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Category : Human Longevity

Longevity and Anti-Senescence Therapy Market 2021 Size, Status and Global Outlook Acorda Therapeutics, Calico Life Sciences, Human Longevity Inc.,…

Longevity and Anti-Senescence Therapy Market Growth 20202027 is the latest updated report announced by Oneup Business Insights which is a complete research study on the market, which attempts to provide a clear picture of the key factors that shape this market.

This marketplace additionally analyzes the marketplace status, share, demand, boom rate, destiny trends, marketplace drivers, opportunities, and challenges, dangers and access barriers, income channels, and vendors with the assistance of SWOT evaluation and Porters Five Forces Analysis. In this bit of the research the organizations chief outlines, monetary outlines, and field-tested strategies are introduced.

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Market trends and dynamics supply and demand

Market sizing, growth & estimates considering current trends/opportunities/challenges

Competitive landscape

Technological breakthroughs

Value chain and stakeholder analysis

Top Key Vendors of Longevity and Anti-Senescence Therapy Market Report:

Acorda Therapeutics, Calico Life Sciences, Human Longevity Inc., Insilico Medicine, Oisin Biotechnology, Proteostasis Therapeutics Inc., Recursion Pharmaceuticals, Restorbio, Senex Biotechnology, Senolytic Therapeutics, and Sierra Sciences LLC

Segmentation of Longevity and Anti-Senescence Therapy Market:

Product Type Coverage

Hemolytic Drug Therapy

Gene Therapy

Immunotherapy

Other Stem Cell Therapies

Application Coverage

Hospital

Medical Service Institution

Drug and Device Sales

Regions covered in the Longevity and Anti-Senescence Therapy market report are:

North America

Europe

Asia Pacific

Latin America

The Middle East and Africa

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Table of Contents: Longevity and Anti-Senescence Therapy Market:

Chapter 1: Overview of Longevity and Anti-Senescence Therapy Market

Chapter 2: Global Longevity and Anti-Senescence Therapy Market Status and Forecast by Regions

Chapter 3: Global Longevity and Anti-Senescence Therapy Market Status and Forecast by Types

Chapter 4: Global Longevity and Anti-Senescence Therapy Market Status and Forecast by Downstream Industry

Chapter 5: Longevity and Anti-Senescence Therapy Market Driving Factor Analysis

Chapter 6: Longevity and Anti-Senescence Therapy Market Competition Status by Major Manufacturers

Chapter 7: Major Manufacturers Introduction and Longevity and Anti-Senescence Therapy Market Data

Chapter 8: Upstream and Downstream Longevity and Anti-Senescence Therapy Market Analysis

Chapter 9: Cost and Gross Margin Analysis of Longevity and Anti-Senescence Therapy market

Chapter 10: Marketing Status Analysis of Longevity and Anti-Senescence Therapy market

Chapter 11: Longevity and Anti-Senescence Therapy Market Report Conclusion

Chapter 12: Longevity and Anti-Senescence Therapy Market Research Methodology and Reference

Research Objectives of this report:

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Longevity and Anti-Senescence Therapy Market 2021 Size, Status and Global Outlook Acorda Therapeutics, Calico Life Sciences, Human Longevity Inc.,...

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First AMR Preparedness Index finds UK, US top charts amid first world failures to address antimicrobial resistance threat – Homeland Preparedness News

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A new report from the Global Coalition on Aging (GCOA) and the Infectious Diseases Society of America (IDSA), a first of its kind known as the AMR Preparedness Index, provides an evaluation and roadmap for the 11 largest global economies and their efforts to tackle rising cases of antimicrobial resistance.

While recognition of the threat has risen, according to the organizations, there has been a broad failure to match public promises and actual actions to avert a crisis. The U.K. and the United States have fared best along with Brazil, Canada, China, France, Germany, India, Italy, Japan, and South Korea. Case studies were presented from Australia, Kenya, Russia, Saudi Arabia, and Sweden as well.

Increasing resistance to life-saving antimicrobials, together with our broken innovation pipeline, threatens to erode the very foundation of modern medicine and, with it, erase one of the principal achievements of the 20th century the miracle of human longevity, Michael Hodin, CEO of the GCOA, said. As the United Nations (UN) and World Health Organization (WHO) Decade of Healthy Ageing brings greater attention and energy to our remarkable demographic achievement and the COVID-19 experience make clear the compounded risk to older adults from infectious disease, we must fully acknowledge the threat that AMR poses to the very prospect of healthy and active aging. Without true action to effectively address AMR, tens of millions of lives both young and old will be cut short, and so many others will be diminished as a result of care foregone over concerns about now untreatable infection.

It is estimated that 700,000 people die each year from drug-resistant infections, and those figures are expected to grow as the problem worsens. Resistance is increasing to existing drugs, increasing the risk of even routine medical care.

If unaddressed, the continued rise of AMR is expected to lead to as many as 10 million deaths per year, disability and lower quality of life for millions more, and $100 trillion in lost GDP by 2050, the organizations said in a statement.

