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High Blood Pressure on the Rise: How to Manage Yours – Healthline

New research is reporting that uncontrolled high blood pressure is a growing problem among adults in the United States.

The findings were presented this week at the virtual American Heart Associations Hypertension Scientific Sessions 2020.

The report, which hasnt been peer-reviewed or published yet, paints a bleak picture of the current landscape.

The data collected up until 2014 showed that an increasing number of Americans were managing their blood pressure, but data from 2015 and 2016 showed a drop of more than 6 percent.

Additionally, the percentage of U.S. adults with controlled high blood pressure dropped by 11 percent between 2013 and 2018. The percentage of adults in their 40s and 50s with controlled blood pressure also fell nearly 10 percent between 2009 and 2018.

This study should serve as a wake-up call to all physicians, Dr. Guy L. Mintz, director of cardiovascular health and lipidology at Northwell Healths Sandra Atlas Bass Heart Hospital in New York, told Healthline.

Alarms should be going off because we are doing a substandard job of diagnosing hypertension and are failing at the effective treatment and control of hypertension, he added.

Dr. Brent M. Egan, who is the studys lead author, a professor at the University of South Carolina School of Medicine, and the American Medical Associations vice president of cardiovascular disease prevention, told Healthline that its crucial for people to understand that maintaining healthy blood pressure is an ongoing process.

Individuals with high blood pressure need to be aware of their condition, so they can take steps to control it. For many individuals, management includes both a healthy lifestyle and medications, Egan said. Effective self-management includes taking necessary and sufficient medication together with a healthy lifestyle to control blood pressure. [It is] a consistent, long-term, ongoing process and not an episodic event.

Egan points out that blood pressure thats not managed well can increase the risk of heart attack, heart failure, and stroke, due to the way hypertension can affect the blood vessels and heart.

Other somewhat less serious side effects can include headaches, fatigue, reduced exercise tolerance, and blurred vision.

A wrinkle that can lead to confusion among doctors and patients is the fact that theres more than one way to get a blood pressure reading, said Mintz.

While physicians have taken blood pressure readings using a stethoscope for years, there is a different method.

Its called ambulatory blood pressure monitoring, which takes readings for a 24-hour period, and is considered to be more accurate.

The challenge to make ambulatory blood pressure management the gold standard for diagnosing hypertension involves a focused education against the ingrained stubbornness of the majority of physicians, said Mintz. Many physicians balk at the cost of an ambulatory blood pressure monitor, which ranges from $1,500 to $3,000 depending on the type of monitor. The reluctance to purchase an ambulatory blood pressure monitor is also related to the limited insurance coverage for this procedure. However, recently there has been improved coverage.

Egan said that its important for people to know their blood pressure numbers by getting a reading at least once per year.

They should also be aware of which blood pressure category normal, elevated, stage 1 hypertension, or stage 2 hypertension they fall into.

From there, its important to follow up with a doctor to determine which lifestyle interventions or medications might be needed to manage their blood pressure.

For many patients, training in self-monitored blood pressure, including recording values and relaying those to the healthcare team is beneficial in improving blood pressure control, said Egan.

But it isnt just the individual and their doctor who can help, says Egan. Family members can also be a great support.

Lifestyle changes are better done together, he said. Walk together. Have healthy meals and snacks together. Sometimes, help getting medication and keeping medical appointments require assistance with transportation or costs.

Egan also notes that the American Heart Association (AHA) and the American Medical Association (AMA) have launched a national initiative, known as Target:BP, which is trying to help medical providers across the country improve blood pressure control rates.

He said healthcare professionals can also utilize programs proven to improve blood pressure control. That includes the AMAs MAP BP program, which stands for measure accurately, act rapidly, and partner with patients and families.

The AMA and AHA are partnering on Target:BP and the MAP BP program to improve hypertension control rates nationally and to improve equity in blood pressure control and cardiovascular outcomes, Egan noted.

Finally, its critical for everyone to be aware of the serious risks associated with hypertension.

Hypertension remains the silent killer because there are no symptoms and its a major risk factor for heart attack, stroke, and progressive kidney disease, said Mintz.

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We can do more to help the elderly cope with the COVID-19 crisis – The Jerusalem Post

