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Ponce De Leon Health Announces Results Of Pilot Research Suggesting That Biological Age Can Be Reduced In Humans – PRNewswire

FERNANDINA BEACH, Fla., June 29, 2020 /PRNewswire/ --Ponce De Leon Health, Inc. ("Ponce de Leon"), a longevity company focused on reversing epigenetic aging, today announced the results of pilot research suggesting that Rejuvant LifeTabs, reduced the biological age of customers by an average of 8.5 years. The biological age was assessed by way of a DNA biomarker test that measures DNA methylation. Of the subjects in the analysis, two-thirds showed a statistically significant reduction in biological age. The analysis was based on data from subjects who had taken Rejuvant LifeTabs for a period of four to six months. Rejuvant, a dietary supplement, is Ponce de Leon's first commercial product.

The data were independently compiled by Dr. Yelena Budovskaya, Ph.D., co-founder and lead scientist of TruMe Labs, a pioneer in the emerging field of epigenetic aging testing. Ponce de Leon is a distributor of TruMe's TruAge Index, a take-at-home, non-invasive epigenetic age test. The subjects included in the analysis represent all 17 customers who had taken a TruAge test at the time of their first purchase of Rejuvant, as well as a second test after taking the supplement for four to six months. The TruAge Index measures DNA methylation, which is growing in acceptance by longevity researchers as an important biomarker of biological aging.

All formulations of LifeTabs contain the proprietary active ingredient LifeAKG,which was shown in recent pre-clinical animal studies to increase lifespan (the length of life) and healthspan (the length of healthy life) in mammalian models. Ponce de Leon has eight patents pending for inventions arising from its research and development activities.

Ponce De Leon is currently enrolling participants for a larger, randomized, double-blind, placebo-controlled clinical trial, to be conducted at Indiana University Medical Center later this year.

The Company's Chief Medical Officer, Francis R. Palmer, M.D., stated that "although at this stage we only have consumer data, these findings are very promising. We are only aware of one other published trial where researchers were able to show a reduction in biological age in humans as measured by DNA methylation. In this other trial, modest reductions in biological age were observed in a small number of subjects who were treated with a combination of prescription drugs for a year. The Rejuvant results are suggestive at this time but it showed a greater average reduction in biological age, achieved in six months, using non-prescription compounds." Added Palmer, "we expect our human clinical trial results to corroborate the encouraging data we have now, and we believe this will have a meaningful impact on both the scientific and consumer communities."

The Company's CEO and Founder, Tom Weldon, commented "the pilot research data appears to be consistent with our earlier mammal results but we appreciate the need for a more robust study to validate this data on lifespan and healthspan research. We look forward to conducting that study later this year and adding to these positive findings. The potential for Rejuvant to reverse epigenetic aging, as measured by DNA methylation testing and other measurable biological markers, may profoundly benefit not only the individuals who take the product, but also the economies and societies in which they participate and live."

Please see http://www.Rejuvant.com for more information on the groundbreaking science in LifeTabs.

About Ponce De Leon HealthPonce De Leon Health (www.PDLHealth.com) is a commercial-stage company focused on reversing epigenetic aging. Their work focuses on novel use of a combination of commonly used food ingredients developed independently by the world's leading non-profit institute studying aging. Their goal is to increase human healthspan, improve quality of life, and reduce the cost of providing late stage health care to customers. Their inaugural product, Rejuvant LifeTabs, is available at http://www.Rejuvant.com. You can also learn more about Rejuvant on Facebook, Twitter, and YouTube.

SOURCE Ponce De Leon Health

http://pdlhealth.com/

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Ponce De Leon Health Announces Results Of Pilot Research Suggesting That Biological Age Can Be Reduced In Humans - PRNewswire

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What’s the secret to a long, happy life? Forget kale and kettlebells – all you need is kindness – Independent.ie

The received wisdom on how to live a longer, healthier life involves eating organic, counting steps, popping vitamins. Which is all well and good, but according to a new book, Growing Young: How Friendship, Optimism And Kindness Can Help You Live To 100, it misses a vital aspect of our health - being positively connected to each other.

ritten by Canadian-Polish science journalist Marta Zaraska, the book presents a ton of scientific evidence which links longevity and good health with meaningful human interaction. She wrote it because she believes that "in the deluge of reductionist wellness news we've somehow lost the big picture, ignoring the things that matter the most for our longevity: relationships, emotions and the psyche."

Obviously, diet and exercise impact hugely on our health - that goes without saying - but so too do relationships, friendships, altruism, activism, and mindfulness. Zaraska illustrates, with ample scientific back-up, how improving close relationships lowers mortality risk by 45pc, working on empathy and kindness lowers it by 44pc, and volunteering and practising mindfulness each by 22pc - while exercise reduces it by 23pc.

Eating red meat increases risk of mortality by 29pc, while loneliness increases it by 26pc - which suggests going plant-based and working on your friendships will make you almost immortal. Pessimism, unhappiness and neuroticism each increase mortality risk by 14pc, whereas having a purpose in life, being agreeable, and feeling you have people you can count on reduces it by 17pc, 20pc, and 35pc respectively.

This is not to suggest that just because you're happily partnered and help out at the local animal shelter you should stop exercising or swap your five-a-day for deep fried Mars bars. It's about both. Nor is it about curing disease with positive thinking: "You can't rid yourself of cancer simply by repeating happy phrases in front of the mirror." No, this is about prevention, but instead of it being me-centred, it's we-centred.

"When you think about fad diets, miracle foods, supplements, exercise gadgets - there is tons of stuff to be purchased there," she says. "Someone is always trying to sell you something. But when it comes to 'soft' drivers of health like friendship, optimism or kindness, there is nothing to buy. No money to be made for anyone. And also the fact that we got so caught up in consumerism, into working long hours so that we can buy more and more stuff, bigger houses, fancier cars, bigger TVs and more clothes, certainly leaves less and less time to just be there for others, to sit down and think - how can I make the world a better place, how can I contribute to my community?

"Popping vitamin pills or chasing the best of organic baby arugula is very individualistic, very 'I' oriented. The only person you are thinking about is you. Whereas the mindful approach to health requires us to step back and think about the big picture, the world as a whole and your place in it.

