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Category : Nanomedicine

SpaceX Takes Remotely Controlled Drug Delivery System to the ISS – Interesting Engineering

The International Space Station (ISS) is a unique laboratory available to mankind. The micro-environment, the extreme conditions, and the demanding requirements of space make it an excellent test field for new ideas and devices. Reaching the ISS laboratory this Monday is a next-generation implantable drug delivery system that can be operated remotely and could be used to treat and even prevent chronic ailments back on Earth.

The system is one of the many science experiments that were launched on theCommercial Resupply Services 23 (CRS-23), undertaken by SpaceX and NASA. The third mission for SpaceX, under an agreement, where privately operated spacecraft transport cargo and supplies to the ISS, used the Cargo Dragon 2 capsule, and reused a Falcon 9 booster, NASA said in a press release.

Considered insignificant and irrelevant to human existence just a couple of decades ago, experiments on the ISS are now looked at as a gateway to the science of the future. As colonization of planets comes closer to reality, it is pertinent to know the impact of space travel on humans and also if materials known on Earth retain their properties in different environments. More than 3,000 experiments have been carried out onboard the ISS so far, Nature reportedlast year.

Joining the list is the remotely controlled implantable drug delivery system, developed by Professor of Nanomedicine,Alessandro Grattoni, and his team at the Houston Methodist Research Institute. The purpose of the implantable drug delivery systems is to deliver precise quantities of medication only to target delivery sites in the body. While previous iterations have used specialized membranes to do this passively, Grattoni and his team have now developed an active system that can be controlled remotely using an app.

Faraday Research Facility (FRF), a multi-purpose research facility that is designed to connect with the ISS, houses the system. Inside the FRF are smaller chambers that can hold different experiments in place to be conducted in space. Developed byProXopS, LLC, the FRF can hold up to 12 research environments in place and can be operated from the ground using the ISS Wi-Fi.

Grattoni's trial system consists of sealed containers of saline tubes that will be operated from the ground. If successful, a future flight will use this system to deliver drug doses in rodent subjects, enabling complex drug dose regimens without stressing the subjects, the press release said. Apart from using the system for telemedicine back on Earth, it might also be utilized in astronauts who are on long-duration space missions and for diseases such ashypertension, rheumatoid arthritis, and sleep disorders.

Also on board the FRF is an experiment from the Girl Scouts who have sent ants to see how they colonize in low-gravity environments.

Onboard the cargo that will dock on Monday is a robotic arm from GITAI Japan to the feasibility of using robots to do routine and hazardous tasks in orbit. The technology could also be applied for disaster relief and servicing of nuclear power plants, back on Earth, said a NASA press release.

Astronauts on the ISS will also use a device that will attach to their iPad and take images of their retina. This is expected to improve our understanding ofSpace-Associated Neuro-Ocular Syndrome (SANS), seen in two-third of the astronauts, who have spent a month or longer in space.

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SpaceX Takes Remotely Controlled Drug Delivery System to the ISS - Interesting Engineering

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Updating the PLOS ONE Nanomaterials Collection Author Perspectives, Part 3 – EveryONE – PLoS Blogs

In July, we updated our Nanomaterials Collection, featuring papers published over the past few years in PLOS ONE. This collection showcases the breadth of the nanomaterials community at PLOS ONE, and includes papers on a variety of topics, such as the fabrication of nanomaterials, nanomaterial-cell interactions, the role of nanomaterials in drug delivery, and nanomaterials in the environment.

To celebrate this updated collection, we are conducting a series of Q&As with authors whose work is included in the collection. Next out is our conversations with Roberto Vazquez-Muoz from the University of Connecticut Health Center, Roselyne Ferrari from Universit de Paris and Yerol Narayana from Mangalore University. They discuss the future potential of nanomaterials research, the value of open science practices, and their experiences of pursuing unexpected effects seen in the lab. We will be adding more author interviews over the next few weeks, so please do keep checking back.

Roberto Vazquez-Muoz University of Connecticut Health Center

Currently, I work at the University of Connecticut Health Center (UConn Health), USA. Im a nanomedicine scientist with a multidisciplinary background: B.Sc. with a concentration in Biology, with postgraduate education in Microbiology (M. Sc.) and Nanotechnology (Ph.D.). My research focuses on the complex systems interactions between antimicrobial nanomaterials (nanoantibiotics), microbial cells (pathogens and probiotics), antibiotics, and the environment. My goal is to develop affordable, novel nanotechnology-based solutions to combat multidrug-resistant infectious diseases, particularly for communities under limited resources. My network includes international and transdisciplinary research teams to develop applied nanotechnology solutions for the agricultural, veterinary, and clinical sectors. My work has been published in international peer-reviewed journals, and I have developed patented and commercial products. Ive been awarded by different institutions such as The Ensenada Center for Scientific Research and Higher Education (Mexico), Rotary Internationals Rotaract, the International Network of Bionanotechnology, and the New England I-Corps (MIT)/Accelerate (UCONN) program.

Roberto Vazquez-Muozs paper in the Nanomaterials Collection: Vazquez-Muoz R, Meza-Villezcas A, Fournier PGJ, Soria-Castro E, Juarez-Moreno K, Gallego-Hernndez AL, et al. (2019) Enhancement of antibiotics antimicrobial activity due to the silver nanoparticles impact on the cell membrane. PLoS ONE 14(11): e0224904. https://doi.org/10.1371/journal.pone.0224904

What motivated you to work in this field?

