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Advanced Age Management Offer Testosterone Replacement Therapy – The News Front

Advanced Age Management offers Testosterone Replacement Therapy. This mens clinic is located near Cleveland, OH, and it gives men the perfect solution if they are feeling sluggish, low energy, gaining weight, or they have a decreased sex drive. Advanced Age Management says if youre over the age of 35, you could have low testosterone, and this is normal as you get older, but you will start to notice issues more and more as you age.

This mens clinic in Cleveland, OH, says it is due to a condition called Hypergonadism, yet, they want to reassure individuals who may be concerned and worried that their testosterone production level is low, that is why they are now offering testosterone replacement therapy in their clinic. If you are suffering from one of the issues mentioned above, definitely consider scheduling an appointment with your doctor and get your testosterone levels checked. Contact Advanced Age Management, and they will advise you on your next step and get you in for a free testosterone assessment.

At Advanced Age Management, their goal is to help men build up their testosterone levels by testing testosterone levels and creating a treatment plan to get the testosterone levels back to an appropriate level so that each individual does not have to suffer anymore and can carry on with their life. This is all done through the testosterone replacement therapy at their mens clinic.

It would be best if you got in touch with Dr. John Kocka at Advanced Age Management, a low testosterone expert who carries out a series of assessments and testosterone replacement therapy for men and women in and around Cleveland Ohio. According to Advanced Age Management, the cost of the testosterone replacement therapy varies from each patient to the next, as each person will require a different treatment plan. You can, however, schedule a free consultation and also review your financial information with Dr. John Kocka once you get in touch.

Advanced Age Management emphasizes that the therapy offered to men is only for those with testosterone deficiencies, which is why this mens clinic is the best to consult with if you have found out that you have low testosterone. If needed, Dr.Kocka can offer you a same-day consultation.

If you have been given the go-ahead for testosterone replacement therapy, Advanced Age Management assures you that there are many benefits of testosterone treatment. There is evidence to suggest the therapy can improve your cardiovascular health by removing cholesterol from your arteries, a common issue that many men suffer with as they get older.

The mens clinic in Cleveland, OH, assists men for other hormone treatments as well, such as DHEA, cortisol, thyroid, natural growth hormone, insulin, and more.

Contact Advanced Age Management today at (330) 439-6591 and schedule your free consultation with one of their low testosterone doctors. This mens clinic is offering you the chance to increase your testosterone levels and, in turn, improve your health and overall well-being. At Advanced Age Management, the doctors use injection therapy for men who need more testosterone production. You can read more about low testosterone and the testosterone replacement therapy on their website at


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Advanced Age Management Offer Testosterone Replacement Therapy - The News Front

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Global Hormone Replacement Therapy (HRT) Tablets Market Trends, Research, Analysis & Forecast 2026 Major Growth By Novo Nordisk A/S, Sanofi,…

The hormone replacement therapy (HRT) tablets market study consists of the key factors of strategic trends of the market including R&D, new product launching, agreements, collaborations, partnerships, joint ventures, and local size of the leading competition performing within the market on a worldwide and regional scale. This industry analysis report consists of the exactly studied and weighed statistics of the important thing enterprise players and their scope within the market via the method of numerous analytical gears. The hormone replacement therapy (HRT) tablets market report will surely offer strategic and tactical support to clients for making well-informed business decisions.

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Few of the major competitors currently working in the global hormone replacement therapy (HRT) tablets market areALLERGAN, Novo Nordisk A/S, Sanofi, Abbott, TherapeuticsMD, Inc., Mithra Pharmaceuticals among others.

Key Development in the Market:

Competitive Analysis

Global hormone replacement therapy (HRT) tablets market is highly fragmented and the major players have used various strategies such as new product launches, expansions, agreements, joint ventures, partnerships, acquisitions, and others to increase their footprints in this market. The report includes market shares of hormone replacement therapy (HRT) tablets market for global, Europe, North America, Asia-Pacific, South America and Middle East & Africa.

Table of Contents

1. Introduction2. Market Segmentation3. Market Overview4. Executive Summary5. Premium Insights6. Global, By Component7. Product Type8. Delivery9. Industry Type10. Geography

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Segmentation: Global Hormone Replacement Therapy (HRT) Tablets Market

By Type of Disease

(Menopause, Hypothyroidism, Male Hypogonadism, Growth Hormone Deficiency, Others),


(Estrogen Replacement Therapy, Human Growth Hormone (HGH) Replacement Therapy, Thyroid Replacement Therapy, Testosterone Replacement Therapy, Others),

End User

(Hospitals, Clinics, Ambulatory Surgery Centers, Others),

Distribution Channel

(Direct, Retail),


(North America, Europe, Asia-Pacific, South America, Middle East and Africa)

By Type of Disease

By Treatment Type

By End-User

By Distribution Channel

By Geography

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Global Hormone Replacement Therapy (HRT) Tablets Market Trends, Research, Analysis & Forecast 2026 Major Growth By Novo Nordisk A/S, Sanofi,...