"And even if still that first impulse here may be egoistic - you are motivated, after all, by your own health and longevity - I believe that for most people, taking a deeper look at how they spend their time and participate in the society can help them change for the better.

"And as a result we can all not only live healthier and longer, but also live in a better, nicer place, on a planet that maybe is not so ravaged by climate change and racism because we care more about each other and about our community.

"Several Japanese researchers with whom I've talked believe that one reason for their country's exceptional longevity is their collectivism, which makes people think more about others, belong to local associations, and participate in communal life."

On a practical level, Zaraska's findings come as a refreshing contrast to the relentless orthorexia of the wellness industry. Ditch goji berries and other miracle foods, ("There are no miracles"), and have a chat with your neighbour instead. "Skip fitness trackers, engage in some community gardening," she says. "If you are a bit overweight, stop obsessing: being social and mindful likely matters much more for your longevity."

Focus not (just) on kale and kettlebells, but on your immediate relationships, romantic and platonic. Avoid the Four Horsemen of relationship apocalypse - contempt, criticism, stonewalling and defensiveness. Instead, "Read books and articles on how to be a better partner and talk often about good things that happen in your daily life," says Zaraska. And when you're with your loved ones, no phubbing (snubbing them by being on your phone): "Put your phone away and cut down on social media."

Singing in a choir, disco dancing, and sports like group rowing, spinning or running are examples of synchrony, which in turn increases empathy as you synchronise with those around you. "Singing and dancing release social neurohormones such as endorphins and oxytocin," says Zaraska. As does laughing.

Avoid Botox, she says, as it freezes facial expression, which makes people harder to read. And empathy is all about mimicry, about being able to tune into another person's emotions and respond with facial feedback. Zaraska says this is harder to do if your facial muscles have been frozen. With empathy, she says "you can practise it the way you might practise tennis or yoga: the more you do it, the better you will become." Empathy leads to caring for others, and, Zaraska reminds us; "We evolved to care. Nature equipped us with systems that encourage giving. Benevolence is hardwired into the reward areas of our brainshelping others reduces stress, setting up a cascade of physiological changes that end up improving our health: reducing blood pressure, lowering inflammation, extending lives."

Empathy can not only make us live healthier and longer, but also help us be more tolerant, more open, and more caring for the world around us.

Even if your altruism is driven by selfishness - I will do a good deed for someone else because it benefits my own health - this is fine. Just do it anyway.

"It may not be very idealistic, but it sure works," says Zaraska. "Philanthropy is very contagious".

But what if you are a naturally curmudgeonly/ misanthropic/doomy, perhaps prone to neuroticism and not very conscientious? Personality impacts on longevity, which means 'don't worry be happy' is genuine medical advice. But what if you are not that type of person? Zaraska says you can cultivate personality traits that will impact positively on your health - "fake it to make it, set yourself small challenges of conscientiousness" (She means tidy your sock drawer, your desk top). Tackle neuroticism by sharing your problems with others, and - the real key to contentment - "try to find a deeper purpose."

This is, however, easier said than done, which is why she advocates some kind of mindfulness meditation: "Choose the mind-body technique you find most appealing, be it yoga, mindfulness, tai chi, and try to practice regularly and long-term; the more you stick with it, the more benefits you will get."

Especially if you are trying to implement slow but sure change across other areas of your life - less arguing with your partner, more community oriented activity, less stress, more disco dancing - having a meditative practise will enhance everything else. It really is magic. As is optimism, even when the world around us is going through all kinds of convulsions.

"I'm always hopeful - remember, optimism makes us live longer!" says Zaraska. "Maybe sometimes we humans need a bit of a catastrophe to push us in the right direction, refocus us on what really matters. I also believe the big thing here is empathy - and it's something we can train the way we train our abdominal muscles. Empathy can not only make us live healthier and longer, but also help us be more tolerant, more open, and more caring for the world around us." In addition to the advice offered by US academic Michael Pollan, "Eat food. Not too much. Mostly plants", Zaraska adds her own: "Be social, care for others, enjoy life."

It's priceless, and it's free.

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Dermal Fillers Market is Projected to Expand at a CAGR of 8.6% from 2018 to 2026 – 3rd Watch News

Transparency Market Research (TMR) has Published a new report titled, Dermal Fillers Market Global Industry Analysis, Size, Share, Growth, Trends, and Forecast, 20182026. According to the report, the global dermal fillers market was valued at US$ 2,584.9 Mn in 2017. It is projected to expand at a CAGR of 8.6% from 2018 to 2026. Expansion of the market can be attributed to technological advances leading to the development of newer hyaluronic acid dermal fillers with higher efficiency and long-lasting abilities, marketing strategies employed by market players, increasing awareness about these products on social media, and rising fad of anti-aging among people.

Biodegradables is anticipated to be a lucrative segment

The report offers detailed segmentation of the global dermal fillers market. Based on product, the market has been classified into biodegradable and non-biodegradable. The biodegradable segment dominated the market in 2017. It is likely to maintain its dominance during the forecast period. Biodegradable dermal fillers usually consist of purified dermal components derived from animal, human, or bacterial sources. Expansion of the segment can be attributed to the high safety profile of these fillers and recent technological advances that offer longevity on the usage of biodegradable fillers.

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Hyaluronic acid segment to expand at a robust CAGR

In terms of material, the dermal fillers market has been split into calcium hydroxylapatite, hyaluronic acid, collagen, poly-l-lactic acid, PMMA, fat, and others. The hyaluronic acid segment dominated the market in 2017. It is likely to maintain its dominance and expand at a high CAGR during the forecast period. More than 60% of dermal filler procedures performed globally are carried out with hyaluronic acid fillers. According to International Society of Plastic Surgeons (ISAPS), over 3,298,266 hyaluronic acid dermal filler procedures were performed annually. Additionally, technological advances have led to the development of various forms of hyaluronic acid dermal fillers, which differ according to the concentration of hyaluronic acid and the degree of crosslinking. These are known to enhance the longevity of the filler effect. These factors are anticipated to drive the market.