RVM: My motivation to work in this field comes from my interest in the impact of infectious diseases through history and our ability to create solutions to combat them. This interest led me to focus on the interactions between nanomaterials, microbial cells, and antimicrobial substances for combat infection. Additionally, as current treatments are less and less effective against pathogens, nanotechnology has proven to be an effective strategy to fight the crisis of infectious diseases.

Nanomaterials research has increased in popularity over the past few years as a research topic. Do you envision that the field can continue to grow this way, and do you see any challenges on the horizon?

RVM: Yes, nanomaterials research has increased in popularity worldwide, and we have seen exponential growth in publications. The field will continue to grow for years as we constantly discover nanomaterials novel structures, properties, and applications. Additionally, we continuously develop novel synthesis methods and understand the interactions between nanomaterials and other systems (organisms, materials, environment, etc.).

However, there are several challenges on the horizon. A critical challenge is understanding the impact of nanomaterials on living organisms and the environment. It is crucial to expand the research on human and ecological nanotoxicology and the fate of nano-waste on the environment. Another challenge is the standardization of research data. As nanomaterials research is a multidisciplinary field, there is still a lack of standard criteria for conducting and publishing research, leading to difficulties in comparing data from different studies.

Can you tell us about an experience during your research, whether in the lab or at the computer or in conversation etc., where something finally clicked or worked?

RVM: One of my experiences during my research is when I was working on how nanomaterials increase the antibacterial activity of antibiotics. Different published studies showed the impact of nanomaterials on cell structure and metabolism. At the same time, other studies reported synergistic or antagonistic activity between nanomaterials and antibiotics; however, their explanations about the mechanisms were primarily theoretical. Unfortunately, there was no apparent connection between the proposed mechanisms and the synergistic activity reported by other groups. To fill that knowledge gap, we conducted experimental work to evaluate the physical and chemical interactions in the nanomaterials-antibiotics-microbial cell complex system. Then, when we compared our data with the literature, we started to see the connecting dots that could explain the synergistic activity of antibiotics. Moreover, our model could also explain some results published from other groups. That project was a stimulating and satisfactory experience and contributed to a better understanding of the synergistic activity of nanoparticles with antibiotics.

Is there a specific research area where a collaboration with the nanomaterials community could be particularly interesting for interdisciplinary research?

RVM: There are many research areas where interdisciplinary and transdisciplinary collaboration with the nanomaterials community is exciting. Nanomedicine is my first pick. The novel properties of nanomaterials have raised a lot of interest from the medical community, particularly for drug delivery, controlled release, reducing toxicity, among others. Additionally, beyond treatments, the development of new instrumentation, biosensors, analytical kits, sanitizing formulations, and other related applications for the healthcare sector is on the rise, creating more opportunities to work in diverse, interdisciplinary environments. In this regard, I have an interdisciplinary background (microbiology and nanotechnology), and my work focuses on medical applications, which allows me to participate in different research groups.

Roselyne Ferrari Universit de Paris

I am an Associate Professor in the Paris Diderot University (now Universit de Paris) since 1994. I defended my PhD thesis entitled Investigation of foliar lipid peroxidation in higher plants and evaluation of antioxidant capacities of sensitive or drought-resistant plants in 1992 (Paris Diderot University, France) in the field of Tropical Plant Biology. I then got interested in microorganisms and studied a class of enzymes capable of detoxifying fatty acid hydroperoxides: the alkylhydroperoxide reductases. I then investigated the ability of Escherichia coli to detoxify emerging pollutants in aquatic environments and in particular man-made metal oxide nanoparticles. I participated for 10 years in the development of laboratory tests to assess the toxicity of zinc oxide and titanium nanoparticles in natural aquatic environments. I showed, through metabolomics and proteomics, that E. coli tries to overcome the stress caused by nanoparticles by increasing its oxidative and respiratory capacity. More recently, I started to work again on polyunsaturated fatty acids and peroxidation phenomena, but this time on fungi. Recently I am also interested in the ability of some microscopic coprophilous fungi to destroy lignocellulose. These ascomycete fungi are over-equipped with hydrolytic enzymes, such as oxidases or oxygenases.

Roselyne Ferraris paper in the Nanomaterials Collection: Planchon M, Lger T, Spalla O, Huber G, Ferrari R (2017) Metabolomic and proteomic investigations of impacts of titanium dioxide nanoparticles on Escherichia coli. PLoS ONE 12(6): e0178437. https://doi.org/10.1371/journal.pone.0178437

What is your favorite thing about nanomaterials?

RF: I am interested in the toxicology of nanoparticles in the environment and more particularly in their dissemination in the 3 compartments (soil water air). I am also interested in the fixation of environmental metal oxide nanoparticles by the bark of urban trees.

Have you had any surprises in your research recently, where the result was not what you expected?

RF: I did indeed have some surprises in the results I got in the paper I published in PLOS ONE. I did not expect that the amount of ATP would increase in Escherichia coli bacteria after they were brought into contact with the titanium dioxide nanoparticles. Unfortunately I did not pursue this line of research and I remain on this question.

Did you have to adapt your work in light of the pandemic, and if so, how?

RF: I adapted like many researchers and continued my work following the recommendations of my University.

What do you see as the greatest opportunities for disseminating research in your field, or for communicating science in general?

RF: Social networks, media in general have allowed us to continue to disseminate to our fellow researchers as well as video conferencing.