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Females Live Longer Than MalesAmong Humans and Other Mammals, Too –

Women live longer than men by an average of six to eight years, according to the World Health Organization. This intriguing trend is seen in nearly every country around the world, suggesting that it may be driven by profound biological differences between the sexes. And longevity may not be limited to human females; according to a sweeping new study in the Proceedings of the National Academy of Sciences, a range of female mammals live longer than their male counterparts, too.

Scientists have long assumed this to be true, but according to the study authors, the assumption was based on a small number of case studies on wild mammals, or records of mammals housed in captivity, where lifespan and aging patterns are often not representative of conspecifics in the wild. For the new report, the researchers compiled and analyzed demographic data from different types of studies, including mortality estimates that had been obtained from long-term monitoring of wild populations, and mortality rates obtained from dead animals collected in the field. In total, the teams analysis covered 134 populations and 101 species, including lions, orcas, reindeer, and squirrels.

Among 60 percent of the populations studied, females lived longer than males. On average, their lifespans were 18.6 percent longer, which is considerably higher than the advantage for female humans, who live on average 7.8 percent longer than their male counterparts.

But why do such discrepancies exist between the sexes? Scientists have long sought to answer this question as it pertains to humans, and complex behavioral differences likely come into play. Men, for instance, are more likely to smoke, drink excessively and be overweight, Perminder Sachdev, a professor of neuropsychiatry at the University of New South Wales in Australia who has studied human longevity, told Times Markham Heid last year. They are also less likely to seek medical help and to adhere to medical treatments.

Biological factors may also drive the survival gap. Testosterone, for instance, increases levels of low-density lipoprotein cholesterol in men, putting them at greater risk of hypertension, stroke and heart disease.

Womens biology, on the other hand, may give them a boost. One theory posits that having two copies of the same sex chromosome confers protective benefits that govern longevity; women have two copies of the X chromosome, while men have X and Y chromosomes. Earlier this month, a study in Biology Letters gave credence to this hypothesis when it found a link between sex chromosomes and lifespan across more than 200 species. Female mammals, which have two of the same chromosomes, tended to live longer than males. The dual-chromosome trend applied to species that don't have X or Y chromosomes, too, and to species that in which males have two of the same chromosomes. For example, male birds, which have two Z chromosomes, have the survival advantage over females, which have one Z and one W chromosome.

The authors of the new study note that male mammals also devote substantial resources toward the growth and maintenance of secondary sexual traits, like larger body size or antlers. In certain environmental circumstances, these traits might come at a cost. When looking at bighorn sheep, for instance, the researchers found virtually no difference in lifespan between males and females in ranges where resources were consistently available. But in one location where winters are particularly harsh, there were significant sex differences in lifespan.

Male bighorn sheep use lots of resources towards sexual competition, towards the growth of a large body mass, Jean-Francois Lematre, first author of the new study, tells Matt McGrath of the BBC. [T]hey might be more sensitive to environmental conditions.

Both genetic variations and environmental conditions, in other words, likely play a role in sex differences in lifespan. Untangling these intertwined factors wont be easy, the study authors acknowledgebut further research, they write, will undoubtedly provide innovative insights into the evolutionary roots and physiology underlying aging in both sexes.

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Female Mammals Live Longer Than Their Human Counterparts – Science Times

(Photo : pexels)White coated Lamb

A person's life expectancy is an important indicator of the health status based on the average number of years a person may be expected to live at a given age in consideration with the current mortality rates.

Study shows that females live longer than males. According to the latest figures released by the CDC, the average American man lives up to age 76 while the average woman in America lives up to 81 years. Note that the woman's extra years tend to be healthy ones.

American men can look forward to 67 healthy years, while American women enjoy 70 years living a healthy life, according to the World Health Organization's HALE index, which computes how long a man or a woman can expect to live without having a major disease or injury.

This supports the results of a recent study on mammals that shows females live substantially longer than males. On average, females live up to 18.6% longer than males from the same species.

The study conducted by the researchers from the University of Southern Denmark and University Lyon 1 in collaboration with several international teams, came up with the results that although women live longer than men, they are still outlived by their female mammal animal counterparts.

A wild mammal lives 18.6% longer than males of the same kind, while the difference between a man and woman's life expectancy is only 7.8%. Their findings were published in the Proceedings of the National Academy of Sciences of the United States (PNAS).

Associate professor and an expert in biostatistics at Interdisciplinary Centre on Population Dynamics, University of Southern Denmark, Fernando Colchero, identified animals such as the lion, killer whale, brushtail possum, moose, greater kudu, and sheep as the best examples of non-human mammals that shows great differences on life expectancy.

Over 130 wild mammal populations were analyzed by the researchers and they were able to estimate the average longevity and rate of increase in the risk of dying because of the age for both sexes of the animal. Their analyses led to an unexpected result that a vast majority of cases exceeds the difference observed between non-human mammals to the human populations.

