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Category : Anti-Aging Medicine

NAD IV Therapy: What Is This Trendy New Treatment & Is It Safe? –

First up: Any IV treatment also carries a small risk of bleeding and infection at the site where the needle is placed in the skin or getting too much fluid infused. IV infusions may be a common medical procedure, but they are still a medical procedure.

The second safety concern is where you are getting it, notes functional and integrative medicine practitioner Roxanna Namavar, M.D., board-certified psychiatrist and fellow in the American Academy of Anti-Aging Medicine, who uses it at her own practice."No matter what IV therapy you are getting, you want to make sure your practitioner knows where the ingredient is sourced, and how it is compounded. They should also tailor your infusion treatments to you: It shouldn't feel like you're picking things off a menu. Your practitioner should look at your lab work, symptoms, and goals and create a protocol that is specific to your needs."

This concern comes to light most notably with the large amounts of IV bars that have popped up lately, most without much regulation. The U.S. Federal Trade Commission recently took action against an IV drip bar for making unsupported health claims about their ability to treat serious illnesses such as cancer, multiple sclerosis, or congestive heart failure.

If done under the supervision of a responsible health care practitioner, however, Namavar says there are no significant safety concerns. She notes that some patients may be sensitive to IV NAD+ therapy, specifically, and experience discomfort such as warming of the chest and nausea. Wally Taylor, M.D., a functional medicine physician with Texas Integrative Medicine in Austin, Texas, notes similarly, "One of the things about NAD+ is that you can't infuse it too quickly without it being pretty uncomfortable." He says some of his patients, "say they feel like they're having symptoms of a heart attack, but when we look at their heart monitor, we don't see any evidence of that." He has found that breathing high-concentration oxygen during the infusion can reduce some of these side effects.

"Any time you're giving treatments intravenously, there could be problems of one sort or another," says Taylor. "So it's useful to have the direct oversight of a health care provider who has experience with NAD+." He says complications are more likely to arise in people with a chronic illness, but it's not impossible for healthy people to have a bad reaction.

Cost is another issue. A single IV NAD+ therapy ranges from several hundred dollars to $1,000 or more. You also have to factor in travel time to the clinic and the wait timeinfusions generally take two or more hours, and some people may need infusions several days in a row.

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NAD IV Therapy: What Is This Trendy New Treatment & Is It Safe? -

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The Best 40th Birthday Gifts, According to People Whove Reached (or Are About to Reach) 40 – New York Magazine

26 items in this article 6 items on sale!

Photo: Courtesy Universal Pictures

If you have a friend or a loved one about to turn 40, its likely that theyre currently taking stock of all theyve accomplished so far, while in the back of their mind gearing up for a whole new batch of anxieties. Its a birthday that can feel like a whirlwind, according to Christopher Choa, the director of cities and urban development at engineering firm AECOM. Youve mastered what you need to do for family and work, he told us, but youre anxious about having to deal with so many responsibilities on your own.

It would make sense, then, that such a transitional moment might call for a gift that seems a step up from the types of things you might give on any other birthday. According to Choa and the seven other cool people we spoke to all of whom have either marched over the hill or are about to turn 40 the best 40th-birthday gifts can be things to help one stay calm and relaxed or allow for a bit of self-pampering, items that let the recipient further indulge in a favorite pastime (like a nice cutting board for the home chef), or special pieces that the recipient could have for the next 40 years. (After all, by 40, youve learned to take care of your favorite things, says Scott Schuman, the founder of the Sartorialist.) Below, our eight cool people share 26 ideas from a sleek hairbrush to an anti-aging moisturizer to a statement pair of socks to the aforementioned cutting board that they say will help anyone entering their fifth decade do so in style.

Marie du Petit Thouars, the founder of cult-y candle and fragrance brand Maison Louie Marie, says that at 40, a person might find themselves with the time and space in their home to develop new skills. Thats precisely why she recommends gifting this pasta-making machine (that a professional pasta-maker has also recommended to us). Its something youd never buy yourself, du Petit Thouars says, but thats what makes it a wonderful addition to any foodie friends kitchen.

By the time youre 40, you might want even the most functional objects in your home to reflect your aesthetic and taste, according to du Petit Thouars, who says that this French press which weve also written about before manages to be both functional, unique, and calming. Its simple, the ceramic is unusual, and its elegant, she says all things that make it sound like a pretty great gift.

Fashion blogger and flight attendant Tenille Murphy told us that this Stagg kettle (that weve called the most stylish electric kettle there is) was a spot on gift from her husband. She adds: My first thought was how pretty, dare I say, sexy, it was, before noting that its as functional as it is stylish. As Murphy explains, the Stagg kettle has a digital readout enabling you to heat water to a precise temperature, which is one reason why she says it would make a great gift for any full-time tea drinker. And the kettles sleek, matte-black finish begs to be on prominent display in any kitchen, she says.

Another 40th-worthy kitchen tool, according to Murphy, is a high-end knife, like this Japanese chefs knife that she owns and loves. Japanese knives are lighter, typically hand honed, and, in my opinion, prettier, she told us. Murphy says if you really want to impress your recipient, you could gift the knife with one of Sur La Tables knife-skills classes. She took one and called it a game-changer that taught her how to best use her new knife for chopping, paring, slicing, and cutting like a professional chef. If youre interested in giving a knife but want to shop around, check out our everything guide to knives.

Should your recipient be all set with knives, Murphy says that an equally thoughtful gift would be a high-quality cutting board they can use with them. You cant just cut on any old surface once you have good knives, Murphy explains. According to her, these Epicurean cutting boards dont damage blades, stack nicely in drawers, come in a variety of sizes, and best of all, are very affordable.

And should your recipient be all set with knives and cutting boards, Murphy recommends giving them this tray that she calls a safe place to store their beauties without damaging their sharp edges. Because it can fit inside a drawer, the tray helps to keep countertops clutter free, and unlike wood blocks that sit on counters, it doesnt matter which slot I lay my knives in.

Fancy olive oil is another thing someone rarely buys for themselves, but that most home cooks really appreciate. While weve written about many chef-approved olive oils, this high-quality bottle du Petit Thouars recommends is new to us. She found it at a small store near her home in L.A. that she says only sells the most amazing Italian goods. For more olive oils to choose from, check out our list of the best olive oils, according to chefs.

Du Petit Thouars adds that shed love anyone who gave her this healthy dark chocolate. Its from Belgium, where I grew up, and I always come back to it. If you choose to go the dark-chocolate route, consider gifting this with writer and cook Skye McAlpines treasured dark-chocolate tip that she shared with our friends at Strategist UK: My secret obsession is four chunks of chocolate on hot toast with a sprinkling of salt and a drizzle of olive oil. I cant tell you how unbelievably good it is.

Im turning 40 in April, and with every passing year, my interest in motivating myself to go out at night has dwindled, Brett Heyman, the founder of accessories brands Edie Parker and Flower by Edie Parker, told us. However, my interest in having friends over for a cocktail and a truffle goat cheese or soft ewes milk on a cracker has skyrocketed. Thats why she recommends sending your new 40-year-old a cheese-of-the-monthmembership, like this one from Murrays Cheese, which will ensure them a delivery of the latest and greatest fromages for as many months or years as you choose. In Heymans words, its the most thoughtful way to say I see you, and I love you.

For the big 4-0, I dont want to give a practical gift that will be swept up in the tide of daily life and forgotten, says writer Amanda Fortini, but rather a beautiful, not-so-useful object that you will treasure and would probably never buy for yourself. Thats why she chose to give her husband this set of tarot cards from Taschen, which is based on Salvador Dals cards commissioned for the James Bond film Live and Let Die. In addition to being a full deck you can use for a reading, the cards, which Fortini says are equal parts trippy and spooky and come in a purple felt box, would make for an eye-catching coffee-table accessory.

Perhaps your recipient is a sucker for the latest Scandinavian dramas or lives for MSNBCs nightly lineup? If so, you might want to get them something theyll really, really use. Yes, $1,500 can seem like an insane amount of money to spend on a TV, says Strategist senior editor Peter Martin, but OLED, the LED alternative thats been top of the television market in recent years, really does feel like 3-D. Martin says that this LG television specifically is worthy of the big spend you might be planning if this birthday gift is going to a significant other or an old friend, noting that they can enjoy it for decades to come. If youre looking to spend less than $1,000 on a good TV, check out these expert-recommended models.