Yerol Narayana Mangalore University

Obtained MSc and PhD from Mangalore University. Presently the Professor and Chairman, Board of Studies, Department of Physics of Mangalore University. Area of research include Environmental Radioactivity, Radiation Biophysics and Nanoparticles for Biomedical Applications. Published more than 150 research papers in International Journals and presented more than 250 research papers in conferences. Completed five major research projects and one major research project is ongoing. Guided 13 students for PhD degree and 8 students are currently working for their PhD degree. Received Commonwealth Fellowship Award for Post-Doctoral research in the United Kingdom during 2000-2001, Wington Tiular Fellowship award from ACU in 2013, Dr A K Ganguly Award from Indian Association for Radiation Protection, India in 2016, Best Teacher Award from Mangalore University in the year 2017 and Best Research Publication Award from Govt. of Karnataka, India, in 2019.

Yerol Narayanas paper in the Nanomaterials Collection: Suvarna S, Das U, KC S, Mishra S, Sudarshan M, Saha KD, et al. (2017) Synthesis of a novel glucose capped gold nanoparticle as a better theranostic candidate. PLoS ONE 12(6): e0178202. https://doi.org/10.1371/journal.pone.0178202

What route did you take to where you currently are in your career?

YN: I obtained my Masters degree in physics from, Mangalore University in 1989 and PhD degree from the same University in 1994. I joined the Physics Department of Mangalore University in 1995 as Assistant Professor and subsequently became Professor in 2010. I have done my Post-doctoral research at BGS, UK during 2000-01 under the commonwealth fellowship and subsequently at University of Stirling, UK in 2014 under Wighton-Titular Fellowship. Currently I am working as Professor of Physics at Mangalore University.

How important are open science practices in your field? Do you have any success stories from your own research of sharing or reusing code, data, protocols, open hardware, interacting with preprints, or something else?

YN: Open science practices are very useful in any field of scientific research. In my field, open access to published scientific materials have helped in a big way in designing experiments, data analysis and furtherance of research.

If you could dream really big, is there a particular material, function or material property that seems far away at the moment, but you think could be attained in the future?

YN: At present the major challenge in Radiotherapy is the radio-resistance of tumor cells and protecting the normal cells. Researchers are working on a concept of multiple therapy i.e. simultaneous chemotherapy, immunotherapy, hyperthermia therapy and radiotherapy to overcome the radio-resistance and it has been proved to be effective. Live tumor imaging is another big challenge. Some nanoparticles have shown potential to improve the aforesaid individual treatment and imaging techniques. At present, individual nanomaterials are being tried for treatment and imaging. The usage of multiple nanomaterials simultaneously would not be safe as their unique interaction mechanism may create unforeseen problems. Therefore, we need a single nanomaterial that is capable of supporting multiple therapy and live imaging to reduce the side effects and to assure safety. We believe that it will be a reality in the near future.

Disclaimer: Views expressed by contributors are solely those of individual contributors, and not necessarily those of PLOS.

Featured image: http://dx.doi.org/10.1371/journal.pone.0133088

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Updating the PLOS ONE Nanomaterials Collection Author Perspectives, Part 3 - EveryONE - PLoS Blogs

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Get Huge Discount on Nanomedicine Market by Forecast to 2026 with Profiling Top Players GE Healthcare, Johnson & Johnson, Mallinckrodt plc, Merck…

Global Nanomedicine Market Report is recently published by Reports N Markets is a value addition to the studied Market. The compilation of the research report is conditioned by primary and secondary research techniques. The report also elaborates on factors that are fueling or hampering the growth of the current Global Nanomedicine Market. It focuses on recent trends and technologies that boost company performance. It also offers a panoramic view of the competitive landscape that will aid in differentiating competition at global and national level. To approximate risks and challenges involved, various business models have been presented.

Download Sample Copy of this Report: https://www.reportsnmarkets.com/request_sample.php?id=97555&mode=hbs

It enumerates the financial aspects of the businesses such as profit margin, gross margin, market shares, and pricing structures. Business profiles of several top-level industries have been examined to get a clear idea about the successful strategies followed by them. The report is rich with illustrations like infographics, charts, tables, and pictures to generate a strong footing for detailed analysis of recent trends and technological advancements in the Global Nanomedicine Market.

Market Segment as follows:

Product Type Segmentation Includes

Regenerative Medicine

In-vitro & In-vivo Diagnostics

Vaccines

Drug Delivery

Application Segmentation Includes

Clinical Cardiology

Urology

Genetics

Orthopedics

Ophthalmology

Companies Includes

GE Healthcare

Johnson & Johnson

Mallinckrodt plc

Merck & Co. Inc.

Nanosphere Inc.

Pfizer Inc.

Sigma-Tau Pharmaceuticals Inc.

Smith & Nephew PLC

Stryker Corp

Teva Pharmaceutical Industries Ltd.

UCB (Union chimique belge) S.A

Get Best Discount on this Report: https://www.reportsnmarkets.com/ask_for_discount.php?id=97555&mode=hbs

Table of Contents

Chapter 1 Global Nanomedicine Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Nanomedicine Market Competition by Companies

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Nanomedicine Market Analysis by Application

Chapter 8 Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Global Nanomedicine Market Effect Factors Analysis

Chapter 12 Global Nanomedicine Market Forecast

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Surging nanomedicine virtuous circle develops between investment and healthtech – Korea IT Times

COVID-19s outbreak has coincided with investments flooding into nanomedicine healthcare companies, according to the latest data. The investment monitoring platform reported that the sector benefited by 1.7bn in 2020 - 1.1bn more than the year before.