Rising fad of anti-aging driving the facial line correction treatment segment

Based on application, the dermal fillers market has been segregated into facial line correction treatment, lip enhancement, scar treatment, and others. The facial line correction treatment segment dominated the market in 2017. It is likely to continue the trend and expand at a high CAGR during the forecast period. Expansion of the segment can be attributed to the rising trend of anti-aging and increasing awareness about esthetic appearance among people. Additionally, facial line correction treatment appeals to varied age demographic, ranging from young adults to enhance their youthful features to middle-aged adults for volume restoration and older individuals to maintain age-related symptoms. Marketing strategies employed by market players, wherein celebrities promote their products, are fueling the desire among the population to mimic their favorite celebrities. This, in turn, is boosting the demand for facial line correction treatment procedures.

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Dermatology clinics to expand at high CAGR

In terms of end-user, the market has been split into hospitals, ambulatory surgical centers, dermatology clinics, and others. In terms of revenue, the hospitals segment dominated the market in 2017. It is likely to maintain the trend during the forecast period. However, the dermatology clinics segment is anticipated to expand at a robust growth rate during the forecast period. Robust expansion of the segment can be attributed to the increase in dermatology consultations and surge in preference for specialist dermatologists.

Growth in Asia Pacific to be driven by Japan and India

In terms of revenue, North America dominated the global dermal fillers market in 2017. The U.S. was the major revenue generating country in the region. Expansion of the market in the country can be attributed to a rise in the number of dermal filler procedures performed annually. According to American Society of Plastic Surgeons (ASPS) over 2.3 million dermal filler procedures were performed in 2017, an increase of over 3% over 2016. The market in Asia Pacific is expected to expand at a high CAGR during the forecast period. Expansion of the market in the region can be attributed to the increasing demand for dermal filler procedures in Japan, India, and China. Hyaluronic acid dermal filler procedures are highly common non-surgical procedures performed in various countries across Asia Pacific, including Japan, China, India, and Thailand.

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Strategic acquisitions is a key strategy adopted by key players

The report provides profiles of leading players operating in the global dermal fillers market. These players include Allergan plc, Sinclair Pharma (a subsidiary of Huadong Medicine Ltd), Merz Pharma GmbH & Co. KGaA, Nestle Skin Health (Galderma), BioPlus Co., Ltd., Bioxis pharmaceuticals, SCULPT Luxury Dermal Fillers LTD, Dr. Korman Laboratories Ltd., Prollenium Medical Technologies, Advanced Aesthetic Technologies, Inc., and TEOXANE Laboratories.

For instance, in 2014, Nestle acquired several dermatology brands owned by Canada-based pharmaceuticals group Valeant, which added a range of dermal fillers to the Nestle skincare business. Nestles skincare business was established through the acquisition of Galderma. In the same year, Allergan acquired Aline hyaluronic acid (HA) thread technology from Aline Aesthetics, a wholly owned subsidiary of TauTona Group.

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Our data repository is continuously updated and revised by a team of research experts so that it always reflects latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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Dermal Fillers Market is Projected to Expand at a CAGR of 8.6% from 2018 to 2026 - 3rd Watch News

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Genomic Biomarker Market Size, Share, Application Analysis, Regional Outlook, Growth Trends, Key Players, Competitive Strategies and Forecasts to 2025…

The ' Genomic Biomarker market' study now available with Market Study Report, LLC, delivers a concise outlook of the powerful trends driving market growth. This report also includes valuable information pertaining to market share, market size, revenue forecasts, regional landscape and SWOT analysis of the industry. The report further elucidates the competitive backdrop of key players in the market as well as their product portfolio and business strategies.

The Genomic Biomarker market report offers a thorough evaluation of this industry space and comprises of insights pertaining to the market tendencies including current remuneration, revenue predictions, market size and market valuation during the analysis timeframe.

A summary of the performance analysis of the Genomic Biomarker market is stated in the document. The study also provides with information concerning the key industry trends and the estimated growth rate of the market. The report delivers details regarding the growth opportunities and the inhibiting factors for this business vertical.

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This study specially analyses the impact of Covid-19 outbreak on the Genomic Biomarker , covering the supply chain analysis, impact assessment to the Genomic Biomarker market size growth rate in several scenarios, and the measures to be undertaken by Genomic Biomarker companies in response to the COVID-19 epidemic.

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Oncology, Cardiology, Neurology and Nephrology

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The major players covered in Genomic Biomarker are:, Bio-Rad, Almac, Thermo Fisher Scientific, Beckman Coulter, Epigenomics, Myriad Genetics, Human Longevity, QIAGEN, Roche, Pfizer, Agilent, ValiRx, Illumina, Empire Genomics, Personalis and Eagle Genomics

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Five organizations in southern Ariz. continuing to pursue bold environmental projects amid the pandemic – Arizona Daily Wildcat

Recently, environmental organizations have had to slow down much of their efforts to promote the safety of staff and an awareness of other pressing societal issues. Some believe that this is even resulting in opportunities for the government to sneak in and break apart environmental regulations, without the defense systems of environmental organizations.

The New York Times recently reported the Trump administration is in the process of rolling back on 34 environmental provisions, such as the National Environmental Policy Act and multiple Obama-era rules.

With COVID-19 and also the protests, people arent necessarily as focused on environmental issues that are happening right now, explained Harold Thomas, the associate director of the Watershed Management Group in Tucson. So, it's an easy time for government to roll back a lot of legislation.

Still, environmental initiatives held by a diverse range of organizations in southern Arizona are proving resilience during these difficult times. Five companies, Patagonia Area Resource Alliance, Sky Island Alliance, the Sonoran Institute, Zero-Mass Water and Local First AZ are showing that environmentalists can feel some optimism despite the whirlwinds hitting American society and the environment.

In Patagonia, the environmental watchdog organization Patagonia Area Resource Alliance has a history of keeping an eye on industrial mining in the area. For years, PARA has taken steps to hold industrial mining companies to the highest environmental standards, and this has not halted in times of the pandemic.

During the pandemic, PARA staff are continuing to monitor mining activities in a variety of ways, according to Anna Sofia, the communications and outreach coordinator. Since 2012, PARA has been tracking animals in the Patagonia Mountains with cameras to see what effects industrial mining is having on the wildlife and ecosystems. Sofia and another staff member have been continuously going out into the mountains to check these cameras.

