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AMD COVID-19 HPC Fund to Deliver Supercomputing Clusters to Researchers Combatting COVID-19 – HPCwire

SAN CLARA, Calif., Jun 1, 2020 AMD and technology partnerPenguin Computing Inc., a division ofSMART Global Holdings, Inc., announced that New York University (NYU), Massachusetts Institute of Technology (MIT) and Rice University are the first universities named to receive complete AMD-powered, high-performance computing systems from the AMD HPC Fund for COVID-19 research. AMD also announced it will contribute a cloud-based system powered by AMD EPYC and AMD Radeon Instinct processors located on-site at Penguin Computing, providing remote supercomputing capabilities for selected researchers around the world. Combined, the donated systems will collectively provide researchers with more than seven petaflops of compute power that can be applied to fight COVID-19.

High performance computing technology plays a critical role in modern viral research, deepening our understanding of how specific viruses work and ultimately accelerating the development of potential therapeutics and vaccines, said Lisa Su, president and CEO, AMD. AMD and our technology partners are proud to provide researchers around the world with these new systems that will increase the computing capability available to fight COVID-19 and support future medical research.

The recipient universities are expected to utilize the new compute capacity across a range of pandemic-related workloads including genomics, vaccine development, transmission science and modeling. Additionally, scientists from around the world conducting COVID-19 research can request access to the remote AMD-powered cloud HPC cluster at Penguin Computing by submitting proposals to[emailprotected].

University Engagement

The receiving universities are preparing their research plans and infrastructure now to receive the systems, including defining specific research projects that can have both immediate and long-term impact.

NYU

The COVID-19 pandemic has had a profound impact on higher education research, both in terms of its direction and the need for immediate results, so the timing of this donation is particularly fortuitous, and were tremendously grateful to AMD, said Russel Caflisch, director of the NYU Courant Institute of Mathematical Sciences. The computing resources donated by AMD will be put to use by NYU researchers from a wide range of disciplines in projects to address the many important facets of the COVID-19 crisis, including: discovery of drugs that may be therapeutic for COVID-19 and future SARS virus mutations, retrieval of relevant research results from the vast biomedical literature, analysis of medical imaging for screening of patients, and analyzing political attitudesand voting behavior in response to financial hardships.

MIT

Across MIT we are engaged in work to address the global COVID-19 pandemic, from that with immediate impact such as modeling, testing, and treatment, to that with medium and longer term impact such as discovery of new therapeutics and vaccines. Nearly all of this work involves computing, and much of it requires the kind of high performance computing that AMD is so generously providing with this gift of a Petaflop machine, says Daniel Huttenlocher, dean of the MIT Schwarzman College of Computing.

Rice

At the Center for Theoretical Biological Physics,Rice researcher Jos Onuchic is using his previous studies on influenza A as a guide to explore how the coronaviruss surface proteins facilitate entrance to human cells, the critical first step of infection. Another scientist, Peter Wolynes, is using principles from his foundational theories of protein folding to screen thousands of drug molecules and identify the best candidates for clinical tests based upon how well they bind to the viruss surface proteins.

The AMD gift will be truly transformational for Rices computational attack on COVID-19, said Peter Rossky, dean of Rices Wiess School of Natural Sciences. We have the methods to progress, but studies of large, complex systems are at the cutting-edge of computational feasibility. The AMD contribution of dedicated, state-of-the-art computational power will be a game changer in accelerating progress toward defeating this virus.

AMD Ecosystem Partners

AMD has joined with well-known HPC and AI solutions firm Penguin Computing to define, build, and deliver the on-premises systems and Penguins Penguin on Demand (POD) cluster, powered by AMD. Penguin Computings POD support will be collocated in data center space donated by DataBank. Contributions from Penguin Computing, NVIDIA, Gigabyte, and others are helping the AMD HPC Fund advance COVID-19 research.

