Page 3«..2345..1020..»

Category : Human Longevity

AgeX Therapeutics Reports First Quarter 2020 Financial Results and Provides Business Update – Business Wire

ALAMEDA, Calif.--(BUSINESS WIRE)--AgeX Therapeutics , Inc. (AgeX: NYSE American: AGE), a biotechnology company developing therapeutics for human aging and regeneration, reported financial and operating results for the first quarter ended March 31, 2020.

The human tragedy of this pandemic has long tentacles that effect numerous businesses including AgeX, said Greg Bailey M.D., Chairman. Given the current global economic landscape, and the changes that businesses will need to make to accommodate to a post pandemic world, we feel that new business model aligns well to be able to function in this new environment. We see enormous opportunity to license and joint venture PureStem and HLA-G while implementing a definitive plan to begin preclinical trials on tissue regeneration under the leadership of Michael West and Michael May. We will update you in the future as these plans progress.

AgeX has completed a company restructuring to help set it up for success in the future. The combination of company priorities, cash position and the COVID-19 pandemic led to employee lay-offs designed to support the evolution of AgeX's current team to execute on strategic business goals going forward and to ensure cash is directed at near-term priorities to deliver maximum shareholder value. AgeX has a dual business strategy to diversify risk and maximize opportunities. It plans to continue to pursue its licensing and collaboration strategy for its two primary technology platforms, UniverCyte immunotolerance technology for the generation of universal cells, and PureStem cell derivation and manufacturing technology for the production of therapeutic cells with potential advantages, including industrial scalability and lower manufacturing costs. Since the launch of its licensing and collaboration strategy in January 2020, AgeX has delivered a research collaboration in Japan focused on developing universally transplantable cells for therapeutic use based on UniverCyte, entered into a neural stem cell therapy research collaboration for neurological disorders utilizing PureStem at a California University, and AgeX licensee ImStem Biotechnology received the first-ever clearance of a cell therapy derived from AgeXs embryonic stem cells by the FDA to enter human studies.

In addition, AgeX remains committed to pursuing in-house cell therapy product development and plans to raise money to build the optimal team to deliver on its products, AGEX-BAT1 for metabolic diseases such as type II diabetes and AGEX-VASC1 for tissue ischaemia. AgeXs budgetary and personnel adjustments will result in the deferral of in-house product development and may also lead to AgeX seeking arrangements with other companies in the cell therapy or biopharma industry for the development of its product candidates and technology, or outsourcing of some of that work to service providers until further funding can be obtained to rebuild in-house research and development staff for one or more of those programs. Development of AgeXs iTR technology may be done at AgeXs subsidiary Reverse Bioengineering, Inc. subject to successful financing of the subsidiary.

Upwards of 80% of healthcare expenditures in the United States relates to chronic degenerative disease and aging is a principle underlying cause of such conditions, said Michael D. West, Ph.D., AgeXs Chief Executive Officer. Therefore, the ability to manufacture to scale young clinical-grade cells capable of regenerating functionality in diverse tissues of the body has the potential to transform healthcare as we know it today. Perhaps even more noteworthy is the potential of reversing developmental aging in the body itself through AgeXs iTR technology. Our goal in the coming year is to advance the development of our intellectual property with the goal of bringing value to our shareholders.

Q1 Highlights

Liquidity and Capital Resources

AgeX is in need of additional capital to finance its operations. On March 30, 2020, AgeX entered into a Secured Convertible Facility Agreement (the New Loan Agreement) with Juvenescence Limited pursuant to which AgeX may borrow funds from time to time. On April 1, 2020 AgeX drew the initial $500,000, and may draw additional funds from time to time subject to Juvenescences discretion, prior to the contractual repayment date on March 30, 2023. AgeX may not draw down more than $1 million in any single draw. More information about the New Loan Agreement can be found in AgeXs Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission on March 30, 2020 and May 14, 2020, respectively.

On April 13, 2020, AgeX obtained a loan in the amount of $432,952 from Axos Bank under the Paycheck Protection Program (the PPP Loan). The PPP Loan will bear interest at a rate of 1% per annum. No payments will be due on the PPP Loan during a six month deferral period commencing on the date of the promissory note. Commencing one month after the expiration of the deferral period, and continuing on the same day of each month thereafter until the maturity date of the PPP Loan, monthly payments of principal and interest will be due, in an amount required to fully amortize the principal amount outstanding on the PPP Loan by the maturity date. The maturity date is April 13, 2022. The principal amount of the PPP Loan is subject to forgiveness under the PPP to the extent that PPP Loan proceeds are used to pay expense permitted by the PPP, including payroll, rent, and utilities (collectively, Qualifying Expenses), during the time frame permitted by the PPP. AgeX intends to use the PPP Loan amount for Qualifying Expenses. However, no assurance is provided that AgeX will obtain forgiveness of the PPP Loan in whole or in part.

Staff Reductions

During April 2020, AgeX initiated staff layoffs that affected 12 employees, primarily research and development personnel. AgeX has paid approximately $105,000 in accrued payroll and unused paid time off and other benefits and expects to recognize approximately $194,800 in restructuring charges in connection with the reduction in staffing, consisting of contractual severance and other employee termination benefits, substantially all of which are expected to be settled in cash. The staff reductions followed AgeXs strategic review of its operations, giving consideration to the status of its product development programs, human resources, capital needs and resources, and current conditions in the capital markets resulting from the COVID-19 pandemic.

Going Concern Considerations

As required under Accounting Standards Update 2014-15, Presentation of Financial Statements-Going Concern (ASC 205-40), AgeX evaluates whether conditions and/or events raise substantial doubt about its ability to meet its future financial obligations as they become due within one year after the date its financial statements are issued. Based on AgeXs most recent projected cash flows, and considering that loans from Juvenescence in excess of an initial $500,000 advance under the New Loan Agreement will be subject to Juvenescences discretion, AgeX believes that its cash and cash equivalents, the $500,000 loan under the New Loan Agreement, the PPP Loan and reduction in staff in May 2020 would not be sufficient to satisfy its anticipated operating and other funding requirements for the twelve months following the filing of AgeXs Quarterly Report on Form 10-Q for the three months ended March 31, 2020. These factors raise substantial doubt regarding the ability of AgeX to continue as a going concern.