Carolyn Shafer, PARAs mission coordinator, explained the importance of wildlife protection and monitoring in the area. She said that poor industrial mining practices could be very harmful to the wildlife and that it is a human responsibility to ensure protection.

An important thing that we need to do as humans is to assure the longevity of all species, said Shafer. The Patagonia Mountains are part of a region that has been identified by scientists as one of the top areas in the world, most in need of protection and study for species survival.

Similar to PARAs own wildlife tracking project in the Patagonia Mountains, the organization is also partnering with the Sky Island Alliance and the Mexican organization Naturalia Sonora to track wildlife along the border of Mexico. This project is meant to study the biodiversity in the region of border-wall expansion.

The organization has also been monitoring effects on the regions waterways. For example, they recently found what seems to be a leaking mine site left from historical industrial mining. Sofia describes that they have found acid mine-drainage that is flowing across a road in a canyon in the area. PARA is trying to monitor what impacts this may have on the water and reporting on it to the U.S. Forest Service.

We are actively out in nature keeping an eye on things, which has been really good, and we have still been able to do that throughout the pandemic, Sofia said.

In light of pandemic safety precautions, Sofia said that PARA is also hoping to create a multi-platform online educational program to engage the public on the risks and realities of industrialized mining. They are looking to fund much of this program with a recent grant received from Western Mining Action Network.

PARAs primary focus acting as a watchdog against poor industrial mining practices may be more important now than ever. Shafer explained that from the mid-1800s to around 1960, a total of 250,000 tons of ore was extracted from the Patagonia Mountains. Just one of the companies looking to mine now looks to remove about the same amount of ore from the mountains every 10 days.

Shafer and Sofia identified some of the major dangers that PARA looks to hold mining companies accountable for. One risk of poor mining practices is the fracturing and scarring of mountains, which would allow water from the Sonoita Creek Watershed to be diverted into those areas. Then, as the water picks up residue from mining and extracted metals, water sources important for humans and wildlife can become highly contaminated.

Additionally, Sofia noted that another worry is noise and light pollution from exploratory and underground drilling. These unnatural sounds and sights can negatively impact species in the area. For example, it can put burdens on threatened species of birds such as Mexican spotted owls and affect migration patterns, scattering populations and creating an inability to reproduce.

With everything going on in the world from environmental pressures like poor industrialized mining practices to the pandemic, Shafer stresses that PARA and the Patagonia community are staying resilient.

I have lived in this community for more than 20 years, and given the chaos of the times, there is no place nor any other group of people that I want to be with as we move through these multiple crises, Shafer said. This community has every skill set needed to co-create a thriving and resilient community and we are determined to do so.

The primary actor in the aforementioned Border Wildlife Study initiative that PARA is participating in was launched by Sky Island Alliance. Sky Island Alliance is a nonprofit in Tucson focused on protecting precious water resources, wildlife and creating awareness around the Sky Island natural region.

According to Emily Burns, the program director for Sky Island Alliance, the Border Wildlife Study was created in early March to document the wildlife community in the foothills of the Patagonia Mountains, the Huachuca Mountains and the San Rafael Valley. To do so, the organization and its project partners PARA and Naturalia Sonora have placed heat-activated and motion-activated cameras in the areas. Burns explained that these cameras are carefully arranged in a way that they can track both migrating species like black bears and mountain lions, and also the local diversity of animals.

The Sky Island Alliance formed this project in response to the Trump administrations border wall and its potential impacts on biodiversity. Burns explained that the federal government is furthering Trumps border wall project, and new waivers have been issued, allowing the construction to proceed without any environmental review.

We felt it was imperative to step in and collect information about what animals are actually here in the path of the coming border wall so that we can share that information with the public and go forward with eyes-wide-open about potential impacts to species that we care about, said Burns.

Though no border wall has been constructed yet in the region, Burns notes that past border wall studies have shown negative impacts on various species. She said that even flying species have been shown to be negatively affected, such as the once-endangered ferruginous pygmy owl.

Some of the negative effects described by Burns that could be the result of continued border wall construction include the division of natural habitats, an inability for migratory species to move and habitat fragmentation.

Burns said that in the short term, Sky Island Alliance hopes that this data can inspire people to stand up against border wall construction. In the long term, they hope that it will be baseline data that can help the public, voters and decision-makers be aware of the wildlife in the region.

Another Tucson-based organization that has been quite active in environmental initiatives and projects in the recent past is the Sonoran Institute. According to the institutes Senior Director of Programs, John Shepard, it is a community-based organization focused on connecting communities to the natural resources that nourish and sustain them.

Recently, the Sonoran Institute has been active in three major projects. These projects include the restoration of the Laguna Grande, upcoming Growing Water Smart workshops and the Living River Reports.

Since 2006, the institute has been partnering with U.S. and Mexican environmental organizations to restore Laguna Grande, a site on the Colorado River in Mexico. According to Shepard, it is the largest restoration site in the Colorado River delta.

The Sonoran Institute was inspired to restore the flow of water through the site, the natural habitat for riparian species and the groundwater for nearby impoverished areas. These are all factors that have been damaged by the Colorado River degradation.

Over many decades as Colorado River water has been dammed and diverted, the connection between the river and the sea was lost, and over 90% of the original delta was lost as well, Shepard said.

The second initiative, Growing Water Smart, is a training program for cities, towns and counties focusing on water efficiency as the Colorado River and Lake Mead lose the capacity to provide for people. Shepard said that the Sonoran Institute has trained around 30 communities so far. Much of this training is targeted toward community water leaders and public utilities.

It tries to get the people who are responsible for water supply, which tend to be your utilities, to talk and plan in coordination with people who are making decisions that will affect water demand in the future, Shepard said.

The third major project that is being pursued by the Sonoran Institute is the continued production of Living River Reports. These are annual reports documenting the condition of the Santa Cruz River.

For some time now, facilities have been restoring the flow of water in much of the Santa Cruz River by adding treated wastewater to it. The Sonoran Institutes reports aim to not only examine the health of the river as treated wastewater is deposited but also to make the case for improvements of treated wastewater quality.