Penguin Computing is looking forward to supporting and contributing to the COVID-19 research efforts through this AMD collaboration. We are committed to providing our applications and technology expertise in high performance computing, artificial intelligence and data analytics to both the University on-premises and our remote POD cloud environments, said Sid Mair, President, Penguin Computing Inc.

Ultra-fast data speeds and smart data-processing are key to delivering insights that science demands, particularly in these challenging times, said Gilad Shainer, senior vice-president of marketing for Mellanox networking at NVIDIA. NVIDIA Mellanox HDR 200 gigabit InfiniBand solutions provide high data throughput, extremely low latency, and application offload engines that accelerate bio-science simulations and further the development of treatments against the coronavirus.

Gigabyte is supplying its G290-Z21 compute nodes for the Penguin clusters, built around a single, 48-core AMD EPYC 7642 processor paired with eight Radeon Instinct MI50 GPU accelerators. The system R182-291 management nodes, also from Gigabyte, each utilize two 16-core, AMD EPYC 7302 processors.

AMD Commitment to COVID-19 Research

The AMDCOVID-19 HPC fund was established to provide research institutions with computing resources to accelerate medical research on COVID-19 and other diseases. In addition to the initial donations of $15 million of high-performance computing systems, AMD has contributed technology and technical resources to nearly double the peak system of the Corona system at Lawrence Livermore National Laboratory which is being used to provide additional computing power for molecular modeling in support of COVID-19 research.

About AMD

For more than 50 years AMD has driven innovation in high-performance computing, graphics and visualization technologies the building blocks for gaming, immersive platforms and the datacenter. Hundreds of millions of consumers, leading Fortune 500 businesses and cutting-edge scientific research facilities around the world rely on AMD technology daily to improve how they live, work and play. AMD employees around the world are focused on building great products that push the boundaries of what is possible. For more information about how AMD is enabling today and inspiring tomorrow, visit the AMD (NASDAQ: AMD)website,blog,FacebookandTwitterpages.

Source: AMD

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Testosterone Replacement Therapy Market 2019 Break Down by Top Companies, Countries, Applications, Challenges, Opportunities and Forecast 2026 – Cole…

A new market report by Market Research Intellect on the Testosterone Replacement Therapy Market has been released with reliable information and accurate forecasts for a better understanding of the current and future market scenarios. The report offers an in-depth analysis of the global market, including qualitative and quantitative insights, historical data, and estimated projections about the market size and share in the forecast period. The forecasts mentioned in the report have been acquired by using proven research assumptions and methodologies. Hence, this research study serves as an important depository of the information for every market landscape. The report is segmented on the basis of types, end-users, applications, and regional markets.

The research study includes the latest updates about the COVID-19 impact on the Testosterone Replacement Therapy sector. The outbreak has broadly influenced the global economic landscape. The report contains a complete breakdown of the current situation in the ever-evolving business sector and estimates the aftereffects of the outbreak on the overall economy.

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Leading Testosterone Replacement Therapy manufacturers/companies operating at both regional and global levels:

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Sales and sales divided by Applications:

The report also inspects the financial standing of the leading companies, which includes gross profit, revenue generation, sales volume, sales revenue, manufacturing cost, individual growth rate, and other financial ratios.

The report also focuses on the global industry trends, development patterns of industries, governing factors, growth rate, and competitive analysis of the market, growth opportunities, challenges, investment strategies, and forecasts till 2026. The Testosterone Replacement Therapy Market was estimated at USD XX Million/Billion in 2016 and is estimated to reach USD XX Million/Billion by 2026, expanding at a rate of XX% over the forecast period. To calculate the market size, the report provides a thorough analysis of the market by accumulating, studying, and synthesizing primary and secondary data from multiple sources.

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The market is predicted to witness significant growth over the forecast period, owing to the growing consumer awareness about the benefits of Testosterone Replacement Therapy. The increase in disposable income across the key geographies has also impacted the market positively. Moreover, factors like urbanization, high population growth, and a growing middle-class population with higher disposable income are also forecasted to drive market growth.