Does the society really wish to help the elderly cope with the COVID-19 crisis? If so, why does not it address the problem at the root?There is a lot of uncertainty about the COVID-19 statistics. Yet, at least one piece of evidence is clear: older persons are at the greatest risk. And this simply means that the aging process and its resulting multiple aging-related diseases (multimorbidity) are the main determinants for disability, hospitalizations, severe clinical outcomes and deaths with COVID-19 and thus are responsible for the devastating damages to the economy and the entire society. There is now a broad social realization that the elderly are the main risk group that needs to be protected. Then why not make the next logical step and realize the crucial role of the degenerative aging processes, the diminishing resilience and immunity of the aging persons, and the corresponding vital need to therapeutically ameliorate these degenerative aging processes to improve immunity and resilience? This could help mitigate the present crisis and avert future ones. This is the essence of the geroscience approach to the COVID-19 crisis that aims to therapeutically improve multiple aging-related diseases by intervening into their underlying aging processes, such as the process of immunosenescence. A recent position paper Geroscience in the Age of COVID-19 published in the prestigious scientific journal Aging and Disease by some of the leading figures in the field of geroscience, from the US and Israel, promotes the geroscience-based preventive interventions. In addition to the healthy lifestyle (such as exercise, sufficient sleep and balanced nutrition) known to improve immunity in older persons, the geroscientists advocate for expanding the testing of existing drugs with established safety profiles that can potentially improve the biology of aging, immune mechanisms and resilience (the so called geroprotectors). These include such medications as metformin, rapamycin and their analogues, as well as NAD boosters, senolytics, biological immuno-modulatorors and other prospective geroprotective agents. These interventions showed promise in animal studies and some emerging human trials, though the scientists caution that so far no such treatments have yet been approved as geroprotectors for use in humans. Hence, self-medication with any of these substances is highly discouraged. Yet, the broader clinical testing of the existing, potentially geroprotective drugs, as well as developing new drugs targeting the aging processes, can be an effective long-term line of defense. Alongside the therapies, the geroscientists also advocate for the broader introduction of measurements (biomarkers) of aging, especially measurements of the deteriorating immune system, as potentially powerful means to predict the risks for the elderly, improve treatments and allocate resources for the protection of those who are most in need of it.THEN WHY not support and advance this research? Experience shows that it is not sufficiently supported. Vast funding is now allocated to researching and developing treatments for COVID-19, including some rather unorthodox and uncertain treatments. The calls for research proposals on COVID-19 now mainly focus on reactive treatments and vaccines. But there is insufficient realization that many reactive treatments and vaccines for COVID-19, whenever they are developed, will likely have diminished safety and efficacy in elderly patients who are at the highest risk, precisely because of their impaired immunity and resilience that geroscience aims to enhance. Yet very little support is explicitly announced for developing preventive geroscience-based interventions for improving the underlying aging health. Just compare the over $3.6 billion allocated by the NIH for the COVID-19 response, with only a few million for geroscience-oriented approaches called for by the National Institute on Aging within the NIH. In other places, such as the EU and Israel, such calls for preventive aging interventions are even more difficult, next to impossible, to find. The public awareness and support of such preventive interventions are also comparatively minuscule, compared to some of the massively publicized research directions such as vaccine development. Is the lack of attention to this approach due to our entrenched psychological reluctance to face our aging process that spills over to science? Is it due to ageism in healthcare that generally discriminates against or ignores the special concerns and needs of older persons? Is it the reluctance to think holistically and for the long term? Whatever the psychological impediments, the scientific community and the wide public should think rationally and proactively and give a strong focus and support for aging health interventions. cnxps.cmd.push(function () { cnxps({ playerId: '36af7c51-0caf-4741-9824-2c941fc6c17b' }).render('4c4d856e0e6f4e3d808bbc1715e132f6'); });If there is a lesson to be learned from this crisis, it is arguably the realization of the need to therapeutically address degenerative aging processes to prevent aging-related ill health as a whole. This understanding should translate to public health and research policies supportive of geroscience research, development and clinical application, improving the funding, incentives, education and institutional and public support for the field. Public advocacy should play an essential role for the realization of these goals. An example of such an advocacy effort is the public initiative for Enhancing research, development and education for promoting healthy longevity and preventing aging-related diseases advocated by the associations Vetek (Seniority) the Movement for Longevity and Quality of Life and Disabled, Not Half a Person. With sufficient support and deployment, the preventive geroscience approach may help avoid or mitigate the effects of devastating crises of aging-related ill health presently and for the future.The writer, a PhD, is the chief science officer of Vetek (Seniority) Association the Movement for Longevity and Quality of Life and Disabled, Not Half a Person, Israel.

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Healthy Snacks Market to Worth USD 108.11 Billion by 2027 | Fortune Business Insights Wall Street Call – Reported Times

Sep 15, 2020 10:00 AM ET iCrowd Newswire Sep 15, 2020

The global healthy snacks market size is anticipated to rise remarkably on account of the increasing health consciousness among consumers and the rising prevalence of quality lifestyle. These Snacks are a quick and affordable way of sufficing to the nutritional needs of the body. As per a recently published report by Fortune Business Insights, titled, Healthy Snacks Market Size, Share & COVID-19 Impact Analysis, By Type (Meat Snacks, Nut, Seeds & Trail Mixes, Dried Fruit Snacks, Cereal & Granola Bars, and Others), By Distribution Channel (Supermarket/ Hypermarket, Specialty Stores, Convenience Stores, and Online Retails), and Regional Forecast, 2020-2027, the value of this market is expected to rise from USD 78.13 billion earned in 2019 to USD 108.11 billion by the end of 2027. The market is likely to exhibit a CAGR of 4.2% during the forecast period set between 2020 and 2027.

The world economy is facing a major downfall owing to the current coronavirus pandemic. Most businesses are at temporary halt and the others who are operating in the four walls of their homes are barely able to manage meagre revenue. The healthcare sector is facing major crisis owing to the increasing number of positive coronavirus cases and lack of beds and medical aid to offer treatment. The governments of various nations are investing massively on the research and development of an antidote to fight back the covid-19 pandemic and we soon hope to overcome this situation.

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The report answers the following questions:

Drivers & Restraints-

Rising Inclination towards Healthy Food to Add Impetus

The increasing prevalence of chronic and acute diseases among people irrespective of age is a key factor propelling the adoption of healthy food. This stands as a major factor boosting the global healthy snacks market growth. In addition to this, the rising evolution of the food industry and the advent of various food and snacks varieties such as flavors, shapes, sizes, and nutritional value is also adding impetus to the market. Besides this, the advancement in food processing and preservation technology will also aid in the expansion of the market.

