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Expert Reveals Key Information That Men Need to Know About Testosterone – KMJ Now

Studies have shown that men over the age of 65 may benefit from taking the hormone testosterone. According toDr. Mirkin.comstudies have shown that testosterone increases bone density, raises hemoglobin levels in men with anemia, and improves sexual function. Reviews were mixed on whether testosterone improved heart health, however.

According to a study published in JAMA, testosterone significantly increased plaque in the arteries that lead to the heart. However, another study found that using testosterone gel for threeyears reduced the rate of heart attacks in men by 25%.

Dr. David B. Samadhi, a board-certified urologist, a Newsmax contributor, the director of Mens Health and Urologic Oncology at St. Francis Hospital in Roselyn, New York, and the author ofThe Ultimate MANual: Dr. Samadhis Guide to Mens Health and Wellness, tells Newsmaxthat the hormone is quite often overused because of its macho man association.

Of course, testosterone is a necessary and potent chemical messenger that indeed directly influences many physiological processes in a mans body, Samadi explains. Testosterone influences mens sex drive, bone mass, fat distribution, and muscle mass and strength, among other things. What man doesnt want to look strong, muscular, and ready for sex at the drop of a hat?

But the expert warns that advertisers understand this and play upon this notion by touting unproven products.

I remember a 2014 Time magazine cover story titled, Manopause that featured aprovocative cover and delved into the clever marketing and tons of money spent into making men believe that more testosterone is their quick fix and best remedy for remaining youthful and virile.

Thats why on any given day of the year, you see or hear commercials hawking a testosterone supplement promising to bring back mens youthful vigor, says Samadi.

As a urologist and prostate cancer surgeon, my advice to men is stay away from any spa, TV ads or any nonmedical person selling supplements for low T, he says. Testing testosterone and getting an accurate measurement can be tricky since levels fluctuate during the day.Only a doctor should be checking a mans testosterone levels. Testosterone levels should be checked before 9:00 a.m. when levels are their highest. Also, two tests are necessary to check for accuracy.

Samadi says that testosterone deficiency may or may not have symptoms.

But I can tell you, men with low T are like a car thats run out of gas they may be depressed, lack energy, motivation, and self-confidence, have reduced muscle mass and increased fat mass, loss of body hair, hot flashes, fewer spontaneous erections or difficulty sustaining erections, and have little interest in sex, he adds.

For any man who does have low testosterone, the benefits of hormone replacement therapy usually outweigh the risk., advises the expert. When men are selected correctly for using this therapy, it can be very helpful. Testosterone therapy for these men can help maintain muscle mass, slow osteoporosis, boost energy and stamina, and bring back their love life. But, I stress, its critical these men must be under surveillance with their doctor. Testosterone levels must be checked regularly as one possible side effect of testosterone therapy is it could stimulate the growth of prostate cancer cells.

Men who think they have low T, should talk to their doctor, get tested, and if therapy is needed, follow-up with their doctor periodically to have testosterone levels checked making sure the therapy is not causing any health problems, says Samadhi.

2021 NewsmaxHealth. All rights reserved.

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Pham named Guy and Ella Mae Magness Professor of Medicine – Washington University School of Medicine in St. Louis

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Rheumatologist develops nanomedicine approaches for inflammatory diseases

Christine Pham, MD, works in her lab in 2017. A rheumatologist who specializes in nanomedicine approaches to inflammatory diseases, Pham has been named the inaugural Guy and Ella Mae Magness Professor of Medicine at Washington University School of Medicine in St. Louis.

Christine Pham, MD, director of the Division of Rheumatology at Washington University School of Medicine in St. Louis, has been named the inaugural Guy and Ella Mae Magness Professor of Medicine.

Pham was chosen for the honor in recognition of her work involving nanomedicine approaches in the treatment of inflammatory diseases and the role of biomolecules known as proteases in inflammatory processes. The Department of Medicine established the Guy and Ella Mae Magness Professorship in Medicine in 2018 with proceeds from the Ella Mae Magness Trust.

I am delighted to recognize Dr. Phams accomplishments with this professorship named for two noted health professionals and graduates of Washington University, said Chancellor Andrew D. Martin. Dr. Guy and Ella Mae Magness worked tirelessly to promote public health, and their dedication to medicine and to our community is reflected in Dr. Pham. She has distinguished herself both in her research on the role of neutrophil proteases in inflammatory arthritis and her commitment to mentoring and supporting junior faculty.

Pham will be officially installed when the COVID-19 pandemic is under control. She will be installed by David H. Perlmutter, MD, executive vice chancellor for medical affairs, the George and Carol Bauer Dean of the School of Medicine, and the Spencer T. and Ann W. Olin Distinguished Professor; and Victoria J. Fraser, MD, the Adolphus Busch Professor of Medicine and head of the Department of Medicine.

Also a professor of pathology & immunology, Pham more recently has focused on nanomedicine approaches for various inflammatory conditions including rheumatoid arthritis, a chronic, incapacitating disease involving painful, swollen joints. Nanomedicine involves using tiny transport particles for a concentrated delivery of therapeutics directly to specific sites such as the joints. Nanoparticle formulations also help protect unstable drugs from degradation in the bloodstream, thereby unlocking the potential of new kinds of therapeutics. Pham employs a nanocomplex that protects an unstable experimental arthritis drug and efficiently delivers it to the joints, where it suppresses specific and harmful pathways that cause inflammation in diseased tissues without affecting the global immune system.

