple measurements and careful interpretation to establish bioavailable testosterone, or the amount of the hormone that is able to have effects on the body. Consider getting a second opinion from an endocrinologist.

After starting therapy, follow-up with your physician periodically to have testosterone checks and other lab tests to make sure the therapy is not causing any problems with your prostate or blood chemistry.

Approach testosterone therapy with caution if you are at high risk for prostate cancer; have severe urinary symptoms from prostate enlargement; or have diagnosed heart disease, a previous heart attack, or multiple risk factors for heart problems.

Ask your doctor to explain the various side effects for the differentformulations of testosterone, such as gels, patches, and injections. Know what to look for if something goes wrong.

Testosterone therapy is not a fountain of youth. There is no proof that it will restore you to the level of physical fitness or sexual function of your youth, make you live longer, prevent heart disease or prostate cancer, or improve your memory or mental sharpness. Do not seek therapy with these expectations in mind.

If erectile function has been a problem, testosterone therapy might not fix it. In fact, it might increase your sex drive but not allow you to act on it. You may also need medication or other therapy for difficulty getting or maintaining erections.

Go here to see the original:
Is testosterone therapy safe? Take a breath before you …

Recommendation and review posted by Alexandra Lee Anderson

Dont Be Fooled: The Difference Between Testosterone …

Testosterone Booster vs. Replacement

Testosterone, while mostly thought of as the hormone that makes a male a man, there is more to its functions in the body. Testosterone is not only primarily responsible for the sex drive, it is also important for mans vitality, strength, agility and vigor. It is also important to women because it plays an intrinsic role in keeping them sexually active.

Summarily, it is often referred to as the elixir of youth, thanks to its ability to keep men feeling young and agile. Unfortunately, once you it the big 30, your testosterone levels start to decrease. This decline often results in depression, low libido, erectile dysfunction, difficulty in achieving orgasms, low ejaculation volume, impaired memory and poor concentration.

The combination of all these conditions is called hypogonadism. When this happens for a prolonged period of time and they are diagnosed with the LOW-T condition, most men start looking for solutions in the form of testosterone boosters and replacement therapy. Which brings us to the important question: Whats the difference between testosterone replacement therapy and testosterone boosters?

This is important because there is a clear difference between the two even though many often use the terms interchangeably.

Simply put, testosterone boosters are supplements that are used to help bodybuilders build more mass and strength. Also known as an alternative to anabolic steroids, this is nowhere near the real deal. T-Boosters as they are popularly called, are meant to help you do more and achieve more results whilst working out and training. Think of it as a steroid of sorts.

Only this time, its uncharted waters as evidenced by the lack of approval by the FDA. There are no known proofs of it being able to help boost your testosterone levels apart from the usual testosterone boost you get from high intensity workouts- no matter how much thats used in the products sales copies. All reports about testosterone boosters being able to help increase motivation seems unfounded and lacking in authenticity.

On the other hand, testosterone therapy is known for its effectiveness at boosting and increasing the testosterone levels of people who are suffering from hypogonadism. Its often known to help them become more agile, more enthusiastic, increases, their sense of well-being and sex drive, whilst eliminating problems like erectile dysfunction, depression, fatigue and poor concentration. There are quite a few testosterone replacement therapies.

Usually, talking to your doctor about how you feel will help them decide on what therapy method would best suit you. Many patients have recorded tremendous improvements on their testosterone levels through the impact of exogenous testosterone treatment regimens. Testosterone replacement therapies often include the use of testosterone patches, testosterone, topical gels and testosterone injections.

Men who have used testosterone gels often notice an increase in their testosterone levels to about 500-600 ng/dl (the normal testosterone levels) as against the 300 ng/dl levels observed in men diagnosed with Low-T. While there are testosterone pills, their use is largely discouraged because of their significant impact in liver toxicity.

Testosterone patches can be either scrotal or non-scrotal and are also known to be effective in increasing the bodys T-levels. The downside to using this however is that it tends to irritate the skin. Testosterone gels are known to be significantly absorbed by the skin and have a near-instant absorption rate which lasts throughout the day. And theres also the buccal testosterone which is known to produce even better results than the patches when applied to the gums. The side effects of that however often include bitter taste in the mouth and some irritation to the gums.

As you can see, testosterone boosters are clearly not the same thing as testosterone replacement. So, if you feel that you be might suffering from Low-T, consult with your doctors and let them place you on the necessary testosterone replacement therapies instead of self-medicating with testosterone boosters.