Shepard said that over time, as these reports have been produced and treated wastewater quality has been upgraded, they have seen promising signs of improvement in river health. For example, they have recorded the return of the Gila topminnow, an endangered fish, to the Santa Cruz River.

Despite a series of changes that have had to be made, the Sonoran Institute and its initiatives have shown resilience during times of the COVID-19 pandemic. Thus, Shepard urges people in the environmental field to maintain a sense of optimism during this time.

Zero Mass Water, a Scottsdale based company, has been advancing the usage of hydropanels to provide safe, clean drinking water for industrial, commercial, residential and community applications. They mention how access to safe water is a human right for every community throughout the world.

Hydropanels are machines that collect water vapor from surrounding air, and then condense the vapor by increasing the humidity once it reaches the hydropanel. Panels are then arranged in such a way that it allows vapor droplets to collect and provide water. This water is then purified, ozonated and mineralized. This essentially makes the production of water an infinite and renewable source.

Zero Mass Waters initiatives look to provide the world with clean drinking water through a renewable energy source thus the Zero Mass title.

These hydropanels built by Zero Mass Water help provide water to areas across Arizona, even when various environmental challenges plague the community.

CEO of Zero Mass Water, Cody Friesen, stated that access to safe drinking water is a fundamental human right that is often too expensive, too wasteful, too extractive, and too scarce. Their hydropanels have helped to slow this problem by providing clean water to areas of Arizona that needed them the most.

With major burgeoning environmental challenges hurting Arizona such as excessive heat and water shortages, implementing a plan to obtain drinking water is important. According to the Fourth National Climate Assessment, water resources in the Southwest have already declined because of the growing population, deteriorating infrastructure and groundwater depletion, as well as human-induced climate change. Zero Mass Water is working to combat these challenges in an eco-friendly and cost-effective way.

Zero Mass Water looks to help communities not only in Arizona but across the world. With the climate changing the environmental frontier, it is uncertain to say what will happen to the main water sources that feed into major cities and rural areas.

This will be a risk for many due to the lack of availability of freshwater. Already, the United Nations indicated that 2 billion people live in countries experiencing high water stress. In response to these growing concerns, Zero Mass Water has implemented hydropanels in more than 40 other countries.

The pandemic has not slowed the companys bold efforts. Recent funding and expansion efforts with help from several organizations like BlackRock, Duke Energy and Breakthrough Energy, have allowed Zero Mass Water to further its hydropanel endeavors. According to Business Wire, they recently raised $50 million.

Phoenix-based organization focused on uplifting and empowering local businesses Local First AZ has partnered with the Tucson 2030 District, to launch a significant initiative for Tucson businesses. On May 20, Local First AZ helped to launch the Southern Arizona Green Businesses Alliance.

In recent years, Local First AZ has taken big steps to try and foster sustainable transformation in the southern Arizona economy. In 2018, the organization helped to launch Scale Up, a program for businesses to enrich sustainable actions through green workshops, networking and projects. In 2019, the organization launched the Arizona Green Business Program, a certification process aimed toward reducing environmental footprints.

Now, the introduction of the green alliance is a further step for Local First AZ. This alliance allows businesses to engage in three parts. The first part is the Green Business Leaders Program. This entry-level program provides a checklist for sustainable practices that will end with a follow-up consultation, recognition for sustainable leadership and more benefits such as marketing.

The next part is Scale Up, adopted from the original program started in 2018. This is an intermediate level program with more interactive learning opportunities.

The last part is the involvement in the Tucson 2030 District. Tucsons district is part of a collaborative effort among national districts to reduce water and energy consumption and emissions from transportation by 50% as soon as 2030.

According to Claire Kaufman, the sustainability program manager for Local First AZ, the program has been adjusted in many ways to adapt organizations to current circumstances.

COVID hit and we did a lot of adjustment on the programs to focus them even more on resiliency, so how businesses can be prepared in cases of disaster, Kaufman said.

Kaufman also described that adjustments have been made to the programs to integrate a more holistic education, including lessons on equity, social justice and environmental justice.

Its about making an economy that is environmentally resilient, economically resilient and socially resilient, Kaufman said.

A wide range of environmentally-concerned organizations are continuing to take strides toward improving the health of ecosystems, important natural resources and communities during the times of the pandemic.

The Patagonia Area Resource Alliance, the Sky Island Alliance, the Sonoran Institute, Zero Mass Water and Local First AZ are only five of the many organizations fighting against the odds to ensure environmental resilience despite everything that is happening.

For example, Watershed Management Group launched an initiative called Steward in Place, with the goal of connecting people to projects they can do from home that can help with an array of Tucsons environmental concerns.

According to Shepard, this resilience is at the core of environmentalism.

To be an environmentalist means youre an optimist."

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Asia’s First-ever Continuous Galvanized Rebar Manufacturing Facility Launched by Madhav KRG Group in Association With International Zinc Association,…

The first-of-its-kind facility, situated near Gobindgarh in Punjab, will produce a new product, Continuously Galvanized Rebar (CGR). CGRs are value added rebars for higher life and low maintenance of infrastructure to provide significant cost savings compared to other corrosion resistant rebar systems. It offers on-site formability of the finished product, superior corrosion resistance in concrete at a price cheaper than other corrosion resistant rebar (Epoxy Coating & CRS rebar).

With an annual capacity of over 30,000 tonnes, the plant will manufacture ZNCOAT TEMPCORE TMT BARS under the brand name - JYOTI - a name that is now synonymous with excellence in steel manufacturing. This will be the first brand in Asia to apply CGR technology that will not only be superior but will also enhance life span of the rebars thereby reducing the overall maintenance cost.

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Commenting about the new facility, Mr. Sudhir Goyal - Managing Director, Madhav KRG Group said, "Unlike painting and epoxy which are solely barrier-type coatings, CGRs are known to provide superior corrosion protection - both barrier and sacrificial - that further enhances the lifecycle of the underlying steel. I would like to thank the entire team of International Zinc Association and Hindustan Zinc Limited for their support in helping us bring this technology to India that will further help minimize the damage cause by corrosion and put India on the global map for its sustainable usage of zinc."