First Quarter 2020 Operating Results

Revenues: Total Revenues for the first quarter of 2020 were $515,000 as compared with $388,000 for the first quarter of 2019. AgeX revenue is primarily generated from subscription and advertising revenues from the GeneCards online database through its subsidiary LifeMap Sciences, Inc. Revenues in 2020 also included approximately $86,000 of allowable expenses under its research grant from the NIH as compared with $15,000 in the same period in 2019.

Operating expenses: Operating expenses reported for the three months ended March 31, 2020 were $3.7 million as compared to $3.4 million for the same period in 2019. On an as-adjusted basis, operating expenses for the three months ended March 31, 2020 were $3.2 million as compared to $2.8 million for the same period in 2019.

The reconciliation between GAAP and non-GAAP operating expenses is provided in the financial tables included with this earnings release.

Research and development expenses increased by $0.3 million to $1.6 million during the three months ended March 31, 2020 from $1.3 million during the same period in 2019. The increase was primarily attributable to an increase of $0.2 million in scientific consultants, $0.2 million in laboratory facilities and equipment related expenses and maintenance, $0.1 million in personnel related expenses allocable to research and development, and $0.1 million in depreciation and amortization of laboratory equipment and improvements. These increases were offset to some extent by a decrease of $0.3 million in shared services from Lineage Cell Therapeutics, Inc. (Lineage) with the termination of the Shared Facilities and Services Agreement on September 30, 2019.

General and administrative expenses for the three months ended March 31, 2020 remained consistent with the same period in 2019 of $2.1 million despite bearing the full lease and facilities related costs since April 2019, and an increase in head count with the employment of AgeXs own finance team since October 1, 2019. These increases were offset by a decrease in shared facilities and services fees from Lineage following the termination of the Shared Facilities and Services Agreement on September 30, 2019.

About AgeX Therapeutics

AgeX Therapeutics, Inc. (NYSE American: AGE) is focused on developing and commercializing innovative therapeutics for human aging. Its PureStem and UniverCyte manufacturing and immunotolerance technologies are designed to work together to generate highly defined, universal, allogeneic, off-the-shelf pluripotent stem cell-derived young cells of any type for application in a variety of diseases with a high unmet medical need. AgeX has two preclinical cell therapy programs: AGEX-VASC1 (vascular progenitor cells) for tissue ischemia and AGEX-BAT1 (brown fat cells) for Type II diabetes. AgeXs revolutionary longevity platform induced Tissue Regeneration (iTR) aims to unlock cellular immortality and regenerative capacity to reverse age-related changes within tissues. AGEX-iTR1547 is an iTR-based formulation in preclinical development. HyStem is AgeXs delivery technology to stably engraft PureStem cell therapies in the body. AgeXs core product pipeline is intended to extend human healthspan. AgeX is seeking opportunities to establish licensing and collaboration arrangements around its broad IP estate and proprietary technology platforms and therapy product candidates.

For more information, please visit http://www.agexinc.com or connect with the company on Twitter, LinkedIn, Facebook, and YouTube.

Forward-Looking Statements

Certain statements contained in this release are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. Any statements that are not historical fact including, but not limited to statements that contain words such as will, believes, plans, anticipates, expects, estimates should also be considered forward-looking statements. Forward-looking statements involve risks and uncertainties. Actual results may differ materially from the results anticipated in these forward-looking statements and as such should be evaluated together with the many uncertainties that affect the business of AgeX Therapeutics, Inc. and its subsidiaries, particularly those mentioned in the cautionary statements found in more detail in the Risk Factors section of AgeXs most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commissions (copies of which may be obtained at http://www.sec.gov). Subsequent events and developments may cause these forward-looking statements to change. AgeX specifically disclaims any obligation or intention to update or revise these forward-looking statements as a result of changed events or circumstances that occur after the date of this release, except as required by applicable law.

AGEX THERAPEUTICS, INC. AND SUBSIDIARIES

CONDENSED CONSOLIDATED BALANCE SHEETS

(IN THOUSANDS, EXCEPT PAR VALUE AMOUNTS)

March 31,

2020

December 31,

2019

(Unaudited)

ASSETS

CURRENT ASSETS

Cash and cash equivalents

$

468

$

2,352

Accounts and grants receivable, net

366

363

Prepaid expenses and other current assets

1,238

1,339

Total current assets

2,072

4,054

Here is the original post:
AgeX Therapeutics Reports First Quarter 2020 Financial Results and Provides Business Update - Business Wire

Recommendation and review posted by Alexandra Lee Anderson

COVID sheds light on importance of health on the farm – Western Producer

Farmers have always been connected to several aspects of a healthy lifestyle. As food producers, were closely connected to the lifecycle of food, from field to fork.

Were also early pioneers of the concept of community, which happens to be a primary factor for self-reported happiness. But as agriculture has evolved, have we lost aspects of health in our daily lives?

A farm business is only as healthy as its operators and neglecting a healthy lifestyle can result in a vulnerable farming operation and food supply. At the forefront of most health-related topics is physical health.

Farmers often consider themselves to be in good physical condition. Many arent anymore, notes Mike Raine, managing editor of The Western Producer.

There are many reasons for this, but many of them boil down to technology, isolation and automation.

City folks often referred to us as farmer-strong because we grew up lifting bales or twisting and bending to get under or onto equipment. It was heavier work then. The farming lifestyle that the country was built on mostly doesnt exist anymore, and now farmers need to supplement with fitness, says Raine.

Whats less obvious to many is the impact that our psychological health has overall health. And while COVID-19 has only infected a small percentage of the population, the virus that has infected nearly everyone is the virus of fear. Fear is highly contagious, and farmers arent immune.

Whether its the fear of getting sick or the fear of losing a family farming operation due to the economic downturn, this fight or flight response to danger has substantial impacts on immune response. There is strong evidence indicating that healthy individuals respond to COVID-19 more favourably than unhealthy individuals. Much of this can be traced back to the bodys psychological state, which affects the body on a biochemical level.

