Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks – Business Wire
May 21st 2020 Posted at Human Longevity
Comments Off on Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks – Business Wire |
SAN FRANCISCO--(BUSINESS WIRE)--Atomwise, the leader in using artificial intelligence (AI) for small molecule drug discovery, announced today it has fifteen research collaborations underway with leading global universities to explore broad-spectrum therapies for COVID-19 and other coronaviruses.
Coronaviruses are RNA viruses and include the causative SARS-CoV-2 strain of the current COVID-19 global pandemic as well as MERS and SARS-CoV-1 from prior regional outbreaks. Although drug repurposing may offer a rapid response to the current outbreak, the longevity of such an approach may be limited due to the accumulation of mutations and evolution of the virus. By using predictive models and AI, Atomwise and its collaborators seek to raise the probability of success for future therapies.
Each collaborative project will develop drug candidates with demonstrable broad-spectrum capability, providing potential long-term benefit for future coronavirus outbreaks. Overall, the 15 global research efforts span a wide variety of approaches, including different mechanisms of action, a mixture of viral and human/host target proteins, and targeting conserved regions of proteins that may be recognized even in mutated strains. In addition, many proteins targeted by the academic collaborators have previously been deemed undruggable due to their unknown structure or involvement in complex protein-protein interactions. Taken together, the combination of novel approaches could expand the repertoire of therapeutic approaches available for a future outbreak.
Several projects are part of Atomwises Artificial Intelligence Molecular Screen (AIMS) program, which enables researchers to accelerate the translation of their research into treatments. In support of each collaboration, scientists at Atomwise will use AtomNet, the companys patented AI screening technology, to predict the binding of millions or billions of small molecules to a protein of interest identified by the academic researcher as a potential target for COVID-19, narrowing down to a few hundred predicted hit molecules. Atomwise then sources and ships a subset of these predicted compounds to partnering laboratories for testing biochemical potency and selectivity, advancing the most promising compounds for further development as drug candidates.
Atomwises AI screening technology is used to predict the binding of more than 10 million small molecules to a protein of interest, and far exceeds what could be accomplished through traditional laboratory screening methods, said Dr. Stacie Calad-Thomson, vice president and head of Artificial Intelligence Molecular Screen (AIMS) Partnerships at Atomwise. With Atomwises AIMS Awards program, our hope is to democratize access to AI during the early stages of preclinical drug development and enable academics to contribute to the pandemic response who might not have the opportunity otherwise.
Research partners will include:
Target
Researcher
Institute
IL-6 Signaling Pathway
Dr. Mark Fry
University of Manitoba
Nucleocapsid (N-protein)
Dr. Luana Fioriti and Dr. Eric Kandel
Columbia University
NSP15
Dr. James L. Cole
University of Connecticut
Papain-Like Protease (PLpro)
Dr. Konstantin V. Korotkov
University of Kentucky
RdRp in NSP12
Dr. Jorg Stetefeld
University of Manitoba
Spike-ACE2
Dr. Gokhan Cildir
University of South Australia
Spike-ACE2
Dr. Alexander Freiberg
University of Texas Medical Branch (UTMB) Health
Spike (heptad region)
Dr. Abdullah Algaissi
Jazan University, Saudi Arabia
Undisclosed
Dr. Hari Arthanari
Dana-Farber Cancer Institute
Undisclosed
Dr. Yogesh Gupta
University of Texas Health Science Center at San Antonio
Undisclosed
Dr. Mel Fernand Bedi, Dr. Tim Mueser, and Dr. Amanda Bryant-Friedrich
University of Toledo
Atomwise and its partners will continue to focus research efforts on broad-spectrum approaches for COVID-19 and other coronaviruses so that drug discovery solutions are applicable for this pandemic, as well as for mutations, recurrences, or other coronavirus strains that may take place in the future.
Researchers interested in applying for the AIMS Awards program or pursuing industry partnerships with Atomwise are encouraged to contact academics@atomwise.com or partner@atomwise.com for more information.
About Atomwise
Atomwise Inc. invented the first deep learning AI technology for structure-based small molecule drug discovery. Created in 2012, today Atomwise performs hundreds of projects per year in partnership with some of the worlds largest pharmaceutical and agrochemical companies, as well as more than 200 universities and hospitals in 40 countries. Atomwise has raised over $50 million from leading venture capital firms to support the development and application of its AI technology. Learn more at atomwise.com or follow @AtomwiseInc.