Addressing the audience, the steel minister Shri Dharmendra Pradhan assured the industry of full support from the government and deliberated on how zinc will play an important role towards building infrastructure for the nation. "As India is on its way to large-scale infrastructure expansions, use of galvanized rebar in construction is set to rise. India has a coastal line that extends over. 8000 kms. Coastal areas are prone to corrosion because of salty atmosphere leading to frequent maintenance requirement thereby adding to loss of material and impact on the productivity. Galvanizing ensures that the zinc coating is of a standard quality and offers resistance to erosion so that there is no risk of cracking due to bending. Galvanized steel and rebars are environment friendly and cost effective and possess properties that enhances life of any structure with minimum maintenance. The commissioning of the new CGR facility will further increase the usage of zinc in steel industry and will support the much awaited need of supplying galvanized rebar in the construction industry. I would like to congratulate the entire team International Zinc Association and Madhav KRG Group for their efforts in setting up the first-ever Continuous Galvanized Rebar (CGR) facility in Asia that will not only boost to domestic steel market but will also put India on the global map, aligning it to GoI's efforts in making India self-reliant or Aatmanirbhar Bharat."

Speaking on the occasion, Mr. Sunil Duggal - Group Chief Executive Officer-Vedanta Limited, & CEO-Hindustan Zinc said, "Infrastructure, especially around the coastal areas face maximum risk of corrosion owing to humidity and constantly changing climate. A long-term answer to this far-reaching problem is use of zinc protected steel during the structure's initial construction stages, i.e. Galvanized rebar that not only ensures longevity of the structures but is also significant initiative towards safety. It's time to mandate use of galvanized coated rebar's in all infrastructure projects.

"In the last ten years, Indian zinc demand grew at a compounded annual growth rate (CAGR) of 4-5%. However, usage of galvanized rebars and especially CGRs has been limited despite the fact that it bonds in par with concrete than uncoated rebar, thereby doubling the life of big concrete structures. As the government of India looks to strengthen Indian infrastructure, it calls for the need to adopt durable and proven corrosion protection methods, like structure galvanization. With continuous support from players like Madhav KGR and Hindustan Zinc Limited, we are confident of the shift to better national practices to help support India's efforts towards sustainable evolution." said Dr. Andrew Green, Executive Director, International Zinc Association (IZA) addressing the audience.

Galvanizing has been used for more than 100 years to protect structures exposed to different environmental conditions from corrosion.Realizing the importance of this technique, Honorable Prime Minister Narendra Modi had outlined a plan to spend about $1.5 trillion earlier this year, to upgrade and build infrastructure over the next five years to shore up economic growth, boosting the outlook for zinc, use of galvanized steel to prevent corrosion.

Over 1000 delegates (India and International) including ministry officials, opinion leaders, zinc producers, galvanizers, end users of galvanized products, industry executives from Railways, highway authorities, NHSRPL and design consultants attended the launch event.

About International Zinc Association

The International Zinc Association (IZA) was created in 1991 by a group of leading zinc & steel producers to represent the zinc industry globally. IZA's activities are to sustainably grow markets and maintain the industry's license to operate through effectively managed initiatives in research and development, technology transfer, and communication of the value of zinc. Operating internationally and locally through its regional affiliates, IZA helps sustain the long-term global demand for zinc and its markets by promoting such key end uses as corrosion protection for steel and the essentiality of zinc in human health and crop nutrition.

IZA's main programs are Sustainability & Environment, Technology & Market Development and Communications. Headquartered in Durham, North Carolina (USA), IZA also operates regionally through their offices in China, Europe, Latin America, North America, India and Southern Africa.

Photo: https://mma.prnewswire.com/media/1197554/CGR_launched_by_IZA_and_Madhav_KRG_Group.jpg

SOURCE International Zinc Association (IZA)

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Fast-Paced Growth in End-use Adoption to Propel Anti-Aging Medicine Market Revenue Growth – The Canton Independent Sentinel

Longer life-expectancy is a cumulative effect of a healthy lifestyle and favorable environmental conditions. A trend of continuously increasing life expectancy has been a witness since a decade, primarily because of advances in medical sciences and treatment of chronic life-threatening diseases, availability of clean water and environment and other factors. This trend is projected to further show even more exponential growth graph owing to the anti-aging medicines, stem cell therapeutics, genetic screening and interventions, and high-tech biomedicines. American Academy of Anti-Aging Medicine claimed that anti-aging medicines can add up to 10-20 years to the life expectancy of a human. Today, a combination of calorie-restricted diet, regular exercise, and anti-aging medicines are claimed to slow the process of senescence and aging. Various medicines used against the treatment of acute or chronic diseases can be considered as anti-aging medicines, however, to define anti-aging medicine market we have considered only the drugs that are directly prescribed and used for delaying the effects of aging.

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The constantly growing demand to look young in old individuals and to remain young and youthful in young people drive the anti-aging market. The influence of aesthetics from the fashion and television industry propel the demand to retain the features and energy of younger age in old people. Additionally, the increasing number of anti-aging medicine manufacturers in the decade contribute to higher availability of the anti-aging medicine resulting in expansion of the global anti-aging medicine market. However, skeptical approach to anti-aging medicine as being an external stimulator of cell-cycles is a restraint to the expansion of anti-aging medicine market.

The global Anti-aging medicine market is segmented on basis of product type, age group, distribution channel, and region:

The rising demand for beauty consciousness amongst people and the desire to stay young is the primary factor fueling the growth of anti-aging medicines in the market. The acclaimed benefits of the products and affordability along with regional presence compel the demand for anti-aging medicine in the global market. Hormonal replacement therapy segment in product type is expected to account maximum market share in the terms of revenue in the global anti-aging medicine market. However, antioxidant therapy segment in product type is expected to grow with the highest CAGR over the forecast years owing to the rising awareness about the plethora of benefits of antioxidants in anti-aging among the public. On the basis of the route of administration, the global anti-aging medicine market is segmented as oral, injectable and topical, out of which oral segment is expected to generate maximum revenue share over the forecast period. As per the distribution channel, the global anti-aging medicine market is segmented as hospital pharmacies, retail pharmacies, e-commerce, and drug stores. The e-commerce segment in the distribution channel is estimated to grow with the highest CAGR over the forecast time.