When we perceive stress, the body produces cortisol. Cortisol is the fight-or-flight response hormone responsible for regulating blood pressure and inflammation. During this process, the body also produces a less desirable hormone called norepinephrine, what is more commonly known as adrenaline. This hormone causes increased heart rate and blood pressure. In situations of chronic stress, the body is unable to produce cortisol and the result is unopposed norepinephrine. The link between mental and physical response to stress, whats referred to as mind-body connection, is more relevant than ever before.

Whats also less mentioned is how closely related anxiety is to asthmatic symptoms and other respiratory conditions. While mild stress can most often be managed, situations of chronic stress often results in physical ailments later on in life. Our mental state, has significant impacts on how the body responds to physical stress.

A prime example of this is the impact that the human mind can have on the outcome of major surgeries. Research has found that viewing a surgeon in a favourable light can have a positive impact on the outcome of surgery.

Certainly, fear isnt always a bad thing; doctors can also use this technique to motivate patients to make positive lifestyle changes to improve overall health.

The dominant factor responsible for increased longevity and happiness is not diet or exercise, its the feeling of being a part of a community. While farmers have always been community-based, they are also incredibly isolated in some circumstances. The possible result of this is loneliness.

Current research suggests the perception of loneliness is the greatest indicator of premature mortality, and isolation can increase this by up to 45 percent. As humans, we are hardwired to be with other humans and these social connections are one of the greatest indicators of health and happiness.

As humans, we are constantly exposed to threats in various forms. Yet somehow it seems as though we believe our health is something that will be gifted to us.

How often does an individual visit their doctor while they are actively working to stay healthy, as opposed to when a significant health-related crisis is occurring?

Arguably, COVID-19 has prompted more people to consider their own health and explore ways to improve their lifestyle. And for good reason, especially considering that many farmers take great satisfaction in having the ability to farm into their 90s.

Staying healthy is critical to our worlds food supplies and the sustainability of the family farm. Health is not merely the absence of illness, but a long-term strategy to building a more sustainable future. Healthy individuals manage profitable family farms and, as an industry, we need to support this.

Katelyn Duncan, PAg, BSA, is a Saskatchewan farmer and agrologist.

Read the original:
COVID sheds light on importance of health on the farm - Western Producer

Recommendation and review posted by Alexandra Lee Anderson

Twenty years of power and energy engagement goes on | ESI-Africa.com – ESI Africa

From its simple beginnings as a metering conference African Utility Week, along with its trusted official host publication ESI Africa, has spent the past two decades closely mirroring the growth of the continents energy, power and water value chains.

This article first appeared inESI AfricaIssue 2-2020.Read thefulldigimaghereorsubscribe to receive a print copy here.

As the continents water and power systems grew and became more sophisticated, the conference and exhibition expanded into one of the largest events on the continent, morphing into African Utility Week and POWERGEN Africa (AUW & PGAF).

David Ashdown, Managing Director Africa for Clarion Events, in conversation with ESI Africa chalks up AUW & PGAFs longevity to its ability to mirror the development and evolution of the market. With the expo weve done well to deliver a premium audience of professionals, representing more than 90 countries. The conference brings together a good cross section of speakers from the continent and abroad while being focused on solution-providing and knowledge-sharing, says Ashdown.

He is curious and excited to see what the future holds for AUW & PGAF as it enters its third decade. While it is too early to tell how a sudden burst of digitisation brought to the fore by the COVID-19 pandemic will affect the event industry as a whole, Ashdown thinks it isnt so much that the digital world is encroaching on live events but that the two are finding a way to blend: Clarion Events has been working across the two forms of media for the past ten years and we have seen a steady convergence. The reach we have through our digital media now culminates in live events as a meeting place.

Enforced lockdowns around the world have changed how Clarion Energys entire global workforce operates: Ultimately, we have to support the industry we serve; however, we can now provide support in the development plans of our stakeholders, to work with them to achieve real results in the power and energy sector.

It is going to be challenging, bouncing back from the pandemic crisis. Our products are well positioned and the discussions at AUW & PGAF in November will be about the resilience of the industry sector and the future outlook. How does Africa manage a crisis situation? I think the situation will accelerate the digitalisation of the sector, of the energy space in Africa and the infrastructure, smart city and IoT elements.

In terms of the traditional conference and exhibitions space, Ashdown does not foresee a move away from face-to-face engagement, as we are human; it is the way we interact.

He adds that through the events media arm, we can communicate with an industry for 365 days a year and connect industry professionals to the benefit of their business, its that element that makes us very valuable. We provide a wide range of media content through our journals platforms, which range from a webinar where individuals speak on a curated topic to a panel bringing industry experts together or a debate on a web portals news story where you can take the conversation into a whole new direction.

Webinars have a huge role to play but rather than replace a physical conference, he believes there will eventually be a blended approach a simulcast where a person who cannot travel can still participate in a virtual way to attend a live conference.

Again, Ashdown points out that one simply cannot remove the human need to connect. There are people who will take a more conservative approach in the short term and the fear and anxiety created by COVID-19 might limit peoples comfort zone. It is our responsibility as event organisers to recognise that and to bring in measures in November to create a safe space.

Is the future of event conferencing virtual, though? That is the holy grail of questions, isnt it? What is the model and what would it look like? That debate could go on for many hours and end with different conclusions. But, what you lack in a purely virtual exhibition is the human connection. A virtual handshake is not the same as President Cyril Ramaphosas elbow greeting, says Ashdown. ESI

http://www.african-utility-week.com | http://www.powergenafrica.com

View original post here:
Twenty years of power and energy engagement goes on | ESI-Africa.com - ESI Africa

Recommendation and review posted by Alexandra Lee Anderson

Falcons Mount Rushmore heavy on the now, yet mindful of who started it all – Atlanta Journal Constitution

Just so you know, were not taking this Mount Rushmore project as simply a lark to fill some space until sports comes back. OK, maybe some of us were. But then it was the Falcons turn, and things got a little tense.

There was the series of phone calls to the writer of this story from an obviously troubled sports editor. He kept suggesting the authors preference of center Jeff Van Note over defensive end Claude Humphrey was unwise. Our dear leader had been chewing and chewing on that choice. Obsessively some might say. Captain Queeg-like others might add.

Then there was the report that the newspapers beat man for the Falcons, D. Orlando Ledbetter, was considering a strongly worded memo, perhaps even an angry Zoom web conference, if Humphrey didnt make the Final Falcons Four.