Entering any new decade brings the stress of change, but your fifth decade can prove to be a particularly unsettling one, according to the folks we spoke to. Du Petit Thouars told us her go-to gift for someone anxious about their birthday is this solid brass incense burner that she calls an elevated way to burn incense (and looks good whether in use or not). The vessel burns the incense horizontally and has a curved catch-all brass tray underneath, minimizing mess and making it easy to clean, too.

According to Athena Hewett, the founder of skin-care studio Monastery, stylish candles that dont look millennial are increasingly hard to find. Thats why, for a 40th birthday, she recommends going for something more unexpected and sophisticated, like one of these sculptural candles from Carl Durkow. The unscented beeswax designs come in fun shapes that Hewett says are perfect for any mantel or shelf, and will draw attention whether lit or not.

If youd rather give a sophisticated candle that also smells nice, Fortini told us these candles from the cult perfumer Regime des Fleurs that she loves to give her friends would make for a great 40th-birthday gift. They come in a lovely porcelain vessel that looks like an antiquity unearthed, she explains, adding that recipients can use the vessel to hold pens or makeup or change after the wax burns down. And they smell divine, she promises.

At 40, life is complicated enough as it is, Choa told us. To simplify it somewhat, he recommends giving several pairs of these Albert Kreuz socks in the striking red color. With matching socks, he says, your recipient will never need to sort after laundering ever again, and their socks also wont look like anyone elses. And once they start wearing them, Choa says from experience that others will notice and, soon enough, the recipient will be set up in perpetuity for recurring supply.

For the well-coiffed woman or man who might want to start their new decade with a quality hairbrush, Hewett says this Yves Durif comb-and-brush set that she keeps spotting feels like the Mason Pearson for our generation. A well-made brush like this one, she says, offers a more luxurious massage for your scalp, is better at detangling, and stimulates the oil in the follicles to smooth and shine your hair. (Hewett notes that this one is the perfect size for throwing in your bag, too.)And like any good quality tool, its excellent craftsmanship is just obvious to an adult, she adds.

Heyman told us that jewelry is one of two gifts (along with that cheese) that would assuage her slight dread, because its personal, meaningful, and, if chosen well, cool as hell. If youre looking for inspiration, she says one of the best pieces of jewelry she ever received is an ID bracelet with I Love You in her daughters handwriting engraved onto it. While Heymans style from the ultra-high-end jeweler Sidney Garber is no longer available, this 14-karat Mejuri bracelet, while still expensive, costs a fraction of Garbers pieces and comes with the option to engrave for no extra cost. Mejuri, we should note, is fast becoming a Strategist favorite for special jewelry, with some of its hoops making an appearance in our list of 130 gifts you can buy for less than $104 (all of which were recommended by people with exacting taste). The brand is also one of nine that our own staffers recently tested jewelry from, with our tester concluding that Merjuri uses quality materials for less [money] than what youd typically pay at a traditional retailer.

According to Hewett, just because youre turning 40 doesnt mean youre unable to keep up with fashion trends you might just want a more elevated way to do so. One such trend she is keeping up with are scrunchies, noting that the 90s hair accessory is having an extended moment and not just among VSCO girls and other teens. For an age-appropriate twist on the scrunchie, she pointed us to this nice and classic satin-silk option from Sophie Buhai a designer whose scrunchies weve written about before with a name that kind of says it all.

If the trend catching your recipients eye is tie-dye, a 40th-birthday-appropriate option that will help them to fit in at Grateful Dead shows and the school playground alike, according to Hewett, is this refined spin on the tie-dye tee from designer John Elliot.

A person approaching 40 will be interested in preserving their best stuff for the next 40 years, says Schuman, who recommends giving both men and women a fashion essential that many overlook: A pair (or two or three) of shoe trees. Shoe trees are super important to maintain good shape and order for both dress shoes and expensive sneakers, he told us, adding that theyre a great way to maintain what we already own. Schuman doesnt have a favorite style: Buy the best you can afford, he told us. While there are less expensive plastic options, these shoe trees made of 100 percent cedar have a handcrafted look that makes them a bit more giftable, and are also quite functional (in addition to helping shoes keep their shape, the cedars moisture-absorbing ability will help dry them out between wears).

In kind of the same vein, du Petit Thouars says these made-in-Italy scented tablets from Santa Maria Novella are a great gift for the clotheshorse about to turn 40. My husband first gifted me these, and I now cannot live without them in my closet, she says. Rest them on any free space in your closet, and the rose-infused wax will have your clothes smelling like a summer garden (just note that the brand says not to let them touch any fabric directly).

For a practical but still luxurious gift, Murphy recommends giving this anti-aging cleanser and moisturizing face oil from True Botanicals, a brand that she describes as a beautiful, all-natural skin-care company with products that are good for the body and for the planet. According to Murphy, the moisturizing face oil fights the appearance of fine lines and wrinkles (True Botanicals calls it our best-selling moisturizer), and the cleanser purifies while gently cleansing, without stripping skin. She adds that they come in amber glass bottles that would look very nice on the shelves of a medicine cabinet.

For the new 40-year-old who is also a passionate gardener (indoors or out), du Petit Thouars recommends this book on foraging and arranging. I like their approach to flower arranging with wild plants, she told us, adding that it reminds her of her summers spent flower-picking and arranging at her childhood home outside Paris.

Fortini also says the right book can make for a great 40th-birthday gift, noting that the best book to give would be one that has meant something to you personally, with a note explaining why. Didion, the collected 1960s and 1970s work of author Joan Didion, is the one shed give to anyone she knows turning 40, she says.

If the 40-year-old in your life is always jotting things down, du Petit Thouars says they might appreciate a more elevated notebook in which to do so. Everyone needs a classy notebook at 40, she says, recommending this illustrated option from Herms. It may not be cheap for a notebook, but it is cheap for Herms, and would allow you to surprise someone with something from the luxury brand without breaking the bank.

Actually good deals, smart shopping advice, and exclusive discounts.

The Strategist is designed to surface the most useful, expert recommendations for things to buy across the vast e-commerce landscape. Some of our latest conquests include the best acne treatments, rolling luggage, pillows for side sleepers, natural anxiety remedies, and bath towels. We update links when possible, but note that deals can expire and all prices are subject to change.

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The Best 40th Birthday Gifts, According to People Whove Reached (or Are About to Reach) 40 - New York Magazine

Recommendation and review posted by Alexandra Lee Anderson

Anti-Aging Medicine | The Center for Natural & Integrative …

Our Integrative Approach to Slowing Aging and Increasing Longevity

During your two hour visit, our physicians will get detailed history and discuss your current state of health, focusing on your concerns. A brief physical exam is performed and laboratory testing, including analysis of blood, urine, and stool samples may be recommended. Any previously diagnosed medical conditions will be considered and additional diagnostic testing may be performed. Electrocardiograms (EKG), exercise tolerance assessments, and heart stress tests may be advised if you are at risk for heart disease. Depending on your age, mammograms, bone density scans, prostate exams, colonoscopies, and ultrasounds will be recommended where appropriate. All of these physical evaluations will help determine your current physical age and help steer our treatments toward slowing the aging processes you are undergoing.

As your physicians complete the analysis of all the medical tests, they can begin to outline a personalized anti-aging program for you. The results of your blood, urine, and stool tests will help identify physiological imbalances that might be impacting the quality of your health.

Hormone replacement therapy is the essence of anti-aging medicine. By restoring your bodys levels of hormones to those of a young adult, you are taking one giant step away from the aging process. At the Center, our physicians are well-versed in the safe use of natural hormones to boost energy, vitality, and libido, as well as lower risk ofheart disease,osteoporosis, and many other degenerative diseases.Read more about the natural hormone therapies we offer, including testosterone, estrogen, DHEA, human growth hormone, and thyroid replacement. Neurotransmitter levels that affect sleep and mood are also tested for and corrected.