According to the research report, one of the key challenges that might hinder the market growth is the presence of counter fit products. The market is witnessing the entry of a surging number of alternative products that use inferior ingredients.

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Impact analysis of COVID-19 on Liquid Packaging Carton Global Market Analysis 2027 by Top Companies, Revenue, Emerging Trends – 3rd Watch News

Global Liquid Packaging Carton Market Analysis 2018-2027

Liquid packaging carton is a storage container designed to enable the safe transportation and storage of liquid products such as packaged water, juice, milk, and other dairy products, soft drinks, and others. The liquid packaging cartons are available in several shapes, sizes, and application types. Also, these liquid packaging cartons are easy to design and develop according to the manufacturers needs. The global liquid packaging carton market is anticipated to achieve a CAGR of around 5% over the forecast period, i.e. 2019-2027.

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Factors such as increasing the number of end-user industries dealing with liquid food products, the rising trends of aseptic-based packaging amongst manufacturers, and growing research and developmental activities for the innovation of packaging technologies are anticipated to contribute significantly towards the growth of the global liquid packaging carton market. Additionally, the increasing need for eco-friendly packaging amongst liquid food product manufacturers that can increase shelf life of the product as well as contribute to lower the transportation cost are some of the factors anticipated to drive the growth of the global liquid packaging carton market.

The global liquid packaging carton market consists of various segments that are segmented by material and by region. The material segment is further sub-divided into paperboard, polyethylene, and aluminum. The paperboard segment is further sub-divided into food & beverages and other end users. Out of these, the food & beverage segment is anticipated to hold the largest market share by the end of 2027. Additionally, the segment accounted for a value of around USD 5600 million in the year 2018 and is anticipated to cross a value of around USD 9000 million by the end of 2027 by growing at a CAGR of around 5.5% over the forecast period.

Based on region, the global liquid packaging carton market is segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa. The market in North America, which had accounted for around 11% market share in the year 2018 is anticipated to cross a value of around USD 2400 million by the end of 2027 by growing at a CAGR of around 5% over the forecast period.

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Top Companies:

Some of the affluent industry leaders in the global liquid packaging carton market are SIG Combibloc Group Ltd., Tetra Pak International S.A., Evergreen Packaging LLC, Refresco Group, Klabin SA, Greatview Beijing Trading Co., Elopak AS, and Nippon Paper Industries Co., Ltd.

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G3 Therapeutics and Juvenescence Limited Announce the Formation of Juvenomics, a Visionary Company Founded on Applying Deep Molecular Profiling and…

DOUGLAS, Isle of Man--(BUSINESS WIRE)-- Juvenescence Limited, a life sciences company focused on therapies to modify aging and increasing healthy human longevity, and G3 Therapeutics, a trailblazer biotechnology company leveraging biological big data for drug discovery and development, today announced the formation of Juvenomics Limited, a joint venture between the two parent companies. Juvenomics will focus on developing validated nutraceuticals and medicines to combat aging and aging-related diseases such as those of the musculoskeletal system. Juvenomics is built on the unique combination of G3 Therapeutics proprietary, multi-omic biological dataset, consisting of trillions of proprietary datapoints collected in the GLOBAL Clinical Study (NCT01738828) of over 7,500 patients, and the unique machine learning platforms assembled by Juvenescence. Juvenomics is also proud to announce the appointment of Dr. David Roblin MD FMedSci to its Board of Directors. David has an extensive background in the pharmaceutical industry with a proven track record as former President of R&D at Summit Therapeutics, Head of Anti-Infectives at Bayer, and Head of Research in Europe for Pfizer. He is currently COO at Juvenescence and the Chair of Scientific Translation at the Francis Crick Institute.