However, factors such as processing-related challenges, moisture retention as a result of sugar and fat reduction, and low shelf life of snacks highly rich in fruit and vegetable content may pose major challenges to the market growth. Nevertheless, the growing popularity of functional and convenience foods and the increasing adoption of on-the-go and ready-to-eat snacking, coupled with the increasing awareness among health conscious consumers are expected to create lucrative growth opportunities for the market in the coming years.


Nut-based Snacks segment to Cover Largest Share Owing to their High Protein Content

Based on segmentation by product type, this market is holding major shares from the nut-based snacks segment. This is owing to the high protein content present in nuts, as well as other high nutrient content such as antioxidants and fibre.

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List of the Key Players of the Healthy Snacks Market include:

Regional Analysis-

Europe Emerged Dominant Owing to Increasing Popularity of On-the-go Nutrition

Geographically, Europe covered the largest healthy snacks market share with a revenue of 31.06 billion earned in 2019. The growth of this region is attributed to the presence of a majority of health conscious people with hectic schedules and busy lifestyles. The advent of on-the-go nutrition and functional food products has propelled the need for healthy snacks, thereby augmenting the regional market.

On the other side, the market in Asia Pacific is likely to showcase the fastest growth in the coming years on account of the rising disposable incomes of people, increasing adoption of healthy lifestyle, and the growing popularity of food products that promote well being, known as better-for-you products.

Competitive Landscape-

PepsiCo., Inc. is Holding Leading Position Owing to New Product Launches

As of 2019, PepsiCo., Inc. is the leading player of this market. Most of the players functioning in the market for healthy snacks are engaged in the manufacturing of new snacks with unique flavors and ingredients so as to attract more revenue and gain a competitive edge in the market. The other players are focusing on collaborative strategies such as joint ventures, contracts and agreements, partnerships, and others to gain a competitive edge in the market during the forecast period.

Major Industry Developments of this Market include:

September 2019 A new brand of refrigerated products was launched by Tyson Food Inc., providing natural food benefits in their products.

October 2017 A new range of protein-enriched snacks called Proteinex Bytes was launched by Danone S.A. in India for expanding its business.

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During the Covid 19 Pandemic, Canadians Who Maintain a Healthy Body Weight Enjoy Better Physical and Mental Health – Canada NewsWire

MONTREAL, Sept. 15, 2020 /CNW/ - During the Covid 19 pandemic, 30% of Canadians have reported gaining weight during just the first few months. This is worrisome since obesity has been shown to be associated with more serious Covid 19 infections. In addition, new data fromCanadians who participated in a web-based health promotion program also demonstrated that during the pandemic adults with an ideal body weight, (Body Mass Index, or BMI of 18.5-24.9 kg/m2) suffered less from mental health issues including poor sleep, increased stress, and symptoms of depression. They were also up to three times more physically active than heavier individuals.

To help Canadian adults lose their "Covid 19 pounds" the MissionVAV Health Program will launch the Drop 5 Mission on September 21. This on-line weight management program, proven to help participants lose 5% of their weight and keep it off,is funded by Veterans Affairs Canada (#). It is designedto help individuals learn strategies that are essential for long-term weight management. The program combines education, digital tracking, social support and personalized health coaching.Given social isolation, health coaching will be provided by medical student volunteers from McGill University.

Dr Steven Grover, a Professor of Medicine at McGill, and one of the leaders of this program noted: "Health promotion and disease prevention are skills that most doctors struggle with. This is a win/win as medical students develop the skills to help their future patients adopt healthy lifestyle habits while teaching Drop 5 participants to manage the challenges associated with maintaining a healthy weight.

The Mission launches on Monday, Sept 21. Veterans and other Canadians who want to learn how to drop pounds (or inches) are welcome to joinand it's

#Grover S, Lowensteyn I, Marchand S, Dancausse S, Soussan E, Remple P, et al. The Evaluation of a Web-Based Weight Loss Program Among Military Personnel at CFB Halifax. Can J Diabetes. 2014;38(5): S38.

#Knuper B, Shireen H, Carrire K, Frayn M, Ivanova E, Xu Z, et al. The effects of if-then plans on weight loss: results of the 24-month follow-up of the McGill CHIP Healthy Weight Program randomized controlled trial. Trials. 2020; 21: 40.

#Barbels Studies

DND Abstract

SOURCE McGill Comprehensive Health Improvement Program (CHIP)

For further information: Dr Steven Grover, [emailprotected], 514-791-5688

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Long-Term Effects Of Diabetes To Your Body – – E/The Environmental Magazine

Diabetes is a lifelong condition that can make you susceptible to illnesses and diseases and is caused when a persons blood sugar levels become too high. Diabetes and pre-diabetes are conditions said to affect up to fifty percent of the population of the United States. Diabetes can hinder the quality of a persons life massively. It is critical that in order to live a long, healthy life, you do not consume sugary foods all of the time, otherwise, you may end up with diabetes, which during this current global pandemic, is contributing to high mortality rates. Diabetes must not be allowed to take over your life.

Diabetes is a condition with two main types. There is type one diabetes, which is when the bodys immune system begins to attack and destroy the cells that produce insulin type one diabetes is the most dangerous and the one that can cause the most amount of problems. Type two diabetes is when your body does not produce enough insulin and the bodys cells do not react to insulin. Type two diabetes is the most commonly found type of diabetes throughout the world, with over ninety percent of cases in the United Kingdom being attributed to type two diabetes.