See the article here:
Atomwise Partners with Global Research Teams to Pursue Broad-Spectrum Treatments Against COVID-19 and Future Coronavirus Outbreaks - Business Wire
- What are longevity supplements, and are they safe? - MarketWatch - January 8th, 2021
- Love is Everywhere banners placed in Downtown Boise, ID - boisedev.com - January 8th, 2021
- Show Kindness And Volunteer More: New Book Says Improving Human Connections Can Lengthen Life - Here And Now - January 8th, 2021
- Global longevity and anti-senescence therapy market || keyplayer Senex Biotechnology, and Senolytic Therapeutics - FLA News - January 8th, 2021
- Commentary: Health experts and other San Diego leaders must unite to better coordinate pandemic response - The San Diego Union-Tribune - January 8th, 2021
- Letter to the editor: Lowry's take on climate wrong - Bryan County News - January 8th, 2021
- Too Much of This Mineral May Shorten Your Life, Study Finds | Eat This Not That - Eat This, Not That - January 8th, 2021
- The New Face of Integrated Planning and Design - D Magazine - January 8th, 2021
- Pleasant Hope facility looking to hire people to work in beef processing plant - KOLR - OzarksFirst.com - January 8th, 2021
- Indie Focus: Grief and resilience in 'Pieces of a Woman' - Los Angeles Times - January 8th, 2021
- Longevity and Anti-senescence Therapy Market Size and Growth Factors Research and Projection 2026 - Farming Sector - January 4th, 2021
- Study of More Than 1 Million People Finds Intriguing Link Between Iron Levels And Lifespan - ScienceAlert - January 4th, 2021
- Covid-19 Update Precision Medicine Software market: Poised to Garner Maximum Revenues by 2027 with major key players in the market Syapse, Allscripts,... - January 4th, 2021
- LyGenesis Receives FDA Clearance to Begin Phase 2a Trial of its Cell Therapy for Patients with End Stage Liver Disease, and also Closes $11 Million... - January 4th, 2021
- Investment in AI and nanotech surges in wake of COVID-19 - IT Brief Australia - January 4th, 2021
- 7 Ways Dogs Can Make Us Happy In The New Year - Longevity LIVE - Longevity LIVE - January 4th, 2021
- Wildlife, land-use change and health infra: Scientists identify ways of preventing next pandemic - The Tribune - January 4th, 2021
- Five macro trends set to shape the next decade - Gulf Business - January 4th, 2021
- Planet Earth Report Strange Unexplained Circles in Space to Software Map That Could Change the World Forever - The Daily Galaxy --Great Discoveries... - December 28th, 2020
- Meet the new experts of non-surgical hair transplant - Alka Verma and her salon - Infiniti Hair C... - Hindustan Times - December 28th, 2020
- Global Precision Medicine Software Market Professional Survey 2020 by Manufacturers, Share, Growth, Trends, Types and Applications, Forecast to 2026 -... - December 28th, 2020
- These entertainers in their 90s offer suggestions for good health and a long life - East Bay Times - December 28th, 2020
- The Best Champagne to Buy in 2020 - Eater - December 28th, 2020
- These Were the 15 Most-Read Singularity Hub Stories of 2020 - Singularity Hub - December 26th, 2020
- Top Wall Street analysts recommend these buys before 2020 comes to a close - CNBC - December 26th, 2020
- Fasting to Enhance Longevity? - L.A. Weekly - December 26th, 2020
- Introducing SP8CEVC: The World's First Space Technology and Human Longevity Focused Rolling Fund in Partnership with AngelList - PRNewswire - December 22nd, 2020
- Introducing the Launch of SP8CEVC's Rolling Fund in Partnership with AngelList - Salamanca Press - December 22nd, 2020
- Program Expansion to Address Increase of Impaired Driving During Global COVID-19 Pandemic - UC San Diego Health - December 22nd, 2020
- How does the human body react to being in space? - Sciworthy - December 22nd, 2020
- 2020 in Neuroscience, Longevity, and AIand What's to Come - Singularity Hub - December 22nd, 2020
- 4 Companies At The Center Of The Telemedicine And Digital Health Revolution - Seeking Alpha - December 22nd, 2020
- The 6 Best Diets That Will Make You Live Longer, Say Dietitians - Eat This, Not That - December 22nd, 2020
- The Adrenomyeloneuropathy Treatment Market to grow on an emphatic note from 2019 to 2029 - PharmiWeb.com - December 22nd, 2020
- It's good to know how others think | Preston Citizen | hjnews.com - The Herald Journal - December 22nd, 2020
- Medicine by Design symposium highlights importance of convergence in regenerative medicine and human health - News@UofT - December 22nd, 2020
- WISeCoin, the Innovative Tokenized Service of WISeKey, Authenticates People, Products and Machines Using Blockchain and AI - GlobeNewswire - December 22nd, 2020
- Healthcare Organizations Are Polluting The Air And Harming Public Health, But That Can Change - Forbes - December 22nd, 2020
- The 'Wondrous Map': Charting of the Human Genome, 20 Years Later - Medscape - December 11th, 2020