Sources:

http://www.harvardprostateknowledge.org/a-harvard-expert-shares-his-thoughts-on-testosterone-replacement-therapy

http://www.webmd.com/erectile-dysfunction/guide/testosterone-replacement-therapy

http://www.health.harvard.edu/press_releases/is-testosterone-replacement-therapy-safe

http://www.webmd.com/men/guide/testosterone-replacement-therapy-is-it-right-for-you0

Here is the original post:
Dont Be Fooled: The Difference Between Testosterone …

Recommendation and review posted by Alexandra Lee Anderson

Testosterone Replacement Therapy – Ehormones

The most effective delivery method for Testosterone Replacement Therapy (or TRT) is Testosterone injections. Testosterone Replacement Therapy typically requires weekly Testosterone injections and ancillary medications, where necessary. These may include medications which allow the testes to continue its natural production of testosterone while on TRT, and an Aromatase Inhibitor, typically in pill form, to suppress the bodys conversion of Testosterone to Estrogen.

Every man has his own unique set of circumstances and must be treated as an individual. Therefore, EHormonesMD managed physicians perform physical examinations on every patient, in addition to using a combination of comprehensive, diagnostic lab work, feedback from the patient himself, as well as medical history and symptomology to determine the patients individual Testosterone Therapy regimen. However, it is important to note that not every adult male will be a candidate for Testosterone Replacement Therapy. This is why its very important that you speak with a doctor who specializes in treating Low Testosterone in adult men.

Ask yourself if you suffer from one or more of the following:

Original post:
Testosterone Replacement Therapy – Ehormones

Recommendation and review posted by Alexandra Lee Anderson

New Jersey Testosterone Therapy Clinics – AAI Clinic

New Jersey Testosterone Therapy Clinics.In a multi-institutional study to understand the effects of testosterone treatment in men age 30 and older, researchers found improved sexual function, walking ability and mood. The study, conducted by 12 institutions including Baylor College of Medicine in partnership with the National Institute on Anti-Aging, appears today in the New England Journal of Medicine.

This is the largest to date and most rigorously conducted trial evaluating the benefits of testosterone Injections in older men with low testosterone levels, said Dr. Glenn Cunningham, distinguished professor emeritus in the department of medicine endocrinology at Baylor. Cunningham served as the principal investigator for the Baylor site and as a member of the steering committee for the trials. However, our trial is not large enough nor did it last long enough to determine potential risks of testosterone replacement Therapy.

As men age, their testosterone levels decrease, and previous studies on the effects of testosterone Therapy treatment in older men have been inconclusive. Researchers studied testosterone treatment in men 65 and older whose testosterone levels were low due to age alone. The 790 men enrolled in the trials were randomized into two groups one applying a testosterone gel daily and the other applying a placebo gel daily.

For this study, researchers conducted a coordinated group of seven trials and have now published the results of the first three: sexual function, physical function, and vitality. They found that testosterone Injections treatment increased the blood testosterone level to mid-normal for young men and improved all aspects of sexual function, including sexual activity, sexual desire and the ability to get an erection. When researchers evaluated only men enrolled in the physical function trial, the treatment did not significantly improve distance walked in six minutes, but when all men in the trials were considered, it did show an increase in distance walked. The study also showed that the treatment improved mood and depressive symptoms.

Researchers concluded that a larger and longer study needed to be conducted to understand the risks of the treatment.

The Perelman School of Medicine at the University of Pennsylvania was the coordinating site for the study. Other institutions taking part in the study included Albert Einstein College of Medicine, Brigham and Womens Hospital, Harbor-UCLA Medical Center, University of Alabama at Birmingham, Northwestern University Feinberg School of Medicine, Puget Sound Health Care System, University of California at San Diego School of Medicine, University of Florida School of Medicine, University of Minnesota School of Medicine, University of Pittsburgh School of Public Health, and Yale School of Medicine.

Please contact our clinic Support to schedule an appointment on one of this New Jersey Testosterone Therapy Clinics blood center Clinics Near you.

More here:
New Jersey Testosterone Therapy Clinics – AAI Clinic

Recommendation and review posted by Alexandra Lee Anderson

Side Effects of Testosterone Replacement Therapy (TRT)

As with any medical intervention, the benefits of Low T therapy must be weighed against the potential risk of adverse reactions the side effects of testosterone replacement therapy can be a problem if not properly managed by a trained provider.

Just as Paracelsus says, whether testosterone replacement creates a poisonous or beneficial environment is largely dependent upon how the medication is delivered and dosed.

Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy. Paracelsus

Those who abuse testosterone and other androgens may experience significant and even life threatening side effects.