Before moving onto the long-term effects that diabetes can have on your body, it is first important to mention the use of oral medication in the treatment of diabetes. Oral medication can be very successful in treating cases of diabetes and is the most commonly used method of treatment. When oral medication is used in combination with exercise and a healthy lifestyle, it can be very effective. One such medication, Dulaglutide, which is sold under the Trulicity brand name, is commonly used around the world to treat type 2 diabetes and helps to keep your blood sugar in check. However, the reason that online medication specifically has been mentioned, is that in some cases it may be counterproductive and illegal. You should only order online medication for your diabetes if your doctor has recommended it to you. You must not treat yourself, as self-treatment without medical intervention can have serious consequences on your health. You will likely not be a doctor, and no matter how many blog posts or forums you have read you do not know enough to treat yourself. Self-treatment can be a detriment to your recovery and can actually hinder it.

As diabetes increases your blood sugar and makes it higher than it should be, it can cause, after many years, serious problems in your body. Diabetes can harm your eyes, your kidneys, your nerves, your heart, your skin, your blood vessels, and many other parts of your body. The long-term effects of untreated diabetes can be very damaging and cause significant side-effects that can massively hinder your quality of life and in some cases leave you paralyzed. Below you will find the long-term effects of diabetes if left untreated. Always treat your diabetes never allow it to come to what is below:

Diabetes can cause significant eye problems and can directly contribute to blindness. The first sign that diabetes is causing you problems with your eyes is that you have trouble seeing during night time and your eyes become sensitive to light if you have never experienced these before, you may be suffering from diabetes. It can also lead to blindness and is very common among untreated diabetes patients.

Those who suffer from diabetes may go on to develop nasty sores, infections, and illnesses if the sores and infections go on for too long and are not treated, you may have to have the parts affected amputated. Infection also causes pus oozing, pain, and itching, as well as inflammation.

Having diabetes means you may not be able to control your blood pressure and your cholesterol levels. This can mean you may be more susceptible to a heart attack, angina, stroke, and other heart-related conditions it can also make the blood flow from your heart to your legs and feet much more difficult, which in some cases, can result in further amputation.

The nerves within your body can become very damaged as a consequence of untreated diabetes and you can begin to feel sensations such as tingling and loss of feeling. Nerve damage in male diabetes patients can also make it harder to grow and maintain an erection. If the nerve damage goes on and becomes too severe, you may become paralyzed in the parts of your body experiencing the nerve damage.

Food digestion can be hindered when you suffer from diabetes, and you may have trouble and weakness in your bowel movements. Diabetes can be very harmful to your digestive system and can wreak absolute havoc on it. Diabetes can be a big problem when it comes to digestion.

Kidney damage is another problem commonly associated with high levels of blood sugar. Your kidneys may not work as well as they once might have and could even stop working altogether. This could result in dialysis or a kidney transplant, both of which can hinder your quality of life massively and leave you in severe pain for the rest of it.

Mental health problems have been linked to diabetes patients through studies and research. Depression and anxiety have been said to be heavily linked to diabetes and it is even said that the two conditions go hand in hand. Patients who suffer from diabetes are more likely to experience depression and anxiety than those who do not. Mental health problems, in combination with the previously mentioned conditions, can absolutely ruin your life and leave you a shadow of your former self. Rather than allowing diabetes to get this bad and completely ruin your life, seek treatment. Treatment for diabetes can consist of some simple lifestyle changes and some medication. Seek treatment and your symptoms will be reduced and you may be able to fight off diabetes.

Now, with the help of this page, you know everything that there is to know about the long-term effects of diabetes. Treatment is essential and you mustnt suffer silently with the condition as if you do you can do yourself more harm than you could possibly imagine.

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Long-Term Effects Of Diabetes To Your Body - - E/The Environmental Magazine

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Dalwhinnie Farms Announces Grand Opening of Aspen Storefront, Reimagining the Traditional Cannabis Dispensary – Business Wire

ASPEN, Colo.--(BUSINESS WIRE)--Purveyor of fine Colorado cannabis, Dalwhinnie Farms, announced today the grand opening of its luxurious Aspen flagship boutiqueproviding an upscale shopping experience unlike any other.

Dalwhinnie Farms reconceives the standard dispensary model as an immersive, upscale experience, aiming to reignite the joy of shopping for cannabis as customers are encouraged to browse a specifically curated selection of designer apparel, jewelry and home goods in addition to top-of-the-line cannabis products and showpiece accessories from all over the world.

Every detail of the store is carefully designed to create an elite shopping experience that aligns with the retail standards of Aspen, said Terrance Mendez, Chief Executive Officer. Our goal is to destigmatize and demystify cannabis, normalizing it as part of a healthy lifestyle, and create a destination where the cannabis aficionado can enjoy a unique and exclusive buying experience.

Dalwhinnie Farms cherishes Colorados western heritage. The selection of branded craft cannabis is grown to exacting standards at the companys advanced cultivation facility that shares its grounds with a 210-acre working ranch.

The storefront, conceptualized in partnership with Terra Rose Design Labs, pairs modern elements with classic design pieces. The new merchandise mixes with rustic aged leathers, brass accents and antique mirrors to fit seamlessly into the Aspen aesthetic.