Christine Pham exemplifies faculty who are the foundation of what we do at the School of Medicine today and are poised to do tomorrow, Perlmutter said. She is an outstanding physician-scientist with expertise in immunology, rheumatology and translational approaches to inflammatory arthritis and autoimmune diseases. She draws upon this broad expertise to promote multidisciplinary research in inflammatory diseases with the goal of developing better treatments for patients.

Pham directs Washington Universitys Rheumatic Diseases Research Resource-Based Center, which provides resources to accelerate basic and translational research into rheumatic diseases, aiming to improve treatment for people suffering from rheumatic diseases such as arthritis, lupus and vasculitis, an inflammation of the blood vessels.

Before moving into nanomedicine, Pham explored the role of proteases enzymes that break down proteins produced by certain white blood cells in inflammatory diseases. Her laboratory cloned and characterized the protease cathepsin C. Her work led to the development of cathepsin C inhibitors that are in clinical trials for a form of chronic inflammatory lung disease.

Dr. Christine Phams work on the role of innate and adaptive immune responses in various inflammatory processes has led to the identification of new therapeutic targets for these diseases, Fraser said. She is an esteemed member of the Washington University community who has a deep commitment to innovative multidisciplinary research. She is an outstanding mentor and champion for residents, fellows and junior faculty. She is well-deserving of this recognition.

Guy N. Magness, MD, (1899-1982) earned his medical degree at the School of Medicine in 1928. He began his career as a school physician and in 1931 rose to become director of medical services for University City Public Schools, where he served for 40 years. He also held the position of director of health for University City from 1952 to 1981, gaining recognition as a leader in the field of health problems in public education. In 1963, he co-chaired a polio vaccination drive, and more than a million St. Louisans were immunized as a result. He was in the Army Medical Corps in World War II and retired from the Army reserve as a colonel.

Ella Mae Magness (1905-2000) was Missouris director of public health from the late 1930s to the early 1940s. In the late 1940s, she was the western regional director of public health covering seven states. She earned a certificate in nursing in 1928 and a bachelors degree in nursing in 1937, both from Washington University School of Nursing. She earned a masters degree in public health from Columbia University in New York, and she served in the U.S. Armys Nurse Corps during World War II, attaining the rank of lieutenant colonel.

Washington University School of Medicines 1,500 faculty physicians also are the medical staff of Barnes-Jewish and St. Louis Childrens hospitals. The School of Medicine is a leader in medical research, teaching and patient care, ranking among the top 10 medical schools in the nation by U.S. News & World Report. Through its affiliations with Barnes-Jewish and St. Louis Childrens hospitals, the School of Medicine is linked to BJC HealthCare.

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Global NANOTECHNOLOGY IN MEDICAL APPLICATIONS Statistics, CAGR, Outlook, and Covid-19 Impact 2016 The Bisouv Network – The Bisouv Network

Nanotechnology in Medical Applications: The Global Market

This report discusses the implications of technology and commercial trends in the context of the current size and growth of the pharmaceutical market, both in global terms and analyzed by the most important national markets. The important technologies supporting nanomedicine are reviewed, and the nature and structure of the nanomedicine industry are discussed with profiles of the leading 60+ companies, including recent merger and acquisition (M&A) activity. Five-year sales forecasts are provided for the national markets including the major therapeutic categories of products involved. Specific product categories quantified include diagnostics, cancer, CNS, anti-infective agents, cardiovasculars and anti-inflammatories.

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Report Includes:

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An overview of the global markets for nanotechnology used in medical applications

Analyses of global market trends, with data from 2016, estimates for 2017, and projections of compound annual growth rates (CAGRs) through 2022

A review of technologies involved, in-depth analysis of applications in practice, and evaluation of future or potential applications

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Information on many significant products in which the nano dimension has made a significant contribution to product effectiveness

A look at the regulatory environment, healthcare policies, demographics, and other factors that directly affect nanotechnology used in medicine

Analysis of the markets dynamics, specifically growth drivers, inhibitors, and opportunities

Coverage of strategies employed by companies specializing in nanomedicine to meet the challenges of this highly competitive marketSummary

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Nano-enabled medical products began appearing on the market over a decade ago, and some have become best-sellers in their therapeutic categories. The principal areas in which nanomedical products have made an impact are cancer, CNS diseases, cardiovascular disease and infection control. The Summary Table gives estimates of the historical and current markets for these nanomedicine areas with a forecast through 2022.

The U.S. market is by far the largest in the global nanomedicine market and is set to continue to dominate the world marketplace; however, other national markets are expected to increase their shares over the next five years.

Reasons for Doing the Study

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Nanomedicine is already an established market. Unlike some other potential applications of nanotechnology, which are still largely experimental, nanomedicine has already produced some significant products in which the nano dimension has made a significant contribution to product effectiveness. Now that aspects of the nanomedicine market are established, it is appropriate to review the technology, see its practical applications so far, evaluate the participating companies and look to its future.ABLYNX NV

ABRAXIS BIOSCIENCE (CELGENE)

APHIOS CORP.

BIOFORCE NANOSCIENCES HOLDINGS INC.

BIO-GATEAG

CALANDO PHARMACEUTICALS INC.

C SIXTY INC. (ARROWHEAD PHARMACEUTICALS)

ELAN (ALKERMES CORP.)