Suddenly, where before there were only blissful hypotheticals, now there was pressure. It was as if the scales of posterity would pop its springs if we didnt get this right. And the writer of story folded like an old road map.

MORE: Where is Steve Bartkowski?

In many ways, the Falcons presented quite the challenge in coming up with a foursome that represents the best of this franchise since its start in 1966. Its not like theres a championship upon which to moor a selection. And, face it, some of this teams more dynamic players from the past had some real cracks in their character.

One notable quarterback, a civic flashpoint since 2001, had to be excluded because of the clearly stated rules in the Imaginary Mount Rushmore Handbook against dogfighting. If only Michael Vick had just gambled on his own team or torched a homeless shelter, then maybe he would have been up for more serious consideration.

Another, the flashiest player ever to wear black, the one who claimed to have seized the Georgia Dome as his very own house, needed to hang around considerably longer than a fad. Deion Sanders was only five years a Falcon, but so consumed all oxygen in the locker room that it seemed longer. He won Super Bowls with San Francisco and Dallas. He won one first-round playoff game in Atlanta (Braves time excluded).

So mottled is the Falcons past that half their representation on the mythical Mount Rushmore here the two leading vote-getters among the readers as a matter of fact are still-active players. Their personnel file is not even complete, and yet they eclipse the weightiest of Falcons careers dating to the beginning. Were taking it on faith that Matt Ryan is not going to take up dogfighting between now and retirement.

Tommy Nobis already looked like he was cut from stone when he arrived as this franchises first-ever draft pick in 66, so hes a natural for the mountainside. Just look at some old picture of him, you could sharpen a knife on that chin.

A linebacker by trade and a human nail-gun at heart, Nobis was the first Falcon to be named to the Pro Bowl, after recording 294 combined tackles as a rookie. Either he was relentless or the same people who count attendance at Mercedes-Benz Stadium now where charting tackles back then.

For 11 seasons, Nobis was the most feared player with a franchise that too often inspired only indifference. He was martyred on the alter of expansion, enjoying just one winning season and no trips to the postseason. After his playing days, he was a point man for the franchise for decades. Wracked with cognitive and physical ailments later in life, he died in 2017.

For reasons never clear, Nobis cant break through in Canton, to the everlasting discredit of the Hall of Fame. But he is affixed as a Falcons franchise favorite. Of the 2,037 reader votes, Nobis was on 60% of the ballots, third among the electorate, but tops with this one-man electoral college.

Safe to say Thomas Dimitroff is off the hook for trading a jumbo pack of draft picks in 2011 to move up 21 spots to select Alabama receiver Julio Jones. At the time, the hand-wringing was intense. But now it seems to really make it fair, the Falcons should still be sending Cleveland some latter-round compensation.

The top vote-getter in this poll, by a wide margin on 80% of the ballots Jones is recognized as the most gifted and dynamic of Falcons offensive types. He should have had the one single most lovely catch in team annals, the one to cinch a Super Bowl, but you know how that ended.

He is 31 years old, on the other side of prime. But Jones was made from a different batch than the rest of us and no predicting exactly how much more hell polish his resume before hes done. And what he has done to date is plenty: Franchise leader in receiving yards (12,125); receptions per game (6.3) and soon to catch Roddy White in career receptions (his 11 behind Whites 808) and receiving touchdowns (six back of Whites 63).

Now to the throwing part of the equation.

The Falcons have had one league MVP in their history. Even with that singular distinction, Ryan (the 2016 winner) seems to attract an unnatural amount of shrapnel from the fans. At least he came in second, at 68%, in this poll.

In the 192 regular-season games the Falcons have played since 2008, Ryan has started 189 of them. His record as a starter is 109-80. He is eighth all-time among quarterbacks in fourth-quarter comeback wins (30, according to Pro Football Reference.com).

Ryan does more incredible things with numbers than a mob accountant. Take the total of the next three on the list of Falcons career passing yardage leaders Steve Bartkowski, Chris Miller and Chris Chandler. Add them together. And that number still falls short of Ryans 51,186 yards.

Hes 34, a still-dependable high-mileage vehicle. Youll miss him when hes gone, whenever that might be.

Some may have held his exit from Atlanta against Humphrey. Fed up with losing four games into the 1978 season, his option year, Humphrey just left the building. And thus leveraged a trade to Philadelphia in 1979 in exchange for what turned out to be a couple of fourth-round draft picks.

Some may have placed a higher value on longevity, lobbying for Van Note, who led the team in most seasons (18) played, while going to the Pro Bowl six times.

But then some just caved to the argument that Humphrey, after all, is the Hall of Famer between the two, a distinction he mostly earned during nine-plus seasons as a Falcon (1968-78). Three years in Philly earned him a Super Bowl appearance that eventually appeased some Hall of Fame voters (although it took Humphrey 33 years after his retirement to get in).

We yielded as well to the fact that Humphrey just edged Van Note in the fan voting, 37% to 34%.

Humphrey was a 6-foot-4 rush end who terrorized quarterbacks in an age before the sack was an official stat. He, like Nobis, was a rookie of the year, making a great first impression on what was a two-win team. A five-time first team All-Pro, Humphrey was an anchor of the 1977 Grits Blitz defense that allowed a then NFL-record average of only 9.2 points per game.

As for the contentious good-bye, all has been forgiven: In 2008, the Falcons added Humphrey to the teams Ring of Honor. But when carving his likeness onto our Mount Rushmore, a suggestion: Leave it the slightest bit little incomplete perhaps taking just a bit off the end of the nose to mark the 10 games he sat out at the end here.

In the AJCs reader poll, 2,037 voters cast a total of 8,590 votes. Here are the results:Julio Jones, 1,629 votes, 80%Matt Ryan, 1,376 votes, 68%Tommy Nobis, 1,214 votes, 60%Deion Sanders, 1,055 votes, 52%Claude Humphrey, 761 votes, 37%Jeff Van Note, 682 votes, 34%Michael Vick, 548 votes, 27%William Andrews, 530 votes, 26%Mike Kenn, 439 votes, 22%Roddy White, 356 votes, 18%

Support real journalism. Support local journalism. Subscribe to The Atlanta Journal-Constitution today. See offers.