By reimagining the dispensary layout, weve achieved a shopping experience that invites the customer to shop, explore and return for more. The design ushers in a new era of cannabis retail, raising the bar and accomplishing a look and feel that rivals any mainstream store in Aspen, Mendez added.

Cannabis has been legal for quite some time, yet traditional dispensaries can still feel taboo, said Ashley Grace, Chief Revenue Officer. With our Aspen store, we are removing this barrier by offering premium cannabis products alongside specifically curated goods in an environment that encourages customer engagement and discovery.

The Dalwhinnie Farms cannabis boutique is located in the heart of downtown at 108 S. Mill St. and open from 10 a.m. to 6 p.m. daily, and 6-8 p.m. by appointment only. The store is operating in accordance with the State of Colorados COVID-19 mandates.

About Dalwhinnie Farms

Rooted in the San Juan Mountains in the heart of Colorados Rocky Mountain West, Dalwhinnie Farms is a purveyor of fine cannabis and lavish goods of unsurpassed quality. The companys Aspen retail boutique curates premium cannabis experiences, shared with welcoming Western hospitality and warmth. All of Dalwhinnies proprietary cannabis strains are meticulously grown at a purpose-built, advanced cultivation facility that shares its grounds with a 210-acre working equestrian ranch in southwest Colorado outside of Telluride. Come home to Dalwhinnie Farms: Connoisseur Cannabis. Elevated Moments. Learn more at

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HIV and Your Overall Health – POZ

As people with HIV live longer thanks to effective antiretroviral treatmentnearly half are now 50 or olderthey are prone to a host of additional health problems, known as comorbidities.

Common comorbidities among people with HIV include cardiovascular disease, diabetes and other metabolic conditions, liver and kidney problems, chronic lung disease, nonAIDS-related cancers, neurological conditions and frailty. HIV can also have a detrimental affect on mental health (see Your Mental Health).

People who have been living with HIV for many yearsespecially those who have experienced advanced immune suppression and those who have taken many antiretroviral medicationsare at greater risk for comorbidities. But these conditions also affect people with well-controlled HIV.

Some of these problems are associated with normal aging, but studies show that HIV-positive people tend to develop age-related conditions as much as a decade earlier than their HIV-negative counterparts.

Theres evidence that cardiovascular disease is more advanced in HIV patientssome estimates have said five to 10 years more advanced, says Steven Grinspoon, MD, a professor of medicine at Harvard Medical School and director of the Nutrition Obesity Research Center at Harvard. Frailty is associated with senescence and may increase vulnerability to aging-related processes, and reductions in physical function suggestive of early frailty seem to be very common in HIV patients.

Frailty is characterized by muscle and bone loss, weakness and decreased energy, and it can lead to reduced strength and endurance, heightened risk of fractures and progressive difficulty carrying out activities of daily life.

HIV and Inflammation

Chronic immune activation and inflammation appear to be a common thread tying together the various coexisting conditions seen in people living with HIV.

Even in people with sustained viral suppression and a near-normal CD4 T-cell count, chronic HIV infection triggers ongoing immune activation and persistent inflammation, which can take its toll throughout the body.

Even among patients with clinically well-controlled HIV, persistent virus in T-cell and macrophage reservoirs may lead to low-grade immune activation. Chronic immune activation may be associated with more generalized inflammation as well, Grinspoon says. Immune activation and inflammation may be appropriate mechanisms by which the immune system targets HIV, but these processes may cause collateral damage in multiple organs.

Persistently activated immune cells, including macrophages and monocytes, produce inflammatory cytokines, which can alter metabolism and blood vessel function and play a role in feedback loops that further increase inflammation.

Several comorbidities commonly seen in people with HIV are associated with metabolic syndrome, a cluster of conditionsinsulin resistance, abnormal blood lipid levels (dyslipidemia), high blood pressure (hypertension) and abdominal obesitythat raise the risk for cardiovascular disease and diabetes.

Whats more, some HIV-positive people develop a form of abdominal fat accumulation known as lipohypertrophy, which involves the buildup of visceral fat inside the abdomen surrounding the internal organs. This fat is metabolically active tissue that produces cytokines and hormones of its own.

With central fat accumulation, you can get inflammatory cells like macrophages that reside in the fat and release excess cytokines, which can draw in further monocytes and macrophages that produce substances that cause insulin resistance and dyslipidemia, Grinspoon explains. So the inflammation begets metabolic problems, and those metabolic problems beget further inflammation. These processes are intimately intertwined.

Conversely, although much less common in the age of effective antiretroviral treatment, some people with HIV may still develop wasting, which involved the unintentional loss of both fat and lean body mass (see What About Wasting?).

Heart, Liver and Kidney Disease

Numerous studies over the course of the epidemic have shown that people with HIV have a 50% to 100% greater risk of developing cardiovascular disease and its complications, including heart attacks and strokes.

Over time, plaquea combination of fat, cholesterol, calcium and immune cellscan build up on artery walls, a process known as atherosclerosis or hardening of the arteries. This narrows the vessels and restricts the flow of blood. Research suggests that plaque buildup happens at younger ages in people with HIV.

Whats more, bits of plaque can break off and lodge as clots in the coronary arteries that supply the heart muscle, leading to a heart attack, or in small blood vessels in the brain, causing a stroke. Plaque associated with ongoing inflammation appears especially prone to rupture, according to Grinspoon.