Countries were ranked based on seven categories. The results led the GCOA and IDSA to recommend several means of bolstering government action, as well, including:

The COVID-19 pandemic has made painfully clear to all the far-reaching impact of untreatable infectious diseases across societies and economies, Dr. Barbara Alexander, IDSA president, said. As we enter the next stage of the pandemic and with global momentum for AMR action building among G7 countries in the UK with the launch of the subscription pilot, and most recently, with the reintroduction of the PASTEUR Act in the US Congress the 2021 AMR Preparedness Index comes at a pivotal moment. We are pleased to partner with the Global Coalition on Aging to create this vital tool that will help governments around the world reinforce their words with actions.

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First AMR Preparedness Index finds UK, US top charts amid first world failures to address antimicrobial resistance threat - Homeland Preparedness News

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What if marmosets lived on the Moon? – The Economist

Jul 3rd 2021

CAIRD COLLECTIVE, LUNA

Editors note: This year What If?, our annual collection of scenarios, considers the future of health. Each of these stories is ction, but grounded in historical fact, current speculation and real science. They do not present a unied narrative but are set in dierent possible futures

THEY CAN, at times, look somewhat sinister, their faces oddly small for their heads, their white ear tufts jutting out almost aggressively. Their ability to throw themselves at people across seemingly unfeasible distances can be unsettling, and their buzzing and shrieking takes a lot of getting used to, as does their smell. But the members of the Caird collective will not hear a word spoken against the marmosets with whom they share their spaces at the Moons South Pole. As they sit in their insulated caves hoovering moondust out of the animals tails, few of the Cairders can imagine their life on the rim of Shackleton crater without themand none wants to. The marmosets of the Moon are the first and best example of what has turned out to be a fundamental fact of space flight: that the further humans get from Earth, the more they benefit from the companionship of other Earthly animals.

The marmosets were originally brought to the Moon as unwilling participants in a vital research project. Marmosets are lighteven under Earth gravityand reasonably easy to care for, but they have placentas much more like those of humans than any other animal their size, and reasonably short gestation periods. That made them ideal for looking at a fundamental question: can humans have healthy pregnancies in the low gravity of the Moon, where things weigh only one-sixth what they do on Earth?

In the 2020s and 2030s, the years of what the novelist Wil McCarthy called the Rich Mans Sky, questions of obstetrics and gynaecology received remarkably little attention. For many, the idea of staying in space long enough for such things to matter made little sensespace stations in Earth orbit and bases on the Moon were places for fixed-length work contracts and research sojourns, or for tourism. Babies were no more of an issue than they were in isolated 20th-century Antarctic research outposts.

There were, as it happens, a few babies born in Antarctica even back then, when its ice cover was all but intact. The Argentine and Chilean governments both saw the creation of natives on the continent as a way to establish sovereignty and arranged births to that end. But there was no reason to think that Antarctica was inimical to pregnancy and infancy. The long-term health effects of low gravity and microgravitywhich for those in orbit include brittle bones, muscle wasting and eye diseasewere something else. Adults could counter some of these effects with treadmills and tension cords. But as the title of an early paper on the subject succinctly put it, The fetus cannot exercise like an astronaut.

Even those, like Elon Musk, who talked of permanent settlements on Mars spent little time working on the question. It was left to a small team of scientists in the Japanese modules of the Artemis base founded in 2029 by America and its allies to explore the question experimentally with the help of marmosets, gene-splicing technology, intra-uterine monitoring devices and a giant centrifuge.

They had some success. Like human fetuses, marmoset fetuses spend most of their gestation with a density equal to that of the amniotic fluid around them, a neutral buoyancy that leaves them indifferent to local gravity; only relatively late on do differences due to gravity start to crop up. After a few years of trial and error, and some dainty gene-editing to rebalance the rate at which bones grow when not stressed through use, the researchers developed a regime involving hormone treatments for the mothers and regular late-pregnancy sessions in their custom-made room-sized centrifuge, known as the marmo-go-round. This reliably produced pups with strong-enough bones and muscles and little by way of deformity, though their tails were impressively long even by marmoset standards.

Unfortunately, in 2038 that research was interrupted by the geopolitical meltdown of the wolf-and-wimp war and then by the 26 months of the Great Grounding. With all powered flight within or through the Earths atmosphere prohibited, the various Moon bases seemed doomed even after they agreed to pool their resources to create what became known as the Polynational James Caird Collective. With all the groups biotech know-how turned to increasing food production and nutrient recycling, the marmosets were at first ignored and then freed to roam within the bases. Their effect on morale was instantaneous and profound.

The importance of companion animals to the mental health of people engaged in a homeless lifestyle was well documented in pre-war societies. It has been suggested that the effect of the marmosets on the Caird collective was similar; cut off from Earth, the humans were more homeless than any group of people had ever been before. Caring for, playing with and grooming marmosets also became a basis for bonding between humans, many of whom had not known each other before the Grounding, and some of whose countries had been adversaries in the war. By the time the mysterious entity responsible for the Great Grounding finally abandoned its control of the Earths air-traffic-control and missile-defence systems, allowing traffic with the Moon to resume, the marmosets had become an indispensable part of the settlers new identity and society. Few believe that a lack of companion animals was, in itself, the reason that the Mars base failed during the Grounding. But it surely did not help.