Your subscription to the Atlanta Journal-Constitution funds in-depth reporting and investigations that keep you informed. Thank you for supporting real journalism.

Download the new AJC app. More local news, more breaking news and in-depth journalism. AJC.com. Atlanta. News. Now.

Download the new AJC app. More local news, more breaking news and in-depth journalism. AJC.com. Atlanta. News. Now.

Visit link:
Falcons Mount Rushmore heavy on the now, yet mindful of who started it all - Atlanta Journal Constitution

Recommendation and review posted by Alexandra Lee Anderson

Time to heed the warning bell – The Japan Times

These are my thought about the recent coronavirus pandemic.

Human beings have been dominating all other species on Earth. Now, the human is the only dictator, controlling other creatures, harvesting plants, feeding livestock, catching fish, consuming fossil fuels, producing various merchandise, polluting the air, contaminating oceans, extinguishing forests, melting icebergs, warming climates and exploding our population. All these elements have been accumulating. Human longevity has improved, so many people are concentrating in big cities and can transport over borders. Is this a real evolution? Is this the right direction for our future? Since this pandemic spread, it is really ironic that the environment has been gradually getting better. This is because we came to a point where we had to stop or slow down our basic, productive and social activities to prevent the virus from spreading. I suppose these circumstances seem comfortable and convenient for other species. Mother Earth would be blessed with the absence of humans. What I mean here is the present crisis is supposed to be a kind of punishment from God to conceited humans. Humans got too arrogant, did too much. We should recognize what we have damaged, sacrificed. The pursuit of our comfort and material wealth may not be the only way to sustain our society. We should stop now and think about better and more different ways to coexist with other creatures and Mother Earth.

Now is the moment when the warning bell is ringing loudly.

We have to listen to this sound carefully for assessing our past sins and reforming for the future.

However, like repeating history, we will perhaps again overcome this crisis with our shrewd intelligence and gigantic power without reflecting on ourselves. Furthermore, fortunately, or unfortunately, we are getting back to the previous normal and going in the same direction as ever.

I just hope we "don't miss the bell."

Aizumisato, Fukushima Prefecture

The opinions expressed in this letter to the editor are the writers own and do not necessarily reflect the policies of The Japan Times.

See more here:
Time to heed the warning bell - The Japan Times

Recommendation and review posted by Alexandra Lee Anderson

Human touch is essential. How are people coping with skin hunger? – The World

Dont touch your face."Avoid hugging." Stand 6feet apart."

So many rules about preventing the spread of the coronavirus warn against touching other people. For the last two months, grandparents have been advised against holding their grandchildren while sick patients cannot grasp a relatives hand.

What kind of effect does this lack of human touch haveon people?

Related:COVID-19 interrupts fertility plans for hopeful couples in the United Kingdom

Amanda Whitlock, 39, a photo editor in Chicago, describes herself as a natural introvert. She lives on her own, with her cat Mr. B, and a newly adopted kitten and says shes usually very content in her own company. Whitlock went into a self-imposed lockdown in early March and hasnt had any physical contact with another person since. She says its all starting to get to her.

"I'm someone that has anxiety anyway. The last few days, I think it's really been pretty heavy on me. You know, it would be nice to be able to go out and hang out with someone and hold their hand. You know, something as simple as that, she said.

Theres a good reason why Whitlocks anxiety is on the rise. Studies show physical contact with other people reduces feelings of stress. British evolutionary psychologist and professor Robin Dunbar says it can all be traced back to our monkey ancestry. Grooming each others fur is how apes build friendships. Humans have substituted that grooming with stroking and cuddling, he says and that act of physical touch has a profound effect on our health.

Related:Mourning in the midst of a pandemic

Not only does [touch]build friendships directly and indirectly, but those friendships have a dramatic effect on your well-being, your general health, your ability to recover from illnesses and even your longevity.

"Not only does it build friendships directly and indirectly, but those friendships have a dramatic effect on your well-being, your general health, your ability to recover from illnesses and even your longevity.

Its too early to tell whether the absence of human touch during the pandemic will have long-term consequences. Some groups are particularly vulnerable, like older people living alone, Dunbar says. Playwright Eve Ensler, who now goes by the name V, is worried about how the virus is changing the way we view our bodies. She fears that people are linking human touch with illness.

I think there's something about going out and seeing people being afraid of each other and afraid of each other's bodies.Touch is becoming something equated with sickness and death, and that scares me deeply."

I think there's something about going out and seeing people being afraid of each other and afraid of each other's bodies.Touch is becoming something equated with sickness and death, and that scares me deeply, she said.

The pandemic reminds V of the 1980s when the AIDS virus first became known. Fear of contracting HIV changed attitudes toward sex, and she worries the coronavirus will alter our behavior, too.

[AIDS] definitely changed our relationship to sex and to freedom.Drastically. I so don't want COVID-19 to do this to our relationship to touch. That would be a huge loss for human beings, she said.

Sexual intimacy is off the tablefor many people right now. But for some in the sex industry, its business as usual. Charlotte Rose, an advocate for sex workers in Britain,says many in the industry are still working because theyre not entitled to government support.

There is a large percentage that are still working because they can't claim benefits.A lot of sex workers especially migrant sex workers arent eligible either. So, unfortunately, people are still offering skin-on-skin contact.

Rose used to work in the industry and many of her clients had disabilities. She says for them, it was often not just about sex, but about simple physical contact with another person.

For probably about 90% of my clients,it wasn't even about the intercourse side of it, it was just skin-on-skin contact.I mean, I was predominantly seeing people with disabilities. And, you know, they're already a very marginalized and vulnerable group, and they're the ones that are suffering incredibly at this particular time, she said.

Rose has maintained contact with some of those clients and says a number of them are really struggling with social isolation right now.

Related:Many people arent putting love on hold during COVID-19

Sports and remedial massage therapist Ruth McKinnon knows the importance of human touch in her work, too. Originally from Toronto, McKinnon moved to London in 2017 and began working as a registered massage therapist in the citys financial district.