FARFIELD SCIENTIFIC (BIOLIN SCIENTIFIC AB)

IGI LABORATORIES (TELIGENT INC.)

KEREOS INC.

KEYSTONE NANO INC.

KLEINDIEK NANOTECHNIKGMBH

LABOPHARM (PALADIN LABS)

LIPLASOME PHARMA APS

MAGFORCE NANOTECHNOLOGIES

MAGNAMEDICS GMBH

MICROFLUIDICS CORP.

MOLECULAR PROFILES (JUNIPER PHARMA SERVICES)

NANOBIO CORP.

NANOBIOTIX

NANOCARRIER CO. LTD

NANOCOPOEIA, INC.

NANOCYTE INC.

NANOLOGIX INC.

NANOMED PHARMACEUTICALSINC.

NANOMIX INC.

NANOPHARM AG

NANOSPECTRA BIOSCIENCESINC.

NANOSPHERE INC. (LUMINEX CORP.)

NANOSTRUCTURES INC.

NANOSYN INC.

NANOTHERAPEUTICS INC.

NANOTROPE INC.

NANOVIRICIDES INC

NUCRYST PHARMACEUTICALS

NUTRALEASE

ORTHOVITA INC. (STRYKER CORP.)

PIONEER SURGICAL TECHNOLOGY (RTI SURGICAL)

PSIVIDA LTD.

SOLUBEST LTD

STARPHARMA

TECANGROUP LTD.

TRANSGENEX NANOBIOTECH INC.

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Healthcare Nanotechnology Market Competitive Research And Precise Outlook 2021 To 2026 KSU | The Sentinel Newspaper – KSU | The Sentinel Newspaper

The report is designed to provide a holistic view of the Healthcare Nanotechnology market 2021-2026. It provides the industry overview with market growth analysis with a historical & futuristic perspective for the following parameters; revenue, demands, and supply data (as applicable). High-level interpretation of Healthcare Nanotechnology market attributes using proprietary tools such as the Penetration Mapping Index, and other successful representational tools such as Porters Five Forces Analysis, SWOT, PESTEL, Ansoffs Matrix, etc. Regional estimates and forecasts & trend analysis for each country and region are also available in the study. The impact of the COVID-19, and also forecasts its recovery post-COVID-19. The report also presents forecasts for Healthcare Nanotechnology investments from 2021 till 2026.

Top Companies in the Global Healthcare Nanotechnology Market:Amgen, Teva Pharmaceuticals, Abbott, UCB, Roche, Celgene, Sanofi, Merck & Co, Biogen, Stryker, Gilead Sciences, Pfizer, 3M Company, Johnson & Johnson, Smith & Nephew, Leadiant Biosciences, Kyowa Hakko Kirin, Shire, Ipsen, Endo International.

Over the next five years, the Healthcare Nanotechnology market will register a 9.9% CAGR in terms of revenue, the global market size will reach US$ 251360 million by 2025, from US$ 172260 million in 2019.

Market OverviewIt is defined as the study of controlling, manipulating, and creating systems based on their atomic or molecular specifications. As stated by the US National Science and Technology Council, the essence of nanotechnology is the ability to manipulate matters at atomic, molecular and supra-molecular levels for creation of newer structures and devices. Generally, this science deals with structures sized between 1 to 100 nanometer (nm) in at least one dimension and involves in modulation and fabrication of nanomaterials and nanodevices.

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Market InsightsNanotechnology is becoming a crucial driving force behind innovation in medicine and healthcare, with a range of advances including nanoscale therapeutics, biosensors, implantable devices, drug delivery systems, and imaging technologies.The classification of Healthcare Nanotechnology includes Nanomedicine, Nano Medical Devices, Nano Diagnosis, and Other product. And the sales proportion of Nanomedicine in 2017 is about 86.5%, and the proportion is in increasing trend from 2013 to 2017.

The Healthcare Nanotechnology market can be divided based on product types and Its sub-type, major applications and Third-Party usage area, and important regions.

This report segments the global Healthcare Nanotechnology Market based on Typesare:NanomedicineNano Medical DevicesNano DiagnosisOthers

Nanomedicine has the highest percentage of revenue by type, with more than 86% in 2019.

Based on Application, the Global Healthcare Nanotechnology Market is Segmented into:AnticancerCNS ProductAnti-infectiveOthers

According to the application, anticancer and CNS products accounted for 17.56% and 22.70% of the market in 2019 respectively.

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Regions are covered By Healthcare Nanotechnology Market Report 2021 to 2026.

North America, Europe, China, Japan, Southeast Asia, India.North America (USA, Canada, and Mexico).Europe (Germany, France, UK, Russia and, Italy).Asia-Pacific (China, Japan, Korea, India and, Southeast Asia).

The Total Addressable Market (TAM) For estimating the market size two approaches are used: Bottom-up and Top-down approach. In the Bottom-up approach, the consumption of in the various segments is taken into account. The regional, segment-wise, and end-user uptake/consumption is taken into account for this approach. This is then totaled to arrive at the TAM for this approach. In the Top-down approach, the company-wise production in terms of both value and volume is taken into account and totaled for arriving at the TAM. This data is then bifurcated based on the consumption in the various market segments.