The bond between the Moons larger and smaller primates persisted even as the rigours of separation came to an end. Almost all Cairders still dislike spending any significant time deprived of marmoset company. They cuddle them and relish their low-gravity acrobatics. In a joking way that seems, at some level, not to be a joke, they treat the abnormally long tails of the Moon-born marmosets as a sign of providence, holding the tail-fur to be particularly good at picking up moondust. The dust, which can cause lung disease, infiltrates their habitats despite all the airlock precautions; its suppression is a constant battle. Whether hoovering it out of tails which accumulate it in the manner of a feather duster is in fact more effective than the settlements electrostatic air-filtration systems is open to question. But it is clearly more therapeutic. And the marmosets enjoy the attention.

The oldest Earth-born marmoset, New Mrs Chippy (who is, despite his name, male) enjoys an honorary seat on the collectives council. He has now reached the age of 31 with no obvious signs of ageing other than a pelt almost as white as his ear tufts. This is seen as a good omen for human longevity among those Cairders who refuse to countenance a return to Earth. In Japan, by contrast, laboratory marmosets rarely make it past their 21st birthday.

The most salient biological, as opposed to sociological, novelty among Moon-born marmosets is a very high prevalence of adolescent-onset blindness. The constellation of eyesight problems known as Spaceflight Associated Neuro-ocular Syndrome (SANS) has been studied since early this century. In adult humans SANS normally develops only during long stays in the microgravity conditions of space stations; it is rare and mild among humans on the Moon. But in marmosets born in low gravity it develops swiftly and severely at the onset of puberty and leads to almost complete loss of vision.

There is as yet no agreed explanation for this pathology. Some researchers believe it is not in fact gravity-related but the result of an off-target effect of the gene editing which realigned the calcium pathways used in bone growth, but it is hard to square this with the similarity to SANS as experienced by genotypical adult humans. Others think its onset could be avoided if newborn pups were required to spend more, or all, of their time in the simulated Earth-normal gravity of the centrifuge. But it has proved hard to test this hypothesis. Infants that have spent any time at all in lunar gravity are greatly distressed by the rigours of the centrifuge and will not suckle when put into it. And Cairders are unanimous in their opposition to anything that causes marmosets distress.

The blind marmosets are not badly off. Their sibling groups and human companions provide what little practical support they need. And they are happier than sighted marmosets to travel in the pouches which many Cairders have incorporated into the suits they use for working on the lunar surface. Sighted marmosets are clearly disturbed by the harsh monochrome landscape, even when emotionally supported with the amplified sound of their companions heartbeat.

Sudden-onset SANS leaves the question of whether human children can be born and raised on the Moon unanswered. It is sometimes suggested that a blind woman happy with the idea of a child who might also be blind could choose to join the collective and explore the issue. But bringing a child to term would require a centrifuge capable of holding a grown human, rather than a 250-gram marmoset. There is no appetite among Cairders for devoting resources to such a project, and their juche ethic of self-sufficiency will not let them accept funding for such experiments from Earth. Thus how well humans may eventually be able to breed on alien worlds remains unknown, even today.

That they will take animal companions with them, though, now seems certain. And some of those companions will surely have shocking-white ear tufts, odd little faces and very long tails.

Full contents of this What If?Freedom to tinker, October 2029: What if biohackers injected themselves with mRNA?The other epidemic, June 2025: What if America tackled its opioid crisis?A tale of two cities, June 2041: What if a deadly heat wave hit India?You are what you eat, January 2035: What if everyones nutrition was personalised?iHealthy, September 2028: What if smartphones become personal health assistants?Mrs Chippys benediction, February 2055: What if marmosets lived on the Moon?*Novel treatments, August 2050: What if dementia was preventable and treatable?Rage against the machine, December 2036: What if an AI wins the Nobel prize for medicine?Germ of an idea: What if germ theory had caught on sooner?

This article appeared in the What If? section of the print edition under the headline "Mrs Chippys benediction"

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What if marmosets lived on the Moon? - The Economist

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Quote Of The Week: Zach Bush MD On World Microbiome Day – Longevity LIVE – Longevity LIVE

Zach Bush MD, is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems. Celebrating World Microbiome Day on 27th June 2021, he explained why theres no better time to pay tribute to the microbiome.

As human beings, our neurologic capacity begins with our connection to the microbiome Zach Bush MD

In his latest weekly newsletter, Bush said, It is, in its entirety, vital to life and the reason why we are here today. Without the microbiome, life on Earth would not exist.

At its most basic definition, micro means small, and biome means living creatures essentially all of the living microbes on and inside the human body. Today, we know human cells are not at the foundation of the human microbiome, but rather its the fungi and bacteria that are. It is estimated that we have 50 to 70 trillion human cells, which pale in comparison to the 1.4 quadrillion bacteria and 10 quadrillion fungi inside our bodies.

He explained further that as we learn more about the microbiome and our human biology, its clear that this diverse non-human micro ecosystem is what makes life possible. Its what fuels our development, immunity, and nutrition, enabling our production of energy, micronutrients, and regenerative pathways. Within every organ system throughout our whole body, its this unique niche of bacteria, fungi, and yeast that nurture our human cells.