Experts say that the male-female lifespan gap is not a new phenomenon and it is not only restricted to Americans. It is true to all societies, and even true for the great apes, according to a professor of neuropsychiatry at the University of New South Wales, Dr. Perminder Sachdev who studied human longevity.

Sachdev explained that the reason why women tend to live longer than men is because of biology and behavior.

Unlike women, men are more likely to indulge in a sedentary lifestyle like smoking, excessive drinking, and be overweight. Additionally, men are also less likely to seek medical help early once they are diagnosed with a disease, and are also more likely to be non-adherent to treatment.

To top it all off, men are more likely to engage in risky activities that are life-threatening such as brawls or gunfights making them more susceptible to dying earlier than women.

Another explanation could also be because of a man's biology. Males produce more androgens, a male hormone that modulates immune performance. When it is present at high levels, androgens can impair some of the aspects of the immune defense that results in men more likely to be infected with diseases.

Female Mammals Live Longer Than Their Human Counterparts - Science Times

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COVID-19 State of the Industry Town Hall with J. Craig Venter – SynBioBeta

In 2000, synthetic biology visionary J. Craig Venter completed the first draft of the human genome. Ten years later, his team created the first synthetic cell. Craig will join SynBioBeta founder John Cumbers for a conversation about the state of the synthetic biology industry. In light of SARS-CoV-2, well also ask what the coronavirus pandemic means to innovation, our community, and our relationship with society. Well discuss:

Tuesday, March 31, 2020, 8 am Pacific

J. Craig Venter is known for leading the first draft sequence of the human genome. He later assembled the first team to transfect a cell with a synthetic chromosome. Venter founded Celera Genomics, The Institute for Genomic Research (TIGR) and the J. Craig Venter Institute (JCVI), where he currently serves as CEO. He was the co-founder of Human Longevity Inc. and Synthetic Genomics. He was listed on Time magazines 2007 and 2008 Time 100 list of the most influential people in the world.

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Precision Medicine Software Market Worth $2.8 billion by 2027- Exclusive Report by Meticulous Research – Benzinga

London, March 26, 2020 (GLOBE NEWSWIRE) -- According to a new market research report "Precision Medicine Software Marketby Delivery Mode (On-premise, Cloud-based), Application (Oncology, Pharmacogenomics, CNS), End User (Healthcare Providers, Research, Academia, Pharma, Biotech) Global Forecast to 2027", published by Meticulous Research, the precision medicine software market is expected to grow at a CAGR of 11.8% from 2019 to reach $2.8 billion by 2027.

Since many years, various medicinal approaches have been used for providing accurate treatment to the patients. Precision medicine is also an emerging approach to patient care through which physicians choose a treatment method based on the patient's genetic makeup (also taking into consideration genetic changes resulting from disease) and lifestyle habits. Precision medicine has the ability to remove the need for guesswork, variable diagnostic ability, and treatment strategies based on generalized demographics. Moreover, treatment using precision medicine enables a more holistic view of an individual patient. Application of precision medicine for clinical workflows help to facilitate more predictive and preventive care by bringing targeted therapies. This helps healthcare providers to further improve the standard of care by combining the ability to quickly make a treatment.

The precision medicine software market study presents historical market data in terms of value (2017, and 2018), current data (2019), and forecasts for 2027 - by delivery mode, application, and end user. The study also evaluates industry competitors and analyzes the market at regional and country level.

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On the basis of delivery mode, the on-premise segment accounted for the largest share of the overall precision medicine software market in 2019. The large share of this segment is mainly attributed to broad range of advantages associated with the use of on-premise delivery mode, such as high security of data, low risk of data breaches, and full command over software upgrades & data storage. In addition, higher adoption among end-users and flexibility with connection bandwidth further contribute to the largest share of this segment. However, the web & cloud-based delivery mode segment is expected to grow at the highest CAGR during the forecast period, owing to its benefits, such as on-demand self-serving, no maintenance cost, low storage & upfront cost, and excessive storage flexibility. In addition, the factors such as greater security in private clouds and automated updating features of web and cloud solutions are further expected to support the rapid growth of this segment.

Based on application, the oncology segment accounted for the largest share of the overall precision medicine software market in 2019. The factors such as growing prevalence of cancer, shift towards personalized treatment, rising funding in cancer research, applications of precision medicine in oncology research, and increased investments by government organizations in precision medicine and related software industry contributed to the largest share of the oncology segment. However, the pharmacogenomics segment is expected to witness rapid growth during the forecast period. The factors such as increasing incidence of adverse drug reaction, growing focus on genomic-based study, shift from one-size-fits-all approach to personalized approach, and rising pressure on pharmaceutical companies to develop new drugs promote the fastest growth of this segment.