Dietary fat is a major source of free radicals. Many age-related and degenerative diseases, including cancer, arthritis, atherosclerosis, Parkinsons disease, and cataracts, are associated with increased intake of fat. In addition, dietary sugars chemically alter the proteins in your body, ultimately damaging your immune system and kidneys.

Following a low-fat, low-sugar diet is one of the most effective ways to slow down the aging process. More important, our practitioners will teach you how to shop for and prepare low-fat, low-sugar meals to make them part of your regular diet. High blood cholesterol, for example, can put undue pressure on the cardiovascular system, causing the heart muscles to age prematurely. By identifying this particular risk, we can increase the longevity of your heart and your life.

Depending on your case, a detoxification program may also be recommended. By reducing the toxin levels in your body, damage to your cells and stress on your cell repair systems can be minimized and ultimately slow the aging process. Carefully regimented dietary restrictions may be suggested to cleanse the body of ingested toxins it may be harboring.

Chelation therapy to specifically reduce levels of mercury, lead, and arsenic is also available. We have practitioners available to guide you through a complete detoxification program including the infrared sauna.

The path toward greater longevity requires a steadfast commitment to healthier habits beyond these specific treatments. It sounds simple, but keeping active, eating a diverse diet rich in antioxidants, and getting plenty of sleep are some of the most natural, effective anti-aging measures that one can take. As with all of our therapies, we can help devise a plan centered on achievable goals for your health that mesh well with your lifestyle and personality.

We have a variety of nutriceuticals and phytonutrients available to enhance your anti-aging therapy. These nutritional supplements are all natural and based on thousands of years of traditional herbal medicine. Your physician will work with you to incorporate these into your diet to encourage better overall health and strengthen your immunity to prevent disease. Be sure to communicate with all your doctors before incorporating any new therapies, as some of these supplements are still undergoing FDA evaluation and may also have interactions with other medications you are taking.

Many of the supplements we recommend and offer to patients as a convenience are termed medical foods and all are extremely effective in optimizing health and vitality. By helping to limit the damage done to DNA by free radicals, nutrients can help slow aging at the cellular level by reducing the strain on the DNA repair machinery and keeping our cells healthier longer.Intravenous nutrition with vitamin C and B vitamins all have anti-aging properties and provide energy to our cells. Alpha-Lipoic Acid is a universal antioxidant and is very powerful just as is glutathione. These therapies are invaluable in ensuring that we get the nutrients we need because oral supplementation may not be effective due to absorption issues.

Our brains are affected by the same processes that contribute to overall aging. How well we take care of ourselves affects not only our general health, but also our mental function. We utilize powerful herbs such asGinkgo biloba, vinpocetineand ginseng to help boost brain power and increase mental energy and stamina for overall health and well-being. Intravenous nutrition is also invaluable as is plaque therapy.

Our doctors will prescribe a preventative and comprehensive treatment plan that is tailored to your needs and fits into your lifestyle. Our team at The Center for Natural & Integrative Medicine will regularly monitor your progress and track the effectiveness of your program making adjustments if necessary. Our goal is to support you and advise you every step of the way. We work in conjunction with your existing doctors to ensure the best possible care.

Do you feel like age is catching up with you? Have you noticed wrinkles, hair loss, reduced physical energy, or diminished sex drive? Do you get sick more often than you used to?Although we typically think of the external signs of aging, with the emergence of wrinkles and graying hair, aging is also an internal process that has roots at the cellular level. All the organs of our bodies are made up of individual cells that have limited life spans. While we are young, our cells divide many times as we grow. Our cells are capable of repairing themselves, communicating with other cells, and interacting with all the physiological molecules that ultimately define our current state of health. Scientists have discovered, however, that our cells have a limited capacity to divide and repair.

Laboratory studies have shown that cell aging patterns are genetically encoded and cell death occurs along a predictable schedule of events for different cell types. Our DNA is bundled into chromosomes, each capped with repeated sequences called telomeres. During cell division, the cell attempts to make a complete copy of itself, including all of its DNA, but researchers have discovered that these telomeres shorten over successive cell divisions. The telomeres help protect the DNA from radical arrangements (that might cause cancer, for example) and they can be lengthened by an enzyme called telomerase. If the telomeres are allowed to become too short, however, the cell senses this problem and puts in motion a cascade of events that will result in its own death. This mechanism of programmed cell death, also called apoptosis, is a critical part of proper human development and a natural part of the life cycle of a cell.

A cells life also comes to a close if its DNA sustains damage more quickly than the DNA repair machinery can compensate for it. One of the major causes of DNA damage in our cells is the presence of free radicals. These highly reactive molecules can cause significant damage to both the proteins and the DNA in our cells by undergoing chemical reactions with them. The free radical theory of aging suggests that these molecules accumulate naturally over time and that our DNA repair machinery copes less and less well with the damage. Thus, our physical aging would be correlated with this decline in the health of our individual cells. Free radical damage has also been scientifically linked to many age-related medical conditions, including arthritis, Alzheimers, heart disease, diabetes, and cancer. Intriguingly, it has been shown that antioxidants can slow or stop the damage caused by free radicals by helping to balance the chemical reactions in the cells. Antioxidant levels can be increased by adding antioxidant rich foods to the diet or by taking nutritional supplements.

Because our cells become less resilient as we age, so do our bodies. We become more susceptible to illnesses and once we get sick, it takes longer to recover. Wounds may also take longer to heal. As some cells begin to lose function, they cease expressing hormones, further shifting our physiological balance. All of the changes to our immunity, metabolism, and body chemistry can have a huge impact on our health and well-being as we age.

Some of the signs of aging are superficial. Wrinkles develop, particularly near the eyes, mouth, and other expressive parts of the face. As the skin begins to lose its elasticity and the layer of fat beneath the skin begins to diminish, the face can take on a further wrinkled or gaunt appearance. Age-related hair loss may also occur in both men and women due to hormonal changes or genetic factors.

Our immune systems and cell repair systems gradually become less efficient as a person ages, responding less quickly and vigorously to challenges. People may become more susceptible to illnesses and, once acquired, find them harder to recover from. Wounds may heal more slowly and muscle soreness after exercise can linger longer. If cell and tissue damage accumulate more quickly than the body can make repairs, cell death will become more frequent, causing more aging related symptoms and maladies to emerge.

Significant hormonal changes also take place during aging. For women, the most radical change occurs with the onset of menopause, in which the ovaries lose function. In addition to the cessation of menstruation, there are other physiological changes that occur due to the sudden lack of estrogen production in the body. The changes in bone mineral density can lead to osteoporosis, increasing the risk of bone fractures. Sleeping patterns, libido, and mood may also be effected by menopause. In men, testosterone production continues during aging, though levels begin to decline after age forty. This reduction in testosterone can lead to hair loss, muscle mass reduction, and sexual dysfunction.

Some mental symptoms associated with aging include increased forgetfulness and difficulties learning new things. The brain becomes less pliable during the later years of life, though the chemical and structural changes that might mediate this phenomenon are unclear. The rate of cognitive decline varies from person to person and only drops steeply for some near the very end of life.

While aging is a natural phenomenon, there are also lifestyle choices and other factors that can accelerate the process and reduce a persons longevity. In other words, it is possible for people to prematurely age their bodies and shorten their lives.

Too much exposure to the sun can age a persons skin prematurely. The ultraviolet (UV) rays in sunlight can damage DNA, hastening skin cell death. UV overexposure can also contribute to the breakdown of the matrix of collagen and elastin that forms the fleshy layer of skin beneath the surface. As the skin weakens, it loses its spring, sags, and wrinkles begin to form. The skin can also become freckled, dry, or blotchy. DNA damage from UV light can also increase the risk of developing skin cancer.

Excessive alcohol, caffeine, or nicotine can also accelerate the aging processes through direct cell damage or complications following long term use. Nicotine, for example, both increases the heart rate and constricts blood vessels, elevating blood pressure and putting undue pressure on the cardiovascular system. The complications of hypertension, atherosclerosis, and other cardiovascular diseases can dramatically reduce both longevity and the quality of the final years of life.

Poor nutrition and sedentary lifestyle can also push the metabolic balance of the body toward a more limited life span by increasing the chances of obesity, diabetes, high blood pressure, and many other life-shortening conditions. Perhaps ironically, nutrition and exercise are often neglected in the interest of saving time.