Significant Features that are under Offering and Key Highlights of the Reports:

-Detailed overview of Healthcare Nanotechnology Market-Changing the Healthcare Nanotechnology market dynamics of the industry-In-depth market segmentation by Type, Application, etc.-Historical, current, and projected Healthcare Nanotechnology market size in terms of volume and valueRecent industry trends and developments-Competitive landscape of Healthcare Nanotechnology Market-Strategies of key players and product offerings-Potential and niche segments/regions exhibiting promising growth.

Frequently Asked Questions about the Healthcare Nanotechnology market:

What are the recent developments and government policies? What are the top trends in the Healthcare Nanotechnology market? What is the growth rate of the market? Which Is the Most potential market segment? Which are the top industry players in the Healthcare Nanotechnology market? Which region would offer high growth for vendors in themarket?

The report has 150 tables and figures browse the report description and TOChttps://www.marketinsightsreports.com/reports/02012579460/global-healthcare-nanotechnology-market-growth-status-and-outlook-2021-2026?Mode=46

Customization of the Report: This report can be customized as per your needs for additional data up to 5 companies or 5 countries or nearly 40 analyst hours.

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MarketInsightsReportsprovides syndicated market research on industry verticals includingHealthcare, Information and Communication Technology (ICT), Technology, and Media, Chemicals, Materials, Energy, Heavy Industry, etc.MarketInsightsReportsprovides global and regional market intelligence coverage, a 360-degree market view which includes statistical forecasts, competitive landscape, detailed segmentation, key trends, and strategic recommendations.

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Healthcare Nanotechnology (Nanomedicine) Market Size 2021, Statistics, Trends, Regional Analysis by Key Players | Industry Forecast to 2027 The…

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Healthcare Nanotechnology (Nanomedicine) Market was valued at USD 156.40 Billion in 2019 and is projected to reach USD 449.10 Billion by 2027, growing at a CAGR of 14.10% from 2020 to 2027.

The Healthcare Nanotechnology (Nanomedicine) Market report published by Verified Market Research offers an industry-wide assessment of the Healthcare Nanotechnology (Nanomedicine) market that contains the key factors contributing to the growth of the Healthcare Nanotechnology (Nanomedicine) industry. The latest Healthcare Nanotechnology (Nanomedicine) market research report provides an in-depth analysis of the micro and macroeconomic indicators influencing the development of the world market in the forecast period 2021-2027

The current trends in the Healthcare Nanotechnology (Nanomedicine) market combined with a variety of growth opportunities, key drivers, restraints, challenges, and other critical aspects have been clearly set out in the Healthcare Nanotechnology (Nanomedicine) market report. Additionally, the report takes into account various market dynamics, which in turn creates a variety of development prospects for the major players in the Healthcare Nanotechnology (Nanomedicine) industry.

The latest report is the latest study to offer 360 coverage of the Healthcare Nanotechnology (Nanomedicine) industry, which has been hit by the negative economic impact of the COVID-19 outbreak since the beginning of this year.

The Main Companies Featured in this Report are:

Sanofi SA Pfizer Inc. Celgene Corporation Luminex Corporation Taiwan Liposome Company Ltd.

Overview of the Healthcare Nanotechnology (Nanomedicine) report:

The Healthcare Nanotechnology (Nanomedicine) market has been broadly segmented to give readers a deeper understanding of the various facets and characteristics of the market. The size of the market for new entrants and incumbents has been assessed using a variety of analytical tools including SWOT analysis, investment valuation, and Porters Five Forces analysis. In addition, the authors of the report in the study assessed the financial situation of the most important companies operating in this sector. They provided important information on gross profit, share of sales, sales volume, production costs, individual growth rate and many other financial metrics of these competitors.

Healthcare Nanotechnology (Nanomedicine) Market Report Scope

Healthcare Nanotechnology (Nanomedicine) Market Segmentation

Healthcare Nanotechnology (Nanomedicine) Market By Application

Drug Delivery Biomaterials Active Implants Diagnostics Imaging Tissue Regeneration Other

Global Healthcare Nanotechnology (Nanomedicine) Market By Disease

Cardiovascular Diseases Oncological Diseases Neurological Diseases Orthopedic Diseases Infectious Diseases Other

Different industry analysis tools such as SWOT and Porters five techniques have been used for examining the important aspects of the Healthcare Nanotechnology (Nanomedicine) market. Moreover, different development plans and policies, rules and regulations are also incorporated in the research report. For a stronger and effective outlook of the Healthcare Nanotechnology (Nanomedicine) market, this report has been elucidated with effective info-graphics such as graphs, charts, tables and pictures.

The Healthcare Nanotechnology (Nanomedicine) market have been examined across several global regions such as North America, Latin America, Middle East, Asia-Pacific, Africa and Europe. The degree of competition among top key players has been described by presenting all-informative data of global key players. Furthermore, it makes use of graphical presentation techniques for presenting the essential facts during study of Healthcare Nanotechnology (Nanomedicine) market. Collectively, this innovative research report helps to make well informed business decisions in the businesses.

Visualize Healthcare Nanotechnology (Nanomedicine) Market using Verified Market Intelligence:-

Verified Market Intelligence is our BI enabled platform for narrative storytelling of this market. VMI offers in-depth forecasted trends and accurate Insights on over 20,000+ emerging & niche markets, helping you make critical revenue impacting decisions for a brilliant future.