Based on end user, the healthcare providers segment commanded the largest share of the overall precision medicine software market in 2019. The large share of this segment is primarily attributed to the rising number of tertiary/specialty care hospitals, rising incidence of chronic diseases, growing healthcare infrastructure, increasing demand for quality healthcare, and shift towards personalized/precision medicine. In addition, rising pressure to curtail soaring healthcare costs, technological advancements, and focus towards genomic-based treatment further supports the growth of the precision medicine software market for healthcare providers across the globe. However, the pharmaceutical & biotechnological companies segment is expected to witness rapid growth during the forecast period. The factors such as increasing R&D activities related to precision medicine, increasing collaboration between pharma & biotech companies and software vendors, shift from conventional "one-size-fits-all-type" treatment to precision treatment, and rising R&D costs are the major factors driving rapid growth of this segment.

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Geographically, North America dominated the overall precision medicine software market in 2019, followed by Europe and Asia Pacific. The factors such as well-established healthcare system in the region, rising adoption of technologically advanced products for cancer diagnosis & treatment, growing HCIT investment, government initiatives supporting developments in precision medicine, growing availability of research funding, and higher accessibility to precision medicine software are responsible for the largest share of North America in the precision medicine software market. However, Asia Pacific region is expected to grow at the fastest CAGR during the forecast period. The factors driving the growth of this region include growing shift in treatment from one-size-fits-all medicines to precision medicine, significant strides in genomics research & technology, increased spending on healthcare, rising funds for research activities, and growing focus of international players to expand their presence in this region.

The report also includes extensive assessment of the product portfolio, geographic analysis, and key strategic developments adopted by the leading market participants in the industry over the past 4 years (20162019). The precision medicine software market has witnessed number of new software launches; approvals; collaborations, partnerships & collaborations; expansions; and acquisitions in recent years. For instance, in September 2019, Fabric Genomics, Inc (U.S.) entered into an agreement with XIFIN, Inc. (U.S.) to enable end-to-end, rapid, and highly scalable NGS testing. In August 2019, Syapse, Inc. (U.S.) entered into an agreement with the U.S. Food and Drug Administration (FDA) Oncology Center of Excellence (OCE) to work with stakeholders across the FDA to address regulatory questions about testing and treatment patterns, dosing and safety, and outcomes in oncology with special focus on precision medicine.

The key players operating in the global precision medicine software market are Syapse, Inc. (U.S.), Fabric Genomics, Inc. (U.S.), SOPHiA GENETICS SA (Switzerland), Human Longevity, Inc. (U.S.), Sunquest Information Systems Inc. (U.S.), LifeOmic Health, LLC (U.S.), Translational Software Inc. (U.S.), N-of-One (U.S.), Gene42 Inc. (Canada), PierianDx (U.S.), Foundation Medicine, Inc. (U.S.), and 2bPrecise (U.S.), among others.

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Scope of the Report:

Precision Medicine SoftwareMarket by Delivery Mode

Precision Medicine Software Market by Application

Precision Medicine Software Market by End User

Precision Medicine Software Market by Geography

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About Meticulous Research

The name of our company defines our services, strengths, and values. Since the inception, we have only thrived to research, analyze and present the critical market data with great attention to details.

Meticulous Research was founded in 2010 and incorporated as Meticulous Market Research Pvt. Ltd. in 2013 as a private limited company under the Companies Act, 1956. Since its incorporation, with the help of its unique research methodologies, the company has become the leading provider of premium market intelligence in North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa regions.

With the meticulous primary and secondary research techniques, we have built strong capabilities in data collection, interpretation, and analysis of data including qualitative and quantitative research with the finest team of analysts. We design our meticulously analyzed intelligent and value-driven syndicate market research reports, custom studies, quick turnaround research, and consulting solutions to address business challenges of sustainable growth.

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Precision Medicine Software Market Worth $2.8 billion by 2027- Exclusive Report by Meticulous Research - Benzinga

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Longevity worldwide is the scary part of Covid-19 – Indian NewsLink

Adam Kleczkowski and Rowland Raymond KaoGlasgow and Edinburg, Scotland, March 26, 2020

The COVID-19 pandemic has already caused several thousand deaths, widespread health problems, massive anxiety and economic losses.

Most people are concerned with what happens day by day as we wait for control measures to work.

But we should also be concerned about whether or not we will be living with the virus for a long time. Will we be able to eradicate COVID-19, as we did with Sars? Or will we need to learn to live with it like we do with the common cold? We have been experiencing epidemics and pandemics for centuries, so there are lessons we can draw from these examples.

The virus in the long run

To understand what happens to the virus in the long term, we need to look at how large epidemics work, starting with patient zero.

If there is significant human-to-human transmission, the virus begins to spread, causing a fast increase in the number of cases (illustrated in the figure below). At the same time, those who overcome the disease and develop resistance are henceforth immune, at least for a while.

The people who are newly infected will increasingly have contact with these immune people, rather than with those who have not yet had the disease. This process effectively protects the susceptible population and causes the initial fast growth to slow and eventually stop.

The level of immunity

The level of herd immunity needed to stop the spread depends on both the number of contacts an average person has and how infectious the disease is. If highly contagious, this can be as much as 95%. This protection can be achieved by a combination of reducing infectiousness through immunity, either natural or acquired, or vaccination, or by reducing transmission.