Inflammation can also wreak havoc on the liver. As antiretroviral treatment has dramatically reduced AIDS-related mortality, liver disease has become a leading cause of death for people living with HIV. Now that hepatitis B can be prevented with a vaccine and hepatitis C can be easily cured, fatty liver disease is becoming a major driver of advanced liver disease in HIV-positive and HIV-negative people alike.

Fatty liver disease goes along with obesity and excess weight, and it is also seen among those with diabetes and insulin resistance, as well as those with poor diet, says Grinspoon.

Chronic hepatitis B or C, fatty liver disease, heavy alcohol use and other causes of liver injury can trigger liver inflammation followed by fibrosis, or the buildup of scar tissue, as the organ tries to repair itself. Over years or decades, this can lead to serious complications, including cirrhosis, liver cancer and the need for a liver transplant. Studies have shown that this process seems to occur faster in people with HIV.

The kidneys, too, are vulnerable to the effects of inflammation. HIV-positive people have a higher rate of chronic kidney disease than their HIV-negative peers, with African Americans having the greatest risk. Certain antiretroviral medicationsin particular the older form of tenofovircan cause kidney problems in susceptible individuals. But even people who dont use this drug have a higher likelihood of impaired kidney function. Diabetes and high blood pressure, two components of metabolic syndrome, are the leading causes of kidney disease; hepatitis C coinfection also raises the risk.

Optimizing Overall Health

Regardless of which comorbidities you may have, maintaining a healthy lifestyle is key to optimizing your overall health.

Beyond HIV and the resulting inflammation, traditional risk factorsincluding smoking, high cholesterol, obesity and family historyare major contributors to elevated rates of heart disease and other comorbidities among people living with HIV. One study found that such traditional factors account for about a quarter of the excess risk of cardiovascular disease in this population.

Fortunately, many of these risk factors are under your control. Smoking, in particular, substantially raises the risk of heart disease, chronic lung disease and several types of cancer.

I want to emphasize that traditional risk factors matter, says Grinspoon. Stopping smoking is the number one most important thing you can do. Its really important because smoking may interact with inflammation and cause particularly severe disease.

Grinspoon is the principal investigator for a large trial called REPRIEVE that aims to learn more about cardiovascular disease among people living with HIV. The primary goal is to see whether a statin medication can prevent heart disease in this population. Statins not only lower cholesterol but also have anti-inflammatory properties, so they may offer a two-for-one benefit for people with HIV. Sub-studies will look at the effects of the statin on frailty and kidney function.

With 7,700 participants from 12 countries, REPRIEVE also has the potential to shed light on many other questions about the health of people living, and aging, with HIV. The study is now fully enrolled, and the primary results are expected in 2023.

In the meantime, to minimize the risk of heart disease, liver disease and other comorbidities, Grinspoon recommends a healthy diet, weight management, exercise and using medications to control hypertension, blood glucose and lipids. He suggests a balanced diet that includes polyunsaturated fatsfor example a Mediterranean dietand one that is low in salt and fructose, as fructose contributes significantly to fatty liver disease.

Exercise is important in two ways, he continues. One, it helps reduce weight, and two, its anti-inflammatory. It will help your blood pressure and help your glucose. Getting some exercise every day would be great.

Last but not least, its essential to start or stay on effective antiretroviral therapy to keep viral loadand the resulting inflammationas low as possible, he advises. I think thats the state of the art right now.

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Actress and Comedian Tiffany Haddish joins vitafusion Gummy Vitamins as Brand Ambassador –

vitafusion, Americas #1 gummy vitamin brand, announces today that Emmy-Award winning actress, comedian and author, Tiffany Haddish, will be joining the vitafusion team as a brand ambassador. Haddish will join vitafusion in highlighting both the importance of holistic wellness and a happy, healthy lifestyle and the significance of equal access to nutritious food choices for underserved communities.

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Actress and Comedian Tiffany Haddish joins vitafusion Gummy Vitamins as Brand Ambassador (Photo: Business Wire)

Tiffany Haddish has a long-term dedication and passion for creating positive change in communities and her undeniable wit complements vitafusions values perfectly. We are thrilled to work with someone who uses her personality and platform to educate and help others, shares Michael Vercelletto, Marketing Director for vitafusion. Our mission extends beyond offering great tasting vitaminswe are excited that Tiffany is joining us to encourage people to take a healthier step towards a happier tomorrow.

Haddish will be participating in vitafusions Fruit Tree Project, an eco-initiative which began in 2017 alongside the Fruit Tree Foundation to plant orchards which will provide nutrient-rich fresh fruit to underserved communities with limited or no access to fresh produce all with added benefits for the environment. In addition, Haddish will work on special projects for the remainder of the year increasing public awareness on the value of good nutrition as well as the importance of access to healthy, sustainable food.

What people eat and what they do can have a huge impact on their overall health. I'm excited to work with vitafusion to educate people about their health and remind them that not every child has equal access to healthy food which together we can help change, adds Tiffany Haddish.

Haddish, a New York Times Best Selling author and comedian, is best known for her roles in Girls Trip, Like a Boss, Night School and more. Haddishs journey and life experiences have inspired her comedy and sense of humor both on and off the stage.

About vitafusion:

vitafusion, Americas #1 Gummy Vitamin Brand, is the only gummy vitamin brand with a fusion of natural fruit flavors and ChefsBest award winning taste1 for select products.