Nano Magazine has highlighted a report by Market DataForecastthat the global nanomedicine market, worth $141.34 billion in 2020, will rise to $258.11bn by 2025. The report also highlights a huge upsurge of investment support from governments and funds to develop nano therapies for vaccines, diagnostic imaging, regenerative medicine, and drug delivery following the impact of COVID-19.

Furthermore, nanomedicine offers huge advantages for wider healthcare, also affected by the pandemic and Long-COVID after-effects upon cardiovascular, respiratory, neurological, immunological-related diseases.

This aligns with investment monitoring platform Pitchbooks forecast that health tech investment overall will top $10 trillion by 2022 and that nanomedicine investment has grown the sector by 250% in the last five years.

Median nanotech healthcare deal sizes have also doubled since 2019, from 1 million to 2m in 2021, while the number of deals in 2020 was greater than ever, overtaking 100 deals in a single year for the first time.

Nanomedicine is transforming healthcare innovation and delivering early intervention and targeted drug delivery and testingNanomedicine is transforming healthcare innovation and delivering early intervention and targeted drug delivery and testing

Investment is already aiding innovation as nanotech researchers and scientists work to improve biomedical devices such as prosthetics, provide new cancer treatments, and develop bone healing therapies, along with more innovations that could transform global healthcare.

Nanotech researchers have found nanobodies that block the COVID-19 and, potentially, other coronaviruses from entering cells and developed mask designs at nanoscale making them both cheaper and more effective.

The fast global response to the pandemic was also enabled by nanotechnology, being pivotal in Pfizer and AstraZeneca vaccine development and Innova Medical Groups 30-minute lateral flow COVID tests.

World Nano Foundation co-founder Paul Stannard said COVID-19 highlighted weaknesses in healthcare systems across the developed world, proving that long-term, innovative solutions are needed to enable change and prevent future pandemics, with nanomedicine playing an ever-greater role in this transformation of global healthcare.

And while impressed by rising investments in and recognition for the nanotech sector, he warned against any let-up in this trend:

Nanotechnology is not only crucial to our current healthcare systems, but researchers and scientists in this field are on the cusp of therapies, devices, and innovation that will revolutionize how we move forward.

To ensure pandemic preparedness, high-quality healthcare, and longevity, we must invest in nano healthtech and care innovations.

His message was echoed by Kojo Annan (son of late and former UN secretary-general Kofi Annan) who is a general partner in the Luxembourg-based Vector Innovation Fund, which recently launched a sub-fund raising an initial $300m for pandemic protection and preparedness.

Annan said: A virtuous circle is developing between investment and healthtech. Lately, we have seen the development of multiple vaccines, acceleration of technologies linked to decoding the genome, the rise of nanomedicine and the use of artificial intelligence to monitor infectious diseases and new pathogens.

More investment in sustainable healthtech funding can only accelerate this trend, bringing the fairer and global distribution of healthcare, greater affordability, and preventive and early intervention healthcare, all ultimately improving the longevity of life.

The pandemic has also transformed telemedicine investment and demonstrated that nanoscience and innovation could deliver more resilient societies and ecosystems for healthcare.

Korea IT Times

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Surging nanomedicine virtuous circle develops between investment and healthtech - Korea IT Times

Recommendation and review posted by Alexandra Lee Anderson

Covid-19 Impact Analysis on Nanomedicine Market by Forecast to 2026 with Profiling Top Players GE Healthcare, Johnson & Johnson, Mallinckrodt…

Global Nanomedicine Market Report is recently published by Reports N Markets is a value addition to the studied Market. The compilation of the research report is conditioned by primary and secondary research techniques. The report also elaborates on factors that are fueling or hampering the growth of the current Global Nanomedicine Market. It focuses on recent trends and technologies that boost company performance. It also offers a panoramic view of the competitive landscape that will aid in differentiating competition at global and national level. To approximate risks and challenges involved, various business models have been presented.

Download Sample Copy of this Report: https://www.reportsnmarkets.com/request_sample.php?id=97555&utm_source=Blog&utm_medium=HS

It enumerates the financial aspects of the businesses such as profit margin, gross margin, market shares, and pricing structures. Business profiles of several top-level industries have been examined to get a clear idea about the successful strategies followed by them. The report is rich with illustrations like infographics, charts, tables, and pictures to generate a strong footing for detailed analysis of recent trends and technological advancements in the Global Nanomedicine Market.

Market Segment as follows:

Product Type Segmentation Includes

Regenerative Medicine

In-vitro & In-vivo Diagnostics

Vaccines

Drug Delivery

Application Segmentation Includes

Clinical Cardiology

Urology

Genetics

Orthopedics

Ophthalmology

Companies Includes

GE Healthcare

Johnson & Johnson

Mallinckrodt plc

Merck & Co. Inc.

Nanosphere Inc.

Pfizer Inc.

Sigma-Tau Pharmaceuticals Inc.

Smith & Nephew PLC

Stryker Corp

Teva Pharmaceutical Industries Ltd.