While many of her clients had physical injuries, McKinnon says theres no question that stress is what brought a lot of people to her clinic. A massage fires up the dopamine in the brain, helping you to relax and ultimately sleep better, she says. But McKinnon hasnt been able to work since mid-Marchwhen the British government announced that all clinics must close because of the pandemic.

McKinnon says shes feeling the effect of the lack of physical contact, too.

Even for myself, not having that regular touch with lots of different people is hard. My husband has noticed an increased amount of touching that I'm doing with him. It's so vital, she said.

McKinnon has no idea when her clinic will open again, but is hopeful she will be able to get back to work soon even if it means wearing protective clothing.

In the meantime, its not all gloom. There are some things you can do to ease the skin hunger you may be feeling. Professor Dunbar says connecting with someone over Skype or Zoom doesnt compare to a good hug but it helps. He jokes that its probably why we have these enormous great white eyeballs."

Theres something about being able to stare into the whites of other people's eyes that seems to be really important in creating that sense of intimacy. On Skype, you stare into the eyeballs and you can see the smile breaking on their face before you even finish the punchline of the joke you're telling them, he said.

In Chicago, Whitlock has been FaceTiming a man she met through a mutual friend. They havent been on a real-life date yet. This week, theyre planning to act out Shakespeares "The Tempest" together on FaceTime. But Whitlock says she longs for the day they can meet in person.

I would love to be able to text him and be like, Hey, let's meet up. Or, you know, since we can't really go anywhere, lets find a safe way in one of our places to meet. That would be awesome, she said.

But Whitlock says she doesnt think its going to happen anytime soon. For now, its just Mr. B and SP, her two cats that are keeping her company.

I think that if I didn't have my pets they're my family. If I didn't have them, I would definitely be climbing the walls right now for some human contact.

See the rest here:
Human touch is essential. How are people coping with skin hunger? - The World

Recommendation and review posted by Alexandra Lee Anderson

COVID-19: How the world is coping with restrictive measures – Medical News Today

Restrictive measures aimed at curbing the new coronavirus pandemic have changed the lives of people all over the world in drastic ways. For this Special Feature, we have asked readers and contributors to share their best coping strategies.

People from all over the world have been reporting that current restrictive measures taken in response to the COVID-19 pandemic have significantly altered the daily course of their lives.

In April, dozens of respondents told Medical News Today about the impact the current public health emergency has had on the well-being of themselves and their loved ones.

But what are people doing to cope? A survey from March, 2020 indicates that in the United States, at least, many individuals have turned to unhealthful coping strategies, such as increased alcohol consumption or the use of other recreational substances.

The same survey also suggests that a majority of U.S. respondents were actively seeking to improve their situation by taking affirmative action.

So what are some helpful coping strategies? To find out, Medical News Today asked readers on social media to tell us what they do make their lives better at this uncertain time.

We also spoke to contributors from all over the world about their top coping tips.

In this Special Feature, we give you an overview of some top coping strategies. We also look at why scientists agree these actions can help improve our well-being.

Many people told MNT that exercising indoors or outdoors, as well as practicing yoga, meditation, or forms of prayer have helped to keep them grounded and focused.

One reader told us that, for them, walking and running [are] [g]reat stress reducers after long days at work, while another mentioned yoga, books, and praying as their go-to in these uncertain times.

Diana, from France, told MNT that it is thanks to regular exercise that she now feels less anxious and more optimistic. I have been exercising every morning with my neighbor, so for the past few days or past week, I have been feeling super positive, and everythings been O.K., she said.

We are permitted 3 hours for any activity, either alone or with one other person, Christina, from Greece, told us. I use this option to go out every day for a run. Therefore, physically and mentally, I feel very good.

It is not surprising that these activities have benefited the mental and physical well-being of people worldwide during the pandemic.

Numerous studies have demonstrated that physical activity, yoga, meditation, and prayer are all linked to better overall health.

Researchers have shown that exercise could prevent depression, boost aspects of our memory, reduce inflammation, and even increase lifespan.

Yoga and meditation could have a direct impact on physiological drivers of stress and resilience to hardship, while the simple presence of religious faith in someones life has ties to longevity.

In countries with less stringent public health emergency measures in place, many people have been taking advantage of the opportunity to take walks in nature.

One reader, reaching out to MNT on social media, said: I go for a walk every day, and I really appreciate nature [and] fresh air.

Researchers have linked walking, as a form of casual, non-strenuous exercise, to a variety of health benefits, including lower blood pressure, improved psychological well-being, and a longer lifespan.

Some of our readers have also said that they try to take advantage of nature and fresh air in any way they can. This might be by stepping outdoors for a while or just sitting out on the balcony.

Since the weather got warmer, [my family and I] have started going out on occasional walks in the forest near our house, Mihai, from Romania, told us.

During the day, [our young son] stays out on the balcony for a while, he tries to [entertain himself by spotting] cats, dogs, pigeons, he added.

One of the main lifelines for me has been reading in the garden in the sunshine, another MNT reader commented on social media.

Many readers have also told us that they have taken up gardening as a means to enjoy the fresh air and sunny weather, if they have access to a garden or a balcony.

While gardening can certainly be calming, it may bring many health benefits besides stress reduction. An older study published in The Medical Journal of Australia associated gardening with a 36% lower risk of developing dementia.

And a study published in the British Journal of Sports Medicine found that gardening also has associations with a lower risk of cardiovascular events such as stroke and heart attack.

But even just taking a moment to admire nature can do wonders for our well-being whether that be in the form of a potted plant, a fresh crop of cilantro grown on the window sill, or observing newly hatched baby ducks at the park.

A research paper published in the Journal of Positive Psychology in 2017 found that simply stopping to notice a bird or a tree has associations with a heightened sense of overall happiness.

Perhaps one of the most challenging aspects of the current pandemic has been of the physical distancing measures adopted by many countries.

Readers from all over the world have told MNT that they are worried about family members and friends whom they cannot see in person. They mention how they miss being able to meet up and engage in fun activities with those they love.

Yet many of them have expressed a strong determination in maintaining that human connection despite all the obstacles.

Almost all of the people reaching out to MNT have said that they have regular phone calls or video calls with friends and family. Some have found ways of replicating the interactions they would typically have with their loved ones over the internet.