VMI provides a holistic overview and global competitive landscape with respect to Region, Country, and Segment, and Key players of your market. Present your Market Report & findings with an inbuilt presentation feature saving over 70% of your time and resources for Investor, Sales & Marketing, R&D, and Product Development pitches. VMI enables data delivery In Excel and Interactive PDF formats with over 15+ Key Market Indicators for your market.

Important Highlights:

*** The report provides actionable information about the production capacity, estimated growth, and revenue of the regional market that has accumulated over the forecast period.

*** The report provides key information related to market dynamics such as product price patterns, total revenue generated and expected growth rate.

*** The report highlights the spectrum of competition in the Healthcare Nanotechnology (Nanomedicine) market and focuses on the company profiles of the major competitors in the market.

*** The report highlights the product portfolios along with the respective specifications and uses of those products by each market participant.

*** In addition, the production capacities, gross margins, manufacturing costs, pricing models and sales shares of these market participants were discussed.

Thank you for reading our report. The report can be adapted according to customer requirements. Please contact us to learn more about the report.

About Us: Verified Market Research

Verified Market Research is a leading Global Research and Consulting firm that has been providing advanced analytical research solutions, custom consulting and in-depth data analysis for 10+ years to individuals and companies alike that are looking for accurate, reliable and up to date research data and technical consulting. We offer insights into strategic and growth analyses, Data necessary to achieve corporate goals and help make critical revenue decisions.

Our research studies help our clients make superior data-driven decisions, understand market forecast, capitalize on future opportunities and optimize efficiency by working as their partner to deliver accurate and valuable information. The industries we cover span over a large spectrum including Technology, Chemicals, Manufacturing, Energy, Food and Beverages, Automotive, Robotics, Packaging, Construction, Mining & Gas. Etc.

We, at Verified Market Research assist in understanding holistic market indicating factors and most current and future market trends. Our analysts, with their high expertise in data gathering and governance, utilize industry techniques to collate and examine data at all stages. They are trained to combine modern data collection techniques, superior research methodology, subject expertise and years of collective experience to produce informative and accurate research.

Having serviced over 5000+ clients, we have provided reliable market research services to more than 100 Global Fortune 500 companies such as Amazon, Dell, IBM, Shell, Exxon Mobil, General Electric, Siemens, Microsoft, Sony and Hitachi. We have co-consulted with some of the worlds leading consulting firms like McKinsey & Company, Boston Consulting Group, Bain and Company for custom research and consulting projects for businesses worldwide.

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Comprehensive Analysis On Nanomedicine Market Based On Types And Application The Bisouv Network – The Bisouv Network

The Nanomedicine market report provides a detailed analysis of the emerging trends, opportunities, and as well as the challenges in the market. This extensive report sheds light on the latest developments, market drivers, and competitive analysis to help the new entrants and emerging players to make crucial decisions.

Besides this, the market research report presents insights on consumer behavior, regulatory policies, and supply & demand scenario to provide a holistic view of the market. The primitive aim of the report is to represent the critical data and figures of the market concisely and layout top winning strategies to aid industry players to leverage their market position.

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The dedicated research team has included Porters Five Point Force analysis to tailor the Nanomedicine Market. They have conducted interviews with industry experts to provide accurate predictions and better insights in a detailed manner. The research report covers the latest advancements that have overhauled the market dynamics while examined the threats which has impacted the overall market.

Key Answers Captured in the Study are

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Important Features that are under offering & key highlights of the report:

Detailed overview of Nanomedicine

Changing market dynamics of the industry

In-depth market segmentation by Type, Application, etc.

Historical, current, and projected market size in terms of volume and value

Recent industry trends and developments

Competitive landscape of Nanomedicine

Strategies of key players and product offerings

Potential and niche segments/regions exhibiting promising growth

A neutral perspective towards Nanomedicine performance

Market players information to sustain and enhance their footprint

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Research Objectives

To analyze and forecast the Worldwide Nanomedicine, in terms of value and volume.

Which segment has the potential to gain the highest market share?

To help decision-makers from a new offer perspective and benchmark existing marketing strategy.

Correlate cost structure historical data with key business segments.

Analyze marketing contribution and customer acquisition by up-selling and cross-selling.

Identifying Influencing factors keeping Worldwide Nanomedicine Intense, factored with periodic analysis of CR4 & CR8 concentration ratio & HHI Index.

Important Features that are under offering & key highlights of the report:

1) Does the study cover COVID-19 Impact Analysis and its effect on Growth %?

Yes, the overall industry has seen quite a big impact due to slowdown and shutdown in the production line & supply chain. The study covers a separate qualitative chapter on COVID-19 Impact analysis. Additionally, it also provides before and after the scenario of COVID-19 on sales growth & market size estimation to better analyze the exact scenario of the industry.

2) How companies are selected or profiled in the report?

List of some players that are profiled in the report include:

CombimatrixAblynxAbraxis BioscienceCelgeneMallinckrodtArrowhead ResearchGE HealthcareMerckPfizerNanosphereEpeius BiotechnologiesCytimmune SciencesNanospectra Biosciences

Usually, we follow NAICS Industry standards and validate company profile with product mapping to filter relevant Industry players, furthermore the list is sorted to come up with a sample size of at least 50 to 100 companies having greater topline value to get their segment revenue for market estimation.

** List of companies mentioned may vary in the final report subject to Name Change / Merger etc.

3) Can we add or profiled a new company as per our needs?

