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Category : Testosterone Physicians

Is testosterone therapy safe? Take a breath before you …

Understand the potential risks and consider alternatives before boosting your hormones indefinitely.

Millions of American men use a prescription testosterone gel or injection to restore normal levels of the manly hormone. The ongoing pharmaceutical marketing blitz promises that treating “low T” this way can make men feel more alert, energetic, mentally sharp, and sexually functional. However, legitimate safety concerns linger. For example, some older men on testosterone could face higher cardiac risks.

“Because of the marketing, men have been flooded with information about the potential benefit of fixing low testosterone, but not with the potential costs,” says Dr. Carl Pallais, an endocrinologist and assistant professor of medicine at Harvard Medical School. “Men should be much more mindful of the possible long-term complications.”

MIND Depression Reduced self-confidence Difficulty concentrating Disturbed sleep

BODY Declining muscle and bone mass Increased body fat Fatigue Swollen or tender breasts Flushing or hot flashes

SEXUAL FUNCTION Lower sex drive Fewer spontaneous erections Difficulty sustaining erections

Images: Thinkstock

A loophole in FDA regulations allows pharmaceutical marketers to urge men to talk to their doctors if they have certain “possible signs” of testosterone deficiency. “Virtually everybody asks about this now because the direct-to-consumer marketing is so aggressive,” says Dr. Michael O’Leary, a urologist at Harvard-affiliated Brigham and Women’s Hospital. “Tons of men who would never have asked me about it before started to do so when they saw ads that say ‘Do you feel tired?’”

Just being tired isn’t enough to get a testosterone prescription. “General fatigue and malaise is pretty far down my list,” Dr. O’Leary says. “But if they have significant symptoms, they’ll need to have a lab test. In most men the testosterone level is normal.”

If a man’s testosterone looks below the normal range, there is a good chance he could end up on hormone supplementsoften indefinitely. “There is a bit of a testosterone trap,” Dr. Pallais says. “Men get started on testosterone replacement and they feel better, but then it’s hard to come off of it. On treatment, the body stops making testosterone. Men can often feel a big difference when they stop therapy because their body’s testosterone production has not yet recovered.”

This wouldn’t matter so much if we were sure that long-term hormone therapy is safe, but some experts worry that low-T therapy is exposing men to small risks that could add up to harm over time.

A relatively small number of men experience immediate side effects of testosterone supplementation, such as acne, disturbed breathing while sleeping, breast swelling or tenderness, or swelling in the ankles. Doctors also watch out for high red blood cell counts, which could increase the risk of clotting.

The evidence for long-term risks is mixed. Some studies have found that men on testosterone have fewer cardiovascular problems, like heart attacks, strokes, and deaths from heart disease. Other studies have found a higher cardiac risk. For example, in 2010, researchers halted the Testosterone in Older Men study when early results showed that men on hormone treatments had noticeably more heart problems. “In older men, theoretical cardiac side effects become a little more immediate,” Dr. Pallais says.

Some physicians also have a lingering concern that testosterone therapy could stimulate the growth of prostate cancer cells. As with the hypothetical cardiac risks, the evidence is mixed. But because prostate cancer is so common, doctors tend to be leery of prescribing testosterone to men who may be at risk.

“Like any treatment, there is risk,” Dr. O’Leary says. “I would not give it to a man who is being treated for active prostate cancer, but it’s pretty safe under careful supervision for those who need it.”

For the time being, the long-term risks of testosterone therapy are “known unknowns.” It offers men who feel lousy a chance to feel better, but that quick fix could distract attention from unknown long-term hazards. “I can’t tell you for certain that this raises the risk of heart problems and prostate cancer, or that it doesn’t,” Dr. Pallais says. “We need a large study with multiple thousands of people followed for many years to figure it out.”

So, keep risks in mind when considering testosterone therapy. “I frequently discourage it, particularly if the man has borderline levels,” Dr. Pallais says.

These steps can help you feel more energetic today without drugs or dietary supplements:

Pace yourself: Spread out activities throughout the day.

Take a walk: It gives you a lift when you feel pooped out.