The accumulation of toxins in the body can contribute to premature aging by stimulating the formation of free radicals or causing other types of cell damage. While pollutants in the air and water certainly contribute to a persons toxin levels, many toxins are consumed unknowingly. Food additives and preservatives are quite common, even among superficially healthy foods. Hormones, pesticides, and industrial chemicals may also taint non-organic foods bought at the grocery store.Insufficient sleep can also contribute to aging by denying the body its much needed rest and repair. Information processing and memory formation occur as the brain progresses through the phases of sleep, sharpening the mind while it rests. Sleep can also impact hormones, metabolism, and immunity, all of which influence our states of health. Chronic sleep deprivation and the resulting sleep debt can lead to a multitude of persistent health problems, affecting a person physically, mentally, and emotionally.

Finally, stress can prematurely age the body in numerous ways. Researchers have shown that stress can increase the speed with which telomeres shorten, causing cell death to occur more rapidly. Stress can also increase blood pressure, aging the cardiovascular system, and put significant strain on the nervous system and immune system. Stress can contribute to hair loss and wrinkle formation, both which can also make a person appear older than they are.

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Anti-Aging Medicine | The Center for Natural & Integrative ...

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Treat yourself to a healing vacation – Philippine Star

Treat yourself to a healing vacation

Boosting ones immunity is of paramount importance nowadays. Do you even know where to start?

If you are looking to escape into a peaceful retreat and at the same time learn how to change your lifestyle and improve your health, you can check out the various programs offered jointly by go2Health and Sonyas Garden. Through a healing vacation, you will learn the science of using food, sleep, exercise and nature as medicine in addressing the root cause of your disease.

One such retreat is happening on March 30 and 31 and we asked program lead Dr. Oyie Balburias about his insights into womens wellness (March being Womens Month).

The Philippine STAR: What are the most prevalent lifestyle problem of working women?

Dr. Oyie Balburias: Due to their professional duties, functions and responsibilities juggling their roles as a mother and caregiver to the family working women suffer from chronic stress that, if persistent, will result in hormone imbalances. Persistence of hormone imbalances as a result of chronic stress later on leads to several conditions and diseases affecting womens health, namely obesity, infertility, irregular and painful menstruations, PCOS, endometriosis, fibroids and infertility, to name a few. Hormone imbalances will also impact on the sleep quality and quantity, which in the end will further perpetuate the imbalance.

As a lifestyle coach and medical practitioner, could you share three lifestyle hacks or adjustments women can do be healthier?

Always have me time. Always have time for relaxation and engage in de-stressing activities (meditation and meditative exercises) or self care so the stressors will not be chronic and persistent. In doing so, there will be a balance of the sympathetic nervous system (fight) and the parasympathetic nervous system (relaxation response). Balance of this system will prevent the biologic response of our body to chronic stress which leads to hormone imbalances. Have a balanced and optimal nutrition. Its not the number of calories, but the composition and quality of food that you are eating that will impact on your metabolism. Foods that are whole, real and unprocessed are best. Every macronutrients (fats, proteins and carbohydrates) and micronutrients (vitamins, minerals and phytonutrients) are needed by our body. Eliminating one will result in the body system creating a biologic response.

Breathe. If you find yourself overwhelmed by chaos and challenges, the best way to deal with it is to breathe and practice mindfulness.

Sleep deprivation and sedentary lifestyle will further aggravate and perpetuate hormone imbalances. Chronic sleep deprivation will affect their energy level, which leads to fatigue. Chronic fatigue leads to a sedentary lifestyle, which then further contributes to fat gain and obesity. Hormone imbalances contribute to cravings for carbohydrates and simple sugars, further aggravating the condition.

Eight hours is the amount of time that our body needs in order for the different stages of sleep to occur. NREM and REM stages of sleep, the deep sleep and not so deeper part of our sleep. In each stage, different biological, biochemical and physiological process are happening in order to prepare our resiliency for the following day. Adequate sleep is required for numerous biochemical reactions in the body. It is essential for normal cellular and tissue function, because numerous restorative functions occur during sleep, especially stages 3 and 4. Optimal sleep is important for growth hormone(GH) secretion. GH is the most potent hormone for fat metabolism. If there is a dysfunction with sleep in regard to inadequate quantity or depth there can be numerous adverse effects in the body.

Botanicals for dysmenorrhea include cinnamon bark, peppermint oil and ginger root. To decrease hot flashes, you need red clover and sage. For fibroids (myoma) and endometriosis, take turmeric, rosemary leaf and milk thistle.

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Dr. Oyie is a certified Functional Medicine practitioner and is European-board certified in Nutritional Medicine, as well as in Anti-Aging Medicine. Catch more of Dr. Oyies healthful and helpful insights in the Executive Health Retreat, which is open to both male and female participants. For inquiries, call or SMS 0917-1343100.

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Treat yourself to a healing vacation - Philippine Star

Recommendation and review posted by Alexandra Lee Anderson

To Turbocharge Anti-Aging Treatment, Just Add… a Protein Found in Fruit Flies? – Singularity Hub

The hunt for the elixir of life is such a universal mythological trope that to talk about it in the context of science seems almost ridiculous. But breakthroughs in the last decade have made the impossible seem possible, and researchers are quickly converging on the consensus that aging may well be a disease that we can treat just as easily as any other.

Impressive results in animals that have had their lifespans boosted by up to 40 percenthave started making their way into humans. Some trials are more questionable than others, but most promisingly there seem to be multiple potential avenues, from cocktails of common drugs to gene therapies and stem cell treatments.

Stem cells are particularly promising, because they can be coaxed into becoming any kind of cell before being transplanted to treat damaged tissue. These therapies often fail to work well in older tissue, though, limiting their future use in older patients who could need them most. This appears to be because these tissues have significantly higher levels of inflammation that prevent stem cells from properly integrating.

Now Portuguese researcher Joana Neves has won the 2019 Sartorius & Science Prize for Regenerating Medicine & Cell Therapy for her discovery of a way to sidestep this roadblock and significantly increase the success of stem cell treatments.

Because of the central importance of tissue repair to all organisms, Neves assumed that many of the mechanisms behind it would be shared among all animals. So she started looking at proteins produced by immune cells in the well-known animal model of the fruit fly.

She discovered that a poorly-understood protein known as MANF (mesencephalic astrocyte-derived neurotrophic factor) plays a crucial role in reducing inflammation in fruit flies. More importantly, she found that mice and humans also produce it, and its prevalence reduces in all the species as they age, suggesting it plays a key role in limiting age-related inflammation.

That prompted her to see if introducing MANF would boost the effectiveness of stem cell treatments in older animals. She used the protein in combination with a procedure that uses stem cells to replace degenerating photoreceptors in the retina of older mice and found it greatly improved the restoration of vision.

Going further, her research team then investigated whether MANFs anti-inflammatory effects could have more general age-defying benefits. Previous research had already demonstrated that infusing old mice with blood from younger ones could reduce various signs of aging, and by carrying out similar experiments the team showed that MANF is one of the factors responsible for that outcome. They even showed that directly injecting mice with MANF could have similar effects.

Translating these ideas to treat other diseases and for use in humans will take some time, but the research chimes with work on an emerging class of drugs known as senolytics. These are drugs that kill senescent cells, which are zombie cells that become more prevalent as we age and spew out harmful chemicals that result in chronic inflammation.

Senolytics are generally seen as a broad-spectrum treatment that could help stave off multiple conditions at once, but they could also be used to create a more hospitable environment for stem cell treatments just like MANF.

There are still plenty of barriers to bringing any of these treatments to the clinic, from the difficulty of producing stem cells to the challenges of regulating treatments for aging (a condition we still dont formally class as a disease), or fighting back against the huge number of bogus treatments that threaten to undermine trust in the field. But given the huge potential for near-term impact, theres growing momentum.

Weve moved from being able to extend health and lifespan of simple organisms like yeast and worms and flies to being able to do this quite easily in animals, in mice and monkeys, David Sinclair, director of the Center for the Biology of Aging at Harvard Medical School, told the Harvard Gazette.