Szilard Voros, MD, FACC, FSCCT, FAHA, Founder and CEO of G3 Therapeutics commented: For the first time, biological big data - and genomics in particular - meets longevity science. Over the past 7 years, we have pioneered the use of unbiased biological big data for drug discovery and development, primarily focusing on cardiovascular and cardio-metabolic diseases. During the same period of time, the science of aging and healthy longevity has gone through its rites of passage and Juvenescence is paving the way in the application of the same scientific and medical rigor that is applied to all common, chronic diseases. In Juvenescence, we have found the perfect partner to work with to discover, develop and commercialize genetically validated nutraceuticals and pharmaceuticals to foster healthy aging and treat diseases of aging. Juvenomics is trailblazing the science of biological big data to bring revelatory new approaches to combat the aging process.

Gregory Bailey MD, Founder and CEO of Juvenescence Limited commented: At Juvenescence, we are very excited about this opportunity to work with G3. Since its inception Juvenescence has been at the vanguard of applying data science towards drug discovery and development. The depth of the patient derived database assembled by G3 is extraordinary and compelling. To have exclusive access to the existing data and the new data that G3 generates going forward for anti-aging and age-related diseases is a unique opportunity. This data gives us the ability to accelerate discovery and development of therapeutics to modify healthy aging.

About G3 Therapeutics

G3 Therapeutics is a global leader in the application of unbiased biological big data in transforming the drug discovery and drug development process. G3 Therapeutics has assembled a revelatory platform that utilizes deep phenotyping, deep molecular profiling and deep learning for the discovery, genetic validation and development of novel drug targets. G3 Therapeutics foundational biological big data platform has been built on the GLOBAL Clinical Study (NCT01738828), enrolling over 7,500 individuals from around the world. G3 Therapeutics deep molecular profiling approach includes whole genome sequencing, as well as the measurement of all other relevant omics measurements including DNA methylation, RNA sequencing, proteomics, metabolomics, and lipidomics. G3 Therapeutics has already discovered and patented relevant biomarkers and is starting the development of several novel drugs based on its proprietary platform and discoveries.

About Juvenescence Limited

Juvenescence Limited is a life sciences company developing therapies to modify aging and increase healthy human longevity. It was founded by Jim Mellon, Dr. Greg Bailey and Dr. Declan Doogan. The Juvenescence team are highly experienced drug developers, entrepreneurs and investors with a significant history of success in the life sciences sector. Juvenescence will create, partner with or invest in new companies with longevity-related therapeutics by in-licensing compounds from academia and industry, or forming joint ventures. Juvenescence believes that recent scientific advances have greatly improved our understanding of the biology of aging and seeks to develop therapeutics with the possibility of slowing, halting or potentially reversing elements of the aging process.

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Researchers find the worlds cleanest air at the tip of the planet – The South African

The worlds cleanest air, free from particles, more specifically, aerosols, caused by human activity was found over the Southern Ocean close to both Antarctica and Australia according to a study published this past week titled, Airborne bacteria confirm the pristine nature of the Southern Ocean boundary layer.

In an ever-evolving world, it is certainly difficult to find parts of the world that are untouched by human impact. This was the first study to measure the bio aerosol composition of the Southern Ocean, where the lower clouds over the Southern Ocean were found to be free of human activity and air pollution.

Co-author of the study, Thomas Hill stated, The Southern Ocean is one of very few places on Earth that has been minimally affected by anthropogenic activities.

Researchers thought that they might find traces of human DNA and bacteria. In fact, the only bacteria found in the region was linked to marine bacteria from the sea spray. The research findings are important to the science field as it disproves other studies that state that oceans in the Northern Hemisphere as well as the subtropics have microbes that drift in from upwind continents. The study revealed that aerosols were not travelling south and into the air as previously stated.

Air pollution is considered to be a global health crisis and claims seven-million lives each year, this according to reports released from the World Health Organisation (WHO). Burning fossil fuels does not only pose a threat to human longevity and quality of life but also has a detrimental effect on the environment which in turn, leads to warmer weather and climate change.