Somewhat similarly, if treatment of Low T is mismanaged or not carefully monitored, patients will experience a higher rate and increased severity of adverse reactions or possibly a complete lack of meaningful results.

For the most part, this discussion will deal with the side effects of testosterone replacement therapy (TRT) in general, but some attention will be given to particular differences in the variety of methods utilized for treatment of Low T.

You can also watch the video below to hear from one of our founding partners, Augie Galindo, PA-C about the side effects of testosterone replacement therapy.

This video is about the Side Effects of TRT. Every medical intervention has potential issues, and treating Low T is no different. Learn about our approach to monitor and maintain safe testosterone levels.

Some side effects seen with TRT are the direct result of the use of exogenous testosterone (testosterone not made naturally in the body).

Pharmaceutical grade testosterone is bio-identical, that is, it is constructed, recognized, and utilized in the same manner as the hormone produced by your body.

Many adverse effects occur only in the presence of higher testosterone levels, and still others are simply the consequences of the bodys normal metabolism of testosterone.

This metabolism, or breakdown of testosterone, occurs in the same manner for both exogenous and endogenous testosterone (naturally produced testosterone), but because of an increased abundance of testosterone this may lead to higher than normal levels of these metabolites.

Normal metabolism of testosterone results in its conversion into two primary metabolites, dihydrotestosterone (DHT) and estradiol (E2, a form of estrogen).

Elevated levels of DHT can cause benign growth of the prostate, increased oiliness of the skin and acne, as well as male pattern balding.

Abnormal increases in estradiol can lead to mood swings, breast tissue changes, and fluid retention that may cause swelling or increases in blood pressure. Furthermore, abnormal estradiol levels have been linked to lower testosterone levels, erectile dysfunction, and a decrease in free testosterone.

According to the 2010 update to Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline, the conversion rate and subsequent ratio of testosterone to estradiol and DHT does not change when treating Low T via injection of testosterone cypionate.

These ratios may be negatively affected with other Low T treatments (gels, patches, pellets, etc.).

While prostate changes can occur with testosterone replacement, a study published in The Journal of Clinical Endocrinology & Metabolism in June of 2010, which looked closely at the adverse reactions reported in 51 other studies, found there to be no increased risk of the development of prostate cancer, prostate related urinary symptoms, or elevated PSA (prostate specific antigen).

Basically, prostate cancer is NOT one of the side effects of testosterone replacement therapy.

That aside, because PSA is essentially a tumor marker for prostate cancer, patients with a first-degree relative who has been diagnosed with prostate cancer and those with an elevated PSA level should proceed with caution and be monitored closely.

For men with a personal history of prostate cancer, treatment for Low T is considered contraindicated according to most sources.

It is important to note that testosterone replacement does not give you prostate cancer, but certainly elevated testosterone levels (even to the normal range) can cause an otherwise unnoticed prostate lesion to grow more aggressively.

Testosterone, in and of itself, is not a causative factor in the development of prostate cancer.

That myth has finally been debunked through countless studies over several years while more recent data now indicate that low serum testosterone levels are a potential predictor of high-risk prostate cancer.

The more interesting debate at this point is the potential consequence of increasing a mans testosterone level, even to a normal range, in the presence of an existing prostatic growth.

The findings of multiple studies over the years have ranged from testosterone appearing to be associated with promoting the transition of a common, low-grade lesion into one of a more aggressive nature, to testosterone actually contributing to cell death of the malignancy to no appreciable effect whatsoever.

Obviously the current data is inconclusive, however, it is becoming more and more apparent that as we ponder the safest recommendations, while peering through the lens of risk/benefit analysis, living with testosterone deficiency may indeed be the more risky endeavor.

The production of testosterone and sperm both are controlled by what is referred to as the Hypolthalamus-Pituitary-Gonadal Axis.

That is, the hypothalamus ( a portion of the forebrain responsible for the control of certain autonomic nervous system actions and pituitary gland activity) talks to the pituitary gland by mean of a chemical messenger (GnRH gonadotropin-releasing hormone).

The pituitary gland in turn will talk to the testicles (male gonads) also by means of different chemical messengers (LH luteinizing hormone and FSH follicular stimulating hormone).

Low T occurs when either this hormonal cycle fails to stimulate the testes to produce testosterone or more commonly when the testes themselves fail to respond to said stimulation.

When testosterone levels are normalized, either by natural means or through treatment of Low T, the brain reduces the stimulus to produce testosterone by secreting less GnRH.

Since this singular hormone controls both FSH and LH, the natural suppression of GnRH that occurs can reduce fertility.