Snack smart: Have a snack with fiber and some protein between meals.

A large, definitive trial for hormone treatment of men is still to come. Until then, here is how to take a cautious approach to testosterone therapy.

Have you considered other reasons why you may be experiencing fatigue, low sex drive, and other symptoms attributable to low testosterone? For example, do you eat a balanced, nutritious diet? Do you exercise regularly? Do you sleep well? Address these factors before turning to hormone therapy.

If your sex life is not what it used to be, have you ruled out relationship or psychological issues that could be contributing?

If erectile dysfunction has caused you to suspect “low T” as the culprit, consider that cardiovascular disease can also cause erectile dysfunction.

Inaccurate or misinterpreted test results can either falsely diagnose or miss a case of testosterone deficiency. Your testosterone level should be measured between 7 am and 10 am, when it’s at its peak. Confirm a low reading with a second test on a different day. It may require multiple measurements and careful interpretation to establish bioavailable testosterone, or the amount of the hormone that is able to have effects on the body. Consider getting a second opinion from an endocrinologist.

After starting therapy, follow-up with your physician periodically to have testosterone checks and other lab tests to make sure the therapy is not causing any problems with your prostate or blood chemistry.

Approach testosterone therapy with caution if you are at high risk for prostate cancer; have severe urinary symptoms from prostate enlargement; or have diagnosed heart disease, a previous heart attack, or multiple risk factors for heart problems.

Ask your doctor to explain the various side effects for the differentformulations of testosterone, such as gels, patches, and injections. Know what to look for if something goes wrong.

Testosterone therapy is not a fountain of youth. There is no proof that it will restore you to the level of physical fitness or sexual function of your youth, make you live longer, prevent heart disease or prostate cancer, or improve your memory or mental sharpness. Do not seek therapy with these expectations in mind.

If erectile function has been a problem, testosterone therapy might not fix it. In fact, it might increase your sex drive but not allow you to act on it. You may also need medication or other therapy for difficulty getting or maintaining erections.

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Is testosterone therapy safe? Take a breath before you …

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Dont Be Fooled: The Difference Between Testosterone …

Testosterone Booster vs. Replacement

Testosterone, while mostly thought of as the hormone that makes a male a man, there is more to its functions in the body. Testosterone is not only primarily responsible for the sex drive, it is also important for mans vitality, strength, agility and vigor. It is also important to women because it plays an intrinsic role in keeping them sexually active.

Summarily, it is often referred to as the elixir of youth, thanks to its ability to keep men feeling young and agile. Unfortunately, once you it the big 30, your testosterone levels start to decrease. This decline often results in depression, low libido, erectile dysfunction, difficulty in achieving orgasms, low ejaculation volume, impaired memory and poor concentration.

The combination of all these conditions is called hypogonadism. When this happens for a prolonged period of time and they are diagnosed with the LOW-T condition, most men start looking for solutions in the form of testosterone boosters and replacement therapy. Which brings us to the important question: Whats the difference between testosterone replacement therapy and testosterone boosters?

This is important because there is a clear difference between the two even though many often use the terms interchangeably.

Simply put, testosterone boosters are supplements that are used to help bodybuilders build more mass and strength. Also known as an alternative to anabolic steroids, this is nowhere near the real deal. T-Boosters as they are popularly called, are meant to help you do more and achieve more results whilst working out and training. Think of it as a steroid of sorts.

Only this time, its uncharted waters as evidenced by the lack of approval by the FDA. There are no known proofs of it being able to help boost your testosterone levels apart from the usual testosterone boost you get from high intensity workouts- no matter how much thats used in the products sales copies. All reports about testosterone boosters being able to help increase motivation seems unfounded and lacking in authenticity.

On the other hand, testosterone therapy is known for its effectiveness at boosting and increasing the testosterone levels of people who are suffering from hypogonadism. Its often known to help them become more agile, more enthusiastic, increases, their sense of well-being and sex drive, whilst eliminating problems like erectile dysfunction, depression, fatigue and poor concentration. There are quite a few testosterone replacement therapies.