With more than 80% of people living in urban areas exceeding the WHO health guidelines an effort to reduce air pollution needs to be a priority.

This content has been created as part of our freelancer relief programme. We are supporting journalists and freelance writers impacted by the economic slowdown caused by #lockdownlife.

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Researchers can extend the lifespan of mice: Are WE next? – ISRAEL21c

The naked mole rat never develops age-related diseases. It stays active and enjoys good bone health, reproductive success and mental acuity for its lifespan of up to 30 years.

Two of many reasons for this creatures healthy longevity are its low body temperature and slow metabolic rate.

For the first time, researchers from the Institute of Gerontology in Kiev and Prof. Vadim Fraifelds Lab for the Biology of Aging at Ben-Gurion University of the Negev in Israel have replicated those conditions in lab mice. A naked mole rat generally lives about eight times longer than a mouse despite its similar size.

The research results, published in Biogerontology, have intriguing implications for increasing longevity and decreasing major pathologies in humans as well.

According to the scientists, the naked mole rats burrows are poorly ventilated, keeping oxygen levels are low and carbon dioxide levels high. This may cause the reduction in the naked mole rats body temperature by 3-4 degrees as compared to mice and slow its metabolism significantly.

A naked mole rat in its burrow. Photo by Neil Bromhall via Shutterstock.com

Subjecting laboratory mice to the same conditions called a hypoxic-hypercapnic environment (HHE) successfully reduced their body temperature and metabolic intensity for weeks and even months.

And the mice in the HHE voluntarily consumed less food, which is one of the well-known factors in increased longevity.

Unexpectedly, the HHE accelerated skin wound healing, despite the lower energy expenditure, the researchers also noted.

All in all, a chronic exposure to HHE offers a potential of being a lifespan-extending intervention as well as an efficient tool for treating the overweight and associated metabolic disorders.

The scientists explain that at one point in history, the Earth contained much lower levels of oxygen and higher levels of carbon dioxide.

There is still some memory in our cells of that period and therefore it should be possible in the future to induce such a state for longer periods, they said.

Moreover, they believe that HHE conditions could be used to help fight obesity, diabetes and perhaps even cancer.

Secrets of long life

The naked mole rat (Heterocephalus glaber), a rodent native to East Africa, has long been the subject of study because of its unusual healthy longevity and particularly its resistance to cancer.

In 2012, Tel Aviv University evolutionary biologist Dorothee Huchon and colleagues at the Texas Health Science Center and the City College of New York determined another reason for the naked mole rats unusual life expectancy: very high levels of a neuro-protective protein called Neuregulin 1 (NRG-1) in its brain.

Because NRG-1 is also found in the human brain, Huchon and her fellow researchers suggested that learning more about how aging and NRG-1 are related could be significant.

Fraifeld studies many aspects of human aging genomics. Graduate students in his Lab for the Biology of Aging at BGU won an award for their study on longevity genes, genetic protective factors that some people are lucky enough to inherit.

By modulating the activity of these genes in advanced age, it could be possible to combat major diseases.

Although an apparent paradox, it appears that the most effective way to delay or even to avert age-related diseases is to live longer, Fraifeld told ISRAEL21c.

Another prominent Israeli longevity researcher, Bar-Ilan Universitys Haim Cohen, recently published a study showing that SIRT6, considered a longevity-related protein, is involved in regulating biological processes including aging, obesity, insulin resistance, inflammation and metabolism. His team hopes to identify therapeutic approaches that target and activate SIRT6.

Ben-Gurion University researcher Debbie Toiber specializes in studying SIRT6 and DNA repair as models of age-related diseases.

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June is Alzheimer’s and Brain Health Awareness Month – messenger-inquirer

With June comes hot sunny days, beautiful rolling green fields, and lightning bugs. It is also Alzheimers and Brain Health Awareness Month. June is a wonderful month to create long-lasting memories with friends and family. Many of us go on vacation or enjoy a weekend cookout or two. How precious are the memories we build; they are more valuable than any worldly possessions that we can gain.