Get out! Kick off the shoes, walk in a garden, on a forest path, a beach, a meadow, or a mountain top. Zach Bush, MD

World Microbiome Day was celebrated on the 27th June. You can read more about it here: #microbiome4life

Zach Bush MD is a physician specializing in internal medicine, endocrinology and hospice care. He is an internationally recognized educator and thought leader on the microbiome as it relates to health, disease, and food systems. Dr Zach founded *Seraphic Group and the nonprofit Farmers Footprint to develop root-cause solutions for human and ecological health. His passion for education reaches across many disciplines, including topics such as the role of soil and water ecosystems in human genomics, immunity, and gut/brain health. His education has highlighted the need for a radical departure from chemical farming and pharmacy, and his ongoing efforts are providing a path for consumers, farmers, and mega-industries to work together for a healthy future for people and planet.

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Quote Of The Week: Zach Bush MD On World Microbiome Day - Longevity LIVE - Longevity LIVE

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Nagy: The president and the tsar – LubbockOnline.com

TIBOR NAGY| Lubbock Avalanche-Journal

Churchill had some brilliant quotes, but his most famous one about Russia a riddle wrapped in a mystery inside an enigma. -- is wrong. Russias self-identified role in the world hasnt been a mystery since Napoleons wars, maybe even earlier: to protect its heartland by extending its control and influence as far as possible in every direction, and to perpetuate the privileges of its ruling class thru all possible means.

Through expansion under a succession of Tsars and Commissars the Russian landmass now covers 11 time zones and exerts influence much farther. While Russias vastness and bitter winters consistently defeated a series of enemies who had no problems overrunning the rest of Europe, its leaders have been less consistent in their capabilities. But its current tsar, President Vladimir Putin, is also one of its ablest understanding fully how to maximize Russias weakened global position. With the end of the Soviet Union in 1991, Russia lost about 25% of its territory, and as recently as 2009 was characterized as Burkina Faso with nuclear arms (meaning its economy relied on the export of natural resources).

But while Putin may be holding a pair of tens, hes playing them like a full house. Added to his mastery of history and geopolitics is his expertise in human behavior gleaned from decades of KGB tradecraft which makes him doubly dangerous as an adversary. He has a near perfect record of opportunistic timing on when/how to strike with calculated impunity: seizing Crimea, saving Assad in Syria, sending combat volunteers into eastern Ukraine, manipulating Western Europe to embrace his Nordstream II natural gas pipeline, winking at cybercriminals who inflict major damage on U.S. infrastructure and morale, and poisoning political opponents when he cant simply arrest and torture them.

But for once, going into a summit with a Russian leader, the U.S. side was represented by a president who himself has long political experience and doesnt suffer from naivete or geopolitical ignorance. The U.S. track record in these meetings has been poor: e.g. Roosevelt giving away Eastern Europe to Stalin and Kennedy coming off so weak to Khrushchev that the Soviets were emboldened to move nuclear missiles to Cuba. (Reagan being an exception who more than held his own against Gorbachev.) There will be thousands of words written analyzing the Biden/Putin Summit, but they matter little. What counts is what measure Putin took away from their meeting because that will determine how Putin will play his pair of tens during Bidens presidency.

Putin will stay as he has - searching for and exploiting whatever weaknesses he detects in the US leadership or the western alliance. He will use every geopolitical weapon he believes he can get away with, pursue the Big Lie as effectively as any Soviet leader ever did, neutralize his opponents with whatever means work, and continue to allow his cronies to amass immense wealth at the expense of his people. Russia is neither a mystery, riddle nor enigma. Russia will simply continue its centuries-long policy of opportunistically and brutally assuring its place in the world and the longevity of its ruling class.

Ambassador Tibor Nagy was most recently Assistant Secretary of State for Africa after serving as Texas Techs Vice Provost for International Affairs and a 30-year career as a US Diplomat.

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Nagy: The president and the tsar - LubbockOnline.com

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Where Is the Endgame in Chess Experts’ Visual Memory Abilities? – University of Texas at Dallas

Chess experts are known for their remarkable ability to recall configurations of chess pieces on a board. For decades, neurological experts have investigated how this memory functions and whether it can be applied to information beyond the gameboard.

To further probe this topic, researchers from The University of Texas at Dallas Center for Vital Longevity (CVL) turned to the UTDallas chess team. Since the chess programs inception in 1996, 24 Grandmasters and International Masters have played for the UTDallas team, which has competed in the Presidents Cup known as the Final Four of College Chess in 17 of the last 21 seasons.

Dr. Chandramallika Basak

The researchers tested 14 chess team members, along with 15 chess novices, on rapid-fire processing of visuospatial information in working memory.

Their findings, published June 14 in Memory and Cognition, help pinpoint the strengths and limitations of the subjects recall framework and how that framework can be applied to human cognition in general.

Prior studies have shown that chess experts advantage in visual memory is limited to chess pieces on chess boards, said corresponding author Dr. Chandramallika Basak, associate professor of psychology in the School of Behavioral and Brain Sciences. We wanted to see whether the expertise generalizes beyond chess pieces to unfamiliar, new stimuli, and where does this expertise break down for immediate memory.

Chess masters visual short-term memory for arrangements that can occur in chess has been of particular interest to cognitive scientists, said Basak, director of the Lifespan Neuroscience and Cognition Laboratory.