Martina, who lives in Belgium, told us that she has been grateful for all the creative get-togethers that the people in her life have been planning:

To cope, I take advantage of the many initiatives organized by friends and family to keep us together. I do yoga online with a friend who is a teacher every day. [] I see my boss and my colleagues every Tuesday for a virtual coffee that [replaces] the ritual of our usual Tuesday lunch together. I have lunch with my family on Zoom almost every Sunday.

Some of the people we spoke to also noted that their employers have been taking steps to maintain their employees team spirit, and an atmosphere of collegiality.

For example, Mihai, in Romania, said that his company has been organizing 2-weekly meetings of 30 minutes each, in which we discuss anything aside from work.

[That is] to reduce our sense of isolation, he explained.

Studies suggest that long, deep conversations help us feel more connected and can enhance peoples sense of well-being. Social interaction may also help protect memory, according to some researchers.

Some experts have also linked lasting friendships and a good social life with better overall health and longevity.

Given all this, it is no wonder that frequent calls with friends, family, and colleagues provide a tangible sense of relief.

Readers who happen to be living with partners, family, or housemates, have also reported that playing board games helps them cope. Others play board games or computer games online with friends.

That, for instance, is the case of Ramona and Simona, who live in Sweden, and Stephen, in Canada, who told us that: Socially, weve been doing video calls and playing online board games and video games with friends and family. We even took part in a Zoom pub quiz.

Researchers have shown that playing and playfulness can help reduce stress levels in adults and increase their overall sense of well-being.

Some people have even linked board games to better brain function, and some studies have suggested that romantic partners who play together stay together, as the excitement and fun of board games help strengthen their bond.

Another favorite coping strategy from respondents all over the world is learning a new skill.

I also spend a lot of time teaching myself web coding through a free online course, taking and editing photos, and brushing up on my French with Duolingo, Stephen also told us, and other readers have sent us similar comments.

Research suggests that learning activities in adulthood may help improve life satisfaction and that learning new languages could help rejuvenate the brain.

All of these activities suggest that growth and adaptability have been key in facing the often life-altering circumstances that the COVID-19 pandemic has brought to everyone.

By scheduling frequent video calls with friends and sticking to a regular exercise routine, people have been doing their best to recreate their usual lifestyle at a different scale while relegated to their home environment.

Some, indeed, have gone to some lengths to do so. Misato, from Japan, told MNT that what she misses most is working from her favorite caf, a place that stimulates her focus and creativity. So she has recreated it at home.

[C]afs used to be one of my favorite places to refresh my thinking and mood but, by analyzing [] why cafs made me comfortable, I made [a] caf section in my room, which eventually reduces my stress, and I currently dont feel any stress not going to cafs.

Misato, Japan

Some researchers think the pandemic may kickstart a boom of creativity, not just in individual contexts but also in diverse economic fields.

While challenging in many ways, the current pandemic may end up proving that humans have what it takes to find a way out of any crisis. Perhaps all that we need, in the end, are some creative strategies.

For live updates on the latest developments regarding the novel coronavirus and COVID-19, click here.

Excerpt from:
COVID-19: How the world is coping with restrictive measures - Medical News Today

Recommendation and review posted by Alexandra Lee Anderson

Global Precision Medicine Software Market Growth and Forecast Research 2020-2027 Cole Reports – Cole of Duty

Globalmarketers.biz recently added a detailed research study focused on the Global Precision Medicine Software Market across the global, regional and country level. The report provides 360 analysis of Market from view of manufacturers, regions, product types and end industries. The research report analyses and provides the historical data along with current performance of the global Precision Medicine Software market and estimates the future trend of industry on the basis of this detailed study.

Request a sample Report :https://www.globalmarketers.biz/report/others/2015-2027-global-precision-medicine-software-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/146709#request_sample

The Major Players are:

Abbott Laboratories(US)Syapse, Inc. (US)Roper Technologies(US)Sunquest Information Systems Inc. (US)Pfizer, Inc., Merck & Co., Inc.(US)N-of-One, Inc. (US)NantHealth, Inc. (US)LifeOmic Health, LLC (US)Fabric Genomics (US)Allscripts(US)GlaxoSmithKline plc(UK)Gene42, Inc. (Canada)Foundation Medicine, Inc. (US)Koninklijke Philips N.V. (Netherlands)PierianDx, Inc. (US)Translational Software, Inc. (US)Flatiron Health, Inc. (US)IBM Watson Group (US)Sanofi S.A.(France)Tempus Labs, Inc. (US)AstraZeneca plc(US)2bPrecise LLC (Israel)Qiagen(Germany)SOPHiA GENETICS SA (Switzerland)Human Longevity, Inc. (US)

The latest research study on the Precision Medicine Software market is a pivotal collection of insights pertaining to this industry vertical, with respect to certain parameters. The research report focuses on providing an in-depth synopsis of this industry, specifically illuminating the market industry size and share, application bifurcation, product types, as well as novel opportunities in the business space.

Segmentation Overview:

Product Type Segmentation :

Cloud-basedOn-premise

Application Segmentation :

Healthcare providersResearch centers & Government institutesPharmaceutical & Biotechnology companiesOther end users

Make an Inquiry About This Report @ https://www.globalmarketers.biz/report/others/2015-2027-global-precision-medicine-software-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/146709#inquiry_before_buying

Driving Forces as well as Challenges of the Precision Medicine Software market: How does the study elaborate on the same?

The report entails the various drivers and restraints impacting the commercialization landscape of the Precision Medicine Software market.

The Precision Medicine Software market research report illustrates details about the myriad challenges which this industry presents. Also, the impact that these challenges may have on the overall industry trends.

Significant details revealed in the report also fall along the likes of market concentration ratio over the forecast years.

Ask for Discount on Precision Medicine Software Market Report at:https://www.globalmarketers.biz/discount_inquiry/discount/146709

The geographical spectrum of the business as well as its influence on the overall Precision Medicine Software market outlook:

With respect to the regional frame of reference, the report segments the Precision Medicine Software market into USA, Europe, Japan, China, India, South East Asia.

Pivotal insights about the product consumption across numerous regions are provided. The revenue recorded by these topographies have been included in the study.

The study explains details about the consumption market share spanning the numerous geographies. It is also inclusive of the market share that these regions accrue over the forecast period, as well as the product consumption growth rate.