For over 12 years, vitafusion has been supporting a happy and healthy lifestyle with our gummy vitamins and supplements. With more than 30 types of gummy vitamins available, vitafusion has been advancing the dietary supplement industry with two simple words: Vitamin Better.

[1] The ChefsBest Excellence Award is awarded to brands that surpass quality standards established by independent professional chefs.

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10 Shadiest Things Aang Did In Avatar: The Last Airbender | CBR – CBR – Comic Book Resources

Aang is the main character of Avatar: The Last Airbender. While there aren't a lot of instances of him being shady, but here's 10 that stand out.

Aang, the protagonist ofAvatar: The Last Airbender, exists at the peak of adorableness his charismatic overtures, his love for peace, his innatenegotiation skills, his vegetarianism, his lack of toxic masculinity, all these features make him one of the most, if not the most, beloved animated characters of all time.

RELATED: Avatar: Toph Vs Korra: Who Wins This Bender Fight?

In the course of his mission,or in general, Aang has gotten himself involved in some rather uncharacteristic activities and has also been responsible for a few dubious decisions. There aren't a lot of instances like these, but here are ten that stand out the most.

Aang learns about being the Avatar at the tender age of twelve (it's normally sixteen, but the monks had the impending war weighing on their minds.)

He behavesimmaturely in this situation and escapes on Appa after learning that he would be transferred to the Eastern Air Temple in order to keep him apart from Gyatso. Aang faces the weight of his responsibilities when he wakes up, though, given that he nowhas a hunter: the banished Prince Zuko seeking to get overa few of his daddy issues.

In the Earthbending city of Omashu, Aang and little Bumi used the "mail route" channels as a personal roller-coaster/slide, deriving immense enjoyment from the rush. In fact, when Team Avatar arrives there over a century later, he forces them to join him in the activity,completely unheedful oftheir terror.

More importantly, Aang fails to consider the consequences of any potential accident; even though he assures his friends that his Airbending can protect them, this doesn't mean that innocent people won't be endangered (like the Cabbage merchant, for example.)

Aang's daredevil behavior extended into the animal kingdom, and hisdesire for this specific brand of novelty might actually be considered a minor form of abuse.

RELATED: Avatar: The Last Airbender - Why Fans Agree The Great Divide Is The Worst Episode In The Series

He is interested in penguin-sailing and riding hog monkeys, whom he claims do not enjoy the experience but "that's what makes it fun!" Aang also surfs on the backs of the Elephant Koi around Kyoshi Island, heedless of the poor thing's consent. At least the Avatar Kuruk surfed on mountain waves generated by his own Waterbending.

As an Airbender of immense repute, Aang naturally finds the coarseness of Firebending uncomfortable at first. Still, when he generates his first flame under the sage guidance of Master Jeong Jeong, his enthusiasm exceeds his skill level and he accidentallyinjures Katara's hands.

It's great that Aang is immediately apologetic, but he takes his contrition too far by vowing to, "never Firebend again." On a positive note, Katara conceives her own healing powers while soothing her palms in flowing water.

When Katara and Sokka begin talking about their home and childhood, Aang is upset because he is unable to share that bond with them. Rather than have a discussion about being left out, he decides to prevent his friends from "abandoning" him to go see their long-lost father, Hakoda, by concealingthe map leading to his locationwithin his outfit.

Later, when Bato celebrates Team Avatar for their greatest features Aang being trustworthiness hisshame forces him to reveal his indiscretion, but Sokka and Katara are far too furious with him to care at this point.

It is a paradoxical quirk of nature that permits Aang to hold on to his friends against their will but simultaneously lets himforsake them whenever he's in a bad mood: even if they aren't at fault.

RELATED: Avatar The Last Airbender: 10 Non-Benders That Would Give Aang A Good Fight

Upon discovering that Sandbenders had stolen his best friend, he flies into a torrential rage and just Airbends off into the Si Wong desert, leaving the others to fend for themselves. When Toph confirms the identity of the kidnappers, Aang morphs into the Avatar State andwould have probably vaporized the settlement if Katara hadn't calmed him down.

When Team Avatar infiltrates Wan Shi Tong's mega-library, the owl spirit only allows them to rifle through its tomes and manuscripts only if they swear never to "abuse the knowledge" obtained from his collection.

Of course, Sokka has to slip up at some point, and when Wan Shi Tong finds out that they actually plan to use the upcoming solar eclipse to attack the Fire Nation, he tries to stop them from escapingwhile sinking the building deeper into the desert. It is understandable, given the extenuating circumstances, but the Avatar should never take a vow they do not plan to keep.

Aang figures out how to unlock his chakraswith the helpof Guru Pathik, a decrepit old man bursting with luminous wisdom. However, he cannot get himself to open the seventh and final one, because this means abandoning his earthly ties (and there is no way he can even dream of doing that to Katara.)

Aang does try, at least, but second, he catches a whiff of his love being in danger, he abandons his training and rushes to rescue her.At the end,the chakragets blocked by Azula's perfectly-timed lightning bending blast, anyway.

While "touring" through the Fire Nation, the gang comes across a play based on their adventures watching themselves interact on stage results in unique responses from everyone, but Aang is clearly the most impacted.

RELATED: Avatar: Toph Vs Fire Lord Ozai: Who Wins This Bender Fight?