Its almost like chess experts have snapshots of these positions they demonstrate remarkable visuospatial working memory, given that the information is presented for less than half a second, she said. But is it driven by the visual aspects or spatial aspects of what they saw? Or a combination of both?

Evan T. Smith, a UTDallas cognition and neuroscience doctoral student, is the papers lead author. He described the difference between working and long-term memory as analogous to the gap between whats on top of your desk and whats filed away in a cabinet.

Evan T. Smith

The existing theory is that chess players have so thoroughly memorized and categorized board configurations that their long-term memory for this information functions like working memory, he said.

The researchers collaborated with Jim Stallings, director of the UTDallas chess program, to bring test subjects on board from the team.

Dr. Basaks study varies from other chess studies done with youngsters, Stallings said. This study goes directly to chess expertise and working memory. I look forward to sharing the results with the chess community.

The control group included UTDallas students of similar age and education level to the chess players who had never formally learned how to play chess.

In each test, participants saw a two-dimensional chessboard with a number of pieces displayed for three-tenths of a second. After a one-second pause, they saw a second chessboard and had to decide if there had been a change.

The tests were conducted with standard chess pieces and with novel, unfamiliar symbols. Basak said that this switch helped to determine if the chess players memory abilities were domain specific to chess or domain general to a wider range of objects.

One series of tests asks about changes in location; the second asks if the objects the pieces themselves have changed, Basak said. A third test incorporates changes in location or changes in object, or both, or no change at all. Finally, the grid of the board is removed.

The researchers found that while both chess experts and novices performed better with chess stimuli than with the unfamiliar symbols, the experts, for the most part, outperformed the control group for both chess stimuli and for the new objects particularly when detecting positional changes.

Section A of this figure from the Memory and Cognition article shows how each trial works: An initial configuration appears for three-tenths of a second, followed by a one-second pause. The three different trial types then could change an objects identity, location, or both. Section B shows the chess stimuli and novel stimuli used. Section C shows a trial with the grid removed.

When changing the identity of the objects, however, but not location, the chess players advantage was limited to the chess pieces. They performed no better than the control group at remembering when the identity of the novel symbols changed.

You would expect that this advantage that chess players have is related to a familiarity with the chess pieces or the chess players expectation of what they are about to see, Basak said. But results from our study say otherwise. It seems like the chess players can rapidly process a chessboard-like layout in a very holistic manner, like the brain does with faces. The next step in our research may be to do a functional MRI study to see if the face-processing regions of the brain are also used for chess.

The experiments also were split into tests using fewer than four pieces which is within the normal limits of an average persons focus of attention and five to eight pieces. With the larger number of pieces, long-term memory should come into play. The chess experts performed better than the controls in the tests with more pieces.

We observed an eight-item working-memory capacity for chess experts, Basak said. We assume that ties back to the idea that chess players are viewing the board and the set of positions as a single object, as they would recognize a face.

The grid-versus-no-grid portion of the study something that Basak said has not been examined before produced some of the more striking results.

The grid is the linchpin that supports the scaffolding of this memory structure, Smith said.

Basak added: Any expertise-related advantage disappeared in the absence of the chessboard display. It appears to be essential, acting as a road map, a familiar framework to aid the memory.

Collectively, the results indicate that visuospatial memory advantages associated with chess expertise extend beyond chess stimuli in certain circumstances, particularly to position changes with between five to eight items. But the grid appears to be necessary for experts to leverage these advantages.

We cannot generalize our findings beyond what we tested, so we cannot claim, based on our data, that chess experts will be better at studying for school, Basak said. But their advantage does go beyond chess pieces, provided the grid remains. We believe this indicates that experts are automatically encoding spatial-relational information.

Other contributors to the research were Dr. Daniel Krawczyk, UT Dallas professor of psychology, holder of the Debbie and Jim Francis Chair in Behavioral and Brain Sciences, deputy director of the Center for BrainHealth and associate professor of psychiatry at UT Southwestern Medical Center; and Dr. James Bartlett, a distinguished scholar in cognitive neuroscience and cognitive psychology and a longtime UTDallas faculty member who played a key role in the beginning of the project. Bartlett died in 2019.

Jim Bartlett played a big role in designing the experiments and in bringing Jim Stallings and the chess team on board, Basak said. He was a mentor, friend and valued collaborator, and we dedicate this publication in honor of his memory.

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Where Is the Endgame in Chess Experts' Visual Memory Abilities? - University of Texas at Dallas

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REVIEW: ‘The Dig’ is captivating, beautiful exploration of past The Daily Free Press – Daily Free Press

Combining the directorial skills of Simon Stone, the screenplay adaptation by Moira Buffini and the cinematography of Mike Eley, The Dig portrays a dynamic, true story intertwining themes of history and modern existential longing with dramatic scenes concerning life, death, love and family.

The Netflix film, released Jan. 29, is an adaptation of John Prestons 2007 novel of the same name and is based on a true story. Taking place in the rustic countryside of Suffolk, England on the eve of World War II, self-taught archaeologist Basil Brown, played by Ralph Fiennes, embarks on a dig to uncover whats believed to be ancient Anglo-Saxon ruins potentially dating as far back as the Vikings or further.