Yes, we can add or profile a new company as per client need in the report, provided it is available in our coverage list as mentioned in answer to Question 1 and after feasibility run, final confirmation will be provided by the research team checking the constraints related to the difficulty of survey.

4) Can we narrow the available business segments?

Yes, depending upon the data availability and feasibility check by our Research Analyst, a further breakdown in business segments by end-use application or product type can be provided (If applicable) by Revenue Size or Volume*.

Nanomedicine market segmentation

The Study is segmented by following Product Type:

Quantum dotsNanoparticlesNanoshellsNanotubesNanodevices

Major applications/end-users industry are as follows:

Segmentation encompasses oncologyInfectious diseasesCardiologyOrthopedicsOthers

5) Can a specific country of interest be added? What all regional segmentation covered?

Yes, Country-level splits can be modified in the study as per objectives. Currently, the research report gives special attention and focus on the following regions:

North America [United States, Canada, Mexico], Asia-Pacific [China, India, Japan, South Korea, Australia, Indonesia, Malaysia, Philippines, Thailand, Vietnam], Europe [Germany, France, UK, Italy, Russia, Rest of Europe], South America [Brazil, Argentina, Rest of South America], Middle East & Africa [GCC Countries, Turkey, Egypt, South Africa, Rest of the Middle East & Africa]

** One country of specific interest can be included at no added cost. For inclusion of more regional segment quotes will vary.

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Ponce Therapeutics Inc. Commences First R & D Program in Anti-Aging Products for Skin – PRNewswire

MIAMI, Feb. 8, 2021 /PRNewswire/ -- Ponce Therapeutics, Inc. ("Ponce"), a company leveraging the growing scientific knowledge surrounding the aging process to develop anti-aging technologies, has now become operational with the launching of its first R & D program, targeting aging-associated skin disorders. The Company has secured laboratory space in Houston, TX, and has hired its first scientists for executing their R & D plan targeting the elimination of p16-expressing cells in the skin. The cell proliferation inhibitor, p16, is highly expressed in both senescent cells and in in situ carcinoma (Bowen's Disease), which will be the focus of Ponce's efforts for first product approval.

Rapha Capital Management, LLC (https://www.raphacap.com), an investment management firm located in Miami, Florida, through Rapha Capital Investment XIII, LLC ("RCI XIII") (an entity managed by Rapha Capital), led Ponce's recently closed Convertible Note financing. The $1,500,000 financing will be used to transition Ponce into an operational company and begin execution of Ponce's R & D plan. With the close of the Convertible Note financing, Kevin Slawin, founder and President of Rapha Capital Management, added the title of Executive Chairman, to his CEO role at Ponce.

Rapha Capital is an investment management firm focused on making strategic investments in early stage, non-public biotechnology companies, through special purpose joint venture entities which it manages. Rapha Capital was founded by its President, Kevin Slawin, M.D., a successful and experienced oncologic and robotic surgeon. After leaving practice, Dr. Slawin has been serving as a biotech consultant, investor, and founder, focusing on disruptive technologies in oncology, T cells and immunotherapy, and other breakthrough healthcare technologies. He is the founder of Bellicum Pharmaceuticals, Inc.("Bellicum"), a publicly traded company listed on NASDAQ, leading Bellicum to a successful $161 million IPO in December, 2014. He also plays a guiding role in several of the investments managed by Rapha Capital in certain companies, serving as a board member at 3DBio Therapeutics, Inc. (https://3dbiocorp.com/), FIZE Medical, Inc. (www.fizemedical.com), and Demeetra AgBio, Inc. (www.demeetra.com).

Kevin Slawin, MD is the founder of Ponce, and will serve as the Chairman and CEO. David Spencer, PhD. is the founding Chief Technology Officer. Ponce Therapeutics, Inc. reunites the team that founded Bellicum Pharmaceuticals and took it public in 2014 with a $55 million crossover Series C and a $161 million IPO. The team is retooling their original cell control technology with state-of-the-art advances towards their new goal of creating anti-aging products with a solid underlying scientific basis that actually work.

"The science of aging has continued to mature and can now provide a scientific basis for technologies to reverse the aging process in humans. Proof of concept data in animal models demonstrates that removal of senescent cells from organs improves their function and imbues them with a more youthful profile. Targeting p16-expressing cells for apoptotic elimination is one approach to removing senescent cells from the body and is also a valid approach to targeting Bowen's disease of the skin, which also expresses high levels of p16, profile," said Dr. Slawin. "I'm excited to begin work in the anti-aging space, which I believe will quickly rival oncology in both value and interest" he added. "Given our greater than two-decade animal model and clinical experience with regulated cell signaling and cell survival, along with recent advances in non-viral gene delivery platforms, we are now poised to leverage an increasingly detailed, mechanistic understanding of aging to arrest or even reverse it," added Dr. Spencer.

About Rapha Capital Management, LLC Rapha Capital Management, LLC is an investment management firm located in Miami, Florida, focusing on strategic investments in early stage, non-public biotechnology companies. Rapha Capital was founded by its President, Kevin Slawin, MD, a successful and experienced oncologic and robotic surgeon, biotech consultant, investor, and founder focusing on technologies in oncology, T cells and immunotherapy, as well as other breakthrough healthcare technologies. He is the founder of Bellicum Pharmaceuticals, Inc. (NASDAQ: BLCM). He is co-Inventor of the FDA,-approved "prostate health index (phi)" test licensed and marketed by Beckman Coulter and utilized around the world. He has published extensively in top medical and scientific journals including theJournal of the American Medical Association (JAMA), Journal of the National Cancer Institute (JNCI), and the New England Journal of Medicine (NEJM). He has also been routinely listed in America's Top Doctors for Cancer (Castle Connolly Medical) and The Best Doctors in America (Woodward/White). In 2003, he was awarded the F. Brantley Scott, Jr., Award for Innovation and Creativity in Urology.