Unfortunately, our memories are just like anything else as they can vanish. I watched this happen to my grandmother, and it was a painful experience. My grandmother loved to cookand she could make the best fried chicken, roast, and potatoes. However, we started to notice a difference in her ability to cook around the last decade of her life. She was forgetful. The beginning signs of something going wrong were very subtle. As time went on, the symptoms became more obvious.

At the end of my grandmothers life, she suffered from end-stage dementia. She could not remember people, things, or past events. When I would visit her in the nursing home, she would gaze out as if no other person were in the room with her. It was painful for all the family to see her like that. In the end, the disease progressed to the point that she would not eat or drink. In November of 2017, my grandmother lost her battle to this disease.

According to the Alzheimers Association, beginning symptoms of Alzheimers may include forgetfulness, an inability to complete daily tasks, misplacing or losing things, and a withdrawal from social activities These signs can be very subtle at firstand will gradually become more evident over time.

There is still so much about Alzheimers that is unknown. The brain is a complex part of our body. The way it functions is miraculous and mysterious. Sadly, so are diseases that impact it. Although science has allowed us to understand more about the human brain, there is still more that needs to be understood before we can defeat horrible diseases.

Overall, the best way to promote brain-health longevity is to exercise and stay active. The CDC also recommends learning new things and staying connected to loved ones. Furthermore, regular check-ups with a medical provider can help ensure brain-health, too.

One of the most valuable things we have as human beings is the ability to remember. My grandmother, like millions of other men and women, lost her ability to remember because of a horrible disease such as dementia. My prayer is that one day diseases such as these will be defeated.

For more information about this topic, please visit http://www.www.alz.org.

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Dangers of ‘over bathing’ shared | Local Columnists | union-bulletin.com – Walla Walla Union-Bulletin

Part 1

From the Washington Statesman, June 7, 1862, Walla Walla, Washington Territory:

Over Bathing If a fish is deprived of its scales, it will be chilled to death; and reasoning analogically, and knowing, too, that the human skin scales are destroyed by the alkali of the soap, a man may wash himself too much may actually wash away the scales of his body, leaving the pores so unprotected against heat and cold and obstructions, that death will inevitably ensue; indeed, physiological research proves that if a third of the skin is removed from the body by scalding or otherwise, a fatal termination is unavoidable.

Observant persons know how soon the skin becomes pale, shriveled and tender, even on the harder hands, if kept a great deal in cold water. These are suggestive considerations for those who believe that continued water sloshings are indispensable to health and longevity Halls Journal of Health.

From the Washington Statesman, June 14, 1862, Walla Walla, Washington Territory:

Stabbing A man named Purdy was killed by a Spaniard in this county, on Wednesday last. They got into a dispute about a blanket, during the Spaniard drew Purdys knife from his belt and stabbed him to the heart. The Spaniard escaped.

From the Washington Statesman, June 21, 1862, Walla Walla, Washington Territory:

Early Vegetables No country that we have even been in is better adapted to the growth of vegetables than the Walla Walla valley. The snow had scarcely left the foothills in the spring when lettuce, radishes, onions and rutabagas were abundant in market.

New potatoes have been in market more than a week. This beats the lower country by at least two weeks. The Oregonians are in the habit of shipping their early vegetables from California. Henceforth we would recommend them to ship their supplies in this line from this valley.

Susan Pickett was professor of music at Whitman College from 19812018. She is the author of Marion and Emilie Frances Bauer: from the Wild West to American Musical Modernism a biography about two women born in Walla Walla whose careers in the New York City music scene spanned 18961955.

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The resiliency of white-tailed deer – – Adirondack Almanack

Editors note: This is part two of a two-part series.

Deer appear in paleolithic cave paintings at Altamira, on the north coast of Spain, going back 36,000 years.