Quarantine and mass restrictions on travel have proved effective, as shown in China, where the number of COVID-19 infections outside of Hubei province, where it started, have been few.

What happens next depends on the disease characteristics and human actions.

The 1918 flu virus did not persist after the early 1920s probably because enough people became immune to it. However, many pathogens are difficult to eradicate globally, although local success is possible. For example, foot-and-mouth disease, which affects sheep and livestock, survives in many countries.

The outbreak in the UK in 2001 was reduced to local islands of infection by an animal movement ban and then eradicated by massive culling.

But it took a long time and high costs to finally bring it to an end (figure below). Like many countries, the UK now has strict rules of animal imports, aimed at stopping the disease from arriving again.

Vaccine for coronavirus

It is possible that we will eradicate COVID-19 in selected countries or regions, but not necessarily worldwide. Although there are hopes that a vaccine will be successful within the next year, this is not certain. If it happens, very stringent travel checks may need to be imposed for at least a substantial time such a restriction, added on to concerns of the impact of air travel on climate change, may mean that the tourism industry may never recover.

Some diseases prove impossible to eradicate even in the long term and will persist following the first outbreak (figure below).

Diseases originating in Europe and Africa were brought to North America for the first time in the late 1400s and early 1500s. Encountering a population with little immunity, smallpox and other diseases spread rapidly causing the collapse of indigenous communities.

Subsequent outbreaks were lower, but smallpox and measles persisted until the 20th century.

Seasonal ailments

In temperate climates, seasonal influenza spreads rapidly through winter but mostly dies out in summer, only to come back the following year. In between outbreaks, the flu virus survives in Asia from where it emerges every year.

Large measles epidemics, before vaccines were available, occurred every two or three years, interspersed with small outbreaks (figure below).

The recurring pattern was caused by people being born all the time without vaccine protection.

Next winter, when children went back to school, there were enough susceptible ones to create a large outbreak. With mass vaccination of children, this influx was slowed down enough to create herd immunity and almost eradicate the disease.

However, measles is returning because vaccination levels are falling below the herd-immunity threshold.

The future of Covid-19

So what is the future of COVID-2019? While we cannot be sure, mathematical models help us explore scenarios and identify potential outcomes, building on our experience of past outbreaks.

The governments are hoping that a combination of social distancing, border closures, isolation of cases, testing and increasing immunity in the population will slow down the spread of the coronavirus and will hopefully open up successful eradication strategies.

Yet, past experiences suggest that we may need to learn to live with the coronavirus for years to come.

Adam Kleczkowski is Professor of Mathematics and Statistics. University of Strathclyde based in Glasgow, Scotland; Rowland Raymond Kao is Sir Timothy OShea Professor of Veterinary Epidemiology and Data Science at the University of Edinburgh, Scotland. The above article and charts have been published under Creative Commons Licence.

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Longevity worldwide is the scary part of Covid-19 - Indian NewsLink

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What Does Our Body Temperature Say About Our Health? – The New York Times

Such a substantial change in average temperature over a fairly short period of history could have other, unforeseeable impacts. Parsonnet points out that there are more microbial organisms in us than there are human cells, which creates a complex ecosystem. And like a human-size version of climate change, were seeing probably a change in our ecosystem thats associated with this drop in temperature. Yet were only beginning to understand all the ways temperature influences that ecosystem to help determine how we function.

Our body temperature is controlled by the hypothalamus, which acts as a thermostat, keeping the temperature of vital organs fairly constant. (Its this core temperature that a thermometer approximates.) Temperature sensors in nerve endings, which produce the sensation of being hot or cold, prompt the hypothalamus to initiate adjustments like shivering to warm up or sweating to cool down. At any given time, your skin might be 10 degrees cooler or warmer than your core. And that difference and thus how much energy the body has to expend to keep the core stable seems to affect how the immune system functions. For instance, in 2013 Elizabeth Repasky of the Roswell Park Comprehensive Cancer Center and co-authors reported in P.N.A.S. that raising the room temperature improved the ability of laboratory mice to fight off cancer after they got it. Repasky and others are also experimenting with heating tumor cells to kill them or make them more susceptible to chemotherapy. Already, certain abdominal cancers are treated with hot chemotherapy, in which the drug is heated to 103 degrees, which has been shown to increase how much of it is absorbed by cancer cells. Separately, the heat from a fever may help fight infection, because, as Mark Dewhirst, an emeritus professor of radiation oncology at the Duke University School of Medicine, puts it, a lot of bacteria and other pathogens dont fare well at elevated temperatures.

Scientists struggle, though, to explain how a cooler average body temperature has been associated with longevity. A lower metabolic rate, and thus a lower temperature, has been linked to a longer life span in experimental settings with reduced calorie intake, when the body slows to conserve energy. But Bruno Conti, a professor of molecular medicine at the Scripps Research Institute, and colleagues have also found that mice genetically engineered to have a body temperature a half-degree lower than average lived longer than ordinary mice, even if they ate as much as they wanted. What other effects this has on an organism is unknown. For instance, he says, a brain at a lower temperature might not function as well.