About Ponce Therapeutics, Inc.Ponce Therapeutics "Anti-aging Technologies Based on Real Science and Developed by Real Scientists" - Ponce Therapeutics is leveraging the growing scientific knowledge surrounding the process of aging to develop its first state-of-the-art biotechnology platform to restore the youthful balance of aged or "senescent" and young cells in the skin, targeting the p16-expressing senescent cells for elimination. This provides a "reboot" of one's genetic program to turn the clock on one's skin back to its youthful exuberance. Targeting p16 will also potentially allow targeting of Bowen's disease as the regulatory pathway for approval. While initially focused on skin, Ponce is planning to develop a wide-ranging portfolio of anti-aging products based on the best science in the nascent anti-aging field. Ponceis headquartered in Miami, Florida with research facilities located in Houston, TX. For more information, visitwww.poncethera.comor email [emailprotected].

For more information about Ponce Therapeutics, Inc., email [emailprotected] or visit https://www.poncethera.com

For more information about Rapha Capital Management, email [emailprotected]or visit https://www.raphacap.com

SOURCE Rapha Capital Management, LLC and Ponce Therapeutics, Inc.

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COVID-19 the new disease of growing old, hastening the work of anti-aging scientists – National Post

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The scientists are searching for drugs and diet supplements that could tweak human biology to better withstand the ravages of time

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Its one of the curiosities of the COVID-19 pandemic.

In much of Africa, amidst widespread poverty and with a limited health-care infrastructure, the pandemic has actually taken less of a death toll than in rich countries like Canada.

The reasons for that seeming contradiction are not yet totally clear, but Colin Farrelly points to one likely explanation: the continents markedly youthful population.

The COVID-19 pandemic is a highly fatal pandemic largely because of population aging, notes Farrelly, a Queens University professor who has a new journal paper on the topic. Our success in delaying death in late life made us vulnerable to COVID-19 mortality.

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More intriguingly, and hopefully, Farrelly and others say the pandemic is a compelling reason to double down on a fascinating new domain of medical research. Its goal, rather than finding cures for individual diseases, is to treat the aging process itself.

Old age makes humans vulnerable to a range of killers, now including the novel coronavirus. Finding a way to slow down or reverse the aging process will protect people not just from traditional foes like diabetes and hypertension, but infectious diseases such as COVID-19, the thinking goes.

I think of it as 21st century medicine, as opposed to 20th century medicine, in which there were these silos of people who treat your heart, people who treat your lungs, people who treat your brain, Austad said. (Now) theyve started talking to each other.

Targeting aging, argues Farrelly, ought to be the major public health goal of the 21st century.

Nobody has run away from aging by dieting and exercising ... To change the paradigm, we need to look at pharmaceuticals

What anti-aging scientists are pursuing is not the lifestyle fixes long proven to lessen disease risk, like regular exercise and a healthy diet. Instead, theyre searching for drugs and dietary supplements that could actually tweak human biology to better withstand the ravages of time.

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The key seems to be that the animal somehow avoids the clumping together of protein on the shell-opening tissue, a factor for humans not just in muscle ailments, but neurological diseases like Parkinsons and Alzheimers, too, Austad said.

Meanwhile, experts like him stress there are already relatively cheap and safe drugs prescribed for other uses that have great potential as anti-aging agents. They include rapamycin, used now to combat organ rejection in transplant patients, and metformin, a diabetes medicine.

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Underlying the research are some cold, hard facts about human biology. Evolution, it seems, has ensured humans live healthily long enough to reproduce and look after their offspring until they become independent.

That translates into an average biological warranty period of about 70 years, the time before which the body begins to undermine itself, increasing the risk of disease and frailty, says Farrelly. So as weve learned to at least manage diseases of old-age and get people to live longer, the result is often years of illness and disability at the end of life, he said.

But thats not to say that growing old and weak in the way we expect is written in stone.

Theres no law of physics or law of the universe that says that aging has to occur, said Austad. Living organisms are almost definable by their ability to repair themselves Aging is the ultimate failure of repair. (But) that doesnt mean its not possible to intervene in the system.

Such intervention would not necessarily extend lifespans, but ideally make the later years healthier and more productive, a major advance in itself.

That would change the nature of human existence incredibly, said Austad. If you had another 10 to 20 years of healthy life to look forward to, that might influence almost everything you did when you went to school, when you had kids, how many careers you had.

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After it was discovered in the soil of Easter Island in the 1960s, Canadian researchers at Ayerst Pharmaceuticals found it had fungal-fighting properties. It eventually was approved as an anti-rejection drug. What has been learned about it since suggests its one of the very brilliant molecules that nature made, said Zhavoronkov, founder of Hong Kong-based companies Insilico and Deep Longevity.

It should be administered under a doctors supervision and tailored to individual recipients, he said, but the time is now.