UCB (Union chimique belge) S.A

Get Best Discount on this Report: https://www.reportsnmarkets.com/ask_for_discount.php?id=97555&utm_source=Blog&utm_medium=HS

Table of Contents

Chapter 1 Global Nanomedicine Market Overview

Chapter 2 Global Economic Impact on Industry

Chapter 3 Global Nanomedicine Market Competition by Companies

Chapter 4 Global Production, Revenue (Value) by Region

Chapter 5 Global Supply (Production), Consumption, Export, Import by Regions

Chapter 6 Global Production, Revenue (Value), Price Trend by Type

Chapter 7 Global Nanomedicine Market Analysis by Application

Chapter 8 Cost Analysis

Chapter 9 Industrial Chain, Sourcing Strategy and Downstream Buyers

Chapter 10 Marketing Strategy Analysis, Distributors/Traders

Chapter 11 Global Nanomedicine Market Effect Factors Analysis

Chapter 12 Global Nanomedicine Market Forecast

For More Information: https://www.reportsnmarkets.com/enquiry_before_buying.php?id=97555&utm_source=Blog&utm_medium=HS

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Covid-19 Impact Analysis on Nanomedicine Market by Forecast to 2026 with Profiling Top Players GE Healthcare, Johnson & Johnson, Mallinckrodt...

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Global Healthcare Nanotechnology (Nanomedicine) Market 2021 Production, Revenue, Price and Gross Margin Analysis with Forecasts Jumbo News – Jumbo…

Healthcare Nanotechnology (Nanomedicine) Market report provides strategic supports mentioned by the business specialists with market sources, amount of manufacturing cost structure, raw materials, forecasts, turnover, manufacturing outlays, latest market trends, labor cost, demands and much more. Healthcare Nanotechnology (Nanomedicine) market reportcovers a comprehensive market structure through the globe with an in-depth study of major dynamics (Drivers, Challenges, Opportunities).

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Key Market Trends:

The Growth of Nanomedicine is Expected to Provide High Opportunities for the Treatment of Neurological Diseases, Over the Forecast Period

A large number of brain disorders with neurological and psychological conditions result in short-term and long-term disabilities. Recent years observed a significant number of research studies being published on methods for the synthesis of nanoparticle-encapsulated drugs within in vivo and in vitro studies. The insufficient absorbance of oral drugs administered for a range of neurological conditions, such as Alzheimers disease, Parkinson disease, tumor, neuro-AIDS, among others, opens up the necessity of nanomedicine with stem cell therapy. Some of the registered nanoparticles for the complex CNS treatment are a gold nanoparticle, lipid nanoparticle, and chitosan nanoparticles.

Other than neurological diseases, research-based progress was found in the treatment of cancers, with the scientific communities identifying new metabolic pathways to find better drug combination using nanomedicine.

North America is Expected to Hold the Largest Share in the Market

In the United States, several companies are closely observing the developments in nanostructured materials across various applications in the healthcare industry, including medical devices, to improve efficiency and efficacy. In the United States, the National Nanotechnology Initiative (NNI), which was initiated in 2000, is among the supreme bodies that manage all nanotechnology-related activities. Under the NNI, several agencies are working in collaboration with companies and universities. For instance, nano-manufacturing in Small Business Innovation Research (SBIR) programs were developed for both commercial and public use. Companies are targeting the treatment of several cancer types and infectious diseases through immunotherapy, where nanoemulsion vaccines and drugs play a significant role. In the United States, one of the major challenges associated with nanotechnology is the ability to integrate nanoscale materials into new devices and systems, along with an application of novel properties at the nano-level. Thus, most of the companies are investing in R&D. Nanotechnology is likely to play a significant role in the delivery of drugs. In the recent strategic plan presented by the NNI in 2016, several programs were identified to further advance the research and development programs, over the forecast period.

Market Overview:

Key Manufacturers Like

Scope of the Report:

Healthcare Nanotechnology (Nanomedicine) market report focuses on the latest trends in the global and regional spaces on all the significant components, including the capacity, cost, price, technology, supplies, production, profit, and competition. Moreover, the old data and present development of the Healthcare Nanotechnology (Nanomedicine) market have been given in the scope of the report. The latest trends, product portfolio, demographics, geographical segmentation, and regulatory framework of the Healthcare Nanotechnology (Nanomedicine) market have also been involved in the study.

Market Dynamics:

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Key Questions Answered in Market Report:

Lastly, the Global Healthcare Nanotechnology (Nanomedicine) Market Research covers a complete market structure across the world with a comprehensive analysis of major key factors. This report provides planned orientations referred by the industry experts.

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Study objectives of Healthcare Nanotechnology (Nanomedicine) Market Report:

Detailed TOC of Healthcare Nanotechnology (Nanomedicine) Market Report 2019-2024:

1 INTRODUCTION1.1 Study Deliverables1.2 Study Assumptions1.3 Scope of the Study

2 RESEARCH METHODOLOGY

3 EXECUTIVE SUMMARY

4 MARKET DYNAMICS4.1 Market Overview4.2 Market Drivers4.2.1 Growing Prevalence of Cancer and Genetic and Cardiovascular Diseases4.2.2 Increasing Advancements in Nanoscale Technologies for Diagnostic Procedures4.2.3 Growing Preference for Personalized Medicines4.3 Market Restraints4.3.1 High Cost4.3.2 Stringent Regulations for Commercial Introduction4.4 Porters Five Forces Analysis4.4.1 Threat of New Entrants4.4.2 Bargaining Power of Buyers/Consumers4.4.3 Bargaining Power of Suppliers4.4.4 Threat of Substitute Products4.4.5 Intensity of Competitive Rivalry