He added that instead of trying to treat one disease at a time, he believes we can develop medicines that will treat aging at its source, therefore having a much greater impact on health and lifespan than drugs that target single diseases.

The wheels are in motion for us to find out.

Image Credit: Monika Robak from Pixabay

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To Turbocharge Anti-Aging Treatment, Just Add... a Protein Found in Fruit Flies? - Singularity Hub

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Skin Care Benefits From Honey- Based Products – StyleNest

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Honey is a natural sweetener and taste enhancer. Depending on the source of the nectar, Honeys composition can vary in texture as well as taste. Today, over 300 varieties of Honey are available in the market. Still, Honey, an all-rounder of natures best remedies, is also known for its medicinal properties. For illustration, Honey has been used in medicine since Ancient Egypt, mostly due to its wound-healing properties and antibacterial action. However, its antimicrobial features are also regularly used in the beauty industry. When applied to your skin, Honey creates an invisible shield to fight all the acne-causing bacteria, damage, and environmental factors. This magical substance can tackle many skin issues, and even if you do not have any major ones, you would still feel the bliss while using honey-based beauty products due to its calming and moisturising superpower. With all this in mind, let us see what wonders can Honey do for your skin.

Honey and Honey Bee By-products Used for Skincare

Raw Honey is what is most commonly used in the production of beauty products. This type of Honey comes straight from the honeycomb. It is neither heated or filtered. Raw Honey is removed from the hive and directly bottled, so it contains small amounts of yeast, wax, and pollen. It appears cloudy or opaque precisely because it includes these extra elements. Raw Honey is also a natural exfoliator, which means that it can take off dry, dead skin and reveal new skin cells when applied on your face.

However, it is not just Honey that boosts your skin health. Propolis, another honey bee by-product, has many appealing qualities. Science has found that propolis, made from the chewed buds of some trees and conifers mixed with bees saliva, is antibacterial, antifungal, antiviral, anti-inflammatory, and antioxidant. This vital substance protects bees against diseases. It has the power to help in balancing, healing, and soothing problematic skin. It also stimulates the rate of cell growth and decongests pores. Propolis also protects against bacteria and works as a great anti-inflammatory agent. It gives the skin smoother, softer texture, and a calmed complexion.

Bee wax is a natural secretion from wax glands on the sides of the body of honey bees. Its primary use is as a building block for the bees honeycomb cells in which they raise the young, and store Honey and pollen. This honey bee by-product, heals and softens skin, and is a vital antibacterial agent. It can help fight conditions like acne, dry skin, eczema, and stretch marks. Raw beeswax is mainly used in the production of skin care moisturisers and lotions.

Royal jelly is the queen bees great source of food. It is rich with a high concentration of vitamins B5, B6, and amino acids. Many people believe it is a potent antioxidant and a unique rejuvenating substance that promotes tissue growth, muscle, and cell regeneration. Royal jellys skin benefits include moisturising, reducing redness, adding collagen to the face to help combat anti-aging, healing acne, and scars, and getting rid of oiliness in the face.

Honeys Skincare Benefits

Due to its extraordinary attributes, modern medical science uses Honey in chronic wound management and combating infection. Nevertheless, Honey is also used in traditional and alternative medicine for treatment for a variety of clinical conditions. In the beauty sector, Honey is used as a skin moisturiser, a humectant, an antibacterial, and a flavouring ingredient. It is mostly used due to its four main skin-saving benefits:

#1 Complexion boost Honey is extremely moisturising and soothing, so it helps create a glow. Honey can nourish, hydrate, and moisturise all skin types. The enzymes present in Honey enable it to flow into your skin while conditioning it and softening it from deep within quickly. Moreover, since Honey is a natural humectant, it can draw moisture from the air into your skin, keeping it fresh, hydrated, and healthy all day long.

#2 Acne treatment Honey is naturally antibacterial, so it is excellent for acne treatment and prevention. However, the Honey used in the beauty product of choice must contain healthy bacteria. The reason for this is that these bacteria can activate your immune system and help with inflammation, redness, and heal blemishes. Additionally, because Honey keeps the skin well-hydrated and balanced, it can also help control the production of oil in your skin, which further prevents the formation of acne.

#3 Anti-Aging Honey is full of antioxidants, so it is the perfect ingredient for slowing down aging. These natural antioxidants help control the formation of wrinkles and fine lines. Honey can significantly improve your skins elasticity, making it look youthful and glowing.

#4 Anti-Inflammatory Alongside Honeys Honeys antimicrobial properties, it offers up a substantial serving of antioxidants that accelerate the healing of the skin. For this reason, many suffering from sensitivity or skin conditions such as eczema or rosacea see particular improvements when using Honey or honey-based skincare products. Manuka honey, in particular, boosts skins natural immunity by strengthening the skin barrier.

Popular Honey Beauty Products

Thanks to its remarkable, antibacterial, and youth-boosting properties, Honey is used in the formulation of a wide range of beauty and personal care products. Namely, Honey is often used in hand care creams since it softens, moisturises, and protects dry hands, especially in winter. Due to its humectant powers, which means it draws moisture to the skin and keeps it hydrated, Honey is the ideal ingredient for bath products and after bath lotions. And, precisely because of these humectant abilities, combined with its antioxidant properties, Honey is also a popular ingredient in the production of eye and facial make up cosmetics. It is also extensively used in the production of removing makeup lotions since it can help unclog pores while concurrently delivering moisture to dry skin.

Final Thoughts

Honey is the beauty industrys secret ingredient in the production of many skincare products, especially facial, hand care, and body care creams. Its ability to softens, moisturises, and defends the skin makes it a favourite choice between consumers. Though raw Honey is more expensive than other kinds of Honey (which also makes beauty products containing it more costly), it is relatively reasonable compared to other skin cosmetics for your face and body. Honey skin looks, which is more and more trendy nowadays, means above all having a well-nourished, shiny, and plump face and body skin. Who would not want that?!

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The Serum Concentration of Anti-Aging Proteins, Sirtuin1 and Kl | CIA – Dove Medical Press

Edyta Zbroch, 1 Angelika Bazyluk, 1 Jolanta Malyszko, 2 Ewa Koc-Zorawska, 1 Alicja Rydzewska-Rosolowska, 1 Katarzyna Kakareko, 1 Tomasz Hryszko 1

1 2-nd Department of Nephrology and Hypertension with Dialysis Centre, Medical University, Bialystok, Poland; 2Department of Nephrology, Dialysis and Internal Medicine, Medical University of Warsaw, Warsaw, Poland

Correspondence: Edyta Zbroch2-nd Department of Nephrology and Hypertension with Dialysis Unit, Medical University, Sklodowskiej Curie 24a, Bialystok 15-276, PolandTel +48 85 8317872 Email

Introduction: Sirtuin1 (SIRT1) acts as an anti-aging protein due to anti-apoptotic, anti-oxidative and anti-inflammatory effect and is implicated in several diseases including diabetes or cardiovascular problems. SIRT1 renal overexpression indicates oxidative stress. Similarly, Klotho was primarily exposed as anti-aging factor. It is primary produced in kidney. Its deficiency is associated with progression of chronic kidney disease and heart disorders.Purpose: The aim of the study was to assess the serum concentration of sirtuin1 and Klotho in hemodialysis (HD) patients compared to healthy volunteers in regard to age, blood pressure control, residual kidney function (RKF), diabetes, cardiovascular disease, dialysis vintage and type of dialyzer.Patients and Methods: The serum level of SIRT1 and Klotho was evaluated using ELISA tests in 103 HD patients, median age 67 years and in 21 volunteers. Blood pressure, RRF, echocardiography and dialysis parameters were assessed. HD group was divided according to the presence/absence of RKF.Results: The serum SIRT1 level was higher (28.4 vs 2.71ng/mL, p< 0.0001) and Klotho was lower (433.9 vs 756.6pg/mL, p< 0.0001) in HD then in control group. Klotho was lower in those without RKF (387.2 vs 486.2pg/mL, p=0.028). SIRT1 positively correlated with hemodialysis vintage. Klotho negatively correlated with left ventricular posterior wall thickness. There was no significant relationship between SIRT1 and Klotho level and age, blood pressure control, type of dialyzer, Kt/V and diabetes. Multivariate analysis revealed association of SIRT1 with ejection fraction (B 0.72; p=0.32).Conclusion: Elevated SIRT1 and lower Klotho concentration are associated with impaired kidney function. The decrease in levels of Klotho may also indicate heart hypertrophy in hemodialysis patients. The role of anti-aging proteins, particularly SIRT1 as biomarkers/predictors of oxidative stress, inflammation and cardiovascular diseases need further examination.