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Regionally, the global anti-aging medicine market is segmented into five key regions viz. North America, Latin America, Europe, Asia Pacific, and Middle East & Africa. North America anti-aging medicine market is projected to account for the largest market share in the terms of revenue in the global anti-aging medicine market owing to the higher healthcare expenditure and presence of numerous manufacturers. Europe is expected to hold the second largest share in the global anti-aging medicine market during the forecast period because of the growing geriatric population and higher spending on healthcare products and supplements. MEA anti-aging medicine market is expected to witness sluggish growth over the forecast time owing to the limited presence of manufacturers and lower healthcare expenditure. Asia Pacific is projected to grow with the highest CAGR over the forecast years in the global anti-aging medicine market due to higher demand from end users and regional penetration of the key players in the region.

Some of the players operating in the global anti-aging medicine market are Pfizer, Evolution GmbH, Himalaya Global Holdings Ltd., Cipla Limited, Mylan Laboratories, Novartis, Merck Group, Vitabiotics, William Ransom & Son Holdings Plc, Uni-Vite Healthcare and Health Made Easy Limited amongst others.

Rustil is a regular contributor to blog , Specializing in Industry Research and Forecast

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These are the winners of 2020 Global Fact Awards – Poynter

The International Fact-Checking Network highlights some of the most impressive fact-checks published every year with the Global Fact Awards. In 2020, after counting 2,037 votes received between June 22 and 24, the IFCN is proud to announce the winners.

Rappler (Philippines): FALSE: Clean semen a cure for COVID-19

This fact-check examined a video from April where a man dressed as a doctor suggested a novel remedy for treating COVID-19. Using a study from the U.S. National Library of Medicine, the video claims the antibacterial properties of semen make it useful as both a COVID-19 treatment and as a hand sanitizer.

Rappler poked holes in this claim by pointing out the study does not mention COVID-19. Rappler also referred a similar fact-check by fellow CoronaVirusFacts Alliance member Taiwan Fact-Check Center. Finally, Rappler noted that the man, Anacleto Belleza Millendez, runs a Facebook page advertising semen-based anti-aging cream.

Washington Post Fact Checker (United States): Moroccan police justified a brutal beating. Video contradicts their narrative.

The Washington Post Fact Checker came across a video of a Moroccan man being beaten by local police. The authorities later released a statement justifying their use of force saying the man had tried to ram them with his car. The man, Walid El Batal, was a Morrocan journalist on his way to cover the release of a political prisoner in the disputed Western Sahara region.

The Post interviewed eyewitnesses, reviewed cell phone video and cross-referenced their accounts with Google Earth images to find inconsistencies in the polices story. The car El Batal drove had no frontal damage, but did have a dent in its side. The police cars bumper was damaged, suggesting it was the police who rammed El Batal rather than the other way around.

Taiwan Fact-Check Center: Bomb Disposal on Election Night

This fact-check involved a video from Taiwanese elections in January, which claimed to show someone was rigging the voting system. CNN reported in January that some in Taiwan feared interference from China, so Taiwan Fact-Check Center worked quickly to debunk this claim.

They watched the video that supposedly showed a man messing with a tallying system, and discovered he was simply tallying the votes being read out by a woman off screen. This fact-check was quickly reported by Taiwanese media, which calmed tensions over potential election interference.

As announced, each of the winners will receive a $500 prize.

For the first time since 2018, when the Global Fact Award was launched in Rome, the IFCN is offering a financial prize.

Also for the first time, the IFCN decided to have a more structured voting system. In prior years, both the publics and the fact-checking communitys votes counted equally. Now, the IFCN implemented a weighted system modeled on the NBA All-Star game balloting process.

Each fact-checking organization got only one vote, which was weighted to count for of the final total. All other votes counted for the remaining . After both the fan and organization votes were tallied, the fact-checks were ranked from first to last. The IFCN used this formula to decide the final rankings and winners.

You can see the full results here.

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FDA Slaps Stem Cell Firm Linked to Nebraska Infections – MedPage Today

The FDA has identified Las Vegas-based EUCYT Laboratories as the company whose exosome products sickened patients in Nebraska late last year, according to a recent warning letter.

The agency also warned EUCYT for marketing an exosome product COVIXO that it claimed could treat COVID-19.

Paul Knoepfler, PhD, a stem cell expert at the University of California Davis, wrote in a blog post that the June 4 letter "is one of the more lengthy warnings that I've seen recently" as it highlights some 13 "major observations."

"Remarkably, the letter uses forms of the words 'fail' or 'failure' 30 times," Knoepfler wrote.

Last December, public health officials in Nebraska warned clinicians that several patients had developed severe infections after receiving unapproved exosome products. Fewer than five patients had become seriously ill, with some developing sepsis.

At the time, Nebraska public health officials said all patients had received an exosome product derived from C-sectioned placentas; the FDA then issued a "public safety notification" about unnamed exosome products. EUCYT's involvement only became public with the June 4 warning letter, which stated that "FDA issued that public safety notification following multiple reports of serious adverse events experienced by patients who were treated with XOsomes."

When FDA conducted inspections at EUCYT's manufacturing plant last November, it found violations including deficient donor eligibility practices, unvalidated manufacturing processes, deficient environmental monitoring, and inadequate aseptic practices.

From April 2018 to November 2019, EUCYT failed to thoroughly investigate 152 sterility failures, according to the FDA warning letter. In those cases, it identified the contaminating organism but destroyed the batches without more detailed investigations.

It also failed to implement corrective or preventive actions in those cases. In one instance, FDA said, the company failed to investigate one lot of product after it failed sterility testing for E. coli. It discarded the lot without conducting a thorough investigation of other lots manufactured on the same day -- and FDA found that another lot made that day was later tied to a report of a patient testing positive for E. coli.

EUCYT chief executive officer Travis Bird did not return a MedPage Today request for comment.