The white tailed deer has been in North America for about 4 million years, making the white tail one of the real veterans of nearly all varying habitats in North America, ranging from Nova Scotia west to southern Alberta, sweeping south into Central America, with gaps west of the Rockies.

To put that in perspective, modern moose have only been in North America about 15,000 years, having migrated through Berengia about the same time the ancestors of native Americans began to trickle across.

In North America, moose have much more serious problems with winter ticks in affected habitats than deer have. For example, deer go through winter with an average of about 300 winter ticks, while moose may accumulate from 10,000 to 90,000 winter ticks, a condition which is probably a serious factor in why moose are in trouble all along the US-Canadian border from Maine to Minnesota. Winter ticks are beginning to show up in New York as well. Are white tails simply more efficient groomers, or could there be a connection related to longevity in habitat, and the ability of animals to adapt to parasites and challenges not found in previous habitats?

Deer on the food chain

Deer have played a major role in human nutrition and survival for a very long time. European immigrants to America, learned from native Americans about utilizing all parts of the white tail. Deer numbers rose and fell in the 19th century with market hunting by both native Americans and the growing numbers of settlers and immigrants, joining individual hunting, along with deforestation and destruction of deer habitat. State regulation of hunting slowed down the hunting free-for-all, and helped increase deer numbers, but two other factors in the first decades of the 20th century led to an explosion of deer.

Everything in nature is connected. The increasing suburbanization and the expansion of farming in America had the effect of moving more people into deer habitat, while introducing deer to our orchards, crops and gardens, thereby increasing their ability to making a living and reproduce. The more deer saw, heard and smelled human activity, without being shot at, the more it helped to inure them to the dangers of our presence.

In an environment without humans, gray wolves tend to be the number one controller of both deer and western coyotes, the latter in competition for safer prey, smaller than moose, elk and bison, but the accelerating persecution of gray wolves, which included poisoning campaigns and bounties led to an explosion of both deer and coyotes. Predators tend to strengthen the health of prey populations by detecting and eliminating disease and weakness. An unfortunate example of why we shouldnt eliminate predators is the reappearance of chronic wasting disease, an infectious disease in deer which is slowly spreading in areas where wolves had historically kept it in check.

As wolf habitat in the lower 48 dwindled to Minnesota, the only state which kept the Federal wolfers out, western coyote numbers exploded out west, leading to a manifest destiny in reverse, with coyotes increasingly moving east under and over the Great Lakes, exploiting available wolf habitat in the lower 48, and causing further hybridization of Algonquin wolves in Ontario and Quebec, already averaging 20% western coyote going back tens of thousands of years, long before there were any humans in North America.

Yes, you read that correctly. Wolves have the most dangerous job in nature for two reasons. An alpha female may deliver 4 to 7 pups every Spring. While it is much safer for wolves to go after deer, snowshoe hare and beaver, pressure to produce food compels wolves to go after much larger, more dangerous prey, such as moose, elk and bison. Moose, for example, are so dangerous in defending themselves, that wolves test 20 moose for each one they decide to take a chance and attack. As though that factor in intself didnt make a wolfs life dangerous enough, in wolf economics, the pack has to defend a territory large enough to contain enough prey for the pack to make a living, and if a neighboring packs territory is not producing, theyll be invading another packs territory, which will result in wolves killing each other over access to prey. Add these factors to our inclination to shoot and trap wolves, and wolves are lucky to reach their fifth birthday in the wild.

Gray wolves tend to kill coyotes, just as coyotes kill fox, routinely and opportunistically eliminating the smaller predator, as a means of creating a larger base of smaller, safer prey, but starting in Minnesota and heading east over Lake Superior, young male wolves, who disperse from, in other words, leave Mom and Dads territory, to seek an unguarded territory, or a territory they may be able to take over, may discover that female wolves dont generally disperse as far as males, so they may end up defending a territory no other wolf wants, and they may end up mating with a female coyote.