For More Details On this Report:

Some of the Major Highlights of TOC covers:

Executive Summary

Global Precision Medicine Software Production Growth Rate Comparison by Types (2015-2027)

Global Precision Medicine Software Consumption Comparison by Applications (2015-2027)

Global Precision Medicine Software Revenue (2015-2027)

Global Precision Medicine Software Production (2015-2027)

North America Precision Medicine Software Status and Prospect (2015-2027)

Europe Precision Medicine Software Status and Prospect (2015-2027)

China Precision Medicine Software Status and Prospect (2015-2027)

Japan Precision Medicine Software Status and Prospect (2015-2027)

Southeast Asia Precision Medicine Software Status and Prospect (2015-2027)

India Precision Medicine Software Status and Prospect (2015-2027)

Check Table of Contents of This Report @ https://www.globalmarketers.biz/report/others/2015-2027-global-precision-medicine-software-industry-market-research-report,-segment-by-player,-type,-application,-marketing-channel,-and-region/146709#table_of_contents

Manufacturing Cost Structure Analysis

Read the original post:
Global Precision Medicine Software Market Growth and Forecast Research 2020-2027 Cole Reports - Cole of Duty

Recommendation and review posted by Alexandra Lee Anderson

Write Again … Mysteries of life – Washington Daily News – thewashingtondailynews.com

For those of us so fortunate, so blessed, to have been on this journey for quite a spell, wondering why weve been allowed this longevity, and so many others havent, is only natural.

Is this by design of some higher power? Or is it caprice? Now, we could discuss and debate this from scientific or religious perspectives, as have just about all who have come before us probably have done. Most would come to an answer based on their own background as Albert Camus wrote: We do not see things as they are. We see things as we are.

About the only way I manage to grapple with such mind-bending mysteries is to acknowledge that the only one who knows such things is our Maker. Well, and maybe one county commissioner, who seems to know just about everything there is to know. It must be a burden to be smarter than everyone else. I wouldnt know, for Ive never had to worry about that.

As the renowned modern-day philosopher, Skybo, says, A mind is a terrible thing. It certainly can be.

But I digress. Getting back to my original question about one of the mysteries of life: By design, or caprice?

Maybe we should really focus on the how long? We can affect the former, but, for most of us, well leave the latter to another power source outside ourselves.

It would perhaps be logical to assume that many, perhaps most, of us have at the very least thought a bit more about our own mortality and about that of family members and friends during this time of the Big V. A palpable angst, for want of a better word, seems to hover about. The news media keep it before us, rightly so, but one can become supersaturated with concern. Just human nature, I suppose.

Minimizing human contact doesnt come easily to most of us. Those who are very social beings.

All of this rambling, mental peregrinations, probably hasnt offered one thing you havent thought about, or pondered.

So. What, if anything, might I offer, suggest, in closing, that might be of any value?

Not being erudite, nor having anything even close to exceptional intellect, all I might add, however unoriginal, is to simply love, or continue to love. People. Animals. Nature. If you are conventionally religious, your maker.

In that vein, please let me leave you with an excerpt from a fairly recent obituary in our paper.

Pure love has no conditions. It does not restrain itself or hold back. Love is a continuous flow without limits and has a sole intention of bringing people together in a time called forever.

A time called forever.

What a beautiful, hopeful, didactic perspective.

To that we might truly say, Amen.

Peace.

Continue reading here:
Write Again ... Mysteries of life - Washington Daily News - thewashingtondailynews.com

Recommendation and review posted by Alexandra Lee Anderson

Brown Bear Car Wash drive-thru forced to remain closed – MyNorthwest.com

(Photo by Justin Sullivan/Getty Images)

Brown Bear Car Wash is currently shut down due to the stay-at-home order in place across Washington state. You can grab a coffee, stop by a pot store to pick up weed, and get a burger on your way home, but you cant wash your car in a drive-thru.

Weve contacted Inslees office directly, been in contact with his special assistant, and the response has been dismissive, said Lance Odermat, vice president of Brown Bear, on the Dori Monson Show. They dont want to hear the reasoning or logic, and we have been told that we are to remain closed under no uncertain terms.

Listeners have texted Dori to say that the car wash at the convenience store or gas station near their house is still open. But these open car washes, Odermat said, are in defiance of the governors rules.

Some of them may be able to plead ignorance, but I know for a fact some of our competitors are acutely aware of the directive we received, and theyre choosing to disregard it, he said.

With our longevity in the community, our reputation, Im not gonna burn that, he added. And even though I disagree with the directive, were gonna adhere to the rule of law as its put out by Governor Inslees office.

Odermat did hear that Costcos car wash is now in compliance, though it previously had been open.

Were all waiting anxiously for further direction from Governor Inslee, Odermat said.

At Brown Bear Car Wash, it is possible to get your car washed with no human interaction.

Across our network, weve got these automated pay stations. You dont even have to roll down your window if youre one of our unlimited club members, and thats about half our customer base, Odermat said. Theres no human interaction required, but yet theyve deemed us non-essential.

Odermat also said the Washington State Patrol is one of their largest fleet accounts. Pointing that out to the state did not help, and they were still told they can not open.

Meanwhile, as pollen counts are high and spring weather is in full swing, people are turning to washing cars in their driveway, pushing soap into the storm drains. According to its website, Brown Bear Car Wash promotes eco-friendly practices, uses less water, and ensures that the pollutants on cars do not go into waterways and storm drain systems.

Its not just the environment, its the economy, Odermat said. Were losing huge sums of money and, Ill point out, were keeping everybody on the payroll, and we dont have a single minimum wage job. Every position in our company starts above minimum wage, and were continuing to eat those costs and take care of our people.

Dori: Is Inslee crashing regional economy to get state income tax?

Brown Bear Car Wash was started by Odermats father in 1957.

I think a lot of us in the business community are hanging on and hoping like crazy that theres going to be some relief here today or tomorrow announced in these news conferences, he said. But if the order continues on unchanged, I really fear for the consequences of the local economy.

Read the original:
Brown Bear Car Wash drive-thru forced to remain closed - MyNorthwest.com

Recommendation and review posted by Alexandra Lee Anderson


Page 3«..2345..1020..»