When he sulks about his feelings to Katara, she says that she can't give him a clear answer with everything else going on. Aang lets his hormones do the talking and try to attack her with a kiss, but this only makes the situation worse because Katara is now angry with him for ignoring her agency.

Ozai's staggering Firebending capabilities aside, his tendency towards manipulating and backstabbing made it imperative that he be stopped; except, Aang refuses to accept this outcome,and searches for the perfect balance between what the world desires and what he does.

Luckily, he finds the answer to his conundrum in the form of a Lion Turtle and takes Ozai's bending away (a technique repeated on the Bloodbender Yakonein the sequel.) What would he have done it didn't have this option, though? Would he have broken Air Nomad code and committed murder? Or would he have let everything burn?

NEXT: Avatar: Uncle Iroh Vs Fire Lord Ozai: Who Wins This Fire Nation Fight?

Next Legend of Korra: 5 Couples Fans Loved (& 5 They Couldn't Stand)

Ajay's natural habitat is his bedroom, which means that his time is spent staring at his TV screen in a hypnotic coma. He tends to rant about the lack of quality programming in his life but the amount of content he consumes would make even Galactus gassy.

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Blue Band and Margarine’s Morph into Meaningfulness – Forbes Africa

By Larry Light, CEO Arcature Brand Consulting

Brand revitalization requires finding and satisfying a new, important customer need. Brand success requires being the best at something relevant and differentiated. It means never taking your eye off of changing customer needs.

As veganism and vegetarianism diets become more embedded into peoples lifestyles, anything plant-based is now perceived as good. Plant-based foods and beverages are seen as healthy and planet-friendly, an image that appears to override the idea that processing also takes place in their production.

Margarine is a non-dairy spread that was previously marginalized due to its hydrogenation, which turns polyunsaturates into saturates and trans-fatty acids. Because of hydrogenation, and its non-buttery texture and taste, margarine sales declined over the last decade. But, now margarine is morphing into healthier fare, as margarine is naturally plant-based. And, hydrogenation is no longer used to make margarine firmer and texturally closer to dairy butter. Current alternative butter brands made from plants contain healthy unsaturated fats. Brands, such as Blue Band, that were derided as pale non-dairy substitutes are now desired as manufacturers update and revise ingredients. Margarine has now become a darling of the alternative dietary regime crowds.

Margarine has an interesting past. Frances first president (1848-1852), Napoleon III, the nephew Napoleon I, asked for an alternative to butter due to food shortages that affected feeding the French army. A chemist, Hippolte Mege-Mouries created oleomargarine and the rest is history.

Unilever built a global margarine and spread business that included over 100 brands including Flora, I Cant Believe Its Not Butter, Blue Band. In 2017, after a very high-priced bidding war, investment firm KKR walked away with the prize, offering Unilever approximately US$7.7 billion (6.8 billion). The acquired business was set up under a new corporate entity called Upfield.

Ordinarily, the terms brand revitalization and private equity are not commonly used in the same sentence, so kudos to KKR. Rather than starve the former Unilever brands, KKR saw an opportunity that could not be overlooked: the appeal and profitability of plant-based foods. With some recipe changes and new marketing, KKR could leverage its portfolio as a healthier and more sustainable way to eat.

Some products were jettisoned, but this was to be laser-focused on the brands that fit the overarching portfolios new positioning. This new positioning is clearly articulated on Upfields website We are the largest plant-based consumer products company in the world and we have embarked on a journey to deliver a Better Plant-Based Future to the benefit of our customers and consumers alike. Along with this statement is the commitment to sustainability including a policy paper titled, A Better Plant-Based Future.

According to Financial Times, Upfield is determined to change the image of margarine. By focusing on the sustainability of margarine, Upfield is altering its ingredient lists by reducing each product to around five natural ingredients to create cleaner labels. Financial Times reports that originally KKR intended to strip out inefficiencies but decided on a new strategy after spotting consumer appetite for sexy plant-based foods. Apparently, Upfield made the correct decision, as its net sales grew 1.3% in 2019. And, The Good Food Institute reported sales of plant-based alternatives to meat, dairy and eggs rose 11% year on year in the US to $5 billion in 2019.

In the US, Earth Balance is one of Upfields biggest competitors. Earth Balance is a two-decades-old enterprise that makes vegan alternative butter spreads, nut butters and snacks. Its products are vegan, plant-based and non-GMO. The products have been designed to create a conscious, rewarding way of living. As part of its philosophy is its original commitment to being ethically plant-based. The palm oil it uses is a non-GMO, non-hydrogenated oil. Earth Balance is involved in the Roundtable on Sustainable Palm Oil (RSPO), committed to environmentally and socially responsible palm oil production.

Upfield is also focused on sustainable palm oil. Upfield states that it, too, sources 100% of its palm oil from physically certified sustainable sources. Additionally, as part of its investment, Upfield is pouring 50 million into a new Food Science Centre in Wageningen, the Netherlands, that will focus on sustainability, health, and taste in plant-based food, according to

The current eating scene is undergoing vast alterations. There are no clues as to which dining and cooking behaviors will last or fall away fast. What is clear is that the appeal of plant-based food alternatives is a growing customer desire. Revitalizing a brand by focusing on satisfying changing customer habits and attitudes keep brands relevant for enduring profitable growth.

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Blue Band and Margarine's Morph into Meaningfulness - Forbes Africa

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