As for the company's COVID-19 exosome product, the FDA warning letter quotes the company's website as saying the product "drives cellular functionality including augmenting the type 1 interferon pathway ... that is important for anti-SARS-CoV-2 activity." It also claims that the "unique mechanism of action for COVIXO enables each patient to generate their own adaptive immune response against SARS-CoV-2, including memory T cells and antibodies, which will further protect each patient from subsequent exposures and infections."

A document with these claims was downloadable from the EUCYT website on June 1, but no longer appears.

Other companies have marketed exosomes for COVID-19 as well, including one California-based company that pushed inhaled exosomes that could be delivered directly to patients' doorsteps so they didn't have to violate stay-at-home orders.

FDA said neither of EUCYT's exosome products would qualify for the agency's homologous use exemption and must be regulated as drugs that would need to be reviewed and approved. Neither product currently has an approved biologics license application or an investigational new drug application (IND) on file, although a EUCYT press release on May 8 said an IND for COVIXO was "pending approval."

The company markets a host of other stem cell products derived from birth tissue, which FDA also said do not meet criteria for the homologous use exemption and must be regulated as drug products. These include its VidaCord, VidaGel, VidaStem, and VidaFlo product lines.

Following the June 4 warning letter, EUCYT no longer lists available products on its website. Visitors are now invited to contact the company for information.

MedPage Today has previously reported on a growing trend of hospitals implementing placenta donation programs and potential links to unapproved stem cell products.

While exosomes are being evaluated in legitimate research studies, some clinics -- often those peddling unapproved stem cell therapies -- are offering exosome therapy for all kinds of conditions. One site for a clinic in San Diego describes the treatment as "the ultimate anti-aging hack." Delaware Integrative Medicine advertises exosome therapy as being helpful for patients with "chronic inflammation, autoimmune disease, Lyme disease, and other chronic degenerative diseases."

But stem cell researchers say exosomes -- packages of proteins and RNAs that can be transferred from cell to cell -- are nowhere near ready for routine clinical use.

"Overall, it's crystal clear that exosomes are generally drug products requiring pre-approval from the FDA prior to use in patients," Knoepfler wrote on his blog. "And the agency is willing to take relatively quick action against non-compliant exosome firms."

Last Updated June 23, 2020

Kristina Fiore leads MedPages enterprise & investigative reporting team. Shes been a medical journalist for more than a decade and her work has been recognized by Barlett & Steele, AHCJ, SABEW, and others. Send story tips to k.fiore@medpagetoday.com. Follow

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The Best Online Facial Consultations and Skin-Care Classes – Coveteur

Who knew that a celebrity facialist could be just a click away?

Imagine: Youre covered in terry cloth, waiting for your aesthetician on their padded table in a dark, quiet room. They cleanse your skin and with the gentlest tone of voice tell you exactly which treatments will return your face and dcolletage to their most even, glowiest state. As they start to massage your forehead and jowls, your mind slips away in total bliss, each layer of product feeling like a weighted blanket for the soul. Can you tell that we really miss professional facials?

Although there are some skin-care treatments that we can manage at home, like extractions and a series of masks, theres nothing quite like the touch of a trained professional. Even with stay-at-home orders slowly lifting throughout the world, some of you might still have a few weeks, if not months, before you can safely visit your favorite facialist again. So how do we up the ante and deliver those same spa-like cleansing, toning, and brightening results from home? Luckily, aestheticians and skin-care studios have taken to the internet to provide their expertise and step-by-step instructions via email or Zoom. These can range from one-on-one consultations to group classes depending on your skin type or concern. Not only are you giving your skin some much-needed love and attention, but youre also supporting the people whose businesses might still be closed for the foreseeable future. Its a win-win!

If youre looking to gain insight from industry professionals on what to do with your skin during a quarantine, check out seven of our favorite online skin-care courses and consultations right now.

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The founders of Clearstem Skincare, Kayleigh Clark and Danielle Gronich, understand that there are more factors than just your cleanser that may be causing acne. Ditch Your Acne determines the root cause of acne in an individual by assessing a clients gut health, nutrition, supplements, products, hormones, and lifestyle. Whether youre looking for a summer glow-up, youre a new mom, a bride-to-be, or a healthcare practitioner, there is a specific course tailored to meet every one of your needs.

Rene Rouleau is no stranger to online skin care; Rouleau initially launched My Skin Prescription in 2012. The six-week program includes video consultations with an aesthetician, where they help an individual tackle their top skin concerns through skin assessments, product recommendations, and nutritional advice. Pro tip: Your consultation with an aesthetician is free when you purchase $100 in skin-care products at the time of your appointment. You may as well buy the productsall of Rene Rouleaus formulas are legendary.

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Although gua sha has been used in traditional Chinese medicine for years, it has gained popularity here in the States in the past few years. Heres why: It rids the skin of fluid buildup, stimulates blood circulation, and helps to massage tension away from muscles. Skin looks more taught and sculpted, especially if you use your tool regularly. For those of you who are struggling to master the proper techniques of gua sha, consider the Gua Sha workout from Face Gym. They use a variety of electrical and manual tools to sculpt, massage, and depuff your face, so you look more rested and glowy, fast.

Have you ever wondered what it would be like to receive a facial by the same person who treats both Rooney Mara and Uma Therman? Well, we have some exciting news for youcelebrity facialist (and skin-care guru) Joanna Czech is now offering online consultations, where you can speak with her about your skin-care goals. After Czech analyzes your skin condition, you will receive an email with an at-home skin-care routine specifically tailored for you, including product recommendations and best practices. Youll look like a movie star in no time.

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Despite living in quarantine, many people are still finding it challenging to reserve an hour or two for themselves, let alone to attend a Zoom facial meeting. The Healthy Aging Consultation at Art of Skincare is done through email only, making it extremely accessible to everyone despite your busy schedule. Aesthetician Jeana determines the perfect at-home anti-aging routine based on their Healthy Aging quiz and photos of your skin.

Monastery is a skin-care brand founded by Athena Hewett, an aesthetician, massage therapist, and herbalist who uses holistic approaches to heal and restore balance in the skin. She also created Shelter Facials, which are step-by-step guides to at-home treatments using Monastery products. We recommend the balancing glow facialit properly exfoliates and restores your skin to an otherworldly glow.

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