The site lies on the vast estate owned by Edith Pretty, played by 2013s The Great Gatsby star Carey Mulligan. Pretty is a widow left with one son and a dream to dig up three large, grassy, hill-like mounds located in the fields. Though the archaeologist is unconvinced theres anything significant to be found, attempted grave robberies have convinced Pretty theres something extremely valuable hidden within.

Brown, a local archaeologist with the Ipswich Museum, leads the Sutton Hoo excavation, with Peggy Piggott, played by Lily James. Hes portrayed as a modest working man with vast knowledge of the land. His soil expertise is what leads Pretty to hire him in the first place.

Given the politics of the time period, the dig site is seen as an area of national interest as Britain was preparing to protect the countrys ancient ruins from German air raids.

The story shifts toward a more intimate focus, concerned with family and belonging, when Prettys young son Robert, played by Archie Barnes, grows increasingly fond of Brown. The two are portrayed almost as father and son, bringing the narrative closer to one of community rather than national glory.

The Dig captures a unique perspective of existentialism, with the story taking place during Britains mobilization before wartime. It keeps audiences reflecting on the significance of human legacy, wondering what will be left of us after we are gone.

As the characters on screen are forced to come to terms with their own mortality in an age of destruction and uncertainty, we get a better understanding of the significance of these ancient runes that are still standing a testament of humanitys longevity.

Aside from matters of historical and ancestral significance, The Dig is a nod to the struggles that affect ordinary people of today, with overtones of love, lust and heartbreak.

What keeps viewers satisfied throughout the film is the unchanging and breathtaking scenery of the Suffolk countryside. Eley yields cinematographic mastery by capturing the lush wheat fields of eastern England, combined with enticing pan shots of the site to emphasize how massive this project is, yet also how seemingly small of a role it plays in the full history of the nation.

Stone keeps audiences holding their breaths by turning a story of national history into a heartfelt drama that so accurately touches on struggles that afflict people of all backgrounds.

Its worth mentioning the film has received some criticism for sexist portrayal of characters, for ageism despite the whimsical setting and for fictionalizing some of the truth.

Be that as it may, it was worth the watch.

At surface level, The Dig seems like a story of historical drama, but it takes audiences into deep-cutting, emotionally luring instances of love, loss, triumph and human connection.

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REVIEW: 'The Dig' is captivating, beautiful exploration of past The Daily Free Press - Daily Free Press

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Study examines why college education leads to healthier and longer lives – William & Mary News

Healthy lifestyle: Physical activities abound on college campuses like William & Mary. These healthy habits are among the benefits of college education that contribute to health and longevity, according to a study led by W&M Assistant Professor of Economics Peter Savelyev. Photo by Jim Agnew

by Nathan Warters | February 4, 2021

A study led by William & Mary Assistant Professor of Economics Peter Savelyev and funded by the National Science Foundation argues that college education leads to healthier and longer lives.

The study, Understanding the Mechanisms Linking College Education with Longevity, was published in September in Journal of Human Capital.

Researchers around the world still debate whether education affects health. Savelyev and his team support the claim that education improves heath by demonstrating the mechanisms behind this effect while using state-of-the art statistical analysis.

In our paper, we show that education increases health and longevity though healthier lifestyles, superior earnings and better work conditions, he said.

Savelyev and his co-authors examined data obtained from men and women who graduated from high school in Wisconsin in 1957. This specific timeframe was important to allow for data collection on at least a partially deceased U.S. cohort.

William & Mary News recently spoke to Savelyev about this study. The interview has been edited for length and clarity.

Variables related to healthy lifestyles that proved to be important are participating in physical exercise, maintaining a healthy body weight and abstaining from smoking tobacco. We also study the role of extremely dangerous work conditions, such as cutting trees or being exposed to infectious diseases. Educated people are less likely to face such jobs. The work conditions mechanism does not necessarily imply diminishing job-related risks for the general population, but it is a personal benefit for those who study hard and receive advanced degrees.

It is well known that many essential life determinants emerge early in life. Later in life, things are harder to change. College education is a powerful contributor to human development that increases health and longevity, among many other good effects, and it should be supported in situations when free market solutions do not work well enough.

Our simulations demonstrate that major health differences created by college education are hard to close later in life, even by strong hypothetical policy interventions, such as greatly increasing taxation of cigarettes.

Partly, this is because the effect of education is strong, and it works through many different mechanisms. It is not easy for an intervention that targets just one specific mechanism to overcome a strong effect created through dozens of mechanisms. Also, some policies, such as taxation of cigarettes, affect behavior of both the college-educated and those who did not go to college, so the effect on the difference between these two groups is small.

We find that obtaining a bachelors degree leads to about three additional years of life for men. However, we could not find any effect of college education for women, who live longer than men regardless of their education status. We identified from our data two mechanisms that partly explain the gender difference. One is that men tend to take more dangerous jobs than women. Another is that educated women of this historic cohort born in late 1930s in Wisconsin were less likely to be married, which created a negative contribution to their longevity that masked a positive contribution related to higher income. Marriage is good for your longevity. Since a negative effect of college education on marriage no longer takes place for more recent cohorts of women, we can expect a stronger effect of college on their longevity, as confirmed by our simulations.