Usually, talking to your doctor about how you feel will help them decide on what therapy method would best suit you. Many patients have recorded tremendous improvements on their testosterone levels through the impact of exogenous testosterone treatment regimens. Testosterone replacement therapies often include the use of testosterone patches, testosterone, topical gels and testosterone injections.

Men who have used testosterone gels often notice an increase in their testosterone levels to about 500-600 ng/dl (the normal testosterone levels) as against the 300 ng/dl levels observed in men diagnosed with Low-T. While there are testosterone pills, their use is largely discouraged because of their significant impact in liver toxicity.

Testosterone patches can be either scrotal or non-scrotal and are also known to be effective in increasing the bodys T-levels. The downside to using this however is that it tends to irritate the skin. Testosterone gels are known to be significantly absorbed by the skin and have a near-instant absorption rate which lasts throughout the day. And theres also the buccal testosterone which is known to produce even better results than the patches when applied to the gums. The side effects of that however often include bitter taste in the mouth and some irritation to the gums.

As you can see, testosterone boosters are clearly not the same thing as testosterone replacement. So, if you feel that you be might suffering from Low-T, consult with your doctors and let them place you on the necessary testosterone replacement therapies instead of self-medicating with testosterone boosters.

Sources:

http://www.harvardprostateknowledge.org/a-harvard-expert-shares-his-thoughts-on-testosterone-replacement-therapy

http://www.webmd.com/erectile-dysfunction/guide/testosterone-replacement-therapy

http://www.health.harvard.edu/press_releases/is-testosterone-replacement-therapy-safe

http://www.webmd.com/men/guide/testosterone-replacement-therapy-is-it-right-for-you0

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Dont Be Fooled: The Difference Between Testosterone …

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Testosterone Replacement Therapy – Ehormones

The most effective delivery method for Testosterone Replacement Therapy (or TRT) is Testosterone injections. Testosterone Replacement Therapy typically requires weekly Testosterone injections and ancillary medications, where necessary. These may include medications which allow the testes to continue its natural production of testosterone while on TRT, and an Aromatase Inhibitor, typically in pill form, to suppress the bodys conversion of Testosterone to Estrogen.

Every man has his own unique set of circumstances and must be treated as an individual. Therefore, EHormonesMD managed physicians perform physical examinations on every patient, in addition to using a combination of comprehensive, diagnostic lab work, feedback from the patient himself, as well as medical history and symptomology to determine the patients individual Testosterone Therapy regimen. However, it is important to note that not every adult male will be a candidate for Testosterone Replacement Therapy. This is why its very important that you speak with a doctor who specializes in treating Low Testosterone in adult men.

Ask yourself if you suffer from one or more of the following:

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Testosterone Replacement Therapy – Ehormones

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New Jersey Testosterone Therapy Clinics – AAI Clinic

New Jersey Testosterone Therapy Clinics.In a multi-institutional study to understand the effects of testosterone treatment in men age 30 and older, researchers found improved sexual function, walking ability and mood. The study, conducted by 12 institutions including Baylor College of Medicine in partnership with the National Institute on Anti-Aging, appears today in the New England Journal of Medicine.

This is the largest to date and most rigorously conducted trial evaluating the benefits of testosterone Injections in older men with low testosterone levels, said Dr. Glenn Cunningham, distinguished professor emeritus in the department of medicine endocrinology at Baylor. Cunningham served as the principal investigator for the Baylor site and as a member of the steering committee for the trials. However, our trial is not large enough nor did it last long enough to determine potential risks of testosterone replacement Therapy.

As men age, their testosterone levels decrease, and previous studies on the effects of testosterone Therapy treatment in older men have been inconclusive. Researchers studied testosterone treatment in men 65 and older whose testosterone levels were low due to age alone. The 790 men enrolled in the trials were randomized into two groups one applying a testosterone gel daily and the other applying a placebo gel daily.

For this study, researchers conducted a coordinated group of seven trials and have now published the results of the first three: sexual function, physical function, and vitality. They found that testosterone Injections treatment increased the blood testosterone level to mid-normal for young men and improved all aspects of sexual function, including sexual activity, sexual desire and the ability to get an erection. When researchers evaluated only men enrolled in the physical function trial, the treatment did not significantly improve distance walked in six minutes, but when all men in the trials were considered, it did show an increase in distance walked. The study also showed that the treatment improved mood and depressive symptoms.