Additionally, it is this same process that is responsible for the potential reduction in size and/or change in firmness of the testicles.

Other side effects of testosterone replacement therapy that are not part of normal functioning are increased red blood cell counts (erythrocytosis), potential decreases in good cholesterol or high-density lipoproteins (HDL), and increases in diastolic blood pressure (the lower of the two numbers reported in blood pressure readings).

The effects of high blood pressure are well known and the reasons for avoiding hypertension during TRT are no different from standard recommendations.

Increased number of red blood cells on the other hand, can lead to significant risk if not managed appropriately.

Think of red blood cells (RBCs) as the solid portion of the solution that is whole blood, and your hematocrit (HCT) the percentage of blood volume made up of RBCs.

If you add more solid to any solution without proportionately increasing the volume of the liquid it is suspended within, the result is a thicker solution.

Thickening of the blood then, is the end result of an increase in the number of RBCs.

Hematocrit values greater than 54.0% increase a patients risk factors for abnormal clotting, spleen enlargement, heart failure and other serious conditions.

If erythrocytosis does occur, it is typically rather easy to address. However if its assessment is overlooked, as is far too often the case, it can lead to potentially serious problems.

Certain side effects of testosterone replacement therapy are preparation specific. Gels, creams, and other topical agents can cause skin irritation and secondary exposure to women and children who come into contact with the medication via direct transfer.

Some untoward consequences of use of topicals is the wonderful odor (or fragrance, to steal Big Pharmas term) that is associated with it.

Failure rates are much, much higher for this type of medication owing to the inability of 30-40% of men to even absorb enough to improve their testosterone levels.

Virtually every medical treatment can cause adverse reactions. All things considered, the side effects of testosterone replacement therapy are quite manageable.

We know what to look for and how to intervene. With careful monitoring, it is entirely possible to treat and/or prevent significant problems these side effects may pose.

Ultimately it comes down to balance. Can we approach Low T treatment in such a way that allows for minimization of side effects while allowing for optimization of results? Absolutely!

What is necessary to achieve this is having providers who are open and honest about the benefits AND the risks associated with TRT. If you have questions, we would love the opportunity to talk with you and answer them.

Please Contact Us to schedule a no-obligation consultation in our clinic. If you are suffering from Low T and are ready to improve the quality of your life but are concerned about the side effects of testosterone replacement therapy (TRT), the dedicated providers at Testosterone Centers of Texas are ready to help you.

See original here:
Side Effects of Testosterone Replacement Therapy (TRT)

Recommendation and review posted by Alexandra Lee Anderson

Testosterone Replacement Therapy Seattle WA – Dr Kate Kass

If youre like most men, you ignore health issues large and small, toughing it out until your body feels out of whack or accepting a slow decline in mood, motivation, and libido that you just chalk up to normal aging.

Perhaps you visit a primary care physician once a year who says everythings fine, but you have a growing belly, no energy, and your erectile function isnt what it used to be. Maybe you have an expanding medicine cabinet of pharmaceuticals that are causing unwanted side effects. Sound familiar?

Thats a shame because you dont have to live with subpar health. There are many ways to optimize your health at any age and restore the youthful energy and vigor you used to depend on. It could be your thyroid, leaky gut, side effects to medications, or elevated cortisol levels that are laying you low.

And it could be low testosterone. Low testosterone affects your sexual function, but it can also be the root cause of fatigue, weight gain, sleep apnea, and a whole laundry list of less-than-desirable symptoms. But the good news is, if you seek out the right help, you can prevent disease and regain a sense of wellness and vitality.

Thats where Dr. Kate Kass comes in. A licensed primary care physician, Dr. Kass specializes in functional medicine, age management, and mens sexual wellness.

She seeks out cutting-edge therapies, tests, and protocols from the worlds of conventional and functional medicine to diagnose the root problem and create an effective treatment plan customized to your specific symptoms and concerns. (Read more about Dr. Kasss philosophy)

Starting around a mans mid-30s, total testosterone declines at a rate of 10 percent each decade and more than 40 percent of males 40 and above have a testosterone deficiency.

It is during this time that men experience andropause, the male counterpart to menopause. Testosterone is tricky. It doesnt just affect sexual performance. In fact, you actually may have satisfactory erectile function but still test below optimal levels for testosterone.

Why does this matter? Because testosterone is a factor in all sorts of bodily functions. When your levels are optimal, testosterone protects against cardiovascular disease, reduces blood sugar, improves lean muscle mass, increases bone density, decreases cholesterol, and increases libido and sexual performance.