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Study examines why college education leads to healthier and longer lives - William & Mary News

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Appointments, honors and activities – Purdue News Service

Thanos Tzempelikos, professor in the Lyles School of Civil Engineering, has received the prestigious Leon Gaster Award from the Society of Light and Lighting as a co-author of the paper, "Cross-validation and Robustness of Daylight Glare Metrics." This award is presented annually, naming the best paper of the year concerned with lighting applications. The award was presented at the societys Annual Awards evening in December in London.

Dr. David Waters is the recipient of the Center on Aging and the Life Course's (CALC) Outstanding Professor Award.Waters is professor emeritus in the College of Veterinary Medicine and a CALC faculty associate. Waters teaches biology of aging and received numerous student nominations for the award, which recognizesexceptional teaching and mentoring of emerging scholars in aging. He is director of the Center for Exceptional Longevity Studies at the Gerald P. Murphy Cancer Foundation.

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Orr Fellowship, a postgraduate professional development program based in Indianapolis, has recently selected four Purdue seniors as Orr Fellows. The Orr Fellowship is one of Indianas most celebrated nonprofit talent programs. The students Miguel Diaz, Sean ODell, Eleanor Hamilton and Hannah Vanderbosch were chosen out of nearly 1,300 applicants and will begin at one of 46 Orr Fellowship partner companies upon graduating in May. They also will participate in Orr Fellowship programming dedicated to nurturing entrepreneurship and developing strong leadership skills.

Christine McCall, a graduate research and teaching assistant in the College of Health and Human Sciences, earned a top honor from the National Council on Family Relations for a paper. McCall won the Outstanding Student and New Professional Paper Award for her paper titled A Part of Our Family? Effects of Psychiatric Service Dogs on Quality of Life and Relationship Functioning in Military-Connected Couples.

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Appointments, honors and activities - Purdue News Service

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Around Town: UC Irvine to host a virtual celebration Monday to ring in the Year of the Ox – Los Angeles Times

The Lunar New Year will be welcomed Monday afternoon when UC Irvine hosts a special virtual celebration of the Year of the Ox.

The festivities are free and open to the public and are expected to include a dragon dance and feeding of the lion in addition to performances from artist Abigail Washburn and world-famous guzheng musician Wu Fei.

There will also be a virtual wishing tree and guests will be able to make a wish for prosperity, happiness and longevity by writing a wish on a red wishing card and taking a selfie with it. Wishing cards and more details on the event can be read at humanities.uci.edu.

Registration is required to attend and the event will begin at 4:30 p.m. on Feb. 8.

The Lunar New Year is on Feb. 12.

Laguna Beach hires recruiting firm for city manager searchLaguna Beach has begun the recruiting process in search of the seaside communitys next city manager.

John Pietig, the presiding city manager of Laguna Beach, announced the first week of January that he plans to retire in June. His service to the city has spanned 20 years.

The Laguna Beach City Council, which makes the appointment for the position of city manager, has hired the recruiting firm Bob Murray & Associates to carry out a search for candidates to serve as the citys top executive. City officials said the estimated cost for the executive recruiting firms services is less than $30,000.

This is one of the most important positions in the city, and hiring the recruiting firm will allow us to thoroughly evaluate both internal and external candidates for the City Manager position, Laguna Beach Mayor Bob Whalen said in a statement.

Pietig began his run with Laguna as assistant city manager, and he has served as city manager for the last decade. According to Whalen, the City Council aims to name his replacement in May.

Laguna Beach Dems to host OC Supervisor race talk Attorney Ashleigh Aitken will address the 6:30 p.m. Feb. 10 meeting of the Laguna Beach Democratic Club, a Zoom meeting that is open to the public. The events topic is the upcoming Orange County Board of Supervisors election, what role the board plays in running the county and how it allocates its $7.5 billion budget.

We should all be informed about and weigh in on how our tax dollars are being allocated by the Board of Supervisors, Gwen McNallan, president of the club, stated in a news release.

To learn more about the club, or to register for Wednesdays Zoom meeting, visit thelbdems.com.

OC emergency rental assistance program accepting applicationsThe County of Orange is accepting applications through the month of February for an Emergency Rental Assistance program for eligible renters struggling with unpaid rent or utilities bills during the COVID-19 pandemic.

Launched this week and funded by a $65.5 million allocation from the U.S. Department of Treasury, the program aims to provide financial assistance to those whose combined household income is at or below 80% of the countys average median income.

In Orange County, the median income is approximately $71,750 for an individual, $82,000 for a two-member household, $92,250 for three people and $102,450 for a four-person household. For more information on household size, visit era.211oc.org.

Residents of Anaheim, Santa Ana and Irvine may not participate in Orange Countys assistance program, as those cities have population sizes over 200,000 and maintain their own local city programs, according to a release issued last week by the Orange County Health Care Agency.

The Emergency Rental Assistance program does not apply to homeowners with past-due mortgage payments, utilities or energy costs. Funds may only be granted to renters.

Applicants will need to provide a photo ID, a copy of their lease agreement, proof of income affected by COVID-19, such as an unemployment letter or a letter from an employment detailing reduced hours or pay and proof of unpaid rent or utilities, such as documentation from a landlord or utility company stating an amount owed or overdue.