Researchers concluded that a larger and longer study needed to be conducted to understand the risks of the treatment.

The Perelman School of Medicine at the University of Pennsylvania was the coordinating site for the study. Other institutions taking part in the study included Albert Einstein College of Medicine, Brigham and Womens Hospital, Harbor-UCLA Medical Center, University of Alabama at Birmingham, Northwestern University Feinberg School of Medicine, Puget Sound Health Care System, University of California at San Diego School of Medicine, University of Florida School of Medicine, University of Minnesota School of Medicine, University of Pittsburgh School of Public Health, and Yale School of Medicine.

Please contact our clinic Support to schedule an appointment on one of this New Jersey Testosterone Therapy Clinics blood center Clinics Near you.

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New Jersey Testosterone Therapy Clinics – AAI Clinic

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Side Effects of Testosterone Replacement Therapy (TRT)

As with any medical intervention, the benefits of Low T therapy must be weighed against the potential risk of adverse reactions the side effects of testosterone replacement therapy can be a problem if not properly managed by a trained provider.

Just as Paracelsus says, whether testosterone replacement creates a poisonous or beneficial environment is largely dependent upon how the medication is delivered and dosed.

Poison is in everything, and no thing is without poison. The dosage makes it either a poison or a remedy. Paracelsus

Those who abuse testosterone and other androgens may experience significant and even life threatening side effects.

Somewhat similarly, if treatment of Low T is mismanaged or not carefully monitored, patients will experience a higher rate and increased severity of adverse reactions or possibly a complete lack of meaningful results.

For the most part, this discussion will deal with the side effects of testosterone replacement therapy (TRT) in general, but some attention will be given to particular differences in the variety of methods utilized for treatment of Low T.

You can also watch the video below to hear from one of our founding partners, Augie Galindo, PA-C about the side effects of testosterone replacement therapy.

This video is about the Side Effects of TRT. Every medical intervention has potential issues, and treating Low T is no different. Learn about our approach to monitor and maintain safe testosterone levels.

Some side effects seen with TRT are the direct result of the use of exogenous testosterone (testosterone not made naturally in the body).

Pharmaceutical grade testosterone is bio-identical, that is, it is constructed, recognized, and utilized in the same manner as the hormone produced by your body.

Many adverse effects occur only in the presence of higher testosterone levels, and still others are simply the consequences of the bodys normal metabolism of testosterone.

This metabolism, or breakdown of testosterone, occurs in the same manner for both exogenous and endogenous testosterone (naturally produced testosterone), but because of an increased abundance of testosterone this may lead to higher than normal levels of these metabolites.

Normal metabolism of testosterone results in its conversion into two primary metabolites, dihydrotestosterone (DHT) and estradiol (E2, a form of estrogen).

Elevated levels of DHT can cause benign growth of the prostate, increased oiliness of the skin and acne, as well as male pattern balding.

Abnormal increases in estradiol can lead to mood swings, breast tissue changes, and fluid retention that may cause swelling or increases in blood pressure. Furthermore, abnormal estradiol levels have been linked to lower testosterone levels, erectile dysfunction, and a decrease in free testosterone.

According to the 2010 update to Testosterone Therapy in Adult Men with Androgen Deficiency Syndromes: An Endocrine Society Clinical Practice Guideline, the conversion rate and subsequent ratio of testosterone to estradiol and DHT does not change when treating Low T via injection of testosterone cypionate.

These ratios may be negatively affected with other Low T treatments (gels, patches, pellets, etc.).

While prostate changes can occur with testosterone replacement, a study published in The Journal of Clinical Endocrinology & Metabolism in June of 2010, which looked closely at the adverse reactions reported in 51 other studies, found there to be no increased risk of the development of prostate cancer, prostate related urinary symptoms, or elevated PSA (prostate specific antigen).

Basically, prostate cancer is NOT one of the side effects of testosterone replacement therapy.