5 MARKET SEGMENTATION5.1 By Application5.1.1 Drug Delivery5.1.2 Biomaterials5.1.3 Active Implants5.1.4 Diagnostic Imaging5.1.5 Tissue Regeneration5.1.6 Other Applications5.2 By Disease5.2.1 Cardiovascular Diseases5.2.2 Oncological Diseases5.2.3 Neurological Diseases5.2.4 Orthopedic Diseases5.2.5 Infectious Diseases5.2.6 Other Diseases5.3 Geography5.3.1 North America5.3.1.1 US5.3.1.2 Canada5.3.1.3 Mexico5.3.2 Europe5.3.2.1 France5.3.2.2 Germany5.3.2.3 UK5.3.2.4 Italy5.3.2.5 Spain5.3.2.6 Rest of Europe5.3.3 Asia-Pacific5.3.3.1 China5.3.3.2 Japan5.3.3.3 India5.3.3.4 Australia5.3.3.5 South Korea5.3.3.6 Rest of Asia-Pacific5.3.4 Middle East & Africa5.3.4.1 GCC5.3.4.2 South Africa5.3.4.3 Rest of Middle East & Africa5.3.5 South America5.3.5.1 Brazil5.3.5.2 Argentina5.3.5.3 Rest of South America

6 COMPETITIVE LANDSCAPE6.1 Company Profiles6.1.1 Sanofi SA6.1.2 Celegene Corporation6.1.3 CytImmune Sciences Inc.6.1.4 Johnson & Johnson6.1.5 Luminex Corporation6.1.6 Merck & Co. Inc.6.1.7 Nanobiotix6.1.8 Pfizer Inc.6.1.9 Starpharma Holdings Limited6.1.10 Taiwan Liposome Company Ltd

7 MARKET OPPORTUNITIES AND FUTURE TRENDS

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Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric Materials in Nanotechnology and Nanomedicine-Specific Cancer Targeting…

This article was originally published here

Chem Rev. 2021 May 26. doi: 10.1021/acs.chemrev.1c00009. Online ahead of print.

ABSTRACT

RNA nanotechnology is the bottom-up self-assembly of nanometer-scale architectures, resembling LEGOs, composed mainly of RNA. The ideal building material should be (1) versatile and controllable in shape and stoichiometry, (2) spontaneously self-assemble, and (3) thermodynamically, chemically, and enzymatically stable with a long shelf life. RNA building blocks exhibit each of the above. RNA is a polynucleic acid, making it a polymer, and its negative-charge prevents nonspecific binding to negatively charged cell membranes. The thermostability makes it suitable for logic gates, resistive memory, sensor set-ups, and NEM devices. RNA can be designed and manipulated with a level of simplicity of DNA while displaying versatile structure and enzyme activity of proteins. RNA can fold into single-stranded loops or bulges to serve as mounting dovetails for intermolecular or domain interactions without external linking dowels. RNA nanoparticles display rubber- and amoeba-like properties and are stretchable and shrinkable through multiple repeats, leading to enhanced tumor targeting and fast renal excretion to reduce toxicities. It was predicted in 2014 that RNA would be the third milestone in pharmaceutical drug development. The recent approval of several RNA drugs and COVID-19 mRNA vaccines by FDA suggests that this milestone is being realized. Here, we review the unique properties of RNA nanotechnology, summarize its recent advancements, describe its distinct attributes inside or outside the body and discuss potential applications in nanotechnology, medicine, and material science.

PMID:34038115 | DOI:10.1021/acs.chemrev.1c00009

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Thermostability, Tunability, and Tenacity of RNA as Rubbery Anionic Polymeric Materials in Nanotechnology and Nanomedicine-Specific Cancer Targeting...

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Nanomedicine Market Overview, Production, Statistics, Geography Trends and Forecasts 2021 to 2026 KSU | The Sentinel Newspaper – KSU | The Sentinel…

Chicago, United States:-A Versatile New Research Report On The GlobalNanomedicine Marketaims to promise a unique approach towards an industry assessment of the Nanomedicine market that covers the most important factors driving the growth of the industry. The Nanomedicines market report makes available the current and future technical and financial details of the industry. It is one of the most comprehensive and important additions toReports N Marketsarchiveof market research studies. It offers detailed research and analysis of key aspects of the global Nanomedicine market. This report explores all the key factors affecting the growth of the global Nanomedicines market including supply and demand scenario, pricing structure, profit margins.

Top Key players cited in the report:Consumer Electronics, Automotive, Lense, Others

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Our impartial and unbiased approach toward Nanomedicine market research is one of the major benefits offered with this research study. While internal analysis holds great importance in market research, secondary research helps guide changes during the preparation of a Nanomedicine research report. We dont simply take the word of third parties, we always look for justification and validation before using their data or information in our research study. We have attempted to give a holistic view of the global Nanomedicine market and benchmark almost all important players of the industry, not just the prominent ones. As we focus on the realities of the global Nanomedicine market, be rest assured that you are on the right path to receiving the right information and accurate data.

Proceeding further, the study scrutinizes COVID-19 footprint on the industry, highlighting the impediments faced by companies, such as disruptions in supply-demand and complications in cost-management. In this context, the research document helps in building actions plans that ensure profitability and continuity of businesses in the long-term.

Crucial pointers from the Nanomedicine Market report:

COVID-19 effect on the remuneration scale of the industry. Predicted growth rate of the market. Key trends in the market. Opportunities with strong profit potential. Merits and demerits of indirect and direct sales channels. Leading distributors, traders, and dealers.