Keywords: sirtuin1, Klotho, chronic kidney disease, hemodialysis

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at and incorporate the Creative Commons Attribution - Non Commercial (unported, v3.0) License.By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms.

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Invigorating procedure makes thinning hair grow thicker – Florida Today

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Dr. Emran R. Imami and medical assistant Maggie Smith work on a patient undergoing non-surgical hair restoration using techniques designed to stimulate new cell growth.(Photo: TIM SHORTT/ FLORIDA TODAY)

Most of us have some particular part of our anatomy that, well, bugs us.

It could be our nose, ears, neck or even the derriere that could use improvement, according to the lens through which we see ourselves.

For Leslie Burgett, its her hair.

Ive battled with it off and on for years, the Merritt Island resident said.

Her genetics predispose Burgett to alopecia, thinning hair in certain areas of the scalp. To be honest, however, Burgetts hair, while not voluminous, wasnt that scarce, either.

Dr. Emran Imami is certified by the American Board of Surgery and is an invited Fellow of the prestigious American College of Surgeons.(Photo: PROVIDED PHOTO)

A lot of people probably wouldnt have noticed, but its obvious to me, she said. When you look at yourself in the morning, what you look like sets the rest of the day, and I didnt like the way my hair looked.

Through the years, the decades, even, Burgett continued the battle with her locks. She underwent a thyroid test, since this gland could cause hair loss if malfunctioning. Thyroid was not the issue.

She tried minoxidil back when you needed a prescription for the product. Used to treat baldness in a topical format, minoxidil was originally developed as an antihypertensive vasodilator. It wouldhave helped grow hair on Burgett, but it also lowered her heart rate so much she had to quit.

After a death in the family, Burgett found that the antidepressants she was taking were growing her hair as well as loweringher stress.

Polydioxanone (PDO) Threads are inserted to stimulate hair follicles to grow. Dr. Emran R. Imami uses this non-surgical hair restoration technique at Imami Hair Restoration in Melbourne.(Photo: TIM SHORTT/ FLORIDA TODAY)

For a long time, my hair was fine, she said.

However, dropping the medication was not kind on her hair.

I started having the thinning I had years ago, said Burgett.

Treatment with PRP, or protein-rich plasma, worked well, but Burgett would have to go back to her doctor every three months to have blood drawn. A centrifuge would isolate and concentrate the healing portion of her blood, which would then be injected into her scalp to nurture flagging hair follicles.

It worked pretty well, she said.

It worked even better when she added PDO threads to the treatment.

Polydioxanone, or PDO, has been used for years in aesthetics for non-surgical facelifts and wrinkle control. The medical grade thread, made of protein and thinner in circumference than hair, both relaxes tendons and muscles in an area and simultaneously improves blood flow.

Polydioxanone (PDO) Threads are inserted to stimulate hair follicles to grow. Dr. Emran R. Imami uses this non-surgical hair restoration technique at Imami Hair Restoration in Melbourne.(Photo: TIM SHORTT/ FLORIDA TODAY)

They work with the face. They also work with hair, and patients with androgenetic alopecia have experienced hair regrowth after PDO threads were inserted into their scalps.

The threads increase inflammatory response, which in turn increases new blood vessels, said Dr. Emran Imami of Imami Skin & Cosmetic Center in Melbourne.

In medical terms, the threads perform a selective inflammatory response by encouraging the body to heal itself.

"Its like watering a plant, Imami said.

Burgett has a glowing report on her PDO threads experience, even though it has been just a couple of weeks since the procedure, which involves inserting into the scalp a series of tiny needles preloaded with the threads. The threads stay beneath the skin after the needle is withdrawn.

Ive noticed less hair falling and more hair growing back, she said.

Because the threads are fully absorbed in four to six months, the procedure should be repeated every six months, but Burgett has no problem with that.

I didnt feel a thing and I was out of there quickly, she said. After the procedure, my head felt a little heavy, like you had a hat on, but by the next morning, that feeling was gone and I was back to normal.

A research study presented at the 12thInternational Conference on Cosmetic Dermatology and Hair Care noted that patients experienced significant reduction in hair loss with PDO threads. Hair regrowth increased from an average of 65 hair follicles per centimeter of scalp to 93.

Polydioxanone (PDO) Threads are inserted to stimulate hair follicles to grow. Dr. Emran R. Imami uses this non-surgical hair restoration technique at Imami Hair Restoration in Melbourne.(Photo: TIM SHORTT/ FLORIDA TODAY)

Imami sees using the threads as part of a bigger treatment picture that can include, as in Burgetts case, PRP, and also low-level laser, daily use of vitamins such as B12 and herbal shampoos with red clover extract, and other treatments to stop, slow or even reverse hair loss. For good measure, add a touch of scalp micropigmentation to create the illusion of hair follicles through what is essentially a tattooing process.

There has been a marked increase in the science of anti-aging, reparative and regenerative medicine, and as such, there are several ways to preserve and grow healthy hair, said Imami.

Hair loss can be caused by hormonal or thyroid imbalance, diabetes, medications, genetics, stress and simply just the passage of time.

As you age, everything will thin, Imami said.

Because it usually happens gradually, hair loss often is not noticed until a significant loss has already occurred.

You have 100 hair follicles per centimeter and you can lose up to 75 percent of them and not look bald, Imami said.

The hair strands thin, and during the cycle of growth they may remain dormant for a longer period of time. Regrowth takes longer and longer, and eventually ceases altogether.

Catch them while they are still around, says Imami, or you may regret it later.

If you treat the follicles while they are still there, you can do something, but once the hair follicle dies, you cant get them back, he said. We want to maximize the growth phase of the hair cycle and the length of time it stays on the scalp, because if we can keep the hair on the head to last longer, the net effect is that you have more hair density.

Should you wait until the hair disappears, your only option is a transplant, which is effective, but takes time and is more expensive.

Burgett would rather skip the transplant and has no problem incorporating other different treatment modalities, as long as they keep hair on her head.

For women, hair is such an integral part of their self-esteem, she said.

For more information, call 321-312-4168 or visit

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Invigorating procedure makes thinning hair grow thicker - Florida Today

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Hilary Duff Shares Her "Busy Mom" Beauty Routine, Including Favorite Treatment for Melasma – What To Expect When You’re Expecting

Hilary Duff, who is mom to Luca, 7, and Banks, 1, recently shared her busy mom makeup routine with Vogue including the product she uses to treat her pregnancy melasma.

Im a busy mom, the actress says in the video. I dont have a ton of time to do my makeup, but this version today is on a day when I have my kids but also have a couple of meetings and I want to look like I put some effort in.

Just so you know, What to Expect may earn commissions from shopping links.Why trust our product recommendations?

Duff starts off her routine by washing her hands or using hand sanitizer. She then reaches for her toner.

One really cool thing that happened to me when I had babies is I got melasma, she shared, pointing to a dark spot near the top of her forehead.

Every day, I say a little prayer that its taking care of that dark spot right there, she says, rubbing onOle Henriksens Glow2OH Dark Spot Toner($29;

Other products in Duff's kit includeREN Clean SkincareKeep Young and Beautiful Anti-Aging Eye Cream ($44; andPerricone MDNo Makeup Foundation Broad Spectrum SPF 20 ($60;

Melasma is a commonskin condition that causes brown to gray-brown patches to develop, usually on the face. Also referred to as the mask of pregnancy, melasma appears when a sharp rise in estrogen and progesterone levels stimulates excess melanin production, also known as hyperpigmentation. As a result, your freckles and moles may look darker.

Melasma is especially common in darker-skinned women, or those of Asian and African descent, who have more pigment in their skin than fair-skinned people. Exposure to sunlight can make melasma worse.