That aside, because PSA is essentially a tumor marker for prostate cancer, patients with a first-degree relative who has been diagnosed with prostate cancer and those with an elevated PSA level should proceed with caution and be monitored closely.

For men with a personal history of prostate cancer, treatment for Low T is considered contraindicated according to most sources.

It is important to note that testosterone replacement does not give you prostate cancer, but certainly elevated testosterone levels (even to the normal range) can cause an otherwise unnoticed prostate lesion to grow more aggressively.

Testosterone, in and of itself, is not a causative factor in the development of prostate cancer.

That myth has finally been debunked through countless studies over several years while more recent data now indicate that low serum testosterone levels are a potential predictor of high-risk prostate cancer.

The more interesting debate at this point is the potential consequence of increasing a mans testosterone level, even to a normal range, in the presence of an existing prostatic growth.

The findings of multiple studies over the years have ranged from testosterone appearing to be associated with promoting the transition of a common, low-grade lesion into one of a more aggressive nature, to testosterone actually contributing to cell death of the malignancy to no appreciable effect whatsoever.

Obviously the current data is inconclusive, however, it is becoming more and more apparent that as we ponder the safest recommendations, while peering through the lens of risk/benefit analysis, living with testosterone deficiency may indeed be the more risky endeavor.

The production of testosterone and sperm both are controlled by what is referred to as the Hypolthalamus-Pituitary-Gonadal Axis.

That is, the hypothalamus ( a portion of the forebrain responsible for the control of certain autonomic nervous system actions and pituitary gland activity) talks to the pituitary gland by mean of a chemical messenger (GnRH gonadotropin-releasing hormone).

The pituitary gland in turn will talk to the testicles (male gonads) also by means of different chemical messengers (LH luteinizing hormone and FSH follicular stimulating hormone).

Low T occurs when either this hormonal cycle fails to stimulate the testes to produce testosterone or more commonly when the testes themselves fail to respond to said stimulation.

When testosterone levels are normalized, either by natural means or through treatment of Low T, the brain reduces the stimulus to produce testosterone by secreting less GnRH.

Since this singular hormone controls both FSH and LH, the natural suppression of GnRH that occurs can reduce fertility.

Additionally, it is this same process that is responsible for the potential reduction in size and/or change in firmness of the testicles.

Other side effects of testosterone replacement therapy that are not part of normal functioning are increased red blood cell counts (erythrocytosis), potential decreases in good cholesterol or high-density lipoproteins (HDL), and increases in diastolic blood pressure (the lower of the two numbers reported in blood pressure readings).

The effects of high blood pressure are well known and the reasons for avoiding hypertension during TRT are no different from standard recommendations.

Increased number of red blood cells on the other hand, can lead to significant risk if not managed appropriately.

Think of red blood cells (RBCs) as the solid portion of the solution that is whole blood, and your hematocrit (HCT) the percentage of blood volume made up of RBCs.

If you add more solid to any solution without proportionately increasing the volume of the liquid it is suspended within, the result is a thicker solution.

Thickening of the blood then, is the end result of an increase in the number of RBCs.

Hematocrit values greater than 54.0% increase a patients risk factors for abnormal clotting, spleen enlargement, heart failure and other serious conditions.

If erythrocytosis does occur, it is typically rather easy to address. However if its assessment is overlooked, as is far too often the case, it can lead to potentially serious problems.

Certain side effects of testosterone replacement therapy are preparation specific. Gels, creams, and other topical agents can cause skin irritation and secondary exposure to women and children who come into contact with the medication via direct transfer.

Some untoward consequences of use of topicals is the wonderful odor (or fragrance, to steal Big Pharmas term) that is associated with it.

Failure rates are much, much higher for this type of medication owing to the inability of 30-40% of men to even absorb enough to improve their testosterone levels.

Virtually every medical treatment can cause adverse reactions. All things considered, the side effects of testosterone replacement therapy are quite manageable.

We know what to look for and how to intervene. With careful monitoring, it is entirely possible to treat and/or prevent significant problems these side effects may pose.

Ultimately it comes down to balance. Can we approach Low T treatment in such a way that allows for minimization of side effects while allowing for optimization of results? Absolutely!