- Dont miss these breakout sessions at TC Sessions: Space 2020 - TechCrunch - December 11th, 2020
- 6 Longevity-Promoting Herbs and Spices To Add to Your Cooking Rotation - Well+Good - December 11th, 2020
- Global Stoma/Ostomy Care Market Trajectory & Analytics Report 2020: Focus on Stoma Quality of Life Paves Way for Increased Spending on... - December 11th, 2020
- Leading Healthy Aging Researcher Brian Kennedy, Ph.D., To Address Natural Health Industry On Impact Of Nutrition On Biological Age - PRNewswire - December 11th, 2020
- Biopharma Money on the Move: December 2 - 8 - BioSpace - December 11th, 2020
- Warm Up Your Content Strategy with a Human Touch - The Content Standard by Skyword - December 11th, 2020
- Bestselling Author, Jill Wright, Celebrates Feature in Thriving Women Magazine With Presale of Codes of Longevity - Press Release - Digital Journal - December 11th, 2020
- As early as Tuesday, the coronavirus vaccine arrives. Who's first in line, and what we know about who's next - The Columbus Dispatch - December 11th, 2020
- Jerry Seinfeld: Success is the enemy of irritability and crankiness how to stay productive and motivated - CNBC - December 11th, 2020
- Oxford Covid vaccine to be combined with Sputnik jab for trial - The Guardian - December 11th, 2020
- Stop the rain on human rights EURACTIV.com - EURACTIV - December 11th, 2020
- Welbeck Children's partners with National Forest - The Bookseller - December 11th, 2020
- Is the great stagnation over? - The Week - December 5th, 2020
- BioAge Raises $90M to Treat Aging and Age-related Diseases - GlobeNewswire - December 5th, 2020
- Tigerlily Foundation to Lead Historic Special Session on Health Equity, Collaboration and Partnership at the 2020 San Antonio Breast Cancer Virtual... - December 5th, 2020
- Pill to reverse ageing in 30 years? Why not, says Harvard professor Dr David Sinclair - Hindustan Times - December 5th, 2020
- Ciara and ex-Lululemon CEO launch new clothing brand with 'more to it than fashion' - CNBC - December 5th, 2020
- Re-Inventing the Wheel: How CEOs Are Driving the Sustainable Tire of the Future - Triple Pundit - December 5th, 2020
- What is the secret to aging well? - MarketWatch - December 5th, 2020
- NUS-led team uncovers molecule that promotes muscle health when magnetised - Newswise - December 5th, 2020
- Lifetime perspective on alcohol and brain health - The BMJ - December 5th, 2020
- Stem Cell Market Analysis By Industry Value, Market Size, Top Companies And Growth Forecast To 2027 - Cheshire Media - December 5th, 2020
- Go with the Flowbee: George Clooney reveals how he cuts his hair - The Guardian - December 5th, 2020
- Vaccines against COVID-19 will have side effects that's a good thing - Kiowa County Press - December 5th, 2020
- Larry Hunter, former Ann Arbor council member and Black Panther, dies at 69 - MLive.com - November 23rd, 2020
- Life Longevity and the pursuit of harmony - WKBW-TV - November 21st, 2020
- Migrating species tend to 'live fast and die young' - UPI News - November 21st, 2020
- Fountain of youth? The science behind living longer - KGUN - November 21st, 2020
- Longevity and Anti-senescence Therapy Market: Opportunities, Demand and Forecasts, size COVID-19 2023 - ICOTodayMagazine - November 21st, 2020
- Global Precision Medicine Software Market in-Depth Analysis, Key Players, Challenges, Segmentation and Forecasts to 2027. - The Think Curiouser - November 21st, 2020
- Human ageing process biologically reversed in world first - Telegraph.co.uk - November 21st, 2020
- The known unknowns of T cell immunity to COVID-19 - Science - November 21st, 2020
- Now is the time for climate action - HubcitySPOKES.com - November 21st, 2020
- What must we teach The Next Generation? - The Business Times - November 21st, 2020
- Korea plans up to W10tr investment for biohealth by 2023 - The Korea Herald - November 21st, 2020
- Asymmetrex Publishes the First Report of Immortal DNA Strands in Human Stem Cells - PR Web - November 21st, 2020
- 20 Years of Observing Earth From the Space Station An Extraordinary View From Outer Space - SciTechDaily - November 21st, 2020
- Global AI Medicine Software Market Analysis of Key Players, Type, Application, Demand and Consumption By 2026 - Stock Market Vista - November 7th, 2020
- 4 Reasons To Use Cannabis For Treating Women's Health Issues - Longevity LIVE - November 7th, 2020
- Global Adrenomyeloneuropathy Treatment Market Size, Share, Trends, CAGR by Technology, Key Players, Regions, Cost, Revenue and Forecast 2020 to 2025 -... - November 7th, 2020
- US listing set to support and accelerate ongoing development of 4D Pharma's live biotherapeutics - BioPharma-Reporter.com - November 7th, 2020
Recommendation and review posted by Alexandra Lee Anderson
Both comments and pings are currently closed.