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Theres no law of physics or law of the universe that says that aging has to occur

The trillions of dollars governments have spent on the fallout from COVID-19 with its disproportionate burden on the elderly drives home the point, he argues.

So how soon before a drug arrives that brings, not immortality exactly, but a longer healthspan?

Austad believes it s coming within 10 years. Zhavoronkov is also optimistic, saying the last decade has seen remarkable progress, more discoveries in aging medicine than in the entire human history.

It feels personal to Farrelly, a political-studies professor who monitors geriatric science. His mother died in the midst of the pandemic after years of battling cancer, unable to see family in the last three months of her life because of COVID protocols. But hes hopeful.

I believe it will happen in my kids lifetime, said Farrelly. They wont age like my mother did.

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The Anti Aging Medicine Market to witness livewire performance between 2020 and 2030 NeighborWebSJ – NeighborWebSJ

Longer life-expectancy is a cumulative effect of a healthy lifestyle and favorable environmental conditions. A trend of continuously increasing life expectancy has been a witness since a decade, primarily because of advances in medical sciences and treatment of chronic life-threatening diseases, availability of clean water and environment and other factors. This trend is projected to further show even more exponential growth graph owing to the anti-aging medicines, stem cell therapeutics, genetic screening and interventions, and high-tech biomedicines. American Academy of Anti-Aging Medicine claimed that anti-aging medicines can add up to 10-20 years to the life expectancy of a human. Today, a combination of calorie-restricted diet, regular exercise, and anti-aging medicines are claimed to slow the process of senescence and aging. Various medicines used against the treatment of acute or chronic diseases can be considered as anti-aging medicines, however, to define anti-aging medicine market we have considered only the drugs that are directly prescribed and used for delaying the effects of aging.

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The constantly growing demand to look young in old individuals and to remain young and youthful in young people drive the anti-aging market. The influence of aesthetics from the fashion and television industry propel the demand to retain the features and energy of younger age in old people. Additionally, the increasing number of anti-aging medicine manufacturers in the decade contribute to higher availability of the anti-aging medicine resulting in expansion of the global anti-aging medicine market. However, skeptical approach to anti-aging medicine as being an external stimulator of cell-cycles is a restraint to the expansion of anti-aging medicine market.

The global Anti-aging medicine market is segmented on basis of product type, age group, distribution channel, and region:

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The rising demand for beauty consciousness amongst people and the desire to stay young is the primary factor fueling the growth of anti-aging medicines in the market. The acclaimed benefits of the products and affordability along with regional presence compel the demand for anti-aging medicine in the global market. Hormonal replacement therapy segment in product type is expected to account maximum market share in the terms of revenue in the global anti-aging medicine market. However, antioxidant therapy segment in product type is expected to grow with the highest CAGR over the forecast years owing to the rising awareness about the plethora of benefits of antioxidants in anti-aging among the public. On the basis of the route of administration, the global anti-aging medicine market is segmented as oral, injectable and topical, out of which oral segment is expected to generate maximum revenue share over the forecast period. As per the distribution channel, the global anti-aging medicine market is segmented as hospital pharmacies, retail pharmacies, e-commerce, and drug stores. The e-commerce segment in the distribution channel is estimated to grow with the highest CAGR over the forecast time.

Regionally, the global anti-aging medicine market is segmented into five key regions viz. North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America anti-aging medicine market is projected to account for the largest market share in the terms of revenue in the global anti-aging medicine market owing to the higher healthcare expenditure and presence of numerous manufacturers. Europe is expected to hold the second largest share in the global anti-aging medicine market during the forecast period because of the growing geriatric population and higher spending on healthcare products and supplements. MEA anti-aging medicine market is expected to witness sluggish growth over the forecast time owing to the limited presence of manufacturers and lower healthcare expenditure. Asia Pacific is projected to grow with the highest CAGR over the forecast years in the global anti-aging medicine market due to higher demand from end users and regional penetration of the key players in the region.

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Some of the players operating in the global anti-aging medicine market are

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Board-Certified Dermatologist and Baylor Professor: Has the Pandemic Accelerated Aging Skin? – Newswise

While 2020 may have felt like the longest year, unfortunately, there is one aspect of the pandemic that may have been accelerated aging skin.

According to board-certified dermatologist Rajani Katta, MD, FAAD, clinical assistant professor at the Baylor College of Medicine, a combination of factors brought on by the pandemic are contributing to growing complaints of accelerated skin aging.

Some of this has to do with perception and what I call Zoom face. Between the poor lighting, harsh shadows and strange angles in which were seeing ourselves on camera, its the equivalent of looking at our face for hours in an unflattering mirror, said Dr. Katta. In addition to more video calls, the pandemic has ushered in many sleepless nights and increased stress levels, which we know can contribute to premature skin aging.

Dr. Katta is also seeing more patients who are experimenting with at-home treatments like peels and masks that can cause redness, irritation and flaking skin, which can make your skin appear older. Some patients who are experiencing skin irritation from wearing a face mask have had to stop using effective anti-aging products altogether during the pandemic. Finally, lifestyle changes that include less exercise and more unhealthy eating have contributed to accelerated skin aging.

Dr. Katta is available to discuss additional insights on how the pandemic is impacting peoples skin and offers these tips to her patients.

Five tips for combating aging skin during the pandemic:

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More Information

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Board-Certified Dermatologist and Baylor Professor: Has the Pandemic Accelerated Aging Skin? - Newswise

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