At the same time, other bodily systems might benefit from being cooler. H. Craig Heller, a biology professor at Stanford, and colleagues have shown that muscle fatigue is caused by heat, which they believe triggers a temperature-sensitive enzyme that acts as a safety valve, stopping the production of chemicals that power muscle contractions in order to prevent the tissue from burning up. When Heller cools muscle during physical activity using special gloves that chill blood as it moves through the hands, the muscle just keeps on going, he says. Ive had freshmen doing more than 800 push-ups.

What Does Our Body Temperature Say About Our Health? - The New York Times

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How healthtech startup Bione aims to use genetic testing in the fight against coronavirus – YourStory

Ever since the Human Genome Project began in the late 1980s, genetics and DNA have become topics of mass interest. The book Genome: The Autobiography of a Species in 23 chapters states that the genome is a book that wrote itself, continually adding, deleting, and amending for over four billion years.

For Dr Surendra Chikara, who has been working in the field for over 20 years now, the idea of founding Bione, a healthcare startup, was a no-brainer.

Monitoring the present coronavirus outbreak scenario in the country, we have included new parameters to our Longevity Plus kit. The new updated kit provides information about the susceptibility of a person to viruses like coronavirus, SARS-like viruses, HIV, Hepatitis C virus, etc. This could be based on an individuals genetic makeup or the patterns of living, Surendra says.

Dr Surendra, Founder of Bione

Surendra says a recent addition to the Bione Genetic test can check an individuals susceptibility to coronavirus. He adds that the platforms microbiome test, combined with its predictive analytics tools and artificial intelligence, can provide tailored recommendations to individuals to strengthen their microbiome and improve their immunity.

A research paper titled 'Evidence of gastrointestinal infection of SARS-CoV-2 revealed that 23.29 percent patients infected with SARS CoV-2 showed positive results in stool after showing negative in respiratory samples. Hence, the gut microbiome test is the only way to know when a virus is no longer in your system, Surendra says.

Surendra started his career with recombinant DNA technology and worked with Dr Gita Sharma, who had created the first r-DNA vaccine for Hepatitis-B in India.

My journey in genomics started under her support and guidance. It was the time when human genome sequencing and next-generation sequencing were starting to gain importance. We were in discussions to bring D2C technology to India, but the Indian healthcare market was not ready for direct-to-consumer genetic testing," Surendra says.

This is a huge problem that all my networks were aware of. We all know that the future of the global pharmaceutical industry lies in developing precision medicines tailored for individuals based on their genes, and clinical risk for developing a disease. Indian genetic data is highly diverse and a number of breakthroughs can happen. At Bione, we are doing our part to be part of this bigger picture of making India disease-free, Surendra says.

The different types of kits depend on the number of tests covered, and include Longevity kit, Longevity Plus Kit, and MyMicrobiome kit. The Longevity Plus kit covers over 415 parameters, including health, personalised medicine, fitness, and wellness.

The team claims that it also covers a parameter that determines specific gene variants that may contribute to enhance resistance to viruses like coronavirus, HIV, Hepatitis C, and many others.

The MyMicrobiome kit identifies and quantifies the microbiome in the gut, based on which a personalised diet is recommended.

Surendra says scientific research has shown that the gut microbiome plays an important role in the function and maintenance of our immune system. In ideal conditions, this microbiome-immune system alliance allows the initiation of protective responses against germs.

The platform also offers sample collection, with samples collected from an individuals homes. A pick-up is arranged as per your convenience by Bione. The DNA sequencing is done in a well-equipped lab by expert scientists, after which a detailed report is prepared.

Bione gXplore is a user-friendly, informative, and interactive app-based platform. On it, you can go through your report and easily understand the results of DNA analysis.

Slots with genetic or food and nutrition counsellors are provided as a free-of-cost service. The expert team of counsellors guides you to proactively plan your and your familys health and lifestyle choices.

The Bione team consists of experts from global institutions and scientists domains of genomics, genetics, bio-IT, genome informatics, quality assurance, sales, marketing, genetic/nutrition/fitness counselling. The startup has a total team size of 39 people.

The startup also runs a lab with scientists, bioinformaticians, and genetic counsellors. The team is applying for ISO 9001:2015, followed by CAP and CLIA accreditation to follow global standards.

Bione is projecting to test 20,000 to 30,000 samples in the first year of operations. Tests are priced between Rs 5,000 to Rs 20,000, with the option of paying in EMIs. Customers can choose the package based on their needs.

The startup has raised angel funding from a clutch of undisclosed investors. Gourish Singla, the Founder of blockchain startup Project Shivom has invested in Bione.

Currently, startups like The Gene Box and Hyderabad-based MapMyGenome work on providing preventive solutions based on an individuals genetic makeup.