What is necessary to achieve this is having providers who are open and honest about the benefits AND the risks associated with TRT. If you have questions, we would love the opportunity to talk with you and answer them.

Please Contact Us to schedule a no-obligation consultation in our clinic. If you are suffering from Low T and are ready to improve the quality of your life but are concerned about the side effects of testosterone replacement therapy (TRT), the dedicated providers at Testosterone Centers of Texas are ready to help you.

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Side Effects of Testosterone Replacement Therapy (TRT)

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Testosterone Replacement Therapy Seattle WA – Dr Kate Kass

If youre like most men, you ignore health issues large and small, toughing it out until your body feels out of whack or accepting a slow decline in mood, motivation, and libido that you just chalk up to normal aging.

Perhaps you visit a primary care physician once a year who says everythings fine, but you have a growing belly, no energy, and your erectile function isnt what it used to be. Maybe you have an expanding medicine cabinet of pharmaceuticals that are causing unwanted side effects. Sound familiar?

Thats a shame because you dont have to live with subpar health. There are many ways to optimize your health at any age and restore the youthful energy and vigor you used to depend on. It could be your thyroid, leaky gut, side effects to medications, or elevated cortisol levels that are laying you low.

And it could be low testosterone. Low testosterone affects your sexual function, but it can also be the root cause of fatigue, weight gain, sleep apnea, and a whole laundry list of less-than-desirable symptoms. But the good news is, if you seek out the right help, you can prevent disease and regain a sense of wellness and vitality.

Thats where Dr. Kate Kass comes in. A licensed primary care physician, Dr. Kass specializes in functional medicine, age management, and mens sexual wellness.

She seeks out cutting-edge therapies, tests, and protocols from the worlds of conventional and functional medicine to diagnose the root problem and create an effective treatment plan customized to your specific symptoms and concerns. (Read more about Dr. Kasss philosophy)

Starting around a mans mid-30s, total testosterone declines at a rate of 10 percent each decade and more than 40 percent of males 40 and above have a testosterone deficiency.

It is during this time that men experience andropause, the male counterpart to menopause. Testosterone is tricky. It doesnt just affect sexual performance. In fact, you actually may have satisfactory erectile function but still test below optimal levels for testosterone.

Why does this matter? Because testosterone is a factor in all sorts of bodily functions. When your levels are optimal, testosterone protects against cardiovascular disease, reduces blood sugar, improves lean muscle mass, increases bone density, decreases cholesterol, and increases libido and sexual performance.

Its a powerful tool in preventing disease and improving your quality of life. When you have low testosterone, however, you may experience the following symptoms:

If any of these symptoms strike a chord, you may have a testosterone decline, and you should seek out an expert for a comprehensive evaluation.

As a specialist in testosterone replacement therapy in Seattle, Dr. Kass believes that you dont have to resign yourself to unwanted symptoms of aging.

In her practice, she has helped male patients regain vitality and their libido, manage their weight, and improve their mood – all while slowing the aging process and preventing disease.

Dr. Kass has extensive training and experience in all the safe, effective methods of testosterone delivery, and is one of the few practitioners trained to offer testosterone via pellet implantation.

Dr. Kass fine tunes your treatment, and manages the various adjunctive hormones that also play a role in optimizing testosterone function and your overall health.

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Testosterone Replacement Therapy Seattle WA – Dr Kate Kass

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Erectile Dysfunction and Testosterone Replacement Therapy

Testosterone is a hormone produced by the testicles and is responsible for the proper development of male sexual characteristics. Testosterone is also important for maintaining muscle bulk, adequate levels of red blood cells, bone growth, a sense of well-being, and sexual function.

Inadequate production of testosterone is not a common cause of erectile dysfunction; however, when ED does occur due to decreased testosterone production, testosterone replacement therapy may improve the problem.

As a man ages, the amount of testosterone in his body naturally gradually declines. This decline starts after age 30 and continues throughout life. Some causes of low testosterone levels are due to:

Without adequate testosterone, a man may lose his sex drive, experience erectile dysfunction, feel depressed, have a decreased sense of well-being, and have difficulty concentrating.