The discoloration from melasma is temporary, though, and it usually disappears after you give birth or, for some women, after you stop breastfeeding.

Again, melasma tends to fade with time.

The problem with melasma is that there arent any permanent solutions, saysGary Goldenberg, M.D., assistant clinical professor of dermatology at the Icahn School of Medicine atMount Sinaiin New York City. Still, he says many treatments help.

How to Treat Melasma

Topical products that contain kojic acid or lactic acid are helpful, Dr. Goldenberg says.In aprevious interview withWhat to Expect, dermatologist Jessica Wu, M.D., also recommended topicals with azelaic acid and vitamin C to help brighten your complexion.

As for the toner Duff likes, Dr. Goldenberg says it contains the following ingredients that may help with melasma:

Also important? Applying SPF 30 to 50 daily. If you have melasma, Dr. Goldenberg also recommends doing your best to limit your UV exposure.

The minute your skin is exposed to UV, it can re-pigment again, he explains.This isnt just sun you get at the beach. This is also sun you get through a window or windshield.

Just remember that not all skin care ingredientsare considered safe for pregnant or breastfeeding women. If you have questions about a product that you're considering to treat dark spots, show it to your OB-GYN first.

If your melasma persists after you have your baby and it bothers you, speak to your dermatologist. They may be able to offer up individualized treatment that can help.

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Hilary Duff Shares Her "Busy Mom" Beauty Routine, Including Favorite Treatment for Melasma - What To Expect When You're Expecting

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Vitamin C and the Immune System: Nutritional Fortification to Support Defenses Against Viruses – WholeFoods Magazine

Note: The views and opinions expressed here are those of the author(s) and contributor(s) and do not necessarily reflect those of the publisher and editors ofWholeFoods Magazine. Information in this interview is intended for educational and scientific purposes only. It is not intended as medical or nutritional advice for thetreatment or prevention of disease. For medical advice, consult your personal health care practitioner.

The immune system defends the body from deadly invaders. The immune system detects a wide variety of agents and distinguishes them from healthy tissue. Most people refer to these invaders as germs. Germs may damage healthy tissue both directly, and by depleting essential nutrients from the body below critical levels. Once critically depleted, cells and tissues function improperly, furthering the downward spiral of illness towards death.

The way I look at the relationship, it is the failure of an undernourished immune system that results in diseasenot just the presence of germs.

A healthy immune system requires many nutrients, including vitamin C (1). Healthy neutrophils and macrophages (types of white blood cells in the immune system) contain 1 mM concentrations of vitamin Cthats 50-100 times higher than the concentration of vitamin C in the plasma (liquid part of the blood). A healthy person produces about 100 billion neutrophils per day. However, when the immune system detects germs and swings into action to destroy the invaders, its white blood cell productionand its need for vitamin Cincreases (2).

Leukocytes (white blood cells) are a major arm of the immune system. Leukocytes include the phagocytes (macrophages, neutrophils, and dendritic cells), innate lymphoid cells, mast cells, eosinophils, basophils, and natural killer cells. These cells identify and eliminate pathogens, either by attacking pathogens through contact or by engulfing and then killing them. These actions require vitamin C. Activation of neutrophil and monocyte oxidative bursts to kill germs alters the cell membranes to pull in dehydroascorbic acid and ascorbic acid from the blood to increase the vitamin C concentration within these cells ten-fold (from 1 mM to 10 mM).

The Linus Pauling Institute lists specific measures of functions stimulated by vitamin C as including cellular motility, chemotaxis and phagocytosis. Neutrophils, mononuclear phagocytes, and lymphocytes accumulate vitamin C to high concentrations, which can protect these cell types from oxidative damage.

Vitamin C, through its antioxidant functions, including regeneration of glutamine and vitamin E, has been shown to protect leukocytes from self-inflicted oxidative damage (3).

The 2000 RDAs by the Institute of Medicine teaches us that high intracellular concentration of ascorbate in leukocytes provides cellular protection against oxidant damage associated with the respiratory burst that plays a major role in the immune system (4). The respiratory burst (also called oxidative burst) is the rapid release of reactive oxygen species from various immune system cells. This rapid release kills invaders such as viruses. However, without adequate vitamin C, the immune cells would be unable to generate sufficient amounts of the reactive oxygen species needed to kill germs. Even worse, in severe vitamin C deficiency, the immune cells themselves would also be destroyed. As Michael Passwater, MT(ASCP) SBB, DLM, CSSGB (ASQ), stated in our interview on vitamin C and sepsis, If neutrophils (a type of white blood cell) lack vitamin C, they self-destruct. Instead of fighting the infection or clearing and rebuilding injured tissue, its internal peroxides and enzymes are released, damaging the surrounding tissuelike a firefighter using a flamethrower on a house fire (5).

Vitamin C is more than an antiviral. The reported deaths from the COVID-19 virus have involved multi-organ failure, acute respiratory distress syndrome (ARDS), and pneumonia. Paul E. Marik, M.D., and others have shown IV vitamin C to be effective against these conditions in sepsis (6).

In summary, it is a long-proven and uncontested fact that vitamin C has several nutritional functions, including supporting the immune system. As a dietary supplement, legally it can be stated that vitamin C supports a normal immune function. If someone is in the business of selling vitamin C, they cant legally refer to any disease functionincluding scurvy. Its best to suggest that anyone interested in vitamin C and any disease check with an appropriately informed physician or with an educator such as Dr. Andrew W. Saul.

In the clinic, it appears, based on dramatic successful case studies, that the relationship between vitamin C in the cells and immune function is a continuum, with a steady supply of higher levels of vitamin C allowing immune cells to sustain optimal function during the battle against invaders and through recovery. However, it would be helpful to confirm this with randomized double-blind trials.

Anyone selling vitamin C as a dietary supplement must follow the FDA regulation that any claim of a substance treating a disease makes that product an illegal unproven drug, which would have serious consequences to the seller. This is capricious and arbitrary, but it is the regulation, and, in my humble opinion, it seems to work to help reduce chaos and possible fraud in the dietary supplement category. While the regulation is far from being perfect, it provides some protection to both consumers and the supplement industry alike.

The medical profession, on the other hand, can legally treat diseases. Many physicians through the decades have successfully used high-dose vitamin C to treat diseases, including viruses. With so many lives at stake, It is important to educate everyonethe medical profession and laypersons alikeabout the safe and effective use of vitamin C as well as the nutritional functions of vitamin C. Therefore, I am calling on Dr. Andrew W. Saul, once again, to educate our readers, laypersons, nutritionists, and physicians on treating viruses with vitamin C.

Dr. Saul has been an orthomolecular medical writer and lecturer for more than 40 years. Dr. Saul has taught clinical nutrition at New York Chiropractic College and postgraduate continuing education programs. He was also on the faculty of the State University of New York for nine years. Two of those years were spent teaching for the University in both womens and mens penitentiaries.

Dr. Saul is editor-in-chief of the Orthomolecular Medicine News Service (OMNS) and has published over 200 peer-reviewed articles. His bestselling book Doctor Yourself has been translated into eight languages. He has written a dozen other books, four of which are coauthored with Abram Hoffer, M.D. Dr. Sauls educational website is, the largest peer-reviewed, non-commercial natural healing resource on the internet. He is a board member of the Japanese College of Intravenous Therapy. Dr. Saul was inducted into the Orthomolecular Medicine Hall of Fame in 2013. He is featured in the documentaries FoodMatters and That Vitamin Movie (

Passwater: Dr. Saul, thank you once again for educating our readers on vitamin C and health. You recently issued several press releases via the Orthomolecular Medicine News Service about vitamin C and COVID-19 (a current pandemic coronavirus). Do you know if anyone is following up with a clinical study?

Saul: There are at least three hospital-based clinical studies going on right now in China. I am in daily contact with one of the key researchers, Richard Cheng, M.D., Ph.D.

Dr. Cheng, who is a U.S. board-certified specialist in anti-aging medicine, early on in the outbreak stated, Vitamin C is very promising for prevention, and especially important to treat dying patients when there is no better treatment. Over 2,000 people have died of the COVID-19 outbreak and yet I have not seen or heard large dose intravenous vitamin C being used in any of the cases. The current sole focus on vaccines and specific antiviral drugs for epidemics is misplaced.