Competitive Landscape:

The leading players of Nanomedicine Market, their market share, product portfolio, company profiles are covered in this report. The leading market players are analyzed on the basis of production volume, gross margin, market value, and price structure. The competitive market scenario among Nanomedicine Market players will help the industry aspirants in planning their strategies. The statistics offered in this report will be precise and useful guide to shape the business growth.

Market Segmentation:

In order to maximize marketing campaigns, promotional tactics and global and regional sales activities, the Nanomedicine Market segmentation is used to evaluate the target market into smaller parts or divisions such as product category, application, and geographical regions.

Geographical Analysis:

Nanomedicine Market Segment by Regions Consists:

North America (United States, Canada and Mexico) Europe (Germany, France, UK, Russia and Italy) Asia-Pacific (China, Japan, Korea, India and Southeast Asia) South America (Brazil, Argentina, Colombia) Middle East and Africa (Saudi Arabia, UAE, Egypt, Nigeria and South Africa)

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Key Strategic Developments:The study also includes the key strategic developments of the market, comprising R&D, new product launch, M&A, agreements, collaborations, partnerships, joint ventures, and regional growth of the leading competitors operating in the market on a global and regional scale.

Analytical Tools:The Nanomedicine Market Report includes the accurately studied and assessed data of the key industry players and their scope in the market by means of a number of analytical tools. The analytical tools such as Porters five forces analysis, SWOT analysis, feasibility study, and investment return analysis have been used to analyze the growth of the key players operating in the market.

Key Market Features:The report evaluated key market features, including revenue, price, capacity, capacity utilization rate, gross, production, production rate, consumption, import/export, supply/demand, cost, market share, CAGR, and gross margin. In addition, the study offers a comprehensive study of the key market dynamics and their latest trends, along with pertinent market segments and sub-segments.

Customization of the Report: This report can be customized as per your needs for additional data up to 3 companies or countries or 40 hours analyst support.

Table of Contents

Market Overview:This is the first section of the report that includes an overview of the scope of products offered in the global Nanomedicine market, segments by product and application, and market size.

Market Competition by Player:Here, the report shows how the competition in the global Nanomedicine market is growing or decreasing based on deep analysis of market concentrate rate, competitive situations and trends, expansions, merger and acquisition deals, and other subjects. It also shows how different companies are progressing in the global Nanomedicine market in terms of revenue, production, sales, and market share.

Company Profiles and Sales Data:This part of the report is very important as it gives statistical as well as other types of analysis of leading manufacturers in the global Nanomedicine market. It assesses each and every player studied in the report on the basis of main business, gross margin, revenue, sales, price, competitors, manufacturing base, product specification, product application, and product category.

Market Status and Outlook by Region:The report studies the status and outlook of different regional markets such as Europe, North America, the MEA, Asia Pacific, and South America. All of the regional markets researched about in the report are examined based on price, gross margin, revenue, production, and sales. Here, the size and CAGR of the regional markets are also provided.

Market by Product:This section carefully analyzes all product segments of the global Nanomedicine market.

Market by Application:Here, various application segments of the global Nanomedicine market are taken into account for research study.

Market Forecast:It starts with revenue forecast and then continues with sales, sales growth rate, and revenue growth rate forecasts of the global Nanomedicine market. The forecasts are also provided taking into consideration product, application, and regional segments of the global Nanomedicine market.

Upstream Raw Materials:This section includes industrial chain analysis, manufacturing cost structure analysis, and key raw materials analysis of the global Nanomedicine market.

Marketing Strategy Analysis, Distributors:Here, the research study digs deep into behavior and other factors of downstream customers, distributors, development trends of marketing channels, and marketing channels such as indirect marketing and direct marketing.

Research Findings and Conclusion:This section is solely dedicated to the conclusion and findings of the research study on the global Nanomedicine market.

Appendix:This is the last section of the report that focuses on data sources, viz. primary and secondary sources, market breakdown and data triangulation, market size estimation, research programs and design, research approach and methodology, and the publishers disclaimer.

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Global Nanomedicine in Central Nervous System Injury and Repair Market Research Report, Growth Trends and Competitive Analysis 2021-2027 KSU | The…

The global Nanomedicine in Central Nervous System Injury and Repair Market size is projected to grow from USD XX million in 2020 to USD XX million by 2027, at a CAGR of XX%. Increasing awareness towards strict government regulations on emission control is an opportunity for the growth of the market. However, owing to COVID-19, the sales have declined, resulting in reduced demand.

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Historical and future availability, market share, prices, trade, competition, and value chain dynamics are among the topics covered in the study. Analysts spoke to CEOs, advertisers, brand owners, vice presidents, and sales and marketing managers during the primary study. Analysts also highlighted the changing business scenario based on evidence gathered from interviews with credible sources.

Forecast period:- 2020-2025.Base year :- 2019Estimation period :-2020-2025.

Top key players: bbott, Ablynx N.V, California Life Sciences Association, CELGENE CORPORATION, Teva Pharmaceutical Industries Limited, GENERAL ELECTRIC COMPANY, Merck Sharp & Dohme Corp (a subsidiary of Merck & Co., Inc), Pfizer Inc, Nanosphere Inc, Johnson & Johnson Private Limited and BD among other domestic and global players. Get Up to 20% Discount on this Premium Report https://www.infinitybusinessinsights.com/ask_for_discount.php?id=472769

The report offers an up-to-date analysis regarding the current global market scenario, latest trends and drivers, and the overall market environment. The market is driven by the increasing demand. This market research report provides a complete competitive landscape and an in-depth vendor selection methodology and analysis using qualitative and quantitative research to forecast an accurate market growth.