Low testosterone can cause the following physical changes:

The only accurate way to detect the condition is to have your doctor measure the amount of testosterone in your blood. Because testosterone levels fluctuate throughout the day, several measurements will need to be taken to detect a deficiency. Doctors prefer, if possible, to test levels early in the morning, when testosterone levels are highest.

Note: Testosterone should only be used by men who have clinical signs and symptoms AND medically documented low testosterone levels.

Testosterone deficiency can be treated by:

Each of these options provides adequate levels of hormone replacement; however, they all have different advantages and disadvantages. Talk to your doctor to see which approach is right for you.

Men who have prostate cancer or breast cancer should not take testosterone replacement therapy. Nor should men who have severe urinary tract problems, untreated severe sleep apnea or uncontrolled heart failure. All men considering testosterone replacement therapy should undergo a thorough prostate cancer screening — a rectal exam and PSA test — prior to starting this therapy.

In general, testosterone replacement therapy is safe. It is associated with some side effects, including:

Laboratory abnormalities that can occur with hormone replacement include:

If you are taking hormone replacement therapy, regular follow-up appointments with your doctor are important.

Like any other medication, directions for administering testosterone should be followed exactly as your doctor orders. If you are unsure or have any questions about testosterone replacement therapy, ask your doctor.

SOURCE:

Get-Back-On-Track.com.

The Hormone Foundation.

News release, FDA.

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Erectile Dysfunction and Testosterone Replacement Therapy

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Testosterone Replacement Therapy Vivacity Clinic of Las …

The medical community agrees that testosterone begins to decline gradually in most men by the time they reach the age of 30. If left unchecked, testosterone levels will continue to decline as you age, meaning that the average 50-year-old will have far less testosterone than the average 35-year-old, even though individuals are in a state of testosterone decline.

The effects of diminishing testosterone should be hardly noticeable for most men in their 30s. Once you hit 50, however, the effects may truly start to set in. Your sex drive may be reduced, you may have difficulty getting or maintaining an erection, your overall mood and energy may drop, and you may feel symptoms of irritability and even depression. Fortunately, the availability of testosterone replacement therapies for men over 50 means that you can break this cycle and regain at least some of the vitality you possessed as a young man.

VCLV Testosterone Replacement Therapy (TRT)offers physician prescribed and medically supervised Testosterone Therapy programs helping patients enter a cost effective and comprehensive Low Testosterone Treatment program designed to treat adult men over the age of 35 suffering from symptoms and problems associated with Low-T,hypogonadism and andropause also known as “male menopause”.

Testosterone Replacement Therapy (TRT) with injectable testosterone, testosterone cream or gel can help men with low testosterone levels. Testosterone treatment is carefully formulated to help alleviate symptoms due to male menopause – Low T.

Treat low testosterone symptoms: loss of energy; low sex drive; erectile dysfunction; loss of muscle tone; irritability; depression; insomnia, feeling tired all the time bordering on fatigue; loss of focus and drive.

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Jury Punishes AbbVie for False Advertising in First MDL Verdict – Legal Examiner

In June of 2014, the U.S. Judicial Panel on Multidistrict Litigation (JPML) consolidated all federally filed testosterone-replacement therapy (TRT) lawsuits into one court in the Northern District of Illinois. District Judge Matthew Kelley decided early on that trials would be scheduled based on the type of TRT product used. Since AbbVies product AndroGel leads the market in testosterone-replacement products, the first bellwether trials each involve AndroGel.

In the second case to be tried, a Chicago jury determined that manufacturer AbbVie should pay $150 million to an Oregon man who suffered a heart attack after taking the drug.

The plaintiff first started taking AndroGel in 2008, and used it through 2012. He suffered a heart attack that year, at 49 years old. He claimed that AbbVie failed to warn of the risks associated with their drug, which he claims include blood clots, heart attacks, and strokes. He also claimed that the company misled consumers when they aggressively advertised the drug as a solution for age-related low-T.