Deer hunters tend to bemoan the impact of eastern coydogs, more accurately termed coywolves, because of their hybridization with Algonquin wolves, on the deer population in the Northeast. But the coyote impact on deer numbers is much greater on fawns than it is on adults, partly thanks to our assistance with traffic accidents supplying deer as roadkill. A study by SUNY College of Environmental Science & Forestry a few years back concluded that, excluding fawns, 92% of deer eaten by coyotes in New York were killed by cars. About 60% of fawns reach maturity, while 80% of fawn mortality is caused by predators, including bears, wolves, coyotes, cougars, bobcats, lynx, fishers, eagles, and even foxes. Other fawn mortality factors range from car accidents to getting caught in fencing or under farm equipment, or natural causes like starvation and drowning.

More recently, hunting generally, and deer hunting in particular, which peaked among baby boomers in 1982, while rising in some states, and falling in others, is in a fairly steady decline nationwide. Weve lost 10% of all hunters in the last ten years, with less than 4% of Americans involved in hunting today, at exactly a time when, having largely eliminated wolves, natures tool for deer control, we need more human hunters to control deer numbers. For those concerned about health and red meat, venison is much leaner than beef, and probably half the calories.

Controlling deer without natural predators is no easy problem. Highest deer densities are often found in thickly settled suburban areas, where it is unsafe, and often illegal, to fire rifles within 500 feet of a dwelling, or shoot arrows, and the deer take a heavy toll on gardens and landscaping generally. Some towns and villages are experimenting with immunocontraception, to cut down the number of does breeding. Such methods may require multiple doses, and may only be good for a couple of years. Other towns employ specially vetted deer hunters to control local deer populations. Habitat carrying capacities, which increase as deer learn how to eat more human planted and invasive vegetation, determine how many deer a particular area can support, which means as you eliminate deer, other deer come in from surrounding areas.

This is a lesson we seem to refuse to understand. As we eliminate animals from habitat, for example beavers, they are replaced by other beavers who are attracted to the habitat for the same reason the removed beavers were. Its good beaver habitat. The same thing happens with deer, but because deer eat a much wider range of vegetation, and learn to eat our gardens, as well as invasive plants, they expand the areas they can make a living in. We always treat the symptom, rather than the cause, and end up throwing natures balance further out of whack.

In New York State, we have just under a million deer, with 60 to 70 thousand in the Adirondacks, and about 70,000 vehicle deer collisions statewide annually. Hunters took about 225,000 deer in New York State in 2018. As elegant and visually appealing as white tails are, their lives tend to be violent and short, with the average age of death for deer being about 3 years old. As a sign of the times, the mosquito, which for 80 years was the most likely animal to be involved in human mortality in the lower 48 states, just as it is in most moderately temperate countries, was knocked out of first place by the white tailed deer, because of the number of people killed in accidents involving deer.

Photos by Joe Kostoss, Eye in the Park, courtesy of the Adirondack Wildlife Refuge

Steve and Wendy Hall run the Adirondack Wildlife Refuge and Rehab Center in Wilmington. They've been rehabbing and releasing wild animals for over 45 years, specialize in predators, keep wolves as the cornerstone of their educational program, and have lived in the Adirondacks for the past 20 years. The Adirondack Wildlife Refuge became a non-profit about 10 years ago.

Visit http://www.AdirondackWildlife.org to learn more.

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Precision Medicine Software Market (impact of COVID-19) Growth, Overview with Detailed Analysis 2020-2026| Syapse, Allscripts, Qiagen, Roper…

Global Precision Medicine Software Market (COVID-19 Impact) Size, Status and Forecast 2020-2026

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Chapter 1: Global Precision Medicine Software Market Overview

Chapter 2: Precision Medicine Software Market Data Analysis

Chapter 3: Precision Medicine Software Technical Data Analysis

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Chapter 11: Global Precision Medicine Software Market New Project Investment Feasibility Analysis

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