He says the startup's high tech lab is using advanced technologies, including whole genome sequencing, while the competition is still working with array technology with limited markers.

(Edited by Kanishk Singh)

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His Nickname is Dr. Disaster and at Some Point You May Need Him – Yahoo Finance

NEW YORK, NY / ACCESSWIRE / March 26, 2020 / "Crises are in the eye of the beholder" says Dr. Joshua Klapow, a clinical psychologist . And that's in part how he got the nickname Dr. Disaster.

Crises come in all shapes sizes and degree of impact. For some it's the down turn of their company in a struggling economy, for others it's a relationship on the rocks. Sometimes crises affect many hundreds or thousands, natural disasters, mass shootings, terrorist attacks. Sometimes they can even be global like a pandemic. In any of these scenarios the psychological and emotional toll on individuals can be devastating. Communities, cities, states, nations can suffer from global distress, a sense of helplessness, and difficulty making decisions and choices that can help them carry on. In any crisis what people do or don't do and how they do or don't do it determines in some cases whether they survive or not, and in all cases whether they thrive or not.

So where can we turn? Where should we turn? Dr. Josh believes that at the heart of every crisis is human distress that needs guidance to see it through. And for years, Dr. Josh has served that role to individuals, companies, cities, states and even nations. And that's how he came by the nickname Dr. Disaster. From his presence across media outlets when "disaster strikes".

As he says "Unfortunately I have taken on this nickname. When bad things happen you will often see me on television, hear from me on radio or read my words in print. The good news is that when bad things happen to you, your company, your city or state, you can count on me to be there with the tools, and the experience to help people tap into their psychological resiliency and work through a crisis. So I guess Dr. Disaster isn't that bad after all".

Dr. Josh has been working for decades with people in a variety of crisis situations: A CEO in the middle of a contested divorce trying to compartmentalize the stress divorce while maintaining the functioning of a multimillion-dollar business. An elite athlete who has just seen their season end due to a catastrophic injury and now must face the transition to a next life chapter. A start up company that fell on a tough economy and now is faced with massive downsizing while looking after their employees well being. A multibillion-dollar company that is struggling with the retention of high performing individuals who are leaving in droves because of a punitive management culture. Or maybe it's a tornado, or hurricane or earthquake that has decimated a city or state. Or a global pandemic that has struck fear in the hearts of frankly the world. Dr. Josh is usually there. It may be for a one on one series of consultations out of the media's eye. It may be as an advisor helping leadership making tough decisions about layoffs. You may see him on television; hear him on the radio, read his quotes in print as he tries to get the messages out to the masses.

Dr. Josh is there to help people navigate . He explains:

"In times of crises, big or small, at the individual level or global, as a general rule we, humans experience levels of distress that impact every aspect of our functioning. Crises change the way we think, the way we process information, the way we `function. Having the right tools to reduce our anxiety, focus our concentration, regulate our autonomic nervous system is critical. Even then, when people are undergoing prolonged stressful situations, they need someone who can point out the cognitive errors, the irrational beliefs, and the self-defeating actions that come with being under immense pressure. I see it at the individual level but I also see it at the group and population level. A distressed management team makes human resource decisions that often are focused on relieving their own distress but not focused on maximizing the productivity or longevity of their employees. A distressed community engages in a series of actions typically aimed at reducing individual anxiety but not looking at the interconnectedness of their interactions. Crisis does bring out the best in some people but it also brings our weakest psychological characteristics to the forefront. My job is to help guide people through the crisis of their lives. "

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While having significant life and/or business experience is a great backdrop to helping people, it doesn't formally prepare a person to manage the intense emotions, the erratic decisions, the fear, anxiety and at times irrational behavior that happens when people are experiencing a life crisis. Understanding how stress, anxiety, perceived danger, escape preferences, cognitive biases and psychophysiological deregulation impact every aspect of an individuals life is critical to help them navigate crisis situations.. There are many untrained or poorly trained individuals in the marketplace providing high-priced services to people and organizations in very high profile, high scrutiny, and high-pressured positions. Watching this happen in everyone from start-up CEOs to executives in publicly traded organizations to professional athletes and entertainers to entire communities is what motivated Dr. Josh Klapow to step in.

Joshua Klapow, Ph.D. is a licensed clinical psychologist. He has a specialization in behavioral medicine and disaster mental health. He trained at UCLA and UC San Diego and spent nearly 20 years researching the role of human behavior in health, well being and the impact of disaster and crisis on human functioning as an Associate Professor in the School of Public Health at the University of Alabama at Birmingham. He has taught hundreds of graduate students and professionals the principles of psychological first aid, disaster communication and psychosocial crisis managing. He has served as a behavioral science consultant for individuals and organizations across the country as well as the World Health Organization. He has spent his entire career trying to help people thrive in situations where there are significant challenges to their physical and mental health and overall well being.