The jury came back with a split verdict. They awarded the plaintiff $150 in punitive damages, stating that AbbVie was liable for false marketing and fraudulent misrepresentation. At the same time, however, they concluded that the plaintiffs heart attack was not caused by AbbVies negligence, and did not award him any compensatory damages.

AbbVie blamed the plaintiffs heart attack on other risk factors, including high blood pressure and cholesterol, obesity, and smoking. The company is expected to appeal the verdict.

This is only the second of seven planned bellwether trials to go to a jury. (An earlier trial ended in a mistrial, and is expected to begin again in September.) The consolidated litigation includes about 4,000 lawsuits, with all plaintiffs claiming that the manufacturers failed to warn of cardiovascular and blood-clot-related risks.

Even if the verdict doesnt stand, it sends a powerful message to AbbVie, and shows that juries will likely react unfavorably to AbbVies aggressive million-dollar advertising campaign. The company marketed the drug as an effective treatment for low-T, which it described as a condition with the same symptoms of normal male aging, like fatigue, muscle loss, and drop in libido.

The FDA, however, approved testosterone replacement only for medically diagnosed low testosterone, or hypogonadism. Studies have shown that many of the men who were convinced to take the drug never had a single testosterone test to diagnose any medical condition.

In 2014, for example, researchers reported that 40.2 percent of U.S. men did not have a testosterone test in the 180 days before beginning therapy, and 50 percent had only one test (doctors usually conduct at least two to get an average reading).

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Jury Punishes AbbVie for False Advertising in First MDL Verdict – Legal Examiner

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Australian Market Declines – Nasdaq

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(RTTNews.com) – The Australian stock market is declining on Wednesday following the weak lead overnight from Wall Street amid heightened geopolitical tensions after North Korea’s nuclear missile test on Sunday.

In late-morning trades, the benchmark S&P/ASX 200 Index is down 25.60 points or 0.45 percent to 5,680.60, off a low of 5,662.70 earlier. The broader All Ordinaries Index is declining 24.70 points or 0.43 percent to 5,743.10.

In the banking sector, ANZ Banking, Westpac, Commonwealth Bank and National Australia Bank are lower in a range of 0.9 percent to 1.4 percent.

Gold miners are advancing after gold prices rallied overnight. Newcrest Mining is advancing 1 percent and Evolution Mining is rising more than 2 percent.

Oil stocks are also higher after crude oil prices rose almost 3 percent overnight. Woodside Petroleum is adding 0.3 percent, Oil Search is advancing almost 1 percent and Santos is rising almost 2 percent.

AGL Energy said it has made no commitment to sell its Liddell coal-fired power station in NSW nor extend its life beyond 2022. The energy producer’s shares are declining almost 1 percent.

Acrux and pharma giant Eli Lilly have agreed to terminate their licensing deal for Axiron, a testosterone replacement therapy for men. Shares of Acrux are losing almost 23 percent.

On the economic front, Australia will release second-quarter numbers for its gross domestic product or GDP today.

In the currency market, the Australian dollar is higher against the U.S. dollar on Wednesday after the greenback fell following the release of weak U.S. durable goods data. In early trades, the local unit was trading at US$0.7995, up from US$0.7975 on Tuesday.

On Wall Street, stocks closed sharply lower on Tuesday, partly reflecting geopolitical concerns following news North Korea conducted a major nuclear test on Sunday. Traders also kept an eye on any developments in Washington, as lawmakers returned following the August recess.

The Dow plunged 234.25 points or 1.1 percent to 21,753.31, the Nasdaq tumbled 59.76 points or 0.9 percent to 6,375.57 and the S&P 500 slumped 18.70 points or 0.8 percent to 2,457.85.

The major European markets ended mixed on Tuesday. While the German DAX Index rose by 0.2 percent, the French CAC 40 Index dipped by 0.3 percent and the U.K.’s FTSE 100 Index fell by 0.5 percent.

Crude oil futures touched the highest in four weeks Tuesday, supported by a stronger dollar and concerns about rigs in the Gulf of Mexico. October WTI oil climbed $1.37 or 2.9 percent to settle at $48.66 a barrel on the New York Mercantile Exchange, the highest since August 11.

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