Its a powerful tool in preventing disease and improving your quality of life. When you have low testosterone, however, you may experience the following symptoms:

If any of these symptoms strike a chord, you may have a testosterone decline, and you should seek out an expert for a comprehensive evaluation.

As a specialist in testosterone replacement therapy in Seattle, Dr. Kass believes that you dont have to resign yourself to unwanted symptoms of aging.

In her practice, she has helped male patients regain vitality and their libido, manage their weight, and improve their mood – all while slowing the aging process and preventing disease.

Dr. Kass has extensive training and experience in all the safe, effective methods of testosterone delivery, and is one of the few practitioners trained to offer testosterone via pellet implantation.

Dr. Kass fine tunes your treatment, and manages the various adjunctive hormones that also play a role in optimizing testosterone function and your overall health.

Read more here:
Testosterone Replacement Therapy Seattle WA – Dr Kate Kass

Recommendation and review posted by Alexandra Lee Anderson

Erectile Dysfunction and Testosterone Replacement Therapy

Testosterone is a hormone produced by the testicles and is responsible for the proper development of male sexual characteristics. Testosterone is also important for maintaining muscle bulk, adequate levels of red blood cells, bone growth, a sense of well-being, and sexual function.

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.

As a man ages, the amount of testosterone in his body naturally gradually declines. This decline starts after age 30 and continues throughout life. Some causes of low testosterone levels are due to:

Without adequate testosterone, a man may lose his sex drive, experience erectile dysfunction, feel depressed, have a decreased sense of well-being, and have difficulty concentrating.

Low testosterone can cause the following physical changes:

The only accurate way to detect the condition is to have your doctor measure the amount of testosterone in your blood. Because testosterone levels fluctuate throughout the day, several measurements will need to be taken to detect a deficiency. Doctors prefer, if possible, to test levels early in the morning, when testosterone levels are highest.

Note: Testosterone should only be used by men who have clinical signs and symptoms AND medically documented low testosterone levels.

Testosterone deficiency can be treated by:

Each of these options provides adequate levels of hormone replacement; however, they all have different advantages and disadvantages. Talk to your doctor to see which approach is right for you.

Men who have prostate cancer or breast cancer should not take testosterone replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure. All men considering testosterone replacement therapy should undergo a thorough prostate cancer screening — a rectal exam and PSA test — prior to starting this therapy.

In general, testosterone replacement therapy is safe. It is associated with some side effects, including:

Laboratory abnormalities that can occur with hormone replacement include:

If you are taking hormone replacement therapy, regular follow-up appointments with your doctor are important.

Like any other medication, directions for administering testosterone should be followed exactly as your doctor orders. If you are unsure or have any questions about testosterone replacement therapy, ask your doctor.

SOURCE:

Get-Back-On-Track.com.

The Hormone Foundation.

News release, FDA.

Original post:
Erectile Dysfunction and Testosterone Replacement Therapy

Recommendation and review posted by Alexandra Lee Anderson

Testosterone Replacement Therapy Vivacity Clinic of Las …

The medical community agrees that testosterone begins to decline gradually in most men by the time they reach the age of 30. If left unchecked, testosterone levels will continue to decline as you age, meaning that the average 50-year-old will have far less testosterone than the average 35-year-old, even though individuals are in a state of testosterone decline.

The effects of diminishing testosterone should be hardly noticeable for most men in their 30s. Once you hit 50, however, the effects may truly start to set in. Your sex drive may be reduced, you may have difficulty getting or maintaining an erection, your overall mood and energy may drop, and you may feel symptoms of irritability and even depression. Fortunately, the availability of testosterone replacement therapies for men over 50 means that you can break this cycle and regain at least some of the vitality you possessed as a young man.

VCLV Testosterone Replacement Therapy (TRT)offers physician prescribed and medically supervised Testosterone Therapy programs helping patients enter a cost effective and comprehensive Low Testosterone Treatment program designed to treat adult men over the age of 35 suffering from symptoms and problems associated with Low-T,hypogonadism and andropause also known as “male menopause”.

Testosterone Replacement Therapy (TRT) with injectable testosterone, testosterone cream or gel can help men with low testosterone levels. Testosterone treatment is carefully formulated to help alleviate symptoms due to male menopause – Low T.

Treat low testosterone symptoms: loss of energy; low sex drive; erectile dysfunction; loss of muscle tone; irritability; depression; insomnia, feeling tired all the time bordering on fatigue; loss of focus and drive.

See the original post here:
Testosterone Replacement Therapy Vivacity Clinic of Las …

Recommendation and review posted by Alexandra Lee Anderson