Dr. Cheng has also said, I have been calling for the use of large-dose IV vitamin C for the treatment of coronavirus (COVID-19) patients, and also for oral vitamin C for the milder cases, or for the prevention of this disease. He is dialoguing with more physicians and hospitals as you read this.

I am a member of the Medical and Scientific Advisory Board to the International Intravenous Vitamin C China Epidemic Medical Support Team. Dr. Cheng is its director. The associate director is Hong Zhang, Ph.D. My good friend and colleague Thomas E. Levy, M.D., JD is also on the board.

Details of the Wuhan protocol in English are posted at:

Protocol in Chinese:

The first approved study of IV vitamin C against COVID-19 involves 12,000 to 24,000 mg/day of vitamin C by IV. Dr. Cheng also specifically calls for immediate use of vitamin C for prevention of coronavirus (COVID-19):

A second clinical trial of intravenous vitamin C was announced in China on February 13. In this second study, says Dr. Cheng, They plan to give 6,000 mg/day and 12,000 mg/day per day for moderate and severe cases. We are also communicating with other hospitals about starting more intravenous vitamin C clinical studies. We would like to see oral vitamin C included in these studies, as the oral forms can be applied to more patients and at home. Additional information can be found at:

On Feb 21, 2020, a third clinical trial for intravenous vitamin C for COVID-19 was announced:

In addition, Vitamin C is now being used to prevent and treat COVID-19 in China and in Korea. And it is working.

Here is a verified official statement from Chinas Xian Jiaotong University Second Hospital:On the afternoon of February 20, 2020, another 4 patients with severe coronavirus pneumonia recovered from the C10 West Ward of Tongji Hospital. In the past 8 patients have been discharged from hospital[H]igh-dose vitamin C achieved good results in clinical applications. We believe that for patients with severe neonatal pneumonia, and for critically ill patients, vitamin C treatment should be initiated as soon as possible after admission. Numerous studies have shown that the dose of vitamin C has a lot to do with the effect of treatment. High-dose vitamin C can not only improve antiviral levels, but more importantly, can prevent and treat acute lung injury (ALI) and acute respiratory distress (ARDS).

Here is a report from Korea:At my hospital in Daegu, South Korea, all inpatients and all staff members have been using vitamin C orally since last week. Some people this week had a mild fever, headaches and coughs, and those who had symptoms got 30,000 mg intravenous vitamin C. Some people got better after about two days, and most had symptoms go away after one injection. (Hyoungjoo Shin, M.D.)

It is now the official recommendation of the government of Shanghai, China that COVID-19 should be treated with high amounts of intravenous vitamin C.(

Dr. Cheng discusses a case study in which vitamin C was successful against COVID-19 in a family of six at

Passwater: It appears that Dr. Cheng is getting the message about vitamin C and the nutritional need for keeping the immune system optimally functional out to the Chinese people.

Saul: Yes. The photo in Figure 2 is verification of this. The photo is from a DSM announcement on Facebook in February. It shows a truck loaded with 50 tons of vitamin C from the DSM plant in Jiangshan to be delivered to the people of the Province of Hubei of which Wuhan is the capital.

Passwater: 50 tons!

Saul: Yes, 50 tons! The translation of the banner on the truck is In the fight against N-CoV, the people of DSM Jiangshan and Wuhan are heart to heart.

Passwater: What are the recommendations made in the OMNS press releases?

Saul: As therapy for hospitalized patients in China, at least 12,000 to 24,000 mg/day intravenous vitamin C.

For prevention, the physicians of the Orthomolecular Medicine News Service Review Board recommend the following:

Also recommended are:

Nutritional supplements are not just a good idea. For fighting viruses, they are absolutely essential. There is additional information on this at

Passwater: Where can physicians find the specific IV formula to use?

Saul: Physicians can make the vitamin C IV solution themselves by following Dr. Robert F. Cathcarts instructions, which can be found at Any compounding pharmacy can prepare it. Any hospital pharmacy can prepare it. And dont let them try to tell you they cant. May I add a commonsense but important caution to your readers that intravenous or intramuscular vitamin C should only be administered by a licensed health professional.

Passwater: Such a clinical trial cant cost much, and the results would be seen quickly. Drug companies have no interest in studying an unpatentable nutrient, but couldnt the government or a university be willing to test this inexpensive and readily available nutrient?

Saul: Some already are. For example, Professor Qi Chen, Ph.D., and Professor Jeanne Drisko, M.D., both of the Kansas University Medical School, are actively interested in this matter.

Atsuo Yanagisawa, M.D., Ph.D., Professor of Clinical Medicine at the Kyorin University School of Health Sciences, states: Patients with acute viral infections show a depletion of vitamin C. Such patients should be treated by adding vitamin C, via oral or IV, to neutralize free radicals, maintain physiological functions, and enhance natural healing. The Japanese College of Intravenous Therapy [JITC] recommends that our 850 physician members stock extra vitamin C vials in case of a pandemic. JCIT recommends intravenous vitamin C (IVC) 12,000 mg to 25,000 mg for acute viral infections. IVC is usually administered once or twice a day for 2-5 continuous days. To read the complete JCIT protocol in English:

There is no need for delay. The recently passed federal Right to Try act makes it possible for patients to demand unapproved treatments now, and safeguards hospitals and physicians who provide them.

Passwater: Many of our readers are familiar with the publications of physicians such as Fred Klenner, M.D., against polio. Please tell our readers about the teachings of others including Dr. Cathcart. What other conditions should be treated with high-dose vitamin C?

Saul: Virtually all viral illness is treatable with adequately enormous quantities of vitamin C. Over time, as his experience as a physician continued, Dr. Robert Cathcart actually stopped using viral disease names. He just called this viral illness a 60-gram (60,000 mg) cold and that one a 150-gram (150,000 mg) cold. Treatment was based on the amount of C that cured the illness. That is medical brilliance.

Although the most effective dose is truly high, even a low supplemental amount of vitamin C may help save lives. This is very important for those with low incomes and few treatment options. For example, in one well-controlled, randomized study, just 200 mg/day vitamin C given to the elderly resulted in improvement in respiratory symptoms in the most severely ill, hospitalized patients (5). And there were 80% fewer deaths in the vitamin C group. But to best build up our immune systems, we need to employ large, orthomolecular doses (7).

Wikipedia actually deleted existing well-referenced biographical pages of both of these historically important 20th century physicians, Frederick Robert Klenner, M.D., and Robert Fulton Cathcart III, M.D. Over decades of practice and reported in medical journals, both doctors used very high doses of vitamin C to cure serious viral illnesses. It is a moral outrage that in a time of viral emergency, physicians professional opinions, and indeed all information about those physicians therapies, is being kept from the public.

Passwater: Is there suppression of this information?

Saul: Yes. The World Health Organization (WHO) has met with Google, Facebook and other information-access purveyors specifically to stop the spread of alternative health care information about COVID-19. Anyone saying that vitamin therapy can stop coronavirus is already being labeled as promoting false information and promulgating fake news. Even the sharing of verifiable news and direct quotes from credentialed medical professionals is being restricted or blocked on social media. You can see sequential examples of this at I am glad to have this opportunity to share this information with your readers.

Passwater: Its our moral duty to inform and educate. Our readers have a right to know the facts. Thats why I was awarded the Zenger Award for Press Freedom in 2004. Where can readers find more information on vitamin C and viruses?

Saul: The best way is to look at the exact treatment plans doctors are employing, right now, in China. Go to those actually doing it. When I was a boy, my father told me, Andrew, when you want to know something, ask the organ grinder, not the monkey. Instructions by physicians who are experienced with high-dose vitamin C treatment of viral diseases are the most helpful resource on the internet. Detailed protocols are posted for free access at (IV vitamin C); (vitamin C and additional nutrients); and (oral high dosing of vitamin C).

Passwater: I also recommend readers read the article by Drs. Nabzdyk and Bittner (8). Dr. Saul, thank you for educating our readers once again.


Read more:
Vitamin C and the Immune System: Nutritional Fortification to Support Defenses Against Viruses - WholeFoods Magazine

Recommendation and review posted by Alexandra Lee Anderson

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