To learn how to apply, call 2-1-1 to receive assistance in multiple languages, visit era.211oc.org or text ERA to 898211.

Marine Corps Scholarship Foundation accepting applications through March 2A range of college scholarships are available to children or stepchildren of a Marine or Navy corpsmen, chaplain or religious programs specialist attached to a Marine unit who have a cumulative grade point average of 2.0 (on an unweighted 4.0 scale) and whose family has an adjusted gross income of $106,000 or less for 2021-22.

Scholarships are available for those pursuing an associates or bachelors degree, attending or planning to attend a college or career training school listed on the National Center for Education Statistics College Navigator website during the 2021-22 academic year.

Career and technical education scholarships are also available for students planning to attend a non-degree certificate program or vocational training 12 months or less at a community college or private career school listed on the College Navigator website.

Applications may be submitted through March 2. For more information, visit mcsf.org/apply.

Laguna Beach Festival of Arts 2021 grant applications due March 5Nonprofit organizations with programs promoting fine arts in and around the city of Laguna Beach are welcome to apply for a series of art grants through the Festival of Arts Foundation beginning Feb. 8.

The Foundation, established in 1989 to preserve and promote fine arts and other artistic endeavors in the area, will be accepting applications through March 5.

The FOA Foundation is proud to be able to assist local non-profit art organizations during these challenging times, Foundation President Bob Earl said in a statement. We hope that these funds will help to continue the programs that educate our community on the importance of art and cultural experiences.

Applications can be submitted online at foapom.com/grants. For information on eligibility, grant awards and the application process, contact Bob Earl at (949) 494-4132.

Laguna Beach school board appoints Michael Conlon to assistant superintendentThe Laguna Beach Unified School District has named Michael Conlon its assistant superintendent of human resources and public communications, according to district officials.

Conlon, who was serving as the director of human resources for the district, was appointed to the role at the board meeting on Jan. 28, at which the board considered reorganizing into a format with three assistant superintendents.

A statement from the district said that the decision would not result in an increase in staff. Jeff Dixon is the assistant superintendent of business services, and the district plans to hire an assistant superintendent of instructional services.

Michael [Conlon] has continued to demonstrate his focus on continuous improvement for himself and our community, District Supt. Jason Viloria said in the release. He is committed to developing positive relationships with staff and problem-solving conflicts when they occur. He has proven to be an effective human resources leader and administrator whose work is characterized by a genuine concern for the entire school community.

Back Bay products Mo Kenney, Tanner Pulice earn mens water polo honorsNewport Harbor High alumnus Mo Kenney earned Mountain Pacific Sports Federation Player of the Week honors this week, while Corona del Mar High product Tanner Pulice was named the MPSF Newcomer of the Week.

Both Kenney and Pulice are freshmen for the UCLA mens water polo team.

In his collegiate debut, Kenney scored a game-high five goals on Jan. 30 to lead the No. 2-ranked Bruins to a 15-9 home win over No. 5 Pepperdine. Four of the goals were even strength, and one came on the power play. He needed just six shots to score the five goals.

Pulice had two goals and two assists in the victory, also winning a sprint and drawing an exclusion.

Cal senior football player Michael Saffell, an Edison High alumnus, has been named the Pac-12 Football Scholar Athlete of the Year.

Saffell, a center, started on the offensive line for the Golden Bears each of the last three years, earning honorable mention All-Pac-12 honors in 2020. He began his career at guard before moving to center as a junior.

Due to COVID-19, he is eligible for a fifth year of competition, and he has opted to return in 2021.

Saffell earned his bachelors degree from Cals Haas School of Business in three-and-a-half years, graduating in December with a 3.62 undergraduate GPA. He was accepted into the universitys Master of Information and Data Science program, which he began in January.

Orange County SC shirt sales to benefit OC Educational Arts AcademyThe Orange County Soccer Club has started the JuntosMsFuertes campaign, hoping to combine the communitys passion for soccer and the arts to support diverse nonprofit organizations.

A custom shirt has been created in collaboration with a local artist, and all net proceeds from its sale will go to the Orange County Educational Arts Academy.

Located in Santa Ana, the institution serves about 630 students, ranging from transitional kindergarten to eighth grade.

Hugo Cesar Chavarria was the Southern Californian artist called upon to create the design for the shirt, which depicts action in an Orange County Soccer Club game with landmarks like the Santa Ana Water Tower and the Great Park Balloon in Irvine in the background.

The shirts are limited edition and will be on sale through February. The cost is $20 per shirt, and they can be purchased at the following link: bit.ly/OCSCDASH.

Sage Hill School accepting applications for 2021-22 school year through Feb. 15Sage Hill School, a nonprofit, non-denominational independent high school is accepting applications for students in grades 9-12 for the 2021-22 school year through Feb. 15.

Having reopened its doors to students in September five days a week, Sage Hill offered classes virtually or in-person during the 2020-21 school year.

For more information on programs, or to apply online, visit sagehillschool.org and click on the Admission tab. For all candidates who apply by the Feb. 15 deadline, first-round decisions will be announced the last week of February.

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Around Town: UC Irvine to host a virtual celebration Monday to ring in the Year of the Ox - Los Angeles Times

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