"My clinical training was specifically focused on helping people change their lives during times of challenge, strife and crisis. It was also designed to help people understand how situations and environmental settings either helped people to thrive or served as a barrier. My training was designed to help people navigate the life changes in front of them and to help people design businesses and systems of care that were much more person centered." Dr. Josh says.

Dr. Josh's traditional research and clinical work have been supplemented by a collaboration with media outlets to provide the public with the psychological first aid tools during times of crisis. From 9/11 to the variety of mass shootings, to SARS, to tsunamis, tornadoes, hurricanes, the financial crisis of 2008, plane crashes, Ebola, and COVID-19. His passion to get the message out to help people navigate fear anxiety, distress, and frustration have resulted in products such as "The Preparedness Minute", A CDC funded series of videos that have been disseminated to public health organizations and first responders across the country help people prepare and cope with national disasters. He has been called on by media outlets across the country after natural disasters, mass shootings, and disease outbreaks to help address the social and psychological impact these events have on people. From multiple appearances on The Weather Channel, to the BBC, NBC Weekend News and local affiliates across the country. To digital outlets ranging from the HuffPost, Buzzfeed, Elite Daily, Men's Health,, US News and World Report and more. Dr. Josh has been a media partner and a psychological first aid expert for nearly two decades.

He has also worked extremely closely with the business community to address the human resource impact of difficult and life changing scenarios. He has consulted on continuity planning, employee engagement, crisis communication, executive impairment, leadership transition, and psychological first aid for organizations ranging from startups to multibillion-dollar public companies. His unique expertise as a public health academician and a clinical psychologist allows him to shift from focus on the individual to groups and populations as is needed. Sophisticated technology and a deep understanding of psychology and behavioral science.

This blend of expertise in behavioral science, disaster preparedness, crisis communication and business along with his presence in the national media has positioned Dr. Josh as a sought after resource for companies and individuals across the US helping them leverage psychology and behavioral science in crisis situations. He is called on to help people survive and thrive when high levels of pressure and stress are present. He has become a public and private "go to" for those who need his input in any crisis situation or capacity.

"I know that crises will vary greatly in terms of how many people are impacted. I also know that in crisis situations there is a need for guidance that is not always delivered in a traditional "mental health" format. People need messages that are being delivered via the media, companies need guidance to make the best decisions possible for their employees, individuals need to know there is someone on the other end of a call, video conference, or text that can offer psychological tools and resources immediately to help make critical decisions. I am not a physician or an economist. My role is to know as much as is possible about how to navigate the psychological, cognitive, emotional and behavioral challenges that arise before, during and after a crisis situation. My role is to be there to make sure that you as an individual, a company or a community or nation have the right strategies to work with the impact of humans in a state of distress.

I serve as a trusted "psychological correspondent" for media outlets nationally and internationally and I work with businesses and individuals to help them bring behavioral science and psychology to the forefront of their organizations and their personal lives in the context of crises and disasters. I am here to consult and coach, to develop and support. I am here when you need an individual who can help you or your company thrive in times of crisis, change, decision making or growth. I deeply understand human behavior and I have lived the real-life experiences. Look, in my opinion it comes down to this, if you need to understand how thoughts, emotions and behaviors impact your life during some of the most critical situations and times. If you need to understand that in the context of your company, or the life of others around you, it is important that you get it right, you have to go with someone who has training and experience. Be careful, because intuition, and experience with life strife is not what you want if you need someone to help you get it right. A high level of specific training and experience is critical, because your life is critical. I've worked my whole career to prepare me to help. And I'm here to help." Dr. Josh says.

For Dr. Josh, mindset is critical because you must be willing to look at a crisis situation that may have everyone around you deregulated, distressed and convinced there are no options or their options are the only options. Being able to sit in periods of crisis and guide people through he array of emotions and actions without getting pulled down in is a skill that has to be honed and refined if you are to be at the forefront of crisis management. You have to trust your training and trust that in the middle of chaos you can hold steady as a voice of reason.

"My advice for those who are trying to help in crisis and disaster situations is to make sure you check yourself first. Do you have the tools to be strong, to know when you are exceeding your bandwidth, to join with individuals, organizational, communities while keeping yourself psychological strong. If you haven't had this kind of training you run the risk of becoming a psychological liability versus as n asset. Dr. Josh advises.

Dr. Josh is admant about pushing the message that psychological well being is a science, with specific tools an methods that ere desperately needed for individuals and groups during times of strife. He will also tell you that the larger the crisis, the more people it impacts and the longer the duration the more we need to rely not just on being tough, but rely on the assets that come with specific and targeted experience and credentials in psychology, behavioral science and human performance

"If you are someone who is experiencing a personal life crisis, an organization that is trying to navigate a crisis or a community that is trying to contain a crisis. I have the training and understanding to help you. If you are in a high-pressure situation and need to make sure that you are getting the most out of your own psychological, emotional, behavioral and physiological resources, I can guide you through. ." Dr. Josh states.

To learn more about Dr. Josh's work or how you can reach out, go here.



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