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‘Robo-sapiens’ era will force 100 million workers to switch jobs by 2030, BofA says – The National

The rapid pace of technology disruption will transform workers' lives and create new professions as the global economy enters an era of robo-sapiens, according to Bank of America Securities.

This will force about 100 million workers to switch occupations by 2030.

A $14 trillion opportunity exists for the future of work, where humans and robots will collaborate, the bank said in a report.

The future of work is not zero-sum between humanity and technology. We believe humans can collaborate with and work alongside robots, rather than be displaced by them, and that technology can create more jobs than it destroys, said BofA Securities.

These new-collar jobs could emerge in sectors ranging from health care to renewables, with humans expected to have more leisure time as machines relieve people of mundane, repetitive daily tasks.

The future of work is not zero-sum between humanity and technology

Bank of America Securities

Technology, industrials, medical technology and education are among the key sectors that stand to benefit as companies upskill and retrain workers.

However, the commercial property and the legacy transport sectors face headwinds.

By 2025 alone, automation will result in a net addition of 12 million jobs as robots eliminate 85 million jobs but create 97 million new ones, according to the World Economic Forum.

The next decade will be marked by unprecedented change in the world of work, the BofA Securities report said.

Humans and machines could spend an equal amount of time completing work tasks by 2025, with the global robot installed base doubling to 5 million units compared with 2019 levels.

The field of cobots the collaboration between humans and industrial robots is a fast-growing area with a projected compound annual growth rate of 50 per cent through to 2023.

Apart from white and blue-collar work, the Covid-19 pandemic is expected to spur a boom in pink, green and new-collar jobs, BofA Securities said.

Pink-collar jobs are professions in the care economy such as doctors, nurses, psychologists, teachers and childcare providers.

Green-collar jobs involve work in the clean energy sector performed by solar engineers, wind technicians and battery experts while new-collar jobs are focused on technology, cyber security and coding.

A transforming world could lead to some truly futuristic jobs that have yet to be invented. Some of these new roles could be data privacy managers, nanomedicine surgeons, lab meat scientists, space tourist guides, freelance biohackers, AI avatar designers, 3D food printer chefs, leisure time planners, ethical algorithm programmers and brain simulation specialists, according to the report.

We are at the early stages of Eureka! Future tech, where we think the exponential growth of moonshot technology will create a new wave of professions that we have not even thought of yet, the report's authors said.

Many jobs of the future have yet to be created, they said, with 65 per cent of children starting school today expected to work in jobs that do not exist at this time.

Covid may spark rapid growth in new types of occupation, the report's authors said.

For example, companies may hire a work-from-home integration manager to ensure that new technology and equipment are in place to make remote work a success.

Organisations with a renewed focus on health and hygiene may hire office disinfectors or chief medical officers.

New occupations such as smart home designers and algorithm bias checkers who ensure algorithms do not lead to discriminatory decisions are emerging.

Around the globe, growing demand for automation, AI and digitisation will spur the need for a wide range of workers such as robot repair technicians and 3D printing engineers, said BofA Securities.

A new report by McKinsey Global Institute said the need for workers to switch occupations would lead to the reskilling of workers a post-Covid future that chief executives must prepare for.

Ageing populations, higher consumer incomes and the pandemic will drive growth in healthcare jobs while transport jobs will grow due to high demand for delivery and e-commerce, according to the McKinsey Global Institute report.

The customer service, sales, warehousing and computer-based work segments will be hit the hardest in terms of jobs lost.

People in these declining job categories will need to be retrained to take up new occupations.

The challenge is not only the large numbers but the jumps they will need to make are much higher than in the past, said Susan Lund, McKinsey Global Institute leader and a labour market expert.

We will need to figure out how to help them to transition to different career pathways. This will disproportionately affect women four times as many as men and people without college degrees, as well as young people and ethnic minorities.

While there are areas where humans can beat machines, including jobs that require creativity or social intelligence, the BofA Securities report said the risks posed by robots should not be disregarded.

Adopting technology could displace about 2 billion jobs by 2030. Up to 47 per cent of US jobs could be at risk from computerisation over the next 20 years. This figure could reach 85 per cent in emerging markets, BofA Securities said.

Emerging markets such as India and China are at the greatest risk of facing skills disruption due to the trend, according to the report.

Ethiopia, Cambodia and Bangladesh are the three countries that face the greatest risk from automation as the majority of work performed in these countries can be done by robots.

The most worrying trend is that emerging market jobs are most at risk of automation because of the low or mid-skilled nature of sectors such as manufacturing, highlighting the risk of premature deindustrialisation.

Premature deindustrialisation refers to a situation where countries hit peak manufacturing before they traverse the economic development curve sufficiently.

Economic history tells us the traditional route to prosperity has been for countries to move from an agrarian economy towards manufacturing via industrialisation, for example, the UK in the early 19th century, the US in the late 19th century and, more recently, China at the turn of the 20th century, the report said.

Bypassing industrialisation could lead to the displacement of manual labour as automation becomes more sophisticated.

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'Robo-sapiens' era will force 100 million workers to switch jobs by 2